Analysis of treatments and deceaded cases of severe adverse drug reactions - Analysis of 46 cases of Stevens-Johnson syndrome and toxic epidermal necrolysis

Japanese Journal of Allergology

Volumn 58, Issue 5, 2009, Pages 537-547

  Yamane, Yumiko ^a   Aihara, Michiko ^a   Tatewaki, Satoko ^a   Matsukura, Setsuko ^b   Kanbara, Takeshi ^b   Yamakawa, Yuko ^b   Ikezawa, Zenro ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

^b YOKOHAMA CITY UNIVERSITY MEDICAL CENTER   (Japan)

Author keywords

Prognosis; Stevens Johnson syndrome; Toxic epidermal necrolysis; Treatment

Indexed keywords

AMPHOTERICIN B; BETAMETHASONE; CEFDITOREN PIVOXIL; CORTICOSTEROID; CYCLOSPORIN A; HERBACEOUS AGENT; IMMUNOGLOBULIN; METHYLPREDNISOLONE; NONSTEROID ANTIINFLAMMATORY AGENT; OMEPRAZOLE; PARACETAMOL; PHENOBARBITAL; PREDNISOLONE; VALPROIC ACID; GLUCOCORTICOID;

ACUTE RESPIRATORY TRACT DISEASE; ADULT; AGED; ARTICLE; CAUSE OF DEATH; CLINICAL ARTICLE; DEATH; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; FEMALE; HUMAN; MALE; MORTALITY; OUTCOME ASSESSMENT; PLASMAPHERESIS; RASH; SEPSIS; STEVENS JOHNSON SYNDROME; TOXIC EPIDERMAL NECROLYSIS; TREATMENT OUTCOME; DRUG PULSE THERAPY; MIDDLE AGED; PROGNOSIS;

ADULT; AGED; AGED, 80 AND OVER; EPIDERMAL NECROLYSIS, TOXIC; FEMALE; GLUCOCORTICOIDS; HUMANS; IMMUNOGLOBULINS; MALE; METHYLPREDNISOLONE; MIDDLE AGED; PLASMA EXCHANGE; PROGNOSIS; PULSE THERAPY, DRUG; STEVENS-JOHNSON SYNDROME;

EID: 67650822982     PISSN: 00214884     EISSN: 13477935     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Stevens AM, Johnson FC. A new eruptive fever associated with stomatitis and opthalmia. Am J Dis Child 1922; 24: 526-533
2. Lyell A. Toxic epidermal necrolysis: an eruption resembling scalding of the skin. Br J Dermatol 1956; 68: 355-361
3. Bastuji-Garin S, Fouchard N, Bertocchi M, Roujeau JC, Revuz J, Wolkenstein P. SCORTEN: A severity-of-illness score for toxic epidermal necrolysis. J Invest Dermatol 2000; 115: 149-153 (Pubitemid 30637181)
4. Guégan S, Bastuji-Garin S, Poszepczynska-Guigné E, Roujeau JC, Revuz J. Performance of the SCORTEN during the first five days of hospitalization to predict the prognosis of epidermal necrolysis. J Invest Dermatol 2006; 126: 272-276 (Pubitemid 43323160)
5. Hague JS, Goulding JM, Long TM, Gee BC. Respiratory involvement in toxic epidermal necrolysis portends a poor prognosis that may not be reflected in SCORTEN. Br J Dermatol 2007; 157: 1294-1296 (Pubitemid 350115695)
6. Schneck J, Fagot J, Sekula P, Sassolas B, Roujeau J, Mockenhaupt M. Effects of treatments on the mortality of Stevens-Johnson syndrome and toxic epidermal necrolysis: A retrospective study on patients included in the prospective EuroSCAR Study. J Am Acad Dermatol 2008; 58: 33-40. (Pubitemid 350298143)
7. Paul C, Wolkenstein P, Adle H, Wechsler J, Garchon HJ, Revuz J, et al. Apoptosis as a mechanism of keratinocyte death in toxic epidermal necrolysis. Br J Dermatol 1996; 134: 710-714 (Pubitemid 26120740)
8. Caproni M, Torchia D, Schincaglia E, Volpi W, Frezzolini A, Schena D, et al. Expression of cytokines and chemokine receptors in the cutaneous lesions of erythema multiforme and Stevens-Johnson syndrome/toxic epidermal necrolysis. Br J Dermatol 2006; 155: 722-728 (Pubitemid 44352552)
9. Viard I, Wehrli P, Bullani R, Schneider P, Holler N, Salomon D, et al. Inhibition of toxic epidermal necrolysis by blockade of CD95 with human intravenous immunoglobulin. Science 1998; 282: 490-493 (Pubitemid 28483679)
10. Bamichas G, Natse T, Christidou F, Stangou M, Karagianni A, Koukourikos S, et al. Plasma exchange in patients with toxic epidermal necrolysis. Ther Apher 2002; 6: 225-228 (Pubitemid 34753566)