Re: Insulin, insulin-like growth factor-i, and risk of breast cancer in postmenopausal women

Journal of the National Cancer Institute

Volumn 101, Issue 14, 2009, Pages 1030-1031

  Vigneri, Riccardo ^a,b   Frasca, Francesco ^a   Sciacca, Laura ^a   Vigneri, Paolo ^a   Frittitta, Lucia ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b GARIBALDI HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH FACTOR; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR ISOFORM A; SOMATOMEDIN B; SOMATOMEDIN C; UNCLASSIFIED DRUG;

BREAST CANCER; BREAST CELL; CANCER CELL; CANCER GROWTH; CANCER RISK; CELL PROLIFERATION; DIET RESTRICTION; DISEASE FREE SURVIVAL; FEMALE; FIBROBLAST; GENE OVEREXPRESSION; HUMAN; HYPERINSULINEMIA; IN VITRO STUDY; IN VIVO STUDY; INSULIN BLOOD LEVEL; LETTER; LYMPH NODE BIOPSY; MITOGENESIS; PHENOTYPE; POSTMENOPAUSE; PRIORITY JOURNAL; RISK FACTOR; TUMOR PROMOTION;

AGED; ANIMALS; BREAST NEOPLASMS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYPERINSULINISM; INSULIN; INSULIN-LIKE GROWTH FACTOR I; MICE; MIDDLE AGED; POSTMENOPAUSE; RISK ASSESSMENT; RISK FACTORS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 67650796185     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djp158     Document Type: Letter

References (7)

1. Gunter MJ , Hoover DR , Yu H , et al. Insulin, insulin-like growth factor-1, and risk of breast cancer in postmenopausal women. J Natl Cancer Inst. 2009 ; 101 ( 1 ): 48 -60.
2. Giorgino F , Belfi ore A , Milazzo G , et al. Overexpression of insulin receptors in fi broblast and ovary cells induces a ligand-mediated transformed phenotype. Mol Endocrinol. 1991 ; 5 ( 3 ): 452 -459.
3. Frittitta L , Vigneri R , Stampfer MR , Goldfi ne ID. Insulin receptor overexpression in 184B5 human mammary epithelial cells induces a ligand-dependent transformed phenotype. J Cell Biochem. 1995 ; 57 ( 4 ): 666 -669.
4. Papa V , Pezzino V , Costantino A. Elevated insulin receptor content in human breast cancer. J Clin Invest. 1990 ; 86 ( 5 ): 1503 -1510.
5. Mathieu MC , Clark GM , Allred DG , Goldfi ne ID , Vigneri R. Insulin receptor expression and clinical outcome in node-negative breast cancer. Proc Assoc Am Physicians. 1997 ; 109 ( 6 ): 565 -571.
6. Sciacca L , Costantino A , Pandini G , et al. Insulin receptor activation by IGF-II in breast cancers: evidence for a new autocrine/ paracrine mechanism. Oncogene. 1999 ; 18 ( 15 ): 2471 -2479.
7. Pandini G , Vigneri R , Costantino A , et al. Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/ IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. Clin Cancer Res. 1999 ; 5 ( 17 ): 1935 -1944.