Pyripyropenes, fungal sesquiterpenes conjugated with α-pyrone and pyridine moieties, exhibits anti-angiogenic activity against human umbilical vein endothelial cells

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 7, 2009, Pages 1261-1265

  Hayashi, Asami ^a   Arai, Masayoshi ^a   Fujita, Mayumi ^a   Kobayashi, Motomasa ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

Anti angiogenic effect; Human umbilical vein endothelial cell; Marine derived fungus; Migration; Pyripyropene; Tubular formation

Indexed keywords

2,2 DIMETHYL N (2,4,6 TRIMETHOXYPHENYL)DODECANAMIDE; CYTOSTATIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; PYRIPYROPENE A; PYRIPYROPENE DERIVATIVE; SESQUITERPENE DERIVATIVE; SYNAPTOPHYSIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL CELL; ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASPERGILLUS; CANCER INHIBITION; CELL MIGRATION; CELL STRAIN KB; CONTROLLED STUDY; DRUG SELECTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANGIOGENESIS INHIBITORS; ASPERGILLUS; CELL LINE; CELL MOVEMENT; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR STRUCTURE; NEOVASCULARIZATION, PATHOLOGIC; PYRIDINES; PYRONES; RECOMBINANT PROTEINS; SESQUITERPENES; STEROL O-ACYLTRANSFERASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67650759754     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1261     Document Type: Article

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