Haemophilus influenzae serotype b vaccine failure: What is the significance of antibody levels?

Clinical Infectious Diseases

Volumn 49, Issue 3, 2009, Pages 381-382

  Spanjaard, Lodewijk ^a,c   Rijkers, Ger T ^b  

^a Center for Infection and Immunity Amsterdam   (Netherlands)

^b ST ANTONIUS HOSPITAL   (Netherlands)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

HAEMOPHILUS INFLUENZAE VACCINE;

HAEMOPHILUS INFECTION; HEALTH PROGRAM; HUMAN; IMMUNIZATION; NOTE; PRIORITY JOURNAL; SEROTYPE; UNITED KINGDOM; VACCINE FAILURE;

ADOLESCENT; ANTIBODIES, BACTERIAL; BACTERIAL CAPSULES; CHILD; CHILD, PRESCHOOL; GREAT BRITAIN; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; HAEMOPHILUS VACCINES; HUMANS; INFANT; VACCINES, CONJUGATE;

EID: 67651091366     PISSN: 10584838     EISSN: None     Source Type: Journal    
DOI: 10.1086/600293     Document Type: Note

References (6)

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2. Ladhani S, Heath PT, Ramsay ME, et al. Long- term immunological follow-up ofchildren with Haemophilus influenzae serotype b vaccine failure in the United Kingdom. Clin Infect Dis 2009; 49:372-80 (in this issue).
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5. Kelly DF, Moxon ER, Pollard AJ. Haemophilus influenzae type b conjugate vaccines. Immunology 2004; 113:163-74.
6. Schouls L, van der Heide H, Witteveen S, et al. Two variants among Haemophilus influenzae serotype b strains with distinct bcs4, hcsA and hcsB genes display differences in expression of the polysaccharide capsule. BMC Microbiol 2008; 8:35.