The R336Q mutation in human mitochondrial EFTu prevents the formation of an active mt-EFTu·GTP·aa-tRNA ternary complex

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1792, Issue 8, 2009, Pages 791-795

  Valente, Lucia ^a   Shigi, Narumi ^b   Suzuki, Tsutomu ^b   Zeviani, Massimo ^a  

^a DEPARTMENT OF NEUROSURGERY   (Italy)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Mitochondrial translation; mt EFTu binding activity; mt EFTu mutation

Indexed keywords

ELONGATION FACTOR TU; GUANOSINE TRIPHOSPHATE; MITOCHONDRIAL DNA; MITOCHONDRIAL RNA; MUTANT PROTEIN; TRANSFER RNA;

AMINOACYLATION; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; GENE MUTATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; IN VITRO STUDY; MOLECULAR MECHANICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROCESSING; RNA TRANSLATION; TRANSLATION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CATTLE; DNA, MITOCHONDRIAL; FEMALE; GUANOSINE TRIPHOSPHATE; HUMANS; INFANT; MACROMOLECULAR SUBSTANCES; MITOCHONDRIAL ENCEPHALOMYOPATHIES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PEPTIDE ELONGATION FACTOR TU; POINT MUTATION; PROTEIN BIOSYNTHESIS; RNA, TRANSFER, AMINO ACYL;

EID: 67651097815     PISSN: 09254439     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbadis.2009.06.002     Document Type: Article

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