Vitamin B12 status, methylmalonic acidemia, and bacterial overgrowth in short bowel syndrome

Journal of Pediatric Gastroenterology and Nutrition

Volumn 48, Issue 4, 2009, Pages 495-497

  Sentongo, Timothy A ^a   Azzam, Ruba ^a   Charrow, Joel ^b  

^a UNIVERSITY OF CHICAGO   (United States)

^b CHILDREN'S MEMORIAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; METHYLMALONIC ACID; METRONIDAZOLE; PROPIONIC ACID;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL OVERGROWTH; CASE REPORT; CYANOCOBALAMIN DEFICIENCY; GASTROSTOMY; HUMAN; HYDROGEN BREATH TEST; LABORATORY TEST; MALE; METHYLMALONIC ACIDEMIA; PARENTERAL NUTRITION; PRIORITY JOURNAL; SHORT BOWEL SYNDROME; TREATMENT RESPONSE; VITAMIN BLOOD LEVEL;

ACIDOSIS; ADOLESCENT; HUMANS; INTESTINES; MALE; METHYLMALONIC ACID; SHORT BOWEL SYNDROME; VITAMIN B 12 DEFICIENCY;

BACTERIA (MICROORGANISMS);

EID: 67650917930     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31817f9e5b     Document Type: Article

References (21)

1. 12 deficiency. Early treatment may prevent devastating complications. Postgrad Med 2001;110:99-106.
2. 12 and folate deficiency: a guide for the primary care physician. Arch Intern Med 1999;159:1289-98.
3. Stabler SP, Allen RH, Savage DG, et al. Clinical spectrum and diagnosis of cobalamin deficiency. Blood 1990;76:871-81.
4. Young DS. Implementation of SI units for clinical laboratory data. Style specifications and conversion tables. Ann Intern Med 1987; 106:114-29.
5. Holleland G, Schneede J, Ueland PM, et al. Cobalamin deficiency in general practice. Assessment of the diagnostic utility and cost-benefit analysis of methylmalonic acid determination in relation to current diagnostic strategies. Clin Chem 1999;45:189-98.
6. Neale G, Gompertz D, Schonsby H, et al. The metabolic and nutritional consequences of bacterial overgrowth in the small intestine. Am J Clin Nutr 1972;25:1409-17.
7. 12 malabsorption in intestinal bacterial overgrowth. Gastroenterology 1972;62:255-60.
8. 12 deficiency. Ann Pharmacother 1999;33:641-3.
9. Brandt LJ, Bernstein LH, Wagle A. Production of vitamin B 12 analogues in patients with small-bowel bacterial overgrowth. Ann Intern Med 1977;87:546-51.
10. 12 analogues. Br J Haematol 1986;62:7-12.
11. Miller TL, Wolin MJ. Fermentations by saccharolytic intestinal bacteria. Am J Clin Nutr 1979;32:164-72.
12. Leonard JV. Stable isotope studies in propionic and methylmalonic acidaemia. Eur J Pediatr 1997;156 (Suppl 1):S67-9.
13. Bain MD, Jones M, Borriello SP, et al. Contribution of gut bacterial metabolism to human metabolic disease. Lancet 1988;1:1078-9.
14. Mellon AF, Deshpande SA, Mathers JC, et al. Effect of oral antibiotics on intestinal production of propionic acid. Arch Dis Child 2000;82:169-72.
15. Thompson GN, Chalmers RA, Walter JH, et al. The use of metronidazole in management of methylmalonic and propionic acidaemias. Eur J Pediatr 1990;149:792-6.
16. Lindenbaum J, Savage DG, Stabler SP, et al. Diagnosis of coba-lamin deficiency: II. Relative sensitivities of serum cobalamin, methylmalonic acid, and total homocysteine concentrations. Am J Hematol 1990;34:99-107.
17. Campbell NR. How safe are folic acid supplements? Arch Intern Med 1996;156:1638-44.
18. Food and Drug Administration. Food standards: amendment of standards of identity for enriched grain products to require addition of folic acid. Fed Reg 1996;61:8781-97.
19. Pfeiffer CM, Caudill SP, Gunter EW, et al. Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000. Am J Clin Nutr 2005;82:442-50.
20. Russell RM, Krasinski SD, Samloff IM, et al. Folic acid malab-sorption in atrophic gastritis. Possible compensation by bacterial folate synthesis. Gastroenterology 1986;91:1476-82.
21. Camilo E, Zimmerman J, Mason JB, et al. Folate synthesized by bacteria in the human upper small intestine is assimilated by the host. Gastroenterology 1996;110:991-8.