Comparative in vivo and in vitro analyses of putative virulence factors of Burkholderia pseudomallei using lipopolysaccharide, capsule and flagellin mutants

FEMS Immunology and Medical Microbiology

Volumn 56, Issue 3, 2009, Pages 253-259

  Wikraiphat, Chanthiwa ^a   Charoensap, Jaruek ^a   Utaisincharoen, Pongsak ^a   Wongratanacheewin, Surasakdi ^b   Taweechaisupapong, Suwimol ^c   Woods, Donald E ^d   Bolscher, Jan G M ^e   Sirisinha, Stitaya ^a  

^a Mahidol University ^*  (Thailand)

^b KHON KAEN UNIVERSITY   (Thailand)

^c KHON KAEN UNIVERSITY   (Thailand)

^d Health Sciences Centre Calgary   (Canada)

^e VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

Burkholderia pseudomallei; Capsule; Flagella; Lipopolysaccharide; Macrophage; Polymorphonuclear cell

Indexed keywords

ANTIBIOTIC AGENT; BACTERIUM LIPOPOLYSACCHARIDE; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; FLAGELLIN; HISTATIN 5; LACTOFERRIN; MUTANT PROTEIN; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL MEMBRANE; BACTERIAL VIRULENCE; BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; COMPARATIVE STUDY; CONTROLLED STUDY; GRAM NEGATIVE INFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL CAPSULES; BACTERIAL PROTEINS; BLOOD BACTERICIDAL ACTIVITY; BURKHOLDERIA PSEUDOMALLEI; FLAGELLIN; GENE KNOCKOUT TECHNIQUES; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; MICROBIAL VIABILITY; MUTAGENESIS, INSERTIONAL; NEUTROPHILS; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SURVIVAL ANALYSIS; VIRULENCE; VIRULENCE FACTORS;

EID: 67650760368     PISSN: 09288244     EISSN: 1574695X     Source Type: Journal    
DOI: 10.1111/j.1574-695X.2009.00574.x     Document Type: Article

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