메뉴 건너뛰기




Volumn 6, Issue 1, 2009, Pages 103-113

TPMT testing in azathioprine: A 'cost-effective use of healthcare resources'?

Author keywords

Azathioprine; Cost effectiveness analysis; Economic evaluation; Imuran; Leucopenia; Mercaptopurines; Neutropenia; Pharmacogeneticsthiopurine S methyltransferase; Value of information

Indexed keywords

AZATHIOPRINE; THIOPURINE METHYLTRANSFERASE;

EID: 67651083364     PISSN: 17410541     EISSN: 1744828X     Source Type: Journal    
DOI: 10.2217/17410541.6.1.103     Document Type: Article
Times cited : (25)

References (28)
  • 1
    • 37349033669 scopus 로고    scopus 로고
    • Drug reactions, enzymes, and biochemical genetics': 50 years later
    • Gurwitz D, Motulsky AG: 'Drug reactions, enzymes, and biochemical genetics': 50 years later. Pharmacogenomics 8(11), 1479-1484 (2007).
    • (2007) Pharmacogenomics , vol.8 , Issue.11 , pp. 1479-1484
    • Gurwitz, D.1    Motulsky, A.G.2
  • 2
    • 33947357078 scopus 로고    scopus 로고
    • Current use of pharmacogenetic testing: A national survey of thiopurine methyltransferase (TPMT) testing prior to azathioprine prescription
    • Fargher EA, Tricker K, Newman W et al.: Current use of pharmacogenetic testing: a national survey of thiopurine methyltransferase (TPMT) testing prior to azathioprine prescription. J. Clin. Pharm. Ther. 32, 187-195 (2007).
    • (2007) J. Clin. Pharm. Ther , vol.32 , pp. 187-195
    • Fargher, E.A.1    Tricker, K.2    Newman, W.3
  • 3
    • 31044434278 scopus 로고    scopus 로고
    • The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies
    • Woelderlink, A Ibarreta D, Hopkins M, Rodriguez-Cerezo E: The current clinical practice of pharmacogenetic testing in Europe: TPMT and HER2 as case studies. Pharmacogenomics J. 6(1), 3-7 (2006)
    • (2006) Pharmacogenomics J , vol.6 , Issue.1 , pp. 3-7
    • Woelderlink, A.1    Ibarreta, D.2    Hopkins, M.3    Rodriguez-Cerezo, E.4
  • 4
    • 3242704015 scopus 로고    scopus 로고
    • Thiopurine methyltransferase: Should it be measured before commencing thiopurine drug therapy?
    • Sanderson J, Ansari A, Marinaki T, Duley J: Thiopurine methyltransferase: should it be measured before commencing thiopurine drug therapy? Ann. Clin. Biochem. 41, 294-302 (2004).
    • (2004) Ann. Clin. Biochem , vol.41 , pp. 294-302
    • Sanderson, J.1    Ansari, A.2    Marinaki, T.3    Duley, J.4
  • 5
    • 33645119580 scopus 로고    scopus 로고
    • Thiopurine S-methyltransferase pharmacogenetics: Insights, challenges and future directions
    • Wang L, Weinshilboum R: Thiopurine S-methyltransferase pharmacogenetics: insights, challenges and future directions. Oncogene 25(11), 1629-1638 (2006).
    • (2006) Oncogene , vol.25 , Issue.11 , pp. 1629-1638
    • Wang, L.1    Weinshilboum, R.2
  • 6
    • 0030934850 scopus 로고    scopus 로고
    • Molecular diagnosis of thiopurine-S- methyltransferase deficiency: Genetic basis for azathioprine and mercaptopurine intolerance
    • Yates CR, Krynetski EY, Loennechen T et al.: Molecular diagnosis of thiopurine-S- methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance. Ann. Intern. Med. 126, 608-616 (1997).
    • (1997) Ann. Intern. Med , vol.126 , pp. 608-616
    • Yates, C.R.1    Krynetski, E.Y.2    Loennechen, T.3
  • 7
    • 34247159530 scopus 로고    scopus 로고
    • Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease
    • Winter JW, Gaffney D, Shapiro D et al.: Assessment of thiopurine methyltransferase enzyme activity is superior to genotype in predicting myelosuppression following azathioprine therapy in patients with inflammatory bowel disease. Aliment Pharmacol. Ther. 25, 1069-1077 (2007).
    • (2007) Aliment Pharmacol. Ther , vol.25 , pp. 1069-1077
    • Winter, J.W.1    Gaffney, D.2    Shapiro, D.3
  • 8
    • 46749126229 scopus 로고    scopus 로고
    • Avoiding adverse drug reactions by pharmacogenetic testing: A systematic review of the economic evidence in the case of TPMT and AZA-induced side effects
    • Compagni A, Bartoli S, Buehrlen B, Fattore G, Ibarreta D, Gutierrez de Mesa E: Avoiding adverse drug reactions by pharmacogenetic testing: a systematic review of the economic evidence in the case of TPMT and AZA-induced side effects. Int. J. Tech. Assess. Health Care 24(3), 294-302 (2008).
    • (2008) Int. J. Tech. Assess. Health Care , vol.24 , Issue.3 , pp. 294-302
    • Compagni, A.1    Bartoli, S.2    Buehrlen, B.3    Fattore, G.4    Ibarreta, D.5    Gutierrez de Mesa, E.6
  • 9
    • 45749090093 scopus 로고    scopus 로고
    • Pharmacoeconomic evaluations of pharmacogenetic and genomic screening programmes. A systematic review on content and adherence to guidelines
    • Vegter S, Boersma C, Rozenbaum M et al.: Pharmacoeconomic evaluations of pharmacogenetic and genomic screening programmes. A systematic review on content and adherence to guidelines. Pharmacoeconomics 26(7), 569-587 (2008).
    • (2008) Pharmacoeconomics , vol.26 , Issue.7 , pp. 569-587
    • Vegter, S.1    Boersma, C.2    Rozenbaum, M.3
  • 11
    • 27744574836 scopus 로고    scopus 로고
    • A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine
    • Dubinsky MC, Reyes E, Ofman J, Chiou CF, Wade S, Sandborn WJ: A cost-effectiveness analysis of alternative disease management strategies in patients with Crohn's disease treated with azathioprine or 6-mercaptopurine. Am. J. Gastroenterol. 100(10), 2239-2247 (2005).
    • (2005) Am. J. Gastroenterol , vol.100 , Issue.10 , pp. 2239-2247
    • Dubinsky, M.C.1    Reyes, E.2    Ofman, J.3    Chiou, C.F.4    Wade, S.5    Sandborn, W.J.6
  • 12
    • 0036894866 scopus 로고    scopus 로고
    • Practical pharmacogenetics: The cost effectiveness of screening for thiopurine S-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprine
    • Marra CA, Esdaile JM, Anis AH: Practical pharmacogenetics: the cost effectiveness of screening for thiopurine S-methyltransferase polymorphisms in patients with rheumatological conditions treated with azathioprine. J. Rheumatol. 29(12), 2507-2512 (2002).
    • (2002) J. Rheumatol , vol.29 , Issue.12 , pp. 2507-2512
    • Marra, C.A.1    Esdaile, J.M.2    Anis, A.H.3
  • 13
    • 1242297064 scopus 로고    scopus 로고
    • Pharmacoeconomic analysis of thiopurine methyltransferase polymorphism screening by polymerase chain reaction for treatment with azathioprine in Korea
    • Oh KT, Anis AH, Bae SC: Pharmacoeconomic analysis of thiopurine methyltransferase polymorphism screening by polymerase chain reaction for treatment with azathioprine in Korea. Rheumatology 43(2), 156-163 (2004).
    • (2004) Rheumatology , vol.43 , Issue.2 , pp. 156-163
    • Oh, K.T.1    Anis, A.H.2    Bae, S.C.3
  • 14
    • 33747167334 scopus 로고    scopus 로고
    • Pharmacoeconomic analyses of azathioprine, methotrexare and prospective pharmacogenetic testing for the management of inflammatory bowel disease
    • Priest VL, Begg EJ, Gardiner SJ et al.: Pharmacoeconomic analyses of azathioprine, methotrexare and prospective pharmacogenetic testing for the management of inflammatory bowel disease. Pharmacoeconomics 24(8), 767-781 (2006).
    • (2006) Pharmacoeconomics , vol.24 , Issue.8 , pp. 767-781
    • Priest, V.L.1    Begg, E.J.2    Gardiner, S.J.3
  • 15
    • 33747168764 scopus 로고    scopus 로고
    • Cost-effectiveness of pharmacogenomics in clinical practice: A case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe
    • van den Akker-van Marle ME, Gurwit z D, Detmar SB et al.: Cost-effectiveness of pharmacogenomics in clinical practice: a case study of thiopurine methyltransferase genotyping in acute lymphoblastic leukemia in Europe. Pharmacogenomics 7(5), 783-792 (2006).
    • (2006) Pharmacogenomics , vol.7 , Issue.5 , pp. 783-792
    • van den Akker-van Marle, M.E.1    Gurwit z, D.2    Detmar, S.B.3
  • 16
    • 4644241129 scopus 로고    scopus 로고
    • Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease
    • Winter J, Walker A, Shapiro D, Gaffney D, Spooner RJ, Mills PR: Cost-effectiveness of thiopurine methyltransferase genotype screening in patients about to commence azathioprine therapy for treatment of inflammatory bowel disease. Aliment. Pharmacol. Ther. 20(6), 593-599 (2004).
    • (2004) Aliment. Pharmacol. Ther , vol.20 , Issue.6 , pp. 593-599
    • Winter, J.1    Walker, A.2    Shapiro, D.3    Gaffney, D.4    Spooner, R.J.5    Mills, P.R.6
  • 17
    • 17644381606 scopus 로고    scopus 로고
    • Thiopurine methyltransferase enzyme activity determination before treatment of inflammatory bowel disease with azathioprine: Effect on cost and adverse events
    • Sayani FA, Prosser C, Bailey RJ, Jacobs P, Fedorak RN: Thiopurine methyltransferase enzyme activity determination before treatment of inflammatory bowel disease with azathioprine: effect on cost and adverse events. Can. J. Gastroenterol. 19(3), 147-151 (2005).
    • (2005) Can. J. Gastroenterol , vol.19 , Issue.3 , pp. 147-151
    • Sayani, F.A.1    Prosser, C.2    Bailey, R.J.3    Jacobs, P.4    Fedorak, R.N.5
  • 18
    • 0033941305 scopus 로고    scopus 로고
    • Screening for azathioprine toxicity: A pharmacoeconomic analysis based on a target case
    • Tavadia SMB, Mydlarski PR, Reis MD et al.: Screening for azathioprine toxicity: a pharmacoeconomic analysis based on a target case. J. Am. Acad. Dermatol. 42(4), 628-632 (2000).
    • (2000) J. Am. Acad. Dermatol , vol.42 , Issue.4 , pp. 628-632
    • Tavadia, S.M.B.1    Mydlarski, P.R.2    Reis, M.D.3
  • 19
    • 27944434836 scopus 로고    scopus 로고
    • TPMT genotype screening for patients about to begin azathioprine treatment - a look at costs and potential benefits
    • Provenzale D, Onken JE: TPMT genotype screening for patients about to begin azathioprine treatment - a look at costs and potential benefits. Inflamm. Bowel Dis. 11(12), 1119-1120 (2005).
    • (2005) Inflamm. Bowel Dis , vol.11 , Issue.12 , pp. 1119-1120
    • Provenzale, D.1    Onken, J.E.2
  • 20
    • 33645810425 scopus 로고    scopus 로고
    • Good practice guidelines for decision-analytic modelling in health technology assessment: A review and consolidation of quality of assessment
    • Philips Z, Bojke L, Sculpher M, Claxton K, Golder S: Good practice guidelines for decision-analytic modelling in health technology assessment: a review and consolidation of quality of assessment. Pharmacoeconomics 24, 355-371 (2006).
    • (2006) Pharmacoeconomics , vol.24 , pp. 355-371
    • Philips, Z.1    Bojke, L.2    Sculpher, M.3    Claxton, K.4    Golder, S.5
  • 22
    • 40449092560 scopus 로고    scopus 로고
    • Azathioprine-induced fatal myclosuppression in systemic lupris erythematosus patient carrying TPMT*3C polymorphism
    • Boonsrirat U, Angsuthum S, Vannaprasaht S et al.: Azathioprine-induced fatal myclosuppression in systemic lupris erythematosus patient carrying TPMT*3C polymorphism. Lupus 17, 132-1324 (2008).
    • (2008) Lupus , vol.17 , pp. 132-1324
    • Boonsrirat, U.1    Angsuthum, S.2    Vannaprasaht, S.3
  • 24
    • 0031047648 scopus 로고    scopus 로고
    • The iterative use of economic evaluation as part of the process of health technology assessment
    • Sculpher M, Drummond M, Buxton M: The iterative use of economic evaluation as part of the process of health technology assessment. J. Health Serv. Res. Policy 2(1), 26-30 (1997).
    • (1997) J. Health Serv. Res. Policy , vol.2 , Issue.1 , pp. 26-30
    • Sculpher, M.1    Drummond, M.2    Buxton, M.3
  • 25
    • 52149099443 scopus 로고    scopus 로고
    • Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease
    • Ansari A, Arenas M, Greenfield SM et al.: Prospective evaluation of the pharmacogenetics of azathioprine in the treatment of inflammatory bowel disease. Aliment Pharmacol. Ther. 28(8), 973-983 (2008).
    • (2008) Aliment Pharmacol. Ther , vol.28 , Issue.8 , pp. 973-983
    • Ansari, A.1    Arenas, M.2    Greenfield, S.M.3
  • 26
    • 17144409710 scopus 로고    scopus 로고
    • Probabilistic sensitivity analysis for NICE technology assessment: Not an optional extra
    • Claxton K, Schulpher M, McCabe C et al.: Probabilistic sensitivity analysis for NICE technology assessment: not an optional extra. Health Econ. 14, 339-347 (2005).
    • (2005) Health Econ , vol.14 , pp. 339-347
    • Claxton, K.1    Schulpher, M.2    McCabe, C.3
  • 27
    • 0033044884 scopus 로고    scopus 로고
    • The irrelevance of inference: A decision-making approach to the stochastic evaluation of health care technologies
    • Claxton K: The irrelevance of inference: a decision-making approach to the stochastic evaluation of health care technologies. J Health Econ. 18, 341-364 (1999).
    • (1999) J Health Econ , vol.18 , pp. 341-364
    • Claxton, K.1
  • 28
    • 1642369384 scopus 로고    scopus 로고
    • Expected value of sample information in medical decision modeling
    • Claxton K, Ades AE, Lu G: Expected value of sample information in medical decision modeling. Med. Decis. Making 24, 207-228 (2004).
    • (2004) Med. Decis. Making , vol.24 , pp. 207-228
    • Claxton, K.1    Ades, A.E.2    Lu, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.