Adjuvant chemoradiation versus surgery alone for adenocarcinoma of the ampulla of Vater

Radiotherapy and Oncology

Volumn 92, Issue 2, 2009, Pages 244-248

  Zhou, Jessica ^a   Hsu, Charles C ^a   Winter, Jordan M ^a   Pawlik, Timothy M ^a   Laheru, Daniel ^a   Hughes, Michael A ^a   Donehower, Ross ^a   Wolfgang, Christopher ^a   Akbar, Umer ^a   Schulick, Richard ^a   Cameron, John ^a   Herman, Joseph M ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Adjuvant therapy; Ampulla of Vater; Ampullary cancer; Chemoradiation; Radiotherapy

Indexed keywords

ADENOCARCINOMA; ADJUVANT CHEMOTHERAPY; ADULT; AGED; ARTICLE; CANCER CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; COMPARATIVE STUDY; DISTANT METASTASIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MULTIMODALITY CANCER THERAPY; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGNOSIS; SURVIVAL TIME; TREATMENT OUTCOME; VATER PAPILLA; VATER PAPILLA ADENOCARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; AMPULLA OF VATER; COMBINED MODALITY THERAPY; COMMON BILE DUCT NEOPLASMS; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 67650948375     PISSN: 01678140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radonc.2009.05.006     Document Type: Article

References (19)

1. Yeo C.J., Cameron J.L., Sohn T.A., et al. Six hundred fifty consecutive pancreaticoduodenectomies in the 1990s. Pathology, complication and outcomes. Ann Surg 226 (1997) 248-260
2. Bouvet M., Gamagami R.A., Gilpin E.A., et al. Factors influencing survival after resection for periampullary neoplasms. Am J Surg 180 (2000) 13-17
3. Stephens J., Kuhn J., O'Brien J., et al. Surgical morbidity, mortality, and long term survival in patients with pancreatic cancer following pancreaticoduodenectomy. Am J Surg 174 (1997) 600-604
4. Kalser M.H., and Ellenberg S.S. Pancreatic cancer: adjuvant combined radiation and chemotherapy following curative resection. Arch Surg 120 (1985) 899-903
5. Matory Y.L., Gaynor J., and Brennan M. Carcinoma of the ampulla of Vator. Surg Gynecol Obstet 177 (1993) 366-370
6. Monson J.R.T., Donohue J.H., McEntee G.P., et al. Radical resection for carcinoma of the ampulla of Vater. Arch Surg 126 (1991) 353-357
7. Talamini M.A., Moesinger R.C., Pitt H.A., et al. Adenocarcinoma of the ampulla of Vater: a 28-year experience. Ann Surg 225 (1997) 590-600
8. De Castro S.M.M., Kuhlmann K.F.D., van Heek N.T., et al. Recurrent disease after microscopically radical (R0) resection of periampullary adenocarcinoma in patients without adjuvant therapy. J Gastrointest Surg 8 (2004) 775-784
9. Howe J.R., Klimstra D.S., Moccia R.D., Conlon K.C., and Brennan M.F. Factors predictive of survival in ampullary carcinoma. Ann Surg 228 (1998) 87-94
10. Brown K.M., Tompkins A.J., Yong S., Aranha G.V., and Shoup M. Pancreaticoduodenectomy is curative in the majority of patients with node-negative ampullary cancer. Arch Surg 140 (2005) 529-533
11. El-Ghazzawy A.G., Wade T.P., Virgo K.S., and Johnson F.E. Recent experience with the cancer of the ampulla of Vater in a national hospital group. Am Surg 61 (1995) 607-611
12. Gastrointestinal Tumor Study Group. Further evidence of effective adjuvant combined radiation and chemotherapy following curative resection of pancreatic cancer. Cancer 1987;59:2006-10.
13. Klinkenbijl J.H., Jeekel J., Sahmoud T., et al. Adjuvant radiotherapy and 5-Fluorouracil after curative resection of cancer of the pancreas and periampullary region. Phase III trial of the EORTC Gastrointestinal Tract Cancer Cooperative Group. Ann Surg 230 (1999) 776-784
14. Bhatia S., Miller R.C., Haddock M.G., Donohue J.H., and Krishnan S. Adjuvant therapy for ampullary carcinomas: the Mayo Clinic experience. Int J Radiat Oncol Biol Phys 66 (2006) 514-519
15. Kaplan E.L., and Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 53 (1958) 457-481
16. Cox D.R. Regression models and life-tables. J R Stat Soc B 34 (1972) 1187-1220
17. Willett C.G., Warshaw A.L., Convery K., and Compton C.C. Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. Surg Gynecol Obstet 176 (1993) 33-38
18. Lee J.H., Whittington R., Williams N.N., et al. Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomas. Int J Radiat Oncol Biol Phys 47 (2000) 945-953
19. Krishnan S., Rana V., Evans D.B., et al. Role of adjuvant chemoradiation therapy in adenocarcinomas of the ampulla of vater. Int J Radiat Oncol Biol Phys 70 (2008) 735-743