Quantitative cell signalling analysis reveals down-regulation of MAPK pathway activation in colorectal cancer

Journal of Pathology

Volumn 218, Issue 4, 2009, Pages 514-519

  Gulmann, Christian ^a,c   Sheehan, Katherine M ^a,b,c   Conroy, Ronán M ^b   Wulfkuhle, Julia D ^c,d   Espina, Virginia ^c,d   Mullarkey, Michelle J ^b   Kay, Elaine W ^a,b   Liotta, Lance A ^c,d   Petricoin III, Emanuel F ^c,d  

^a BEAUMONT HOSPITAL   (Ireland)

^b ROYAL COLLEGE OF SURGEONS IN IRELAND   (Ireland)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d GEORGE MASON UNIVERSITY   (United States)

Author keywords

Colorectal cancer; Erk; MAPK; p38; Phosphorylation; Proteomics

Indexed keywords

ANTIBODY; MISMATCH REPAIR PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CLINICAL ARTICLE; COLON RESECTION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; MALE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PHOSPHORYLATION; PROTEOMICS; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; COLORECTAL NEOPLASMS; DNA MISMATCH REPAIR; DOWN-REGULATION; ENZYME ACTIVATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MALE; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM STAGING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION;

EID: 67650901206     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2561     Document Type: Article

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