Alterations in left ventricular function and cardiac biomarkers as a consequence of repetitive endurance cycling

European Journal of Sport Science

Volumn 9, Issue 2, 2009, Pages 97-105

  Williams, Karen ^a   Gregson, Warren ^a   Robertson, Colin ^a   Datson, Naomi ^a   Whyte, Greg ^a   Murrell, Carissa ^b   Wilson, Luke ^b   Ainslie, Philip ^b   Ross, Emma ^c   Shave, Rob ^c   Gaze, David ^c   George, Keith ^a  

^a LIVERPOOL JOHN MOORES UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OTAGO   (New Zealand)

^c BRUNEL UNIVERSITY   (United Kingdom)

Author keywords

Cardiac troponin I; Diastolic and systolic function; Tissue Doppler

Indexed keywords

EID: 67651046210     PISSN: 17461391     EISSN: 15367290     Source Type: Journal    
DOI: 10.1080/17461390902763391     Document Type: Article

References (28)

1. Bonetti, A., Tirelli, F., Albertini, R., Monica, C., Monica, M. and Tredici, G. (1996) Serum cardiac troponin T after repeated endurance exercise events. International Journal of Sports Medicine, 17, pp. 259-262.
2. George, K., Oxborough, D., Forster, J., Whyte, G., Shave, R. Dawson, E. et al. (2005) Mitral annular myocardial velocity assessment of segmental left ventricular diastolic function after prolonged exercise in humans. Journal of Physiology, 569, pp. 305-313.
3. George, K., Whyte, G., Stephenson, C., Shave, R., Dawson, E. Edwards, B. et al. (2004) Postexercise left ventricular function and cTnT in recreational marathon runners. Medicine and Science in Sports and Exercise, 36, pp. 1709-1715.
4. Giannaki, C. D., Oxborough, D. and George, K. (2008) Diastolic Doppler flow and tissue Doppler velocities during, and in recovery from, low-intensity, supine exercise. Applied Physiology. Nutrition and Metabolism, 33, pp. 896-902.
5. Halson, S. L., Bridge, M. W., Meeusen, R., Busschaert, B., Gleeson, M. Jones, D. A. et al. (2002) Time course of performance changes and fatigue markers during intensified training in trained cyclists. Journal of Applied Physiology, 93, pp. 947-956.
6. Hart, E., Dawson, E., Rasmussen, P., George, K., Secher, N. H. Whyte, G. et al. (2006) Beta-adrenergic receptor desensitization in man: Insight into post-exercise attenuation of cardiac function. Journal of Physiology, 577, pp. 717-725.
7. Hart, E., Shave, R., Middleton, N., George, K., Whyte, G. and Oxborough, D. (2007) Effect of preload augmentation on pulsed wave and tissue Doppler echocardiographic indices of diastolic function after a marathon. Journal of the American Society of Echocardiography, 20, pp. 1393-1399.
8. Laursen, P. B. and Rhodes, E. C. (2001) Factors affecting performance in an ultraendurance triathlon. Sports Medicine, 31, pp. 195-209.
9. Lucas, S. J., Anglem, N., Roberts, W. S., Anson, J. G., Palmer, C. D. Walker, R. J. et al. (2008) Intensity and physiological strain of competitive ultra-endurance exercise in humans. Journal of Sports Sciences, 26, pp. 477-489.
10. Middleton, N., George, K., Whyte, G., Gaze, D., Collinson, P. and Shave, R. (2008) Cardiac troponin T release is stimulated by endurance exercise in healthy humans. Journal of the American College of Cardiology, 52, pp. 1813-1814.
11. Middleton, N., Shave, R., George, K., Whyte, G., Hart, E. and Atkinson, G. (2006) Left ventricular function immediately following prolonged exercise: A meta-analysis. Medicine and Science in Sports and Exercise, 38, pp. 681-687.
12. Middleton, N., Shave, R., George, K., Whyte, G., Simpson, R. Florida-James, G. et al. (2007) Impact of repeated prolonged exercise bouts on cardiac function and biomarkers. Medicine and Science in Sports and Exercise, 39, pp. 83-90.
13. Nagueh, S. F., Mikati, I., Kopelen, H. A., Middleton, K. J., Quinones, M. A. and Zoghbi, W. A. (1998) Doppler estimation of left ventricular filling pressure in sinus tachycardia: A new application of tissue Doppler imaging. Circulation, 98, pp. 1644-1650.
14. Neilan, T. G., Januzzi, J. L., Lee-Lewandrowski, E., Ton-Nu, T. T., Yoerger, D. M. Jassal, D. S. et al. (2006) Myocardial injury and ventricular dysfunction related to training levels among nonelite participants in the Boston marathon. Circulation, 114, pp. 2325-2333.
15. Neumayr, G., Gaenzer, H., Pfister, R., Sturm, W., Schwarzacher, S. P. Eibl, G. et al. (2001) Plasma levels of cardiac troponin I after prolonged strenuous endurance exercise. American Journal of Cardiology, 87, pp. 369-371.
16. Neumayr, G., Pfister, R., Mitterbauer, G., Maurer, A., Gaenzer, H. Sturm, W. et al. (2002) Effect of the "Race Across The Alps" in elite cyclists on plasma cardiac troponins I and T. American Journal of Cardiology, 89, pp. 484-486.
17. Niessner, A., Zieglar, S., Slany, J., Billensteiner, E., Woloszczuk, W. and Geyer, G. (2003) Increases in plasma levels of atrial and brain natriuretic peptides after running a marathon: Are their effects partly counterbalanced by adrenocortical steroids?. European Journal of Endocrinology, 149, pp. 555-559.
18. Prasad, A., Popovic, Z. B., Arbab-Zadeh, A., Fu, Q., Palmer, D. Dijk, E. et al. (2007) The effects of aging and physical activity on Doppler measures of diastolic function. American Journal of Cardiology, 99, pp. 1629-1636.
19. Rifai, N., Douglas, P. S., O'Toole, M., Rimm, E. and Ginsberg, G. (1999) Cardiac troponin T and I, echocardiographic wall motion analyses, and ejection fractions in athletes participating in the Hawaii Ironman Triathlon. American Journal of Cardiology, 83, pp. 1085-1089.
20. Scott, J. M., Esch, B. T., Haykowsky, M. J., Isserow, S., Koehle, M. S. Hughes, B. G. et al. (2007) Sex differences in left ventricular function and beta-receptor responsiveness following prolonged strenuous exercise. Journal of Applied Physiology, 102, pp. 681-687.
21. Scott, J. M., Esch, B. T. A., Shave, R., Warburton, D. E. R., Gaze, D. and George, K. (2009) Cardiovascular consequences of completing a 100-mile ultra-marathon. Medicine and Science in Sports and Exercise, 41, pp. 26-34.
22. Seals, D. R., Rogers, M. A., Hagberg, J. M., Yamamoto, C., Cryer, P. E. and Eshani, E. E. (1988) Left ventricular dysfunction after prolonged strenuous exercise in healthy subjects. American Journal of Cardiology, 61, pp. 875-879.
23. Shave, R., Dawson, E., Whyte, G., George, K., Nimmo, M. Layden, J. et al. (2004) The impact of prolonged exercise in a cold environment upon cardiac function. Medicine and Science in Sports and Exercise, 36, pp. 1522-1527.
24. Shave, R., George, K. P., Atkinson, G., Hart, E., Middleton, N. Whyte, G. et al. (2007) Exercise-induced cardiac troponin T release: A meta-analysis. Medicine and Science in Sports and Exercise, 39, pp. 2099-2106.
25. Urhausen, A., Scharhag, J., Hermann, M. and Kindermann, W. (2004) Clinical significance of increased cardiac troponins T and I in participants of ultra-endurance events. American Journal of Cardiology, 94, pp. 696-698.
26. Welsh, R. C., Warburton, D. E., Humen, D. P., Taylor, D. A., McGavock, J. Haykowsky, M. J. et al. (2005) Prolonged strenuous exercise alters the cardiovascular response to dobutamine stimulation in male athletes. Journal of Physiology, 15, pp. 325-330.
27. Whyte, G., Lumley, S., George, K., Gates, P., Sharma, S. Prasad, K. et al. (2000) Cardiac fatigue following prolonged endurance exercise of differing distances. Medicine and Science in Sports and Exercise, 32, pp. 1067-1072.
28. Whyte, G., Stephens, N., Senior, R., George, K., Shave, R. Wilson, M. et al. (2007) Treat the patient, not the blood test: The implications of an increase in cardiac troponin after prolonged endurance exercise. British Journal of Sports Medicine, 41, pp. 613-615.