Cytotoxic bisnor- and norditerpene dilactones having 7α,8α- epoxy-9,11-enolide substructure from Podocarpus macrophyllus D. Don

Chemical and Pharmaceutical Bulletin

Volumn 57, Issue 7, 2009, Pages 668-679

  Sato, Kimihiko ^a   Inaba, Yasunori ^a   Park, Hyun Sun ^b   Akiyama, Toshiyuki ^b   Koyama, Tetsuo ^b   Fukaya, Haruhiko ^a   Aoyagi, Yutaka ^a   Takeya, Koichi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

^b Kochi Prefectural Makino Botanical Garden ^*  (Japan)

Author keywords

7 ,8 epoxy 8,11 enolide substructure; Cytotoxic activity; Norditerpene dilactone; Podocarpus macrophyllus

Indexed keywords

MAKILACTONE; NAGILACTONE; NORDITERPENOIDE; PLANT EXTRACT; PODOLACTONE B; RAKANMAKILACTONE D; SELLOWIN B; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; CYTOTOXICITY; LEUKEMIA P 388; MURINE LEUKEMIA; NONHUMAN; PODOCARPUS MACROPHYLLUS; SPECTROSCOPY; TREE; X RAY CRYSTALLOGRAPHY;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CONIFEROPHYTA; DOSE-RESPONSE RELATIONSHIP, DRUG; MICE; MODELS, MOLECULAR; MOLECULAR BIOLOGY; TERPENES;

EID: 67650841822     PISSN: 00092363     EISSN: 13475223     Source Type: Journal    
DOI: 10.1248/cpb.57.668     Document Type: Article

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14. Crystallographic data for compound 1 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712026. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
15. Crystallographic data for compound 2 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712027. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
16. Crystallographic data for compound 3 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712028. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
17. Crystallographic data for compound 4 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712029. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
18. Crystallographic data for compound 5 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712030. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
19. Crystallographic data for compound 6 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712031. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
20. Crystallographic data for compound 7 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712032. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
21. Crystallographic data for compound 8 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 713233. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
22. Crystallographic data for compound 9 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712034. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
23. Crystallographic data for compound 10 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712035. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
24. Crystallographic data for compound 11 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712036. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).
25. Crystallographic data for compound 15 has been deposited with the Cambridge Crystallographic Data Centre as supplementary publication No.CCDC 712033. Copies of the data can be obtained, free of charge, on application to the Director, CCDC (e-mail: deposit@ccdc.cam.ac.uk).