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Volumn 877, Issue 24, 2009, Pages 2566-2570
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High-performance liquid chromatography-tandem mass spectrometry for the determination of pidotimod in human plasma and its application to a pharmacokinetic study
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Author keywords
HPLC MS MS; Human plasma; Pharmacokinetic study; Pidotimod
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Indexed keywords
CLINICAL PHARMACOKINETICS;
CONCENTRATION RANGES;
DIPHENHYDRAMINE;
HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY;
HPLC-MS/MS;
HUMAN PLASMA;
HUMAN PLASMAS;
INTERNAL STANDARDS;
LINEAR CALIBRATION CURVE;
LOWER LIMIT OF QUANTIFICATIONS;
METHANOL-WATER;
MOBILE PHASE;
MULTIPLE-REACTION MONITORING MODES;
ORAL ADMINISTRATION;
PHARMACOKINETIC STUDIES;
PHARMACOKINETIC STUDY;
PIDOTIMOD;
PLASMA SAMPLES;
PROTEIN PRECIPITATION;
RELATIVE ERRORS;
RELATIVE STANDARD DEVIATIONS;
SAMPLE PRETREATMENT;
TRIPLE QUADRUPOLE;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
ELECTROSPRAY IONIZATION;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETERS;
MASS SPECTROMETRY;
METHANOL;
ORGANIC ACIDS;
PHARMACOKINETICS;
PLASMA (HUMAN);
PLASMAS;
PRECIPITATION (CHEMICAL);
QUALITY ASSURANCE;
QUALITY CONTROL;
QUALITY FUNCTION DEPLOYMENT;
TOTAL QUALITY MANAGEMENT;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
DIPHENHYDRAMINE;
METHANOL;
PIDOTIMOD;
WATER;
ARTICLE;
BLOOD SAMPLING;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG ELIMINATION;
DRUG ISOLATION;
DRUG STABILITY;
DRUG STRUCTURE;
ELECTROSPRAY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
MAXIMUM PLASMA CONCENTRATION;
PRIORITY JOURNAL;
QUALITY CONTROL;
TANDEM MASS SPECTROMETRY;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
HUMANS;
IMMUNOLOGIC FACTORS;
MALE;
PYRROLIDONECARBOXYLIC ACID;
TANDEM MASS SPECTROMETRY;
THIAZOLIDINES;
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EID: 67650753253
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2009.06.038 Document Type: Article |
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Times cited : (11)
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References (10)
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