Mutagenesis of varicella-zoster virus glycoprotein B: Putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo

Journal of Virology

Volumn 83, Issue 15, 2009, Pages 7495-7506

  Oliver, Stefan L ^a   Sommer, Marvin ^a   Zerboni, Leigh ^a   Rajamani, Jaya ^a   Grose, Charles ^b   Arvin, Ann M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FURIN; HYBRID PROTEIN; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS GLYCOPROTEIN B;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DELETION MUTANT; GENE EXPRESSION; HERPES ZOSTER; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN MOTIF; VARICELLA ZOSTER VIRUS; VIRION; VIRUS GENOME; VIRUS MORPHOLOGY; VIRUS MUTATION; VIRUS PATHOGENESIS; VIRUS PLAQUE; VIRUS REPLICATION; XENOGRAFT;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CHICKENPOX; FURIN; HERPESVIRUS 3, HUMAN; HUMANS; MICE; MICE, SCID; MOLECULAR SEQUENCE DATA; MUTAGENESIS; MUTATION; PROTEIN BINDING; SEQUENCE ALIGNMENT; SKIN; VIRAL ENVELOPE PROTEINS; VIRUS REPLICATION;

BACTERIA (MICROORGANISMS); HERPESVIRIDAE; HUMAN HERPESVIRUS 3; SIMPLEXVIRUS;

EID: 67650891906     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00400-09     Document Type: Article

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