Plant species used in the treatment of diabetes by South African traditional healers: An inventory

Pharmaceutical Biology

Volumn 47, Issue 4, 2009, Pages 348-365

  Deutschlnder, M S ^a   Lall, N ^a   Van De Venter, M ^b  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b NELSON MANDELA METROPOLITAN UNIVERSITY   (South Africa)

Author keywords

Diabetes; Herbalists; Plants; South Africa; Traditional healers

Indexed keywords

HERBACEOUS AGENT;

ALOE; ALOE FEROX; ANACARDIACEAE; ARTEMISIA; ARTEMISIA AFRA; ASCLEPIADACEAE; ASTERACEAE; BARK; BRACHYLAENA DISCOLOR; BRACHYLAENA ELLIPTICA; BRACHYLAENA ILICIFOLIA; BRIDELIA MICRANTHA; BULBINE LATIFOLIA; CARPOBROTUS EDULIS; CATHARANTHUS ROSEUS; CELASTRACEAE; CHIRONIA BACCIFERA; CISSAMPELOS; CISSAMPELOS CAPENSIS; CNICUS; CNICUS BENEDICTUS; DIABETES MELLITUS; DRUG ACTIVITY; EBENACEAE; ELAEODENDRON TRANSVAALENSE; ETHNOBOTANY; EUCLEA NATALENSIS; EUCLEA UNDULATA; EUPHORBIA; FENUGREEK; FRUIT; GENTIANACEAE; HARPAGOPHYTUM; HARPAGOPHYTUM PROCUMBENS; HOODIA CURRORII; HUMAN; JUJUBE; KEDROSTIS NANA; LANNEA EDULIS; LEGUME; MEDICINAL PLANT; MESEMBRYANTHEMUM; MOMORDICA; MOMORDICA BALSAMINA; NYMPHAEA; NYMPHAEA NOUCHALI; PHYTOCHEMISTRY; PLANT LEAF; PLANT ROOT; PLANT TUBER; PTERONIA DIVARICATA; REVIEW; RHIZOME; SCHKUHRIA PINNATA; SCLEROCARYA BIRREA; SPIROSTACHYS AFRICANUS; SUTHERLANDIA FRUTESCENS; TERMINALIA; TERMINALIA SERICEA; TRADITIONAL MEDICINE; VERNONIA; VERNONIA OLIGOCEPHALA; WARBURGIA SALUTARIS; ZIZIPHUS MUCRONATA;

EID: 67650854692     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880200902752959     Document Type: Review

References (88)

1. Basch E, Dacey C, Hammerness P, Hashmi S, Ulbricht C, Vora M, Weissner W (2006): Blessed thistle (Cnicus benedictus L.). Monograph Natural Standard Research Collaboration, US National Library of Medicine, National Institute of Health/Department of Health & Human Services, Bethesda. Available at: http://www.nlm.nih.gov/medlineplus/druginfo/natural/patient- blessedthistle.html (accessed 3 March 2008).
2. Bell EA, Lackey JA, Polhill RM (1978): Systematic significance of canavanine in the Papilionoideae (Faboideae). Biochem Syst Ecol 6: 201-212.
3. Bohlman F, Scheidges C, Misra LN, Jakupovic J (1984): Further glaucolides from South African Vernonia species. Phytochemistry 23: 1795-1798.
4. Bombardelli E, Bonati A, Gabetta B, Mustich G (1974): Triterpenoids of Terminalia sericea. Phytochemistry 13: 2559-2562.
5. Botha DJ (1980): The identity of Antizoma harveyana Miers ex Harv. and A capensis (L.f.) Diels. J SAfr Bot 46: 1-5.
6. Bromilow C (1995): Problem Plants of South Africa. Arcadia, Briza Publications, pp. 1-315.
7. Bruce WGG (1975): Medicinal properties of Aloe. Excelsa 5: 57-68.
8. Bruneton J (1995): Pharmacognosy, Phytochemistry, Medicinal Plants, 2nd edn. London, Intercept, pp. 1-915.
9. Buckingham J (1996): Dictionary of Natural Products, CD-ROM 4:2. London, Chapman & Hall.
10. Charlson AJ (1980): Antoneoplastic constituents of some southern African plants. J Ethnopharmacol 2: 323-335.
11. Chrubasik S, Zimpfer CH, Schutt U, Ziegler R (1996): Effectiveness of Harpagophytum procumbens in the treatment of acute low back pain. Phytomedicine 3: 1-10.
12. Coates Palgrave K (1984): Trees of Southern Africa. Cape Town, Struik, pp. 1-959.
13. Coates Palgrave K (2002): Trees of Southern Africa, 3rd edn. Cape Town, Struik, pp. 1-1212.
14. Costa MAC, Paul MI, Alves AAC, Van der Vyver LM (1978): Aliphatic andtriterpenoid compounds of Ebenaceae species. Rev Port Farm 28: 171-174.
15. Cunningham AB (1997): An African-wide overview of medicinal plant harvesting, conservation and health care. Non-Wood Forest Products 11: 116-129.
16. Czygan FC, Krüger A (1977): Pharmazeutisch-biologische Untersuchungen der Gattung Harpagophytum. Planta Med 31: 305-307.
17. Dold AP, Cocks ML (2002): The trade in medicinal plants in the Eastern Cape Province, South Africa. SAfr J Sci 98: 589-597.
18. Drewes SE, Mashimbye MJ (1993): Flavanoids and triterpenoids from Cassinepapillosa and the absolute configuration of 11,11-dimethyl-1,3,8, 10 - tetrahydroxyl-9-mathoxypeltogynan. Phytochemistry 32: 1041-1044.
19. Dyer RA, Codd LE, Rycroft HB (1963): Flora of Southern Africa, Vol. 26. Pretoria, Government Printers, pp. 1-307.
20. Ferreira MA, Alves AC, Costa MAC, Paul MI (1977): Naphthoquinone dimers and trimers from Euclea natalensis. Phytochemistry 16: 117-120.
21. Frost C (1941): An investigation of the active constituents and pharmacological effects of the bark of the Pseudocassine transvaalensis. S Afr Med Sci 6: 57-58.
22. Galvez J, Crespo ME, Zarzuelo A, De Witte P, Spiessens C (1993): Pharmacological activity of a procyanidin isolated from Sclerocarya birrea bark: Antidiarrhoeal activity and effects on isolated guinea-pig ileum. Phytother Res 7: 25-28.
23. Grabandt K (1985): Weeds of Crops and Gardens in Southern Africa. Johannesburg, Seal Publishing, pp. 1-135.
24. Graven E, Deans S, Mavi S, Gundidza M.G., Svoboda KP (1992): Antimicrobial and anti oxidative properties of the volatile (essential) oil of Artemisia afra Jacq. Flavour Fragrance J 7: 121-123.
25. Henderson L (2001): Alien Weeds and Invasive Plants: A Complete Guide to Declared Weeds and Invaders in South Africa. Cape Town, Agricultural Research Council, Paarl Printers, pp. 1-300.
26. Henderson M, Anderson JG (1966): Common Weeds in South Africa. Memoirs of the Botanical Survey of South Africa, Vol. 37. Pretoria, Botanical Research Institute, pp. 1-440.
27. Hilliard OM (1977): Compositae in Natal. Pietermaritzburg, University of Natal Press, pp. 360-361.
28. Holmstedt BR, Bruhn JG (1995): Ethnopharmacology - A challenge. In: Schultes RE, Von Reis S, eds., Ethnobotany, Evolution of a Discipline. Portland, OR, Dioscorides Press, pp. 338-343.
29. Hutchings A (1989): Observations on plant usage in Xhosa and Zulu medicine. Bothalia 19: 225-235.
30. Hutchings A, Scott AH, Lewis G, Cunningham A (1996): Zulu Medicinal Plants: An Inventory. Pietermaritzburg, University of Natal Press, pp. 1-450.
31. Iwu MM (1993): Handbook of African Medicinal Plants. Boca Raton, FL, CRC Press, pp.1-435.
32. Jakupovic J, Klenmeyer H, Bohlmann F, Graven E (1988): Glaucolides and guaianolides from Artemisia afra. Phytochemistry 27: 1129-1134.
33. Khan MR (1985): Isolation of 4,8-dihydroxy-6-methyl-1-tetralone from the root bark of Euclea natalensis. PlantaMed 5:356.
34. Lall N, Meyer JMM (1999): In vitro inhibition of drug-resistant and drug-sensitive strains of Mycobacterium tuberculosis by ethnobotanically selected South African plants. J Ethnopharmacol 66: 347-354.
35. Lall N, Meyer JMM (2001): Antibacterial activity of water and acetone extracts of the roots of Euclea natalensis. J Ethnopharmacol 72: 313-316.
36. Le Roux A (2005): Namaqualand South African Wild Flower Guide 1. Botanical Society of South Africa, Cape Town. pp. 1-336.
37. Lonergan G, Routsi E, Georgiadis T, Agelis G, Hondrelis J, Matsoukas J, Larsen LK, Caplan FR (1992): Isolation, NMR studies and biological activities of onopordopicrin from Centaurea sonchifolia. J Nat Prod 55: 225-228.
38. Mabogo DEN (1990): The Ethnobotany of the Vhavenda. M.Sc. Thesis, University of Pretoria, pp. 1-260.
39. Mander M (1998): Marketing of Medicinal Plants in South Africa. A Case Study in KwaZulu-Natal. Rome, Food and Agricultural Organization of the United Nations, pp. 1-151.
40. Manning J, Goldblatt P (2000): West Coast. South African Wild Flower Guide 7. Cape Town, Botanical Society of South Africa, pp. 1-240.
41. Mbanya J, Gwangwa ST (1997): Dietary management of diabetes mellitus in Africa. In: Alberti KGMM, Zimmet P, DeFronzo RA, Keen H., eds., International Textbook of Diabetes Mellitus, 2nd edn. New York, John Wiley, pp. 785-790.
42. Momordicabalsamina L. (2006): BioNatural Momordica balsamina L. pp. 1-3. Available at: http://www.geocities.com/bionaturalza/momordica.html (accessed 3 March 2008).
43. Mulholland DA, Drewes SE (2004): Global phytochemistry: Indigenous medicinal chemistry on track in southern Africa. Phytochemistry 65: 769-782.
44. Mushtaq A, Khan MA, Arshad M, Zafar M. (2007). Ethnophytotherapical approaches for the treatment of diabetes by the local inhabitants of district Attock (Pakistan). Available at: http://www.siu.edu/~ebl/leaflets/phyto.htm (accessed 3 July 2008).
45. Perry EK, Ashton H & Young AH (2002) Neoro chemistry of consciousness: Neorotransmitters in mind. John Benjamins Publishing Company. pp. 1-344.
46. Phillipson JD (1999): New drugs from nature - It could be yew. Phytother Res 13: 2-8.
47. Phillipson JD (2001): Phytochemistry and medicinal plants. Phytochemistry 56: 237-243.
48. Phytochemicals (2007a): Ellagic acid. Available at: http://www. phytochemicals.info/phytochemicals/ellagic-acid.php (accessed 21 August 2007).
49. Phytochemicals (2007b): Gallic acid. Available at: http://www. phytochemicals.info/phytochemicals/gallic-acid.php (accessed 21 August 2007).
50. Pooley E (1998): A Field Guide to Wild Flowers KwaZulu-Natal and the Eastern Region. Durban, Natal Flora Publications Trust, Natal Herbarium, pp. 1-630.
51. Pourrat H, Texier O, Venatt B (1986): Study of the stability of Harpagophytum procumbens DC. iridoids during the preparation of drug powders and atomized extracts. Ann Pharm Fr 43: 601-606.
52. Pujol J (1990): Natur Africa - The Herbalist Handbook: African Flora, Medicinal Plants. Durban, Jean Pujol Natural Healers Foundation, pp. 1-192.
53. Rabe T, Van Staden J (1997): Antibacterial activity of South African plants used for medicinal purposes. J Ethnopharmacol 56: 81-87.
54. Rabe T, Van Staden J (2000): Isolation of an antibacterial sesquiterpenoid from Warburgia salutaris. J Ethnopharmacol 73: 171-174.
55. Rogers CB (1996): Chemistry and biological properties of the African Combretaceae. Paper presented at the IOCD Symposium, Victoria Falls, Zimbabwe, 25 to 28 February.
56. Rood B (1994): Uit die Veldapteek. Cape Town, Tafelberg-Uitgewers Bpk, pp. 1-115.
57. Silbernagel E, Spreitzer H, Buchbauer G (1990): Non-volatile constituents of Artemisia afra. Monatsch Chem 121: 433-436.
58. Smith CA (1966): Common Names of South African Plants. Memoirs of the Botanical Survey of South Africa, Vol. 35. Pretoria, Government Printer, pp. 1-642.
59. South African National Biodiversity Institute, South African Medical Research Council, University of the Western Cape (2005): Euclea undulata Herba. Available at: http://www.plantzafrica.com/med-monographs/eucleaundulata. pdf (accessed 28 November 2005).
60. South African National Biodiversity Institute, South African Medical Research Council, University of the Western Cape (2006a): Artemisia afra Herba. Available at: http://www.plantzafrica.com/medmonographs/ artemisiaafra.pdf (accessed 4 April 2006).
61. South African National Biodiversity Institute, South African Medical Research Council, University of the Western Cape (2006b): Sutherlandia frutescens Herba. Available at: http://www.plant-zafrica.com/medmonographs/ sutherlandiafrutescens.pdf (accessed 4 March 2006).
62. South African Traditional Medicines Research Unit (2005) Traditional Medicines. Department of Pharmacology, Faculty of Health Sciences, University of Cape Town, South Africa. Available at: http://www.sahealthinfo.org/ traditionalmeds/traditionalmeds.htm (accessed 25 November 2005).
63. Southon IW (1994): Phytochemical Dictionary of the Leguminosae. London, Chapman & Hall, pp. 1-1180.
64. Suttie JM (2007): Trigonella foenum-graecum L. pp. 1-3 Available at: http://www.fao.org/AG/AGP/agpc/doc/Gbase/DATA/pf000412.htm (accessed 30 July 2007).
65. Suzuki I (1981) Anti-inflammatory agent. Eur Pat Appl 25, 873 (CIA61K35/78), 1 April 1981.
66. Tannock J (1973): Naphthoquinones from Diospyros and Euclea species. Phytochemistry 12: 2066-2067.
67. Taylor L (2006). Tropical plant database: Database for Chanchalagua (Schkuhria pinnata), Raintree nutrition. Available at: http://www.rain-tree.com/canchalagua.htm (accessed 3 March 2008).
68. Van der Vyver LM, Gerritsma KW (1973): Naphtoquinones of Euclea and Diospyros species. Phytochemistry 12: 230-231.
69. Van der Vyver LM, Gerritsma KW (1974): Napthoquinones of Euclea and Diospyros species. Phytochemistry 13: 2322-2323.
70. Van Huyssteen M (2003): Evaluation of African Traditional Healing in the Management of Diabetes Mellitus in the Nelson Mandela Metropole. MSc Thesis, Nelson Mandela Metropolitan University, Port Elizabeth, pp. 1-128.
71. Van Rooyen N (2001): Flowering plants of the Kalahari dunes. Lynnwood, Pretoria, Ecotrust BK, pp. 1-216.
72. Van Staden LF, Drewes SE (1994) Knipholone from Bulbine latifolia and Bulbine frutescens. Phytochemistry 35: 685-686.
73. Van Wyk AE, Malan SJ (1988): Veldgids tot die veldblomme van die Witwatersrand- & Pretoriagebied. Kaapstad, Struik, pp. 1-352.
74. Van Wyk B-E, Gericke N (2000): People's Plants. Pretoria, Briza Publications, pp. 1-351.
75. Van Wyk B-E, Smith G (1996): Guide to the Aloes of South Africa. Pretoria, Briza Publications, pp. 1-302.
76. Van Wyk B-E, Van Heerden F, Van Oudtshoorn B (2002): Poisonous Plants of South Africa. Pretoria, Briza Publications, pp. 1-288.
77. Van Wyk B-E, Van Oudtshoorn B, Gericke N (2005): Medicinal Plants of South Africa. Pretoria, Briza Publications, pp. 1-304.
78. Van Wyk B-E, Wink M (2004): Medicinal Plants of the World. Pretoria, Briza Publications, pp. 1-480.
79. Van Wyk B-E, Yenesew A, Dagne E (1995): Chemotaxonomic significance ofanthraquinones in the roots of Asphodeloideae (Asphodelaceae). Biochem Sys Ecol 23: 277-281.
80. Van Wyk B, Van Wyk P (1997): Field Guide to Trees of Southern Africa. Cape Town, Struik Publishers, pp. 1-536.
81. Van Wyk B, Van Wyk P, Van Wyk B-E (2000): Photographic Guide to Trees of Southern Africa. Pretoria, Briza Publications, pp. 1-356.
82. Venter F, Venter J-A (1996): Making the Most of Indigenous Trees. Pretoria, Briza Publications, pp. 1-304.
83. Viljoen C, Notten A (2002) Nymphaea nouchali Burm. F. var. caerulea (Sav.) Verdc. Cape Town, Kirstenboch National Botanical Gardens, pp. 1-6. Available at: http://www.plant-zafrica.com/plantnop/nympnouch.htm (accessed 12 June 2007).
84. Von Koenen E (2001): Medicinal, Poisonous, and Edible Plants of Namibia. Windhoek, Klaus Hess Publishers, pp. 1-335.
85. Watt JM, Breyer-Brandwijk MG (1962): The Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd edn. London, Livingston, pp. 1-1457.
86. World Health Organization (1994): Prevention of Diabetes Mellitus: Report of a WHO study group on diabetes mellitus. WHO Technical report series No. 844. Geneva, World Health Organization, pp.1-108.
87. Wolfender J-L, Hamburger M, Hostettman K, Msonthi JD, Mavi S (1993): Search for bitter principles in Chironia species by LC-MS and isolation of a new secoiridoid diglycoside from Chironia krebsii. J Nat Prod 56: 682-689.
88. Wollenweber E, Mann K, Valant-Vetschera KM (1989): External flavonoid aglycones in Artemisia and some further Anthemidae (Asteraceae). Fitoterapia 60: 460-463.