Novel lead structures for p38 MAP kinase via FieldScreen virtual screening

Journal of Medicinal Chemistry

Volumn 52, Issue 14, 2009, Pages 4200-4209

  Cheeseright, Timothy J ^a   Holm, Melanie ^b   Lehmann, Frank ^b   Luik, Sabine ^b   Gottert, Marcia ^b   Melville, James L ^a   Laufer, Stefan ^b  

^a Cresset BioMolecular Discovery Ltd   (United Kingdom)

^b UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINO 5 (2,4 DICHLOROPHENYL) 4H 1,2,4 TRIAZOLE 3 THIOL; LIGAND; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE P38 INHIBITOR; THIADIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONFORMATION; DRUG SCREENING; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; INFLAMMATION; MOLECULAR MODEL; STRUCTURE ACTIVITY RELATION;

DRUG EVALUATION, PRECLINICAL; LIGANDS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP; THIADIAZOLES;

EID: 67650720911     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm801399r     Document Type: Article

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