Developmental exposure to PCBs, MeHg, or both: Long-term effects on auditory function

Environmental Health Perspectives

Volumn 117, Issue 7, 2009, Pages 1101-1107

  Powers, Brian E ^a   Poon, Emily ^a   Sable, Helen J K ^b   Schantz, Susan L ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b University of Memphis   (United States)

Author keywords

ABR; Auditory; Development; DPOAE; MeHg; PCB

Indexed keywords

CORN OIL; METHYLMERCURY; POLYCHLORINATED BIPHENYL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUDITORY THRESHOLD; BREEDING; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; DRUG EXPOSURE; ENVIRONMENTAL EXPOSURE; FEMALE; HEARING IMPAIRMENT; MALE; NONHUMAN; PERINATAL PERIOD; PHYSICAL DEVELOPMENT; PREGNANCY; PRIORITY JOURNAL; RAT; WEANING;

ANIMALS; EVOKED POTENTIALS, AUDITORY, BRAIN STEM; FEMALE; MATERNAL EXPOSURE; METHYLMERCURY COMPOUNDS; POLYCHLORINATED BIPHENYLS; PREGNANCY; RATS; RATS, LONG-EVANS;

RATTUS; ZEA MAYS;

EID: 67650863450     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0800428     Document Type: Article

References (40)

1. Bemis JC, Seegal RF. 1999. Polychlorinated biphenyls and methylmercury act synergistically to reduce rat brain dopamine content in vitro. Environ Health Perspect 107:879-885.
2. Bemis JC, Seegal RF. 2000. Polychlorinated biphenyls and methylmercury after intracellular calcium concentrations in rat cerebellar granule cells. Neurotoxicology 21(6):1123-1134.
3. Cerna M, Maly M, Grabic R, Batariova A, Smid J, Benes B. 2008. Serum concentrations of indicator PCB congeners in the Czech adult population. Chemosphere 72(8):1124-1131.
4. Chen YJ, Hsu CC. 1994. Effects of prenatal exposure to PCBs on the neurological function of children: a neuropsychological and neurophysiological study. Dev Med Child Neurol 36(4):312-320.
5. Chuu JJ, Hsu CJ, Lin-Shiau SY. 2001. Abnormal auditory brainstem responses for mice treated with mercurial compounds: involvement of excessive nitric oxide. Toxicology 162(1):11-22.
6. Crofton KM, Ding DL, Padich R, Taylor M, Henderson D. 2000. Hearing loss following exposure during development to polychlorinated biphenyls: a cochlear site of action. Hear Res 144:196-204.
7. Crofton KM, Rice DC. 1999. Low-frequency hearing loss following perinatal exposure to 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) in rats. Neurotoxicol Teratol 21(3):299-301.
8. Fischer C, Fredriksson A, Eriksson P. 2008. Neonatal co-exposure to low doses of an ortho-PCB (PCB153) and methyl mercury exacerbate defective developmental neurobehavior in mice. Toxicology 244(2-3):157-165.
9. Goldey ES, Crofton KM. 1998. Thyroxine replacement attenuates hypothyroxinemia, hearing loss, and motor deficits following developmental exposure to Aroclor 1254 in rats. Toxicol Sci 45:94-105.
10. Goldey ES, Kahn LS, Lau C, Rehnberg GL, Crofton KM. 1995. Developmental exposure to polychlorinated biphenyls (Aroclor 1254) reduces circulating thyroid hormone concentrations and causes hearing deficits in rats. Toxicol Appl Pharmacol 135:77-88.
11. Grandjean P, Weihe P, Bursa VW, Needham LL, Storr-Hansen E, Heinzow B, et al. 2001. Neurobehavioral deficits associated with PCB in 7-year-old children prenatally exposed to seafood neurotoxicants. Nourotoxicol Teratol 23(4):305-317.
12. Herr DW, Goldey ES, Crofton KM. 1996. Developmental exposure to Aroclor 1254 produces low-frequency alterations in adult rat brainstem auditory evoked responses. Fundam Appl Toxicol 33:120-128.
13. Huang CF, Hsu CJ, Liu SH, Lin-Shiau SY. 2008. Neurotoxicological mechanism of methylmercury induced by lowdose and long-term exposure in mice: oxidative stress and down-regulated Na+/K(+)-ATPase involved. Toxicol Left 176(3):188-197.
14. Kenet T, Froemke RC, Schreiner CE, Pessah IN, Merzenich MM. 2007. Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex. Proc Natl Acad Sci USA 104(18):7646-7651.
15. Knipper M, Zinn C, Maier H, Praetorius M, Rohbock K, Kopschall I, et al. 2000. Thyroid hormone deficiency before the onset of hearing causes irreversible damage to peripheral and central auditory systems. J Neurophysiol 83(5):3101-3112.
16. Kostyniak PJ, Hansen LG, Widbolm JJ, Fitzpatrick RD, Olson JR, Helferich JL, et al. 2005. Formulation and characterization of an experimental PCB mixture designed to mimic human exposure from contaminated fish. Toxicol Sci 88(2):400-411.
17. Lasky RE, Widholm JJ, Crofton KM, Schantz SL. 2002. Perinatal exposure to Aroclor 1254 impairs distortion product otoacoustic emissions (DPOAEs) in rats. Toxicol Sci 68:458-464.
18. Longnecker MP, Hoffman HJ, Klebanoff MA, Brock JW, Zhou H, Needham L, et al. 2004. In utero exposure to polychlorinated biphenyls and sensorineural hearing loss in 8-yearold children. Neurotoxicol Teratol 26(5):629-637.
19. Lonsbury-Martin BL, Martin GK. 1990. The clinical utility of distortion- product otoacoustic emissions. Ear Hear 11(2):144-154.
20. Murata K, Weihe P, Araki S, Budtz-Jorgensen E, Grandjean P. 1999. Evoked potentials in Faroese children prenatally exposed to methylmercury. Neurotoxicol Teratol 21:471-472.
21. Murata K, Weihe P, Budtz-Jorgensen E, Jorgensen PJ, Grandjean P. 2004. Delayed brainstem auditory evoked potential latencies in 14-year-old children exposed to methylmercury. J Pediatr 144:177-183.
22. National Institutes of Health. 2002. Public Health Service Policy on Humane Care and Use of Laboratory Animals. Rockville, MD:NIH/Office of Laboratory Animal Welfare.
23. National Research Council, Institute for Laboratory Animal Research. 2003. Guidelines for the Card and Use of Mammals in Neuroscience and Behavioral Research. Washington, DC:National Academy Press.
24. Powers BE, Widholm JJ, Lasky RE, Schantz SL. 2006. Auditory deficits in rats exposed to an environmental PCB mixture during development. Toxicol Sci. 89(2):415-422.
25. Rice DC. 1998. Age-related increase in auditory impairment in monkeys exposed in utero plus postnatally to methylmercury. Toxicol Sci. 44(2):191-196.
26. Rice DC, Gilbert SG. 1992. Exposure to methyl mercury from birth to adulthood impairs high-frequoncy hearing in monkeys. Toxicol Appl Pharmacol 115(19):6-10.
27. Roegge CS, Wang VC, Powers BE, Klintsova AY, Villeraal S, Greennugh WT, et al. 2004. Motor impairment in rats exposed to PCBs and methylmercury during development. Toxicol Sci 77(2):315-324.
28. Rogan WJ, Gladen BC, McKinney JD, Carreras N, Hardy P, Thullen J, et al. 1986a. Neonatal effects of transplacental exposure to PCBs and DDE. J Pediatr 169(2):335-341.
29. Rogan WJ, Gladen BC, McKinney JD, Carreras N, Hardy P, Thullen J, et al. 1986b. Polychlorinated biphenyls (PCBs) and dichlorodiphenyl dichloroethene (DDE) in human milk: effects of maternal factors and previous lactation, AM J Public Health 76(2):172-177.
30. Sable HJK, Eubig PA, Powers BE, Wang VC, Schantz SL 2009. Developmental exposure to PCBs and/or MeHg: effects on a differential reinforcement of low rates (DRL) operant task before and after amphetamine drug challenge. Neurotoxicol Teratol; doi: 10.1016/j.ntt.2008.12.006 [Online 21 January 2009].
31. Sher ES, Xu XM, Adams PM, Craft CM, Stein SA. 1998. The effects of thyroid hormone level and action in developing brain: are these targets for the actions of polychlorinated biphenyls and dioxins? Toxicol Ind Health 14(1-2):121-158.
32. Stewart PW, Reihman J, Lonky El, Dervill TJ, Pagano J. 2003. Cognitive development in preschool children prenatally exposed to PCBs and MeHg. Neurotoxicol Teratol 25(1):11-22.
33. Ulbrich B, Stahlmann R. 2004. Developmental toxicity of polychlorinated biphenyls (PCBs): a systematic review of experimental data. Arch Toxicol 78:252-268.
34. Uziel A, Gabrion J, Ohresser M, Legrand C. 1981. Effects of hypothyroidism on the structural development of the organ of Corti in the rat. Acta Otolaryngol 92(5-6):469-480.
35. Uziel A, Rabie A, Marot M. 1980. The effect of hypothyroidism on the onset of cochlear potentials in developing rats. Brain Res 182(1):172-175.
36. Vrougdenhil HJ, Van Zanten GA, Brocaar MP, Mulder PG, Weisglas-Kuperus N. 2004. Prenatal exposure to polychlorinated biphenyls and breastfeeding: opposing effects on auditory P300 latencies in 9-year-old Dutch children. Dev Med Child Neurol 46(6):398-405.
37. Watanabe C, Satoh H. 1996. Evolution of our understanding of methylmercury as a health threat. Environ Health Perspect 104(suppl 2):367-379.
38. Widholm JJ, Villereal S, Seegal RF, Schantz SL. 2004. Spatial alternation deficits following developmental exposure to Aroclor 1254 and/or methylmercury in rats. Toxicol Sci 82(2):577-589.
39. Wigle DT, Arbuckle TE, Turner MC, Berube A, Yang O, Shiliang L, et al. 2008. Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants. J Toxicol Environ Health B Crit Rev 5-6:373-517.
40. Wong PW, Pessah IN. 1997. Noncoplanar PCB 95 alters microsomal calcium transport by an immunophilin FKBP12dependent mechanism. Mol Pharmacol 51(5):693-702.