Community-associated meticillin-resistant Staphylococcus aureus: epidemiology, microbiology and clinical impact in East Yorkshire, UK

Journal of Hospital Infection

Volumn 72, Issue 4, 2009, Pages 307-313

  Elston, J W T ^a   Meigh, J ^b   Kearns, A M ^c   Jordan Owers, N ^b   Newton, A ^d   Meigh, R E ^b   Barlow, G ^a  

^a CASTLE HILL HOSPITAL   (United Kingdom)

^b HULL ROYAL INFIRMARY   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d Humber Health Protection Unit   (United Kingdom)

Author keywords

Clinical impact; Community associated; Epidemiology; Meticillin resistant Staphylococcus aureus; Panton Valentine leucocidin

Indexed keywords

CIPROFLOXACIN; CLARITHROMYCIN; FUSIDIC ACID; PANTON VALENTINE LEUKOCIDIN; RIFAMPICIN; TETRACYCLINE; TRIMETHOPRIM; VANCOMYCIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CHILD; CLINICAL ARTICLE; COMMUNITY CARE; DISEASE ASSOCIATION; DISEASE SEVERITY; FATALITY; FEMALE; HUMAN; INFANT; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; NONHUMAN; PREVALENCE; RETROSPECTIVE STUDY; SKIN INFECTION; SOFT TISSUE INFECTION; UNITED KINGDOM;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTERIAL TYPING TECHNIQUES; CHILD; CHILD, PRESCHOOL; CLUSTER ANALYSIS; COMMUNITY-ACQUIRED INFECTIONS; DNA FINGERPRINTING; DNA, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; EPIDEMIOLOGY, MOLECULAR; FEMALE; GENOTYPE; GREAT BRITAIN; HUMANS; INFANT; INFANT, NEWBORN; MALE; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MIDDLE AGED; STAPHYLOCOCCAL INFECTIONS; YOUNG ADULT;

EID: 67651089637     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2009.05.001     Document Type: Article

References (22)

1. Zetola N., Francis J.S., Nuermberger E.L., and Bishai W.R. Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis 5 (2005) 275-286
2. Vandenesch F., Naimi T., Enright M.C., et al. Community-acquired methicillin-resistant Staphylococcus aureus carrying Panton-Valentine leukocidin genes: worldwide emergence. Emerg Infect Dis 9 (2003) 978-984
3. Fridkin S.K., Hageman J.C., Morrison M., et al. Methicillin-resistant Staphylococcus aureus disease in three communities. N Engl J Med 352 (2005) 1436-1444
4. Francis J.S., Doherty M.C., Lopatin U., et al. Severe community-onset pneumonia in healthy adults caused by methicillin-resistant Staphylococcus aureus carrying the Panton-Valentine leukocidin genes. Clin Infect Dis 40 (2005) 100-107
5. Health Protection Agency. Hospital-associated transmission of Panton-Valentine leukocidin (PVL) positive community-associated MRSA in the West Midlands. CDR Wkly 16 (2006) 50
6. David M.D., Kearns A.M., Gossain S., Ganner M., and Holmes A. Community-associated methicillin-resistant Staphylococcus aureus: nosocomial transmission in a neonatal unit. J Hosp Infect 64 (2006) 244-250
7. Otter J.A., and French G.L. Nosocomial transmission of community-associated methicillin-resistant Staphylococcus aureus: an emerging threat. Lancet Infect Dis 6 (2006) 753-755
8. Tacconelli E., Venkataraman L., De Girolami P.C., and D'Agata E.M. Methicillin-resistant Staphylococcus aureus bacteraemia diagnosed at hospital admission: distinguishing between community-acquired versus healthcare associated strains. J Antimicrob Chemother 53 (2004) 474-479
9. Nathwani D., Morgan M., Masterton R.G., et al. Guidelines for UK practice for the diagnosis and management of methicillin-resistant Staphylococcus aureus (MRSA) infections presenting in the community. J Antimicrob Chemother 61 (2008) 976-994
10. Miller L.G., Perdreau-Remington F., Bayer A.S., et al. Clinical and epidemiologic characteristics cannot distinguish community-associated methicillin-resistant Staphylococcus aureus from methicillin-susceptible S. aureus infection: a prospective investigation. Clin Infect Dis 44 (2007) 471-482
11. Millar B.C., Loughrey A., Elborn J.S., and Moore J.E. Proposed definitions of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA). J Hosp Infect 67 (2007) 109-113
12. Moran G.J., Krishnadasan A., Gorwitz R.J., et al. Methicillin-resistant Staphylococcus aureus infections among patients in the emergency department. N Engl J Med 355 (2006) 666-674
13. Frazee B.W., Lynn J., Charlebois E.D., et al. High prevelance of methicillin-resistant Staphylococcus aureus in emergency department skin and soft tissue infections. Ann Emerg Med 45 (2005) 311-320
14. King M.D., Humphrey B.J., Wang Y.F., Kourbatova E.V., Ray S.M., and Blumberg H.M. Emergence of community-acquired methicillin-resistant Staphylococcus aureus USA300 clone as the predominant cause of skin and soft tissue infections. Ann Intern Med 144 (2006) 309-317
15. Otter J.A., and French G.L. The emergence of community-associated methicillin-resistant Staphylococcus aureus at a London teaching hospital, 2000-2006. Clin Microbiol Infect 14 (2008) 670-676
16. Holmes A., Ganner M., McGuane S., Pitt T.L., Cookson B.D., and Kearns A.M. Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterization, and association with clinical disease. J Clin Microbiol 43 (2005) 2384-2390
17. Health Protection Agency. Community MRSA in England and Wales: definition through strain characterization. CDR Wkly 15 (2005) 11
18. Health Protection Agency. Susceptibility testing. National Standard Method BSOP 45 Issue 2. 2006.
19. Health Protection Agency. Identification of Staphylococcus species, Micrococcus species and Rothia species. National Standard Method BSOP ID 7 Issue 2.1. 2007.
20. Health Protection Agency. Guidance on the diagnosis and management of PVL-associated Staphylococcus aureus infections (PVL-SA) in England, 2nd Edition. 2008.
21. Johnson A.P., Auken H.M., Cavendish S., et al. Dominance of EMRSA-15 and -16 among MRSA causing nosocomial bacteraemia in the UK: analysis of isolates from the European Antimicrobial Resistance Surveillance System (EARSS). J Antimicrob Chemother 48 (2001) 143-144
22. Hill RLR, Kearns AM, Pike R, et al. Does ciprofloxacin susceptibility provide a reliable phenotypic marker for community-associated MRSA? Poster presentation at 46th ICAAC, San Francisco, September 2006.