High-dose insulin in the treatment of antihypertensive overdose

Hospital Pharmacy

Volumn 43, Issue 3, 2008, Pages 206-209

  Clark, Emily G ^a   Nykamp, Diane L ^b   Nguyen, Vy V ^a  

^a MERCER UNIVERSITY   (United States)

^b MERCER UNIVERSITY   (United States)

Author keywords

Dextrose; High dose insulin; Potassium (HDIDK)

Indexed keywords

ADRENALIN; ALCOHOL; BENZODIAZEPINE DERIVATIVE; CALCIUM; CALCIUM CHANNEL L TYPE; ESCITALOPRAM; GLUCAGON; GLUCOSE; INSULIN; MAGNESIUM SULFATE; OLMESARTAN; POTASSIUM; TRANDOLAPRIL PLUS VERAPAMIL;

ADULT; ARTICLE; CALCIUM TRANSPORT; CASE REPORT; CORONARY BLOOD VESSEL; DRUG MEGADOSE; DRUG OVERDOSE; ELECTROCARDIOGRAM; FEMALE; HEART MUSCLE CELL; HOSPITAL DISCHARGE; HUMAN; HYPOINSULINEMIA; HYPOTENSION; INOTROPISM; INSULIN INFUSION; LIQUID; SHOCK; TREATMENT DURATION; TREATMENT OUTCOME; VASODILATATION;

EID: 67651102909     PISSN: 00185787     EISSN: None     Source Type: Journal    
DOI: 10.1310/hpj4303-206     Document Type: Article

References (16)

1. Reynolds NA, Wagstaff AJ, Keam SJ. Trandolapril/verapamil sustained release: a review of its use in the treatment of essential hypertension. Drugs. 2005;65(13):1893-1914. (Pubitemid 41258141)
2. Watson WA, Litovitz TL, Rodgers GC Jr, et al. Annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emer Med. 2003;21(5):353-421.
3. st ed. Philadelphia, PA; WB Saunders Company: 2001:370-378.
4. Boyer EW, Shannon M. Treatment of calcium channel blockers intoxication with insulin infusion. N Engl J Med. 2001;344(22):1721-1722. (Pubitemid 32479976)
5. Lheureux PE, Zahir S, Gris M, Derrey AS, Penaloza A. Bench-to-bedside review: hyperinsulinaemia/euglycemia therapy in the management of overdose of calcium-channel blockers. Crit Care. 2006;10(3):212. (Pubitemid 47086871)
6. Tovar JL, Bujons I, Rui JC, Ibañez L, Salgado A. Treatment of severe combined overdose of calcium antagonists and converting enzyme inhibitors with angiotensin II. Nephron. 1977;77(2):239.
7. st ed. Philadelphia, PA; WB Saunders Company: 2001:397-406.
8. Salhanick SD, Shannon MW. Management of calcium channel antagonist overdose. Drug Saf. 2003;26(2):65-79.
9. Shepherd G, Klein-Schwartz W. High-dose insulin therapy for calcium-channel blocker overdose. Ann Pharmacother. 2005;39(5):923-930. (Pubitemid 40570672)
10. Gokel Y, Paydas S, Acikalin A, Bozkurt A. High-dose verapamil + trandolapril-induced thrombotic microangiopathy. Haematologia (Budap). 2002;32(3):281-285. (Pubitemid 36124116)
11. Shepherd G. Treatment of poisoning caused by B-adrenergic and calcium channel blockers. Am J Health Syst Pharm. 2006;63(19):1828-1835. (Pubitemid 44477454)
12. Isbister GK. Delayed asystolic cardiac arrest after diltiazem overdose; resuscitation with high dose intravenous calcium. Emerg Med. 2002;19(4):355-357.
13. Lam YM, Tse HF, Lau CP. Continuous calcium chloride infusion for massive nifedipine overdose. Chest. 2001;119(4):1280-1282.
14. Bailey B. Glucagon in b-blocker and calcium channel blocker overdoses: a systemic review. J Toxicol Clin Toxicol. 2003;41(5):595-602. (Pubitemid 37102385)
15. th ed. New York, NY; McGraw-Hill; 2006.
16. Boyer EW, Duic PA, Evans A. Hyperinsulinemia/euglycemia therapy for calcium channel blocker poisoning. Pediatr Emerg Care. 2002;18(1):36-37. (Pubitemid 34174344)