Long-term physical, hormonal, and sexual outcome of males with disorders of sex development

Journal of Pediatric Surgery

Volumn 44, Issue 8, 2009, Pages 1491-1496

  Kojima, Yoshiyuki ^a   Mizuno, Kentaro ^a   Nakane, Akihiro ^a   Kato, Toshiki ^a   Kohri, Kenjiro ^a   Hayashi, Yutaro ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

Disorders of sex development (DSD); Mixed gonadal dysgenesis; Ovotesticular DSD; Penis; Sexual function; Testis; XX testicular DSD

Indexed keywords

FOLLITROPIN; LUTEINIZING HORMONE; TESTOSTERONE;

ADOLESCENT; ADULT; ANDROGEN INSENSITIVITY SYNDROME; ARTICLE; BODY HEIGHT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; EJACULATION; FOLLITROPIN BLOOD LEVEL; FOLLOW UP; GONAD DEVELOPMENT; GONADAL DISEASE; GONADAL DYSGENESIS; HUMAN; HYPERGONADOTROPIC HYPOGONADISM; HYPOSPADIAS; INFANT; KARYOTYPE 45,X; KARYOTYPE 46,XX; KARYOTYPE 46,XY; LONG TERM CARE; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MASTURBATION; OVOTESTICULAR DISORDER OF SEX DEVELOPMENT; PENIS ERECTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEXUAL FUNCTION; SEXUAL INTERCOURSE; TESTICULAR DISORDER OF SEX DEVELOPMENT; TESTIS SIZE; TESTOSTERONE BLOOD LEVEL; UROLOGIC SURGERY;

FOLLICLE STIMULATING HORMONE; HUMANS; LUTEINIZING HORMONE; MALE; PENIS; SEX DIFFERENTIATION DISORDERS; SEXUAL BEHAVIOR; SEXUAL DEVELOPMENT; TESTIS; TESTOSTERONE; YOUNG ADULT;

EID: 67650941189     PISSN: 00223468     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2008.10.111     Document Type: Article

References (21)

1. Lee P.A., Houk C.P., Ahmed S.F., et al. International Consensus Conference on Intersex organized by the Lawson Wilkins Pediatric Endocrine Society and the European Society for Paediatric Endocrinology. Consensus statement on management of intersex disorders. International Consensus Conference on Intersex. Pediatrics 118 (2006) 488-500
2. Diamond M., and Beh H.G. Changes in the management of children with intersex conditions. Nat Clin Pract Endocrinol Metab 4 (2008) 4-5
3. Slijper F.M., Drop S.L., Molenaar J.C., et al. Long-term psychological evaluation of intersex children. Arch Sex Behav 27 (1998) 125-144
4. Nihoul-Fékété C., Thibaud E., Lortat-Jacob S., et al. Long-term surgical results and patient satisfaction with male pseudohermaphroditism or true hermaphroditism: a cohort of 63 patients. J Urol 175 (2006) 1878-1884
5. Verkauskas G., Jaubert F., Lortat-Jacob S., et al. The long-term follow-up of 33 cases of true hermaphroditism: a 40-year experience with conservative gonadal surgery. J Urol 177 (2007) 726-731
6. Wisniewski A.B., Migeon C.J., Meyer-Bahlburg H.F., et al. Complete androgen insensitivity syndrome: long-term medical, surgical, and psychosexual outcome. J Clin Endocrinol Metab 85 (2000) 2664-2669
7. Crouch N.S., Liao L.M., Woodhouse C.R., et al. Sexual function and genital sensitivity following feminizing genitoplasty for congenital adrenal hyperplasia. J Urol 179 (2008) 634-638
8. de la Chapelle A. The etiology of maleness in XX men. Hum Genet 58 (1981) 105-116
9. Knudtzon J., and Aarskog D. 45,X/46,XY mosaicism. A clinical review and report of ten cases. Eur J Pediatr 146 (1987) 2664-2669
10. Ogata T., and Matsuo N. Comparison of adult height between patients with XX and XY gonadal dysgenesis: support for a Y specific growth gene(s). J Med Genet 29 (1992) 539-541
11. Migeon C.J., Wisniewski A.B., Gearhart J.P., et al. Ambiguous genitalia with perineoscrotal hypospadias in 46,XY individuals: long-term medical, surgical, and psychosexual outcome. Pediatrics 110 (2002) e31
12. Mureau M.A., Slijper F.M., Nijman R.J., et al. Psychosexual adjustment of children and adolescents after different types of hypospadias surgery: a norm-related study. J Urol 154 (1995) 1902-1907
13. Bracka A. A long-term view of hypospadias. Br J Plast Surg 42 (1989) 251-255
14. Toublanc J.E., Boucekkine C., Abbas N., et al. Hormonal and molecular genetic findings in 46,XX subjects with sexual ambiguity and testicular differentiation. Eur J Pediatr 152 (1993) S70-S75
15. Arai T., Kitahara S., Horiuchi S., et al. Relationship of testicular volume to semen profiles and serum hormone concentrations in infertile Japanese males. Int J Fertil Womens Med 43 (1998) 40-47
16. Boucekkine C., Toublanc J.E., Abbas N., et al. Clinical and anatomical spectrum in XX sex reversed patients. Relationship to the presence of Y specific DNA-sequences. Clin Endocrinol 40 (1994) 733-742
17. Shannon R., and Nicolaides N.J. True hermaphroditism with oogenesis and spermatogenesis. Aust N Z J Obstet Gynaecol 13 (1973) 184-187
18. Starceski P.J., Sieber W.K., and Lee P.A. Fertility in true hermaphroditism. Adolesc Pediatr Gynecol 1 (1988) 55-56
19. Mieusset R., and Soulié M. Hypospadias: psychosocial, sexual, and reproductive consequences in adult life. J Androl 26 (2005) 163-168
20. Creighton S., and Minto C. Managing intersex. BMJ 323 (2001) 1264-1265
21. Rhoden E.L., and Morgentaler A. Testosterone replacement therapy in hypogonadal men at high risk for prostate cancer: results of 1 year of treatment in men with prostatic intraepithelial neoplasia. J Urol 170 (2003) 2348-2351