Expression of cytokeratin 17 mRNA in oral squamous cell carcinoma cells obtained by brush biopsy: Preliminary results

Journal of Oral Pathology and Medicine

Volumn 38, Issue 6, 2009, Pages 530-534

  Toyoshima, T ^a,b   Koch, F ^a   Kaemmerer, P ^a   Vairaktaris, E ^c   Al Nawas, B ^a   Wagner, W ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Brush biopsy; Cytokeratin; Diagnostic marker; Oral squamous cell carcinoma; SYBR green real time quantitative reverse transcriptase polymerase chain reaction

Indexed keywords

COMPLEMENTARY DNA; CYTOKERATIN 17; CYTOKERATIN 19; CYTOKERATIN 20; MESSENGER RNA;

ARTICLE; BIOPSY; BRUSH BIOPSY; CANCER STAGING; CARCINOMA CELL; CELL DIFFERENTIATION; CERVICAL LYMPH NODE; CONTROLLED STUDY; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MOUTH CARCINOMA; MOUTH MUCOSA; MUCOSA CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SQUAMOUS CELL CARCINOMA;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CYTODIAGNOSIS; GENE EXPRESSION REGULATION; HUMANS; KERATIN-17; KERATIN-19; KERATIN-20; LYMPHATIC METASTASIS; MOUTH MUCOSA; MOUTH NEOPLASMS; NEOPLASM STAGING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL;

EID: 67650763331     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2009.00748.x     Document Type: Article

References (21)

1. Sciubba JJ. Improving detection of precancerous and cancerous oral lesions. Computer-assisted analysis of the oral brush biopsy. U.S. Collaborative OralCDx Study Group. J Am Dent Assoc 1999 130 : 1445 57.
2. Temam S, Benard J, Dugas C, et al. Molecular detection of early-stage laryngopharyngeal squamous cell carcinomas. Clin Cancer Res 2005 11 : 2547 51.
3. Steinau M, Lee DR, Rajeevan MS, et al. Gene expression profile of cervical tissue compared to exfoliated cells: impact on biomarker discovery. BMC Genomics 2005 6 : 64.
4. Spivack SD, Hurteau GJ, Jain R, et al. Gene-environment interaction signatures by quantitative mRNA profiling in exfoliated buccal mucosal cells. Cancer Res 2004 64 : 6805 13.
5. Smith RV, Schlecht NF, Childs G, et al. Pilot study of mucosal genetic differences in early smokers and nonsmokers. Laryngoscope 2006 116 : 1375 9.
6. Moll R, Krepler R, Franke WW. Complex cytokeratin polypeptide patterns observed in certain human carcinomas. Differentiation 1983 23 : 256 69.
7. Lane EB, Alexander CM. Use of keratin antibodies in tumor diagnosis. Semin Cancer Biol 1990 1 : 165 79.
8. Chu PG, Weiss LM. Keratin expression in human tissues and neoplasms. Histopathology 2002 40 : 403 39.
9. Cohen-Kerem R, Madah W, Sabo E, et al. Cytokeratin-17 as a potential marker for squamous cell carcinoma of the larynx. Ann Otol Rhinol Laryngol 2004 113 : 821 7.
10. Van De Rijn M, Perou CM, Tibshirani R, et al. Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am J Pathol 2002 161 : 1991 6.
11. Toyoshima T, Vairaktaris E, Nkenke E, et al. Cytokeratin 17 mRNA expression has potential for diagnostic marker of oral squamous cell carcinoma. J Cancer Res Clin Oncol 2008 134 : 515 21.
12. Zhong LP, Chen WT, Zhang CP, et al. Increased CK19 expression correlated with pathologic differentiation grade and prognosis in oral squamous cell carcinoma patients. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007 104 : 377 84.
13. Remmerbach TW, Brinckmann UG, Hemprich A, et al. PCR detection of human papillomavirus of the mucosa: comparison between MY09/11 and GP5+/6+ primer sets. J Clin Virol 2004 30 : 302 8.
14. Schwartz JL, Panda S, Beam C, et al. RNA from brush oral cytology to measure squamous cell carcinoma gene expression. J Oral Pathol Med 2008 37 : 70 7.
15. Driemel O, Kosmehl H, Rosenhahn J, et al. Expression analysis of extracellular matrix components in brush biopsies of oral lesions. Anticancer Res 2007 27 : 1565 70.
16. Carrilho C, Alberto M, Buane L, et al. Keratins 8, 10, 13, and 17 are useful markers in the diagnosis of human cervix carcinomas. Hum Pathol 2004 35 : 546 51.
17. Maddox P, Sasieni P, Szarewski A, et al. Differential expression of keratins 10, 17, and 19 in normal cervical epithelium, cervical intraepithelial neoplasia, and cervical carcinoma. J Clin Pathol 1999 52 : 41 6.
18. Martens J, Baars J, Smedts F, et al. Can keratin 8 and 17 immunohistochemistry be of diagnostic value in cervical cytology? A feasibility study Cancer 1999 87 : 87 92. (Pubitemid 29204905)
19. Ikeda K, Tate G, Suzuki T, et al. Coordinate expression of cytokeratin 8 and cytokeratin 17 immunohistochemical staining in cervical intraepithelial neoplasia and cervical squamous cell carcinoma: an immunohistochemical analysis and review of the literature. Gynecol Oncol 2008 108 : 598 602.
20. Kawamata H, Uchida D, Nakashiro K, et al. Haematogenous cytokeratin 20 mRNA as a predictive marker for recurrence in oral cancer patients. Br J Cancer 1999 80 : 448 52.
21. Christoph F, Weikert S, Wolff I, et al. Urinary cytokeratin 20 mRNA expression has the potential to predict recurrence in superficial transitional cell carcinoma of the bladder. Cancer Lett 2007 245 : 121 6.