Adherence to osteoporosis medications after patient and physician brief education: Post Hoc analysis of a randomized controlled trial

American Journal of Managed Care

Volumn 15, Issue 7, 2009, Pages 417-424

  Shu, Aimee Der Huey ^a,b   Stedman, Margaret R ^a   Polinski, Jennifer M ^a   Jan, Saira A ^c   Patel, Minal ^c   Truppo, Colleen ^c,e   Breiner, Laura ^c,f   Chen, Ya Ting ^d   Weiss, Thomas W ^d   Solomon, Daniel H ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b New York Presbyterian Hospital Columbia University Medical Center   (United States)

^c HORIZON BLUE CROSS BLUE SHIELD OF NEW JERSEY   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

^e Care Management International   (United States)

^f NYC Department of Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALENDRONIC ACID; CALCITONIN; ESTROGEN; PARATHYROID HORMONE[1-34]; RISEDRONIC ACID;

ADULT; AGED; ARTICLE; BONE DENSITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OSTEOPOROSIS; OUTCOME ASSESSMENT; PATIENT COMPLIANCE; PATIENT EDUCATION; PRIMARY MEDICAL CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; TELECONSULTATION;

AGED; BONE DENSITY CONSERVATION AGENTS; CONFIDENCE INTERVALS; DIPHOSPHONATES; EDUCATION, MEDICAL, CONTINUING; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; OSTEOPOROSIS; PATIENT EDUCATION AS TOPIC; RISK; TIME FACTORS; UNITED STATES;

EID: 67650828616     PISSN: 10880224     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Caro JJ, Ishak KJ, Huybrechts KF, Raggio G, Naujoks C. The impact of compliance with osteoporosis therapy on fracture rates in actual practice. Osteoporos Int. 2004;15(12):1003-1008. (Pubitemid 40064656)
2. McCombs JS, Thiebaud P, McLaughlin-Miley C, Shi J. Compliance with drug therapies for the treatment and prevention of osteoporosis. Maturitas. 2004;48(3):271-287. (Pubitemid 38781153)
3. Solomon DH, Avom J, Katz JN, et al. Compliance with osteoporosis medications. Arch Intern Med. 2005;165(20):2414-2419.
4. Emkey RD, Ettinger M. Improving compliance and persistence with bisphosphonate therapy for osteoporosis. Am J Med. 2006;119(4) (suppl 1):S18-S24.
5. McDonald HP, Garg AX, Haynes RB. Interventions to enhance patient adherence to medication prescriptions: scientific review [published correction appears in JAMA. 2003;289(24):3242]. JAMA. 2002;288(22):2868-2879.
6. Osterberg L, BlaschkeT. Adherence to medication. N Engl J Med. 2005;353(5):487-497.
7. Cramer JA, Silverman S. Persistence with bisphosphonate treatment for osteoporosis: finding the root of the problem. Am J Med. 2006;119(4)(suppl 1):S12-S17.
8. Gold DT, McClung B. Approaches to patient education: emphasizing the long-term value of compliance and persistence. Am J Med. 2006;119(4)(suppl 1):S32-S37.
9. Reginster JY. Adherence and persistence: impact on outcomes and health care resources. Bone. 2006;38(2)(suppl 2):S18-S21. (Pubitemid 43177168)
10. Clowes JA, Peel NF, Eastell R. The impact of monitoring on adherence and persistence with antiresorptive treatment for postmenopausal osteoporosis: a randomized controlled trial. J Clin Endocrinol Metab. 2004;89(3):1117-1123. (Pubitemid 38368399)
11. Cuddihy MT, Amadio PC, Gabriel SE, Pankratz VS, Kurland RL, Melton LJ III. A prospective clinical practice intervention to improve osteoporosis management following distal forearm fracture. Osteoporos Int. 2004;15(9):695-700.
12. Solomon DH, Polinski JM, Stedman M, et al. Improving care of patients at-risk for osteoporosis: a randomized controlled trial. J Gen Intern Med. 2007;22(3):362-367. (Pubitemid 46941242)
13. Lagakos SW. The challenge of subgroup analyses: reporting without distorting [published correction appears in N Engl J Med. 2006;355(5):533]. N Engl J Med. 2006;354(16):1667-1669.
14. Avom J, Soumerai SB. Improving drug-therapy decisions through educational outreach: a randomized controlled trial of academically based "detailing." N Engl J Med. 1983;308(24):1457-1463.
15. Polinski JM, Brookhart MA, Katz JN, et al. Educational outreach (academic detailing) regarding osteoporosis in primary care. Pharmacoepidemiol Drug Saf. 2005;14(12):843-850.
16. Soumerai SB, Avom J. Principles of educational outreach ('academic detailing') to improve clinical decision making. JAMA. 1990;263(4):549-556.
17. Polinski JM, Patrick A. Truppo C, et al. Interactive voice response telephone calls to enhance bone mineral density testing. Am J Manag Care. 2006;12(6):321-325. (Pubitemid 43911219)
18. Cramer JA, Amonkar MM, Hebbom A, Altman R. Compliance and persistence with bisphosphonate dosing regimens among women with postmenopausal osteoporosis. Curr Med Res Opin. 2005;21(9):1453-1460. (Pubitemid 41368578)
19. Recker RR, Gallagher R, MacCosbe PE. Effect of dosing frequency on bisphosphonate medication adherence in a large longitudinal cohort of women. Mayo Clin Proc. 2005;80(7):856-861. (Pubitemid 40911458)
20. Reginster JY, Rabenda V, Neuprez A. Adherence, patient preference and dosing frequency: understanding the relationship. Bone. 2006;38(4)(suppl 1):S2-S6.
21. Sikka R, Xia F, Aubert RE. Estimating medication persistency using administrative claims data. Am J Manag Care. 2005;11(7):449-457. (Pubitemid 41022729)
22. Hubbard AE, Van der Laan MJ, Enanoria W, Colford JM Jr. Nonparametric survival estimation when death is reported with delay. Lifetime Data Anal. 2000;6(3):237-250.
23. Huybrechts KF, Ishak KJ, Caro JJ. Assessment of compliance with osteoporosis treatment and its consequences in a managed care population. Bone. 2006;38(6):922-928.
24. Siris ES, Harris ST, Rosen CJ, et al. Adherence to bisphosphonate therapy and fracture rates in osteoporotic women: relationship to vertebral and nonvertebral fractures from 2 US claims databases. Mayo Clin Proc. 2006;81(8):1013-1022.
25. White HD. Adherence and outcomes: it's more than taking the pills. Lancet. 2005;366(9502):1989-1991.
26. Penning-van Beest FJ, Goettsch WG, Erkens JA, Herings RM. Determinants of persistence with bisphosphonates: a study in women with postmenopausal osteoporosis. Clin Ther. 2006;28(2):236-242. (Pubitemid 44287822)
27. Belcon MC, Haynes RB, Tugwell P. A critical review of compliance studies in rheumatoid arthritis. Arthritis Rheum. 1984;27(11):1227-1233. (Pubitemid 15212135)
28. Nielsen D, Ryg J, Nissen N, Nielsen W, Knold B, Brixen K. Multidisciplinary group education increases knowledge on osteoporosis: a randomized trial. Scand J Public Health. 2008;36(4):346-352. (Pubitemid 351796237)
29. Silverman SL, Gold DT, Cramer JA. Reduced fracture rates observed only in patients with proper persistence and compliance with bisphosphonate therapies. South Med J. 2007;100(12): 1214-1218.
30. Kothawala P, Badamgarav E, Ryu S, Miller RM, Halbert RJ. Systematic review and meta-analysis of real-world adherence to drug therapy for osteoporosis. Mayo Clin Proc. 2007;82(12):1493-1501. (Pubitemid 350211697)