Interference from heterophilic antibodies in TSH assays

Annals of Clinical Biochemistry

Volumn 46, Issue 4, 2009, Pages 345-346

  Halsall, D J ^a   English, E ^a   Chatterjee, V K ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; HETEROPHILE ANTIBODY; THYROTROPIN;

CROSS LINKING; FALSE NEGATIVE RESULT; GEL FILTRATION CHROMATOGRAPHY; HORMONE DETERMINATION; HUMAN; IMMUNOREACTIVITY; LETTER; NONHUMAN; PRIORITY JOURNAL;

ANTIBODIES, HETEROPHILE; BIOLOGICAL ASSAY; HUMANS; IMMUNOASSAY; THYROTROPIN;

EID: 67650806476     PISSN: 00045632     EISSN: 00045632     Source Type: Journal    
DOI: 10.1258/acb.2009.009024     Document Type: Letter

References (5)

1. Ross HA, Menheere PP, Thomas CM, Mudde AH, Kouwenberg M, Wolffenbuttel BH. Interference from heterophilic antibodies in seven current TSH assays. Ann Clin Biochem 2008;45:616
2. Kaplan IV, Levinson SS. When is a heterophile antibody not a heterophile antibody? When it is an antibody against a specific immunogen. Clin Chem 1999;45:616-618 (Pubitemid 29220321)
3. Despres N, Grant AM. Antibody interference in thyroid assays: a potential for clinical misinformation. Clin Chem 1998;44:440-454 (Pubitemid 28141337)
4. Halsall DJ, Fahie-Wilson MN, Hall SK, et al. Macro thyrotropin-IgG complex causes factitious increases in thyroid stimulating hormone screening tests in a neonate and mother. Clin Chem 2006;52:1968-1969 (Pubitemid 44470708)
5. English E, Cartwright D, Barker P, et al. Different results for macro-TSH using different assays: a possible mechanism. Ann Clin Biochem 2008;45(Suppl 1):108