Preventing healthcare-associated Aspergillus infections: Review of recent CDC/HICPAC recommendations

Medical Mycology

Volumn 47, Issue SUPPL. 1, 2009, Pages

  Weber, David J ^a   Peppercorn, Amanda ^a   Miller, Melissa B ^a   Sickbert Benett, Emily ^a   Rutala, William A ^a  

^a UNIVERSITY OF NORTH CAROLINA HOSPITALS   (United States)

Author keywords

Aspergillus; Guidelines; Healthcare associated; HICPAC; Outbreaks

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B LIPID COMPLEX; ITRACONAZOLE; POSACONAZOLE;

AIRBORNE FUNGUS; ASPERGILLOSIS; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; ASPERGILLUS GLAUCUS; ASPERGILLUS NIGER; ASPERGILLUS ORYZAE; ASPERGILLUS TERREUS; ASPERGILLUS USTUS; CONSTRUCTION WORK; EPIDEMIC; HEALTH CARE FACILITY; HOSPITAL INFECTION; HUMAN; INFECTION CONTROL; INFECTION RISK; LOW DRUG DOSE; LUNG ASPERGILLOSIS; MOLECULAR TYPING; PRACTICE GUIDELINE; PUBLIC HEALTH SERVICE; REVIEW; SKIN INFECTION; CROSS INFECTION; UNITED STATES;

ASPERGILLUS; FUNGI;

ASPERGILLOSIS; CENTERS FOR DISEASE CONTROL AND PREVENTION (U.S.); CROSS INFECTION; GUIDELINES AS TOPIC; HUMANS; UNITED STATES;

EID: 67651090088     PISSN: 13693786     EISSN: 14602709     Source Type: Journal    
DOI: 10.1080/13693780802709073     Document Type: Review

References (67)

1. Manuel RJ, Kibbler CC. The epidemiology and prevention of invasive aspergillosis. J Hosp Infect 1998; 39: 95-109.
2. Singh N, Paterson DL. Aspergillus infections in transplant recipients. Clin Microbiol Rev 2005; 18: 44-69.
3. Maschmeyer G, Haas A, Cornely OA. Invasive aspergillosis: Epidemiology, diagnosis and management in immunocompromised patients. Drugs 2007; 67: 1567-1601.
4. Warnock DW. Trends in the epidemiology of invasive fungal infections. Jpn J Med Mycol 2007; 48: 1-12.
5. Ader F, Nseir S, Le Berre R, et al. Invasive pulmonary aspergillosis in chronic obstructive pulmonary disease: An emerging fungal pathogen. Clin Microbiol Infect 2005; 11: 427-429.
6. Bulpa P, Dive A, Sibille Y. Invasive pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Eur Respir J 2007; 30: 782-800.
7. Winkelstein JA, Marino MC, Johnston RB Jr, et al. Chronic granulomatous disease. Report on a national registry of 368 patients. Medicine (Baltimore) 2000; 79: 155-169.
8. Almyroudis NG, Holland SM, Segal BH. Invasive aspergillosis in primary immunodeficiencies. Med Mycol 2005; 43 (Suppl. 1): S247-S259.
9. Ballard J, Edelman L, Saffle J, et al. Positive fungal cultures in burn patients: A multicenter review. J Burn Care Res 2008; 29 213-221.
10. Meerssemam W, Vandercasteele SJ, Wilmer A, Verbeken E, Peetermans WE, Van Wijnaerden E. Invasive aspergillosis in critically patients without malignancy. Am J Respir Crit Care Med 2004; 170: 621-625.
11. Khasawneh F, Mohamed T, Moughrabieh MK, Lai Z, Ager J, Soubani AO. Isolation of Aspergillus in critically ill patients: A potential marker of poor outcome. J Crit Care 2006; 21: 322-327.
12. Vanderwoude K, Blot S, Benoit D, Dupuydt P, Vogelaers D, Colardyn F. Invasive aspergillosis in critically ill patients: Analysis of risk factors for acquisition and mortality. Acta Clin Belg 2004; 59: 251-257
13. Winston DJ, Maziarz RT, Chandrasekar PH, et al. Intravenous and oral intraconazole versus intravenous and oral fluconazole for long-term antifungal prophylaxis in allogeneic hematopoietic stem-cell transplant recipients: A multicenter, randomized trial. Ann Intern Med 2003; 138: 705-713.
14. Chiller TM, Marr K, Kontoyiannis DP, et al. The epidemiology of invasive aspergillus (IA) infection among organ transplant recipients in the U.S. 2001-2006: Review of TRANSNET. In Program and Abstracts, 3rd Advances Against Aspergillus, Miami, FL, 2008 [abstract number 87, page 179].
15. Warris A, Gaustad P, Meis JFGM, Voss A, Verweij PE, Abrahamsen TG. Recovery of filamentous fungi from water in a paediatric bone marrow transplant unit. J Hosp Infect 2001; 47: 143-148.
16. Anaisse EJ, Stratton SL, Dignani MC, et al. Pathogenic Aspergillus species recovered from a hospital water system: A 3-year prospective study. Clin Infect Dis 2002; 34: 780-789.
17. Anaissie EJ, Costa SF. Nosocomial aspergillosis is waterborne. Clin Infect Dis 2001; 33: 1546-1548.
18. Hajjeh RA, Warnock DW. Counterpoint: Invasive aspergillosis and the environment - rethinking our approach to prevention. Clin Infect Dis 2001; 33: 1549-1552.
19. Weber DJ, Rutala WA. Epidemiology of hospital-acquired fungal infection. In: Holmberg K, Meyer RD (eds). Diagnosis and Therapy of Systemic Fungal Infections. New York: Raven Press, 1989: 1-24.
20. Vonberg R-P, Gastmeier P. Nosocomial aspergillosis in outbreak settings. J Hosp Infect 2006; 63: 246-254.
21. Pittet D, Huguenin T, Dharan S, et al. Unusual cause of lethal pulmonary aspergillosis in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1996; 154: 541-544.
22. Rodrigo N, Perera KNT, Ranwala R, Jayasinghe S, Warnakulasuriya A, Hapuarachchi S. Aspergillus meningitis following spinal anesthesia for caesarian section in Colombo, Sri Lanka. Intern J Obstet Anesthesia 2007; 16: 256-260.
23. Gunaratne PS, Wijeyaratne CN, Seneviratne HR. Aspergillus meningitis in Sri Lanka - a post-tsunami effect. New Engl J Med 2007; 336: 754-756.
24. Panackal AA, Imhof A, Hanley EW, Marr KA. Aspergillus ustus infections among transplant recipients. Emerg Infect Dis 2006; 12: 403-408.
25. Raviv Y, Kramer MR, Amital A, Rubinovitch B, Bishara J, Shitrit D. Outbreak of aspergillosis infections among lung transplant recipients. Transp Intern 2007; 20: 135-140.
26. Saracli MA, Mutlu FM, Yildiran ST, et al. Clustering of invasive Aspergillus ustus eye infections in a tertiary care hospital: A molecular epidemiologic study of an uncommon species. Med Mycol 2007; 45: 377-384.
27. Kronman MP, Baden HP, Jeffries HE, Heath J, Cohen GA, Zerr DM. An investigation of Aspergillus cardiac surgical site infections in 3 pediatric patients. Am J Infect Control 2007; 35: 332-337.
28. Larkin JA, Greene JN, Sandin Rl, Houston SH. Primary cutaneous aspergillosis: Case report and review of the literature. Infect Control Hosp Epidemiol 1996; 17: 365-366.
29. Pasquolotto AC, Denning DW. Post-operative aspergillosis. Clin Microbiol Infect 2006; 12: 1060-1076.
30. Gage AA, Dean DC, Schimert G, Minsley N. Aspergillus infection after cardiac surgery. Arch Surg 1970; 101: 384-387.
31. Kyriakides GK, Zinneman HH, Hall WH, et al. Immunologic monitoring and aspergillosis in renal transplant patients. Am J Surg 1976; 131: 246-252.
32. Mehta G. Aspergillus endocarditis after open heart surgery: An epidemiologic investigation. J Hosp Infect 1990; 15: 245-253.
33. Sarubbi FA, Kopf HB, Wilson MB, McGinnis MR, Rutala WA. Increased recovery of Aspergillus flavus from respiratory specimens during hospital construction. Am Rev Respir Dis 1982; 125: 33-38.
34. Lentino JR, Rosenkranz MA, Michaels JA, Kurup VP, Rose HD, Rytel MW. Nosocomial aspergillosis: A retrospective review of airborne disease secondary to road construction and contaminated air conditioners. Am J Epidemiol 1982; 116: 430-437.
35. del Palacio Hernanz A, Fereres J, Larregla Garraus S, Rodriguez-Noriega A, Sanz Sanz F. Nosocomial infection by Rhizomucor pusillus in a clinical haematology unit. J Hosp Infect 1983; 4: 45-49.
36. Arnow PM, Andersen RL, Mainous PD, Smith EJ. Pulmonary aspergillosis during hospital renovation. Am Rev Resp Dis 1978; 118: 49-53.
37. Opal SM, Asp AA, Cannady PB, Morse PL, Burton LJ, Hammer PG 2nd. Efficacy of infection control measures during a nosocomial outbreak of aspergillosis associated with hospital construction. J Infect Dis 1986; 153: 634-637.
38. Hopkins CC, Weber DJ, Rubin RH. Invasive Aspergillus infection. Possible non-ward common source within the hospital environment. J Hosp Infect 1989; 13: 19-25.
39. Flynn PM,Williams BG, Hetherington SV,Williams BF, Giannini MA, Pearson TA. Aspergillus terreus during hospital renovation. Infect Control Hosp Epidemiol 1993; 14: 363-365.
40. Loo VG, Bertrand C, Dixon C, et al. Control of constructionassociated nosocomial aspergillosis in an antiquated hematology unit. Infect Control Hosp Epidemiol 1996; 17: 360-366.
41. Gaspar C, Mariano A, Cuesta J, et al. Outbreak of invasive pulmonary mycosis in neutropenic hematologic patients in relation to remodeling construction work. Enferm Infecc Microbiol Clin 1999; 17: 113-118.
42. Tabbara KF, Jabarti AA. Hospital construction-associated outbreak of ocular aspergillosis after cataract surgery. Ophthalmol 1998; 105: 522-526.
43. Thio CL, Smith D, MerzWG, et al. Refinements of environmental assessment during an outbreak investigation of invasive aspergillosis in a leukemia and bone marrow transplant unit. Infect Control Hosp Epidemiol 2000; 21: 18-23.
44. Oren I, Haddad N, Finkelstein R, Rowe JM. Invasive pulmonary aspergillosis in neutropenic patients during hospital construction: before and after chemoprophylaxis and institution of HEPA filters. Am J Hematol 2001; 66: 257-262.
45. Burwen DR, Lasker BA, Rao N, et al. Invasive aspergillosis outbreak on a hematology-oncology ward. Infect Control Hosp Epidemiol 2001; 22: 45-48.
46. Lutz BD, Jin J, Rinaldi MG, Wickes BL, Huycke MM. Outbreak of Aspergillus infection in surgical patients, associated with a contaminated air-handling system. Clin Infect Dis 2003; 37: 786-793.
47. Bryce EA, Walker M, Scharf S, et al. An outbreak of cutaneous aspergillosis in a tertiary-care hospital. Infect Control Hosp Epidemiol 1996; 17: 170-172.
48. Singer S, Singer D, Ruchel R, Mergeryan H, Schmidt U, Harms K. Outbreak of aspergillosis in a neonatal intensive care unit. Mycoses 1998; 41: 223-227.
49. Vandercasteele SJ, Boelaert JR, Verrelst P, Graulus E, Gordts BZ. Diagnosis and treatment of Aspergillus flavus sternal wound infections after cardiac surgery. Clin Infect Dis 2002; 35: 887-890.
50. Humphreys H, Johnson EM, Warnock DW, Williatts SM, Winter RJ, Speller DCE. An outbreak of aspergillosis in a general ITU. J Hosp Infect 1991; 18: 167-177.
51. Grossman ME, Fithian EC, Behrens C, Bissinger J, Fracaro M, Neu HC. Primary cutaneous aspergillosis in six leukemic children. J Am Acad Dermatol 1985; 12: 313-318.
52. Birch M, Anderson MJ, Denning DW. Molecular typing of Aspergillus species. J Hosp Infect 1995; 30 (Suppl.): 339-351.
53. Lasker BA. Evaluation performance of four genotypic methods for studying the genetic epidemiology of Aspergillus fumigatus isolates. J Clin Microbiol 2002; 40: 2886-2892.
54. Chazalet V, Debeaupuis J-P, Sarfati J, et al. Molecular typing of environmental and patient isolates of Aspergillus fumigatus from various hospital settings. J Clin Microbiol 1998; 36: 1494-1500.
55. Menotti J, Waller J, Meunier O, Letscher-Bru V, Herbrecht R, Candolfi E. Epidemiological study of invasive pulmonary aspergillosis in a haematology unit by molecular typing of environmental and patient isolates of Aspergillus fumigatus. J Hosp Infect 2005; 60 61-68.
56. Heinemann S, Symoens F, Gordts B, Jannes H, Nolard N. Environmental investigations and molecular typing of Aspergillus flavus during an outbreak of postoperative infections. J Hosp Infect 2004; 57 149-155.
57. Leenders A, van Belkum A, Janssen S, et al. Molecular epidemiology of apparent outbreak of invasive aspergillosis in a hematology ward. J Clin Microbiol 1996; 34: 345-351.
58. Weems JJ Jr, Andremont A, Davis BJ, et al. Pseudoepidemic of aspergillosis after development of pulmonary infiltrates in a group of bone marrow transplant patients. J Clin Microbiol 1987; 25: 1459-1462.
59. Laurel VL, Meier PA, Astorga A, Dolan D, Brockett R, Rinaldi MG. Pseudoepidemic of Aspergillus niger infections traced to specimen contamination in the microbiology laboratory. J Clin Microbiol 1999; 37: 1612-1616.
60. Freeman J, Rogers K, Roberts S. Pseudo-outbreak of Aspergillus keratitis following construction in an ophthalmology ward. J Hosp Infect 2007; 67: 104-105.
61. Centers for Disease Control and Prevention. Guidelines for preventing opportunistic infections among hematopoietic stem cell transplant recipients. Recommendations of CDC, the Infectious Disease Society of America, and the American Society of Blood and Marrow Transplantation. MMWR 2000; 49 (RR-10): 1-126.
62. Centers for Disease Control and Prevention. Guidelines for preventing healthcare-associated pneumonia, 2003. Recommendations of CDC and Healthcare Infection Control Practices Advisory Committee. Accessed 28 January 2003 from: http://www.cdc.gov/ncidod/dhqp/gl_hcpneumonia.html
63. Centers for Disease Control and Prevention. Guidelines for environmental infection control in healthcare facilities (2003). Recommendations of CDC and Healthcare Infection Control Practices Advisory Committee (HICPAC). Accessed 28 January 2008 from: http://www.cdc.gov/ncidod/dhqp/ gl_environinfection.html
64. Centers for Disease Control and Prevention. Guideline for isolation precautions: Preventing transmission of infectious agents in healthcare settings, 2007. Accessed 28 January 2008 from: http://cdc.gov/ncidod/ dhqp/gl_caolation.html
65. Division of Nosocomial and Occupational Infections, Bureau of Infectious Diseases, Centre for Infectious Disease Prevention and Control Population and Public Health Branch, Health Canada. Construction-related nosocomial infections in patients in health care facilities: Decreasing the risk of Aspergillus, Legionella and other infections. CCDR 2001l2752.
66. American Institute of Architects and Academy of Architecture for Health. Guidelines for Design and Construction of Health Care Facilities. Washington DC, American Institute for Architects, 2006.
67. Walsh TJ, Anaissie EJ, Denning DW, et al. Treatment of aspergillosis: Clinical practice guidelines of the Infectious Disease Society of America. Clin Infect Dis 2008; 46: 327-360.