Curcumin improves vascular function and alleviates oxidative stress in non-lethal lipopolysaccharide-induced endotoxaemia in mice

European Journal of Pharmacology

Volumn 616, Issue 1-3, 2009, Pages 192-199

  Sompamit, Kwanjit ^a   Kukongviriyapan, Upa ^a   Nakmareong, Saowanee ^a   Pannangpetch, Patchareewan ^a   Kukongviriyapan, Veerapol ^a  

^a KHON KAEN UNIVERSITY   (Thailand)

Author keywords

Antioxidant; Curcumin; Lipopolysaccharide; Oxidative stress; Vascular dysfunction

Indexed keywords

ACETYLCHOLINE; CURCUMIN; GLUTATHIONE; GLUTATHIONE DISULFIDE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; SUPEROXIDE; VASOACTIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL FUNCTION; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; ENDOTOXEMIA; HEART RATE; HEMODYNAMICS; HYPOTENSION; INSTITUTE FOR CANCER RESEARCH MOUSE; LIPID PEROXIDATION; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; TACHYCARDIA; VASCULAR DISEASE;

ANIMALS; ANTIOXIDANTS; BLOOD VESSELS; CURCUMIN; ENDOTOXEMIA; HEMODYNAMICS; LIPOPOLYSACCHARIDES; MALE; MICE; MICE, INBRED ICR; OXIDANTS; OXIDATIVE STRESS;

EID: 67651085556     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2009.06.014     Document Type: Article

References (49)

1. Aggarwal B.B., Sundaram C., Malani N., and Ichikawa H. Curcumin: the Indian solid gold. Adv. Exp. Med. Biol. 595 (2007) 1-75
2. Ammon H.P., and Wahl M.A. Pharmacology of Curcuma longa. Planta Med. 57 (1991) 1-7
3. Anrather J., Racchumi G., and Iadecola C. NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J. Biol. Chem. 281 (2006) 5657-5667
4. Beasley D., Schwartz J.H., and Brenner B.M. Interleukin 1 induces prolonged L-arginine-dependent cyclic guanosine monophosphate and nitrite production in rat vascular smooth muscle cells. J. Clin. Invest. 87 (1991) 602-608
5. Begum A.N., Jones M.R., Lim G.P., Morihara T., Kim P., Heath D.D., Rock C.L., Pruitt M.A., Yang F., Hudspeth B., Hu S., Faull K.F., Teter B., Cole G.M., and Frautschy S.A. Curcumin structure-function, bioavailability, and efficacy in models of neuroinflammation and Alzheimer's disease. J. Pharmacol. Exp. Ther. 326 (2008) 196-208
6. Bengmark S. Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseases. JPEN J. Parenter. Enteral Nutr. 30 (2006) 45-51
7. Brandes R.P., Koddenberg G., Gwinner W., Kim D., Kruse H.J., Busse R., and Mugge A. Role of increased production of superoxide anions by NAD(P)H oxidase and xanthine oxidase in prolonged endotoxemia. Hypertension 33 (1999) 1243-1249
8. Cai H., and Harrison D.G. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ. Res. 87 (2000) 840-844
9. Cena J., Lalu M.M., Rosenfelt C., and Schulz R. Endothelial dependence of matrix metalloproteinase-mediated vascular hyporeactivity caused by lipopolysaccharide. Eur. J. Pharmacol. 582 (2008) 116-122
10. Chan M.M., Ho C.T., and Huang H.I. Effects of three dietary phytochemicals from tea, rosemary and turmeric on inflammation-induced nitrite production. Cancer Lett. 96 (1995) 23-29
11. Chauhan S.D., Seggara G., Vo P.A., Macallister R.J., Hobbs A.J., and Ahluwalia A. Protection against lipopolysaccharide-induced endothelial dysfunction in resistance and conduit vasculature of iNOS knockout mice. Faseb. J. 17 (2003) 773-775
12. Chen H.W., Kuo H.T., Chai C.Y., Ou J.L., and Yang R.C. Pretreatment of curcumin attenuates coagulopathy and renal injury in LPS-induced endotoxemia. J. Endotoxin. Res. 13 (2007) 15-23
13. Cuzzocrea S., Mazzon E., Di Paola R., Esposito E., Macarthur H., Matuschak G.M., and Salvemini D. A role for nitric oxide-mediated peroxynitrite formation in a model of endotoxin-induced shock. J. Pharmacol. Exp. Ther. 319 (2006) 73-81
14. Hom G.J., Grant S.K., Wolfe G., Bach T.J., MacIntyre D.E., and Hutchinson N.I. Lipopolysaccharide-induced hypotension and vascular hyporeactivity in the rat: tissue analysis of nitric oxide synthase mRNA and protein expression in the presence and absence of dexamethasone, NG-monomethyl-L-arginine or indomethacin. J. Pharmacol. Exp. Ther. 272 (1995) 452-459
15. Ireson C.R., Jones D.J., Orr S., Coughtrie M.W., Boocock D.J., Williams M.L., Farmer P.B., Steward W.P., and Gescher A.J. Metabolism of the cancer chemopreventive agent curcumin in human and rat intestine. Cancer Epidemiol. Biomark. Prev. 11 (2002) 105-111
16. Jiang J., Wang W., Sun Y.J., Hu M., Li F., and Zhu D.Y. Neuroprotective effect of curcumin on focal cerebral ischemic rats by preventing blood-brain barrier damage. Eur. J. Pharmacol. 561 (2007) 54-62
17. Julou-Schaeffer G., Gray G.A., Fleming I., Schott C., Parratt J.R., and Stoclet J.C. Loss of vascular responsiveness induced by endotoxin involves L-arginine pathway. Am. J. Physiol. 259 (1990) H1038-1043
18. Karimi G., Fatehi Z., and Gholamnejad Z. The role of nitric oxide and protein kinase C in lipopolysaccharidemediated vascular hyporeactivity. J. Pharm. Sci. 9 (2006) 119-123
19. Kaur G., Tirkey N., Bharrhan S., Chanana V., Rishi P., and Chopra K. Inhibition of oxidative stress and cytokine activity by curcumin in amelioration of endotoxin-induced experimental hepatoxicity in rodents. Clin. Exp. Immunol. 145 (2006) 313-321
20. Kukongviriyapan V., Somparn N., Senggunprai L., Prawan A., Kukongviriyapan U., and Jetsrisuparb A. Endothelial dysfunction and oxidant status in pediatric patients with hemoglobin E-beta thalassemia. Pediatr. Cardiol. 29 (2008) 130-135
21. Lee C.C., Lin N.T., Hsu Y.H., and Chen H.I. Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats. J. Cardiovasc. Pharmacol. 45 (2005) 396-403
22. Lin J.K. Molecular targets of curcumin. Adv. Exp. Med. Biol. 595 (2007) 227-243
23. Lu J.L., Schmiege III L.M., Kuo L., and Liao J.C. Downregulation of endothelial constitutive nitric oxide synthase expression by lipopolysaccharide. Biochem. Biophys. Res. Commun. 225 (1996) 1-5
24. Luangaram S., Kukongviriyapan U., Pakdeechote P., Kukongviriyapan V., and Pannangpetch P. Protective effects of quercetin against phenylhydrazine-induced vascular dysfunction and oxidative stress in rats. Food Chem. Toxicol. 45 (2007) 448-455
25. Lukita-Atmadja W., Ito Y., Baker G.L., and McCuskey R.S. Effect of curcuminoids as anti-inflammatory agents on the hepatic microvascular response to endotoxin. Shock 17 (2002) 399-403
26. Madan B., and Ghosh B. Diferuloylmethane inhibits neutrophil infiltration and improves survival of mice in high-dose endotoxin shock. Shock 19 (2003) 91-96
27. Maheshwari R.K., Singh A.K., Gaddipati J., and Srimal R.C. Multiple biological activities of curcumin: a short review. Life Sci. 78 (2006) 2081-2087
28. Memis D., Hekimoglu S., Sezer A., Altaner S., Sut N., and Usta U. Curcumin attenuates the organ dysfunction caused by endotoxemia in the rat. Nutrition 24 (2008) 1133-1138
29. Meziani F., Kremer H., Tesse A., Baron-Menguy C., Mathien C., Mostefai H.A., Carusio N., Schneider F., Asfar P., and Andriantsitohaina R. Human serum albumin improves arterial dysfunction during early resuscitation in mouse endotoxic model via reduced oxidative and nitrosative stresses. Am. J. Pathol. 171 (2007) 1753-1761
30. Miles A.M., Bohle D.S., Glassbrenner P.A., Hansert B., Wink D.A., and Grisham M.B. Modulation of superoxide-dependent oxidation and hydroxylation reactions by nitric oxide. J. Biol. Chem. 271 (1996) 40-47
31. Myers P.R., Zhong Q., Jones J.J., Tanner M.A., Adams H.R., and Parker J.L. Release of EDRF and NO in ex vivo perfused aorta: inhibition by in vivo E. coli endotoxemia. Am. J. Physiol. 268 (1995) H955-961
32. Nirmala C., Anand S., and Puvanakrishnan R. Curcumin treatment modulates collagen metabolism in isoproterenol induced myocardial necrosis in rats. Mol. Cell. Biochem. 197 (1999) 31-37
33. Papapetropoulos A., Abou-Mohamed G., Marczin N., Murad F., Caldwell R.W., and Catravas J.D. Downregulation of nitrovasodilator-induced cyclic GMP accumulation in cells exposed to endotoxin or interleukin-1 beta. Br. J. Pharmacol. 118 (1996) 1359-1366
34. Piepot H.A., Groeneveld A.B., van Lambalgen A.A., and Sipkema P. Endotoxin impairs endothelium-dependent vasodilation more in the coronary and renal arteries than in other arteries of the rat. J. Surg. Res. 110 (2003) 413-418
35. Rahman I., Biswas S.K., and Kirkham P.A. Regulation of inflammation and redox signaling by dietary polyphenols. Biochem. Pharmacol. 72 (2006) 1439-1452
36. Ralay Ranaivo H., Carusio N., Wangensteen R., Ohlmann P., Loichot C., Tesse A., Chalupsky K., Lobysheva I., Haiech J., Watterson D.M., and Andriantsitohaina R. Protection against endotoxic shock as a consequence of reduced nitrosative stress in MLCK210-null mice. Am. J. Pathol. 170 (2007) 439-446
37. Rees D.D. Role of nitric oxide in the vascular dysfunction of septic shock. Biochem. Soc. Trans. 23 (1995) 1025-1029
38. Reznick A.Z., and Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol. 233 (1994) 357-363
39. Sharma R.A., Gescher A.J., and Steward W.P. Curcumin: the story so far. Eur. J. Cancer 41 (2005) 1955-1968
40. Shoba G., Joy D., Joseph T., Majeed M., Rajendran R., and Srinivas P.S. Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Med. 64 (1998) 353-356
41. Siegel J.H., Greenspan M., and Del Guercio L.R. Abnormal vascular tone, defective oxygen transport and myocardial failure in human septic shock. Ann. Surg. 165 (1967) 504-517
42. Somparn N., Kukongviriyapan U., Tassaneeyakul W., Jetsrisuparb A., and Kukongviriyapan V. Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients. Eur. J. Clin. Pharmacol. 63 (2007) 43-50
43. Surh Y.J. Cancer chemoprevention with dietary phytochemicals. Nat. Rev. Cancer. 3 (2003) 768-780
44. Tatsumi T., Akashi K., Keira N., Matoba S., Mano A., Shiraishi J., Yamanaka S., Kobara M., Hibino N., Hosokawa S., Asayama J., Fushiki S., Fliss H., Nakagawa M., and Matsubara H. Cytokine-induced nitric oxide inhibits mitochondrial energy production and induces myocardial dysfunction in endotoxin-treated rat hearts. J. Mol. Cell. Cardiol. 37 (2004) 775-784
45. Thimmulappa R.K., Lee H., Rangasamy T., Reddy S.P., Yamamoto M., Kensler T.W., and Biswal S. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis. J. Clin. Invest. 116 (2006) 984-995
46. Victor V.M., and De la Fuente M. Immune cells redox state from mice with endotoxin-induced oxidative stress. Involvement of NF-kappaB. Free Radic. Res. 37 (2003) 19-27
47. Victor V.M., Rocha M., and De la Fuente M. N-acetylcysteine protects mice from lethal endotoxemia by regulating the redox state of immune cells. Free Radic. Res. 37 (2003) 919-929
48. Wanecek M., Weitzberg E., Rudehill A., and Oldner A. The endothelin system in septic and endotoxin shock. Eur. J. Pharmacol. 407 (2000) 1-15
49. Zingarelli B., Day B.J., Crapo J.D., Salzman A.L., and Szabo C. The potential role of peroxynitrite in the vascular contractile and cellular energetic failure in endotoxic shock. Br. J. Pharmacol. 120 (1997) 259-267