Expression of RNA CCUG repeats dysregulates translation and degradation of proteins in myotonic dystrophy 2 patients

American Journal of Pathology

Volumn 175, Issue 2, 2009, Pages 748-762

  Salisbury, Elizabeth ^a   Schoser, Benedikt ^b   Schneider Gold, Christiane ^c   Wang, Guo Li ^a   Huichalaf, Claudia ^a,f   Jin, Bingwen ^a   Sirito, Mario ^d   Sarkar, Partha ^e   Krahe, Ralf ^d   Timchenko, Nikolai A ^a   Timchenko, Lubov T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF MUNICH   (Germany)

^c ST JOSEF HOSPITAL   (Germany)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e University of Texas Medical Branch School of Medicine   (United States)

^f SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CUG TRIPLET REPEAT RNA BINDING PROTEIN 1; CYTOPLASM PROTEIN; INITIATION FACTOR; MULTIPROTEIN COMPLEX; PROTEASOME; RNA; RNA BINDING PROTEIN; TRANSLATION INITIATION FACTOR EIF2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE OVEREXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MOUSE; MUSCLE BIOPSY; MYOBLAST; MYOTONIC DYSTROPHY; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN ISOLATION; PROTEIN METABOLISM; PROTEIN PURIFICATION; RNA TRANSLATION; TRANSLATION INITIATION;

EID: 67650751240     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.2353/ajpath.2009.090047     Document Type: Article

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