Laboratory assessment of the anticaries potential of a new dentifrice

Journal of Clinical Dentistry

Volumn 20, Issue 2, 2009, Pages 45-49

  Lippert, Frank ^a   Newby, Evelyn E ^a   Lynch, Richard J M ^a   Chauhan, Vijeash K ^a   Schemehorn, Bruce R ^b  

^a GLAXOSMITHKLINE   (United Kingdom)

^b Therametric Technologies Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ANTICARIES AGENT; ELMEX; FLUORIDE; FLUORIDE SODIUM; TIN FLUORIDE; TOOTHPASTE;

ARTICLE; DENTAL CARE; DRUG COMBINATION; ENAMEL; HUMAN; IN VITRO STUDY; METABOLISM; METHODOLOGY; PH; SALIVA; TOOTH DISEASE;

AMINES; CARIOSTATIC AGENTS; DENTAL ENAMEL; DENTIFRICES; DRUG COMBINATIONS; FLUORIDES; HUMANS; HYDROGEN-ION CONCENTRATION; SALIVA; SODIUM FLUORIDE; TIN FLUORIDES; TOOTH DEMINERALIZATION; TOOTH REMINERALIZATION;

EID: 67650905356     PISSN: 08958831     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Stephen KW: Dentifrices: Recent clinical findings and implications for use. Int Dent J 43 (Suppl):549-553, 1993.
2. White DJ: Reactivity of fluoride dentifrices with artificial caries. III. Quantitative aspects of acquired acid resistance (AAR): F uptake, retention, surface hardening and remineralization. J Clin Dent 3:6-14, 1991.
3. ten Cate JM: Fluorides in caries prevention and control: Empiricism or science. Caries Res 38:254-257,2004.
4. Jenkins GN: Theories on the mode of action of fluoride in reducing dental decay. J Dent Res 2:444-452,1963.
5. Stookey GK, DePaola PF, Featherstone JD, Fejerskov O, Möller IJ, Rotberg S, Stephen KW, Wefel JS: A critical review of the relative anticaries efficacy of sodium fluoride and sodium monofluorophosphate dentifrices. Caries Res 27:337-360,1993.
6. Leverett DH, McHugh WD, Jensen OE: Dental caries and staining after twenty-eight months of rinsing with stannous fluoride or sodium fluoride. J Dent Res 65:424-427, 1986.
7. White DJ: The application of in vitro models to research on demineralization and remineralization of the teeth. Adv Dent Res 9:175-193, 1995.
8. White DJ: Reactivity of fluoride dentifrices with artificial caries I. Effects on early lesions: F uptake, surface hardening and remineralization. Caries Res 21:126-140, 1987.
9. White DJ: Reactivity of fluoride dentifrices with artificial caries. II. Effects on subsurface lesions: F uptake, F distribution, surface hardening and remineralization. Caries Res 22:27-36, 1988.
10. Newby CS, Creeth JE, Rees GD, Schemehorn BR: Surface microhardness changes, enamel fluoride uptake, and fluoride availability from commercial toothpastes. J Clin Dent 17:94-99,2006.
11. Lynch RJ, Mony U, ten Cate JM: Effect of lesion characteristics and mineralizing solution type on enamel remineralization in vitro. Caries Res 41:257-262,2007.
12. Casals E, Boukpessi T, McQueen CM, Eversole SL, Faller RV: Anticaries potential of commercial dentifrices as determined by fluoridation and remineralization efficiency. J Contemp Dent Pract 8:1-10, 2007.
13. Toda S, Featherstone JD: Effects of fluoride dentifrices on enamel lesion formation. J Dent Res 87:224-247,2008.
14. Pfarrer AM, McQueen CM, Lawless MA, Rapozo-Hilo M, Featherstone JD: Anticaries potential of a stabilized stannous fluoride/sodium hexametaphosphate dentifrice. Compend Contin Educ Dent 26 (Suppl):41-46,2005.
15. McGaughey C, Stowell EC: Effects of polyphosphates on the solubility and mineralization of HA: Relevance to a rationale for anticaries activity. J Dent Res 56:579-587,1977.
16. McGaughey C: Binding of polyphosphates and phosphonates to hydroxya-patite, subsequent hydrolysis, phosphate exchange and effects on demineralization, mineralization and microcrystal aggregation. Caries Res 17:229-241, 1983.
17. Chan JC, Hill FJ, Newman HN: Uptake of fluoride by sound and artificially carious enamel in vitro following application of topical sodium and amine fluorides. J Dent 19:110-115, 1991.
18. Saxegaard E: Studies in the formation and dissolution of calcium fluoride in vitro and in vivo. Thesis, University of Oslo, 1988.
19. Petzold M: The influence of different fluoride compounds and treatment conditions on dental enamel: A descriptive in vitro study of the CaF(2) precipitation and microstructure. Caries Res 35 (Suppl):45-51,2001.
20. ten Cate JM: Current concepts on the theories of the mechanism of action of fluoride. Acta Odontol Scand 57:325-329, 1999.
21. Featherstone JD: Prevention and reversal of dental caries: Role of low level fluoride. Community Dent Oral Epidemiol 27:31-40, 1999.
22. Lynch RJM, Navada R, Walia R: Low-levels of fluoride in plaque and saliva and their effects on the demineralisation and remineralisation of enamel; Role of fluoride toothpastes. Int Dent J 54 (Suppl):304-309, 2004.
23. Clarkson BH, Fejerskov O, Silverstone LM, Ekstrand J: Rational use of fluoride in caries prevention. In: Fluoride in Dentistry, Ekstrand J, Fejerskov O, Silverstone LM, eds. Munksgaard International Publishers, Copenhagen, pp. 276-288, 1988.
24. Mellberg JR: Evaluation of topical fluoride preparations. J Dent Res 69 (Spec Iss):771-779, 1990.
25. Ingram GS, Higham SM, Edgar WM: Uptake of fluoride into enamel and caries reduction; Relationships and a pilot experiment in rats. In: Clinical and Biological Aspects of Dentifrices, Embery G, Rolla G, eds. Oxford University Press, Oxford, pp. 61-71, 1992.