-
2
-
-
0028929803
-
Angiogenesis in cancer, vascular, rheumatoid and other disease
-
Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1 (1995) 27-31
-
(1995)
Nat Med
, vol.1
, pp. 27-31
-
-
Folkman, J.1
-
3
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D., and Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86 (1996) 353-364
-
(1996)
Cell
, vol.86
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
4
-
-
0030952289
-
Mechanisms of angiogenesis
-
Risau W. Mechanisms of angiogenesis. Nature 386 (1997) 671-674
-
(1997)
Nature
, vol.386
, pp. 671-674
-
-
Risau, W.1
-
5
-
-
0034648793
-
Vascular-specific growth factors and blood vessel formation
-
Yancopoulos G.D., Davis S., Gale N.W., et al. Vascular-specific growth factors and blood vessel formation. Nature 407 (2000) 242-248
-
(2000)
Nature
, vol.407
, pp. 242-248
-
-
Yancopoulos, G.D.1
Davis, S.2
Gale, N.W.3
-
7
-
-
0343920277
-
Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
-
Carmeliet P., Ferreira V., Breier G., et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 380 (1996) 435-439
-
(1996)
Nature
, vol.380
, pp. 435-439
-
-
Carmeliet, P.1
Ferreira, V.2
Breier, G.3
-
9
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P., and Jain R.K. Angiogenesis in cancer and other diseases. Nature 407 (2000) 249-257
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
10
-
-
84959830787
-
Vascular reactions of normal and malignant tissues in vivo. I. Vascular reactions of mice to wounds and to normal and neoplastic transplants
-
Algire G.H., and Chalkley H.W. Vascular reactions of normal and malignant tissues in vivo. I. Vascular reactions of mice to wounds and to normal and neoplastic transplants. J Natl Cancer Inst USA 6 (1945) 73-85
-
(1945)
J Natl Cancer Inst USA
, vol.6
, pp. 73-85
-
-
Algire, G.H.1
Chalkley, H.W.2
-
11
-
-
0001148826
-
The growth of malignant disease in man and the lower animals with special reference to the vascular system
-
Goldman E. The growth of malignant disease in man and the lower animals with special reference to the vascular system. Lancet 2 (1907) 1236-1240
-
(1907)
Lancet
, vol.2
, pp. 1236-1240
-
-
Goldman, E.1
-
12
-
-
0000912662
-
Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber
-
Ide A.G., Baker N.H., and Warren S.L. Vascularization of the Brown-Pearce rabbit epithelioma transplant as seen in the transparent ear chamber. Am J Radiol 42 (1939) 891-899
-
(1939)
Am J Radiol
, vol.42
, pp. 891-899
-
-
Ide, A.G.1
Baker, N.H.2
Warren, S.L.3
-
13
-
-
0013943005
-
Tumor behavior in isolated perfused organs: in vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segment
-
Folkman J., Cole P., and Zimmerman S. Tumor behavior in isolated perfused organs: in vitro growth and metastases of biopsy material in rabbit thyroid and canine intestinal segment. Ann Surg 164 (1966) 491-502
-
(1966)
Ann Surg
, vol.164
, pp. 491-502
-
-
Folkman, J.1
Cole, P.2
Zimmerman, S.3
-
14
-
-
0025141337
-
What is the evidence that tumors are angiogenesis dependent?
-
Folkman J. What is the evidence that tumors are angiogenesis dependent?. J Natl Cancer Inst 82 (1990) 4-6
-
(1990)
J Natl Cancer Inst
, vol.82
, pp. 4-6
-
-
Folkman, J.1
-
15
-
-
0034265986
-
Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: a quantitative multi-parameter analysis
-
Rijken P.F., Bernsen H.J., Peters J.P., et al. Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: a quantitative multi-parameter analysis. Int J Radiat Oncol Biol Phys 48 (2000) 571-582
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 571-582
-
-
Rijken, P.F.1
Bernsen, H.J.2
Peters, J.P.3
-
16
-
-
0015982084
-
Tumor growth and neovascularization: an experimental model using the rabbit cornea
-
Gimbrone Jr. M.A., Cotran R.S., Leapman S.B., et al. Tumor growth and neovascularization: an experimental model using the rabbit cornea. J Natl Cancer Inst 52 (1974) 413-427
-
(1974)
J Natl Cancer Inst
, vol.52
, pp. 413-427
-
-
Gimbrone Jr., M.A.1
Cotran, R.S.2
Leapman, S.B.3
-
17
-
-
0015380016
-
Tumor dormancy in vivo by prevention of neovascularization
-
Gimbrone Jr. M.A., Leapman S.B., Cotran R.S., et al. Tumor dormancy in vivo by prevention of neovascularization. J Exp Med 136 (1972) 261-276
-
(1972)
J Exp Med
, vol.136
, pp. 261-276
-
-
Gimbrone Jr., M.A.1
Leapman, S.B.2
Cotran, R.S.3
-
18
-
-
0017341618
-
Avascular and vascular phases of tumour growth in the chick embryo
-
Knighton D., Ausprunk D., Tapper D., et al. Avascular and vascular phases of tumour growth in the chick embryo. Br J Cancer 35 (1977) 347-356
-
(1977)
Br J Cancer
, vol.35
, pp. 347-356
-
-
Knighton, D.1
Ausprunk, D.2
Tapper, D.3
-
19
-
-
0014833051
-
The blood supply of experimental liver metastases. II. A microcirculatory study of the normal and tumor vessels of the liver with the use of perfused silicone rubber
-
Lien W.M., and Ackerman N.B. The blood supply of experimental liver metastases. II. A microcirculatory study of the normal and tumor vessels of the liver with the use of perfused silicone rubber. Surgery 68 (1970) 334-340
-
(1970)
Surgery
, vol.68
, pp. 334-340
-
-
Lien, W.M.1
Ackerman, N.B.2
-
20
-
-
0023243816
-
Tumours acquire their vasculature by vessel incorporation, not vessel ingrowth
-
Thompson W.D., Shiach K.J., Fraser R.A., et al. Tumours acquire their vasculature by vessel incorporation, not vessel ingrowth. J Pathol 151 (1987) 323-332
-
(1987)
J Pathol
, vol.151
, pp. 323-332
-
-
Thompson, W.D.1
Shiach, K.J.2
Fraser, R.A.3
-
21
-
-
0014365361
-
Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy
-
Ehrmann R.L., and Knoth M. Choriocarcinoma. Transfilter stimulation of vasoproliferation in the hamster cheek pouch. Studied by light and electron microscopy. J Natl Cancer Inst 41 (1968) 1329-1341
-
(1968)
J Natl Cancer Inst
, vol.41
, pp. 1329-1341
-
-
Ehrmann, R.L.1
Knoth, M.2
-
22
-
-
0014304893
-
Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique
-
Greenblatt M., and Shubi P. Tumor angiogenesis: transfilter diffusion studies in the hamster by the transparent chamber technique. J Natl Cancer Inst 41 (1968) 111-124
-
(1968)
J Natl Cancer Inst
, vol.41
, pp. 111-124
-
-
Greenblatt, M.1
Shubi, P.2
-
23
-
-
85013312416
-
Tumor angiogenesis: therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 285 (1971) 1182-1186
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
24
-
-
0018094041
-
Angiogenesis and oncogenesis
-
Gullino P.M. Angiogenesis and oncogenesis. J Natl Cancer Inst 61 (1978) 639-643
-
(1978)
J Natl Cancer Inst
, vol.61
, pp. 639-643
-
-
Gullino, P.M.1
-
25
-
-
0028060380
-
Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1
-
Dameron K.M., Volpert O.V., Tainsky M.A., et al. Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1. Science 265 (1994) 1582-1584
-
(1994)
Science
, vol.265
, pp. 1582-1584
-
-
Dameron, K.M.1
Volpert, O.V.2
Tainsky, M.A.3
-
26
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
Maxwell P.H., Wiesener M.S., Chang G.W., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature 399 (1999) 271-275
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
-
28
-
-
0030893967
-
Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity
-
Volpert O.V., Dameron K.M., and Bouck N. Sequential development of an angiogenic phenotype by human fibroblasts progressing to tumorigenicity. Oncogene 14 (1997) 1495-1502
-
(1997)
Oncogene
, vol.14
, pp. 1495-1502
-
-
Volpert, O.V.1
Dameron, K.M.2
Bouck, N.3
-
30
-
-
0029782859
-
Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor
-
Cheng S.Y., Huang H.J., Nagane M., et al. Suppression of glioblastoma angiogenicity and tumorigenicity by inhibition of endogenous expression of vascular endothelial growth factor. Proc Natl Acad Sci USA 93 (1996) 8502-8507
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8502-8507
-
-
Cheng, S.Y.1
Huang, H.J.2
Nagane, M.3
-
31
-
-
0028797077
-
Angiogenic growth factors in neural embryogenesis and neoplasia
-
Zagzag D. Angiogenic growth factors in neural embryogenesis and neoplasia. Am J Pathol 146 (1995) 293-309
-
(1995)
Am J Pathol
, vol.146
, pp. 293-309
-
-
Zagzag, D.1
-
32
-
-
0015291143
-
Tumor angiogenesis: a quantitative method for histologic grading
-
Brem S., Cotran R., and Folkman J. Tumor angiogenesis: a quantitative method for histologic grading. J Natl Cancer Inst 48 (1972) 347-356
-
(1972)
J Natl Cancer Inst
, vol.48
, pp. 347-356
-
-
Brem, S.1
Cotran, R.2
Folkman, J.3
-
34
-
-
0033674528
-
Expression of vascular permeability factor in glioblastoma specimens: correlation with tumor vascular endothelial surface and peritumoral edema
-
Vaquero J., Zurita M., Morales C., et al. Expression of vascular permeability factor in glioblastoma specimens: correlation with tumor vascular endothelial surface and peritumoral edema. J Neurooncol 49 (2000) 49-55
-
(2000)
J Neurooncol
, vol.49
, pp. 49-55
-
-
Vaquero, J.1
Zurita, M.2
Morales, C.3
-
35
-
-
0023891936
-
Neovascularization and tumor growth in the rabbit brain. A model for experimental studies of angiogenesis and the blood-brain barrier
-
Zagzag D., Brem S., and Robert F. Neovascularization and tumor growth in the rabbit brain. A model for experimental studies of angiogenesis and the blood-brain barrier. Am J Pathol 131 (1988) 361-372
-
(1988)
Am J Pathol
, vol.131
, pp. 361-372
-
-
Zagzag, D.1
Brem, S.2
Robert, F.3
-
36
-
-
0024413619
-
Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model
-
Zagzag D., Goldenberg M., and Brem S. Angiogenesis and blood-brain barrier breakdown modulate CT contrast enhancement: an experimental study in a rabbit brain-tumor model. AJR Am J Roentgenol 153 (1989) 141-146
-
(1989)
AJR Am J Roentgenol
, vol.153
, pp. 141-146
-
-
Zagzag, D.1
Goldenberg, M.2
Brem, S.3
-
37
-
-
0030665066
-
Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189
-
Cheng S.Y., Nagane M., Huang H.S., et al. Intracerebral tumor-associated hemorrhage caused by overexpression of the vascular endothelial growth factor isoforms VEGF121 and VEGF165 but not VEGF189. Proc Natl Acad Sci USA 94 (1997) 12081-12087
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 12081-12087
-
-
Cheng, S.Y.1
Nagane, M.2
Huang, H.S.3
-
38
-
-
0023233760
-
The relationship between the capillary structure and hemorrhage in gliomas
-
Liwnicz B.H., Wu S.Z., and Tew Jr. J.M. The relationship between the capillary structure and hemorrhage in gliomas. J Neurosurg 66 (1987) 536-541
-
(1987)
J Neurosurg
, vol.66
, pp. 536-541
-
-
Liwnicz, B.H.1
Wu, S.Z.2
Tew Jr., J.M.3
-
39
-
-
0037407302
-
Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology
-
Cha S., Johnson G., Wadghiri Y.Z., et al. Dynamic, contrast-enhanced perfusion MRI in mouse gliomas: correlation with histopathology. Magn Reson Med 49 (2003) 848-855
-
(2003)
Magn Reson Med
, vol.49
, pp. 848-855
-
-
Cha, S.1
Johnson, G.2
Wadghiri, Y.Z.3
-
40
-
-
0023831370
-
Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy
-
Earnest F.t., Kelly P.J., Scheithauer B.W., et al. Cerebral astrocytomas: histopathologic correlation of MR and CT contrast enhancement with stereotactic biopsy. Radiology 166 (1988) 823-827
-
(1988)
Radiology
, vol.166
, pp. 823-827
-
-
Earnest, F.t.1
Kelly, P.J.2
Scheithauer, B.W.3
-
41
-
-
0032916008
-
MRI enhancement and microvascular density in gliomas. Correlation with tumor cell proliferation
-
Tynninen O., Aronen H.J., Ruhala M., et al. MRI enhancement and microvascular density in gliomas. Correlation with tumor cell proliferation. Invest Radiol 34 (1999) 427-434
-
(1999)
Invest Radiol
, vol.34
, pp. 427-434
-
-
Tynninen, O.1
Aronen, H.J.2
Ruhala, M.3
-
42
-
-
0031941942
-
Vascular endothelial growth factor expression and vascular density as prognostic markers of survival in patients with low-grade astrocytoma
-
Abdulrauf S.I., Edvardsen K., Ho K.L., et al. Vascular endothelial growth factor expression and vascular density as prognostic markers of survival in patients with low-grade astrocytoma. J Neurosurg 88 (1998) 513-520
-
(1998)
J Neurosurg
, vol.88
, pp. 513-520
-
-
Abdulrauf, S.I.1
Edvardsen, K.2
Ho, K.L.3
-
43
-
-
0021803702
-
Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications
-
Burger P.C., Vogel F.S., Green S.B., et al. Glioblastoma multiforme and anaplastic astrocytoma. Pathologic criteria and prognostic implications. Cancer 56 (1985) 1106-1111
-
(1985)
Cancer
, vol.56
, pp. 1106-1111
-
-
Burger, P.C.1
Vogel, F.S.2
Green, S.B.3
-
44
-
-
0023700236
-
Grading of astrocytomas. A simple and reproducible method
-
Daumas-Duport C., Scheithauer B., O'Fallon J., et al. Grading of astrocytomas. A simple and reproducible method. Cancer 62 (1988) 2152-2165
-
(1988)
Cancer
, vol.62
, pp. 2152-2165
-
-
Daumas-Duport, C.1
Scheithauer, B.2
O'Fallon, J.3
-
45
-
-
0001843063
-
Glioblastoma
-
Kleihues P., and Cavenee W.K. (Eds), IARC Press, Lyon
-
Kleihues P., Burger P.C., Collins V.P., et al. Glioblastoma. In: Kleihues P., and Cavenee W.K. (Eds). Pathology and Genetics of Tumours of the Nervous System (2000), IARC Press, Lyon 29-39
-
(2000)
Pathology and Genetics of Tumours of the Nervous System
, pp. 29-39
-
-
Kleihues, P.1
Burger, P.C.2
Collins, V.P.3
-
46
-
-
0036896003
-
Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers
-
Straume O., Chappuis P.O., Salvesen H.B., et al. Prognostic importance of glomeruloid microvascular proliferation indicates an aggressive angiogenic phenotype in human cancers. Cancer Res 62 (2002) 6808-6811
-
(2002)
Cancer Res
, vol.62
, pp. 6808-6811
-
-
Straume, O.1
Chappuis, P.O.2
Salvesen, H.B.3
-
47
-
-
0016914733
-
The role of vascular proliferation in the growth of brain tumors
-
Brem S. The role of vascular proliferation in the growth of brain tumors. Clin Neurosurg 23 (1976) 440-453
-
(1976)
Clin Neurosurg
, vol.23
, pp. 440-453
-
-
Brem, S.1
-
48
-
-
0027201773
-
Induction of vascular endothelial tubular morphogenesis by human glioma cells. A model system for tumor angiogenesis
-
Abe T., Okamura K., Ono M., et al. Induction of vascular endothelial tubular morphogenesis by human glioma cells. A model system for tumor angiogenesis. J Clin Invest 92 (1993) 54-61
-
(1993)
J Clin Invest
, vol.92
, pp. 54-61
-
-
Abe, T.1
Okamura, K.2
Ono, M.3
-
49
-
-
0016708603
-
In vitro demonstration of an endothelial proliferative factor produced by neural cell lines
-
Suddith R.L., Kelly P.J., Hutchison H.T., et al. In vitro demonstration of an endothelial proliferative factor produced by neural cell lines. Science 190 (1975) 682-684
-
(1975)
Science
, vol.190
, pp. 682-684
-
-
Suddith, R.L.1
Kelly, P.J.2
Hutchison, H.T.3
-
50
-
-
27944442568
-
Angiogenesis: update 2005
-
Dvorak H.F. Angiogenesis: update 2005. J Thromb Haemost 3 (2005) 1835-1842
-
(2005)
J Thromb Haemost
, vol.3
, pp. 1835-1842
-
-
Dvorak, H.F.1
-
51
-
-
4143136640
-
Vascular endothelial growth factor: basic science and clinical progress
-
Ferrara N. Vascular endothelial growth factor: basic science and clinical progress. Endocr Rev 25 (2004) 581-611
-
(2004)
Endocr Rev
, vol.25
, pp. 581-611
-
-
Ferrara, N.1
-
52
-
-
0026446102
-
Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo
-
Plate K.H., Breier G., Weich H.A., et al. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature 359 (1992) 845-848
-
(1992)
Nature
, vol.359
, pp. 845-848
-
-
Plate, K.H.1
Breier, G.2
Weich, H.A.3
-
53
-
-
0031045279
-
Neovasculature induced by vascular endothelial growth factor is fenestrated
-
Roberts W.G., and Palade G.E. Neovasculature induced by vascular endothelial growth factor is fenestrated. Cancer Res 57 (1997) 765-772
-
(1997)
Cancer Res
, vol.57
, pp. 765-772
-
-
Roberts, W.G.1
Palade, G.E.2
-
54
-
-
0026485002
-
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
-
Shweiki D., Itin A., Soffer D., et al. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359 (1992) 843-845
-
(1992)
Nature
, vol.359
, pp. 843-845
-
-
Shweiki, D.1
Itin, A.2
Soffer, D.3
-
55
-
-
0142166332
-
Targeting HIF-1 for cancer therapy
-
Semenza G.L. Targeting HIF-1 for cancer therapy. Nat Rev Cancer 3 (2003) 721-732
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 721-732
-
-
Semenza, G.L.1
-
56
-
-
0034213146
-
Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression
-
Zagzag D., Zhong H., Scalzitti J.M., et al. Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression. Cancer 88 (2000) 2606-2618
-
(2000)
Cancer
, vol.88
, pp. 2606-2618
-
-
Zagzag, D.1
Zhong, H.2
Scalzitti, J.M.3
-
57
-
-
0017370183
-
Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis
-
Ausprunk D.H., and Folkman J. Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Research 14 (1977) 53-65
-
(1977)
Microvasc Research
, vol.14
, pp. 53-65
-
-
Ausprunk, D.H.1
Folkman, J.2
-
58
-
-
0032850844
-
The extracellular matrix of gliomas: modulation of cell function
-
Gladson C.L. The extracellular matrix of gliomas: modulation of cell function. J Neuropathol Exp Neurol 58 (1999) 1029-1040
-
(1999)
J Neuropathol Exp Neurol
, vol.58
, pp. 1029-1040
-
-
Gladson, C.L.1
-
59
-
-
27944465846
-
Changes in laminin isoforms associated with brain tumor invasion and angiogenesis
-
Ljubimova J.Y., Fujita M., Khazenzon N.M., et al. Changes in laminin isoforms associated with brain tumor invasion and angiogenesis. Front Biosci 11 (2006) 81-88
-
(2006)
Front Biosci
, vol.11
, pp. 81-88
-
-
Ljubimova, J.Y.1
Fujita, M.2
Khazenzon, N.M.3
-
60
-
-
0029097797
-
Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis
-
Mikkelsen T., Yan P.S., Ho K.L., et al. Immunolocalization of cathepsin B in human glioma: implications for tumor invasion and angiogenesis. J Neurosurg 83 (1995) 285-290
-
(1995)
J Neurosurg
, vol.83
, pp. 285-290
-
-
Mikkelsen, T.1
Yan, P.S.2
Ho, K.L.3
-
61
-
-
0030070486
-
Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro
-
Zagzag D., Friedlander D.R., Dosik J., et al. Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro. Cancer Res 56 (1996) 182-189
-
(1996)
Cancer Res
, vol.56
, pp. 182-189
-
-
Zagzag, D.1
Friedlander, D.R.2
Dosik, J.3
-
62
-
-
0028888390
-
Tenascin expression in astrocytomas correlates with angiogenesis
-
Zagzag D., Friedlander D.R., Miller D.C., et al. Tenascin expression in astrocytomas correlates with angiogenesis. Cancer Res 55 (1995) 907-914
-
(1995)
Cancer Res
, vol.55
, pp. 907-914
-
-
Zagzag, D.1
Friedlander, D.R.2
Miller, D.C.3
-
63
-
-
0037501115
-
Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells
-
Haskell H., Natarajan M., Hecker T.P., et al. Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular endothelial cells. Clin Cancer Res 9 (2003) 2157-2165
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2157-2165
-
-
Haskell, H.1
Natarajan, M.2
Hecker, T.P.3
-
64
-
-
0033766009
-
Molecular events implicated in brain tumor angiogenesis and invasion
-
Zagzag D., Friedlander D.R., Margolis B., et al. Molecular events implicated in brain tumor angiogenesis and invasion. Pediatr Neurosurg 33 (2000) 49-55
-
(2000)
Pediatr Neurosurg
, vol.33
, pp. 49-55
-
-
Zagzag, D.1
Friedlander, D.R.2
Margolis, B.3
-
65
-
-
0036570318
-
Tenascin-C promotes microvascular cell migration and phosphorylation of focal adhesion kinase
-
Zagzag D., Shiff B., Jallo G.I., et al. Tenascin-C promotes microvascular cell migration and phosphorylation of focal adhesion kinase. Cancer Res 62 (2002) 2660-2668
-
(2002)
Cancer Res
, vol.62
, pp. 2660-2668
-
-
Zagzag, D.1
Shiff, B.2
Jallo, G.I.3
-
66
-
-
0020331685
-
Angiogenesis: initiation and control
-
Folkman J. Angiogenesis: initiation and control. Ann N Y Acad Sci 401 (1982) 212-227
-
(1982)
Ann N Y Acad Sci
, vol.401
, pp. 212-227
-
-
Folkman, J.1
-
67
-
-
0021978223
-
Tumor angiogenesis
-
Folkman J. Tumor angiogenesis. Adv Cancer Res 43 (1985) 175-203
-
(1985)
Adv Cancer Res
, vol.43
, pp. 175-203
-
-
Folkman, J.1
-
68
-
-
0022648938
-
How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture
-
Folkman J. How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes Memorial Award Lecture. Cancer Res 46 (1986) 467-473
-
(1986)
Cancer Res
, vol.46
, pp. 467-473
-
-
Folkman, J.1
-
69
-
-
0033580889
-
Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF
-
Holash J., Maisonpierre P.C., Compton D., et al. Vessel cooption, regression, and growth in tumors mediated by angiopoietins and VEGF. Science 284 (1999) 1994-1998
-
(1999)
Science
, vol.284
, pp. 1994-1998
-
-
Holash, J.1
Maisonpierre, P.C.2
Compton, D.3
-
70
-
-
0033917495
-
Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis
-
Zagzag D., Amirnovin R., Greco M.A., et al. Vascular apoptosis and involution in gliomas precede neovascularization: a novel concept for glioma growth and angiogenesis. Lab Invest 80 (2000) 837-849
-
(2000)
Lab Invest
, vol.80
, pp. 837-849
-
-
Zagzag, D.1
Amirnovin, R.2
Greco, M.A.3
-
71
-
-
0032843659
-
In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis
-
Zagzag D., Hooper A., Friedlander D.R., et al. In situ expression of angiopoietins in astrocytomas identifies angiopoietin-2 as an early marker of tumor angiogenesis. Exp Neurol 159 (1999) 391-400
-
(1999)
Exp Neurol
, vol.159
, pp. 391-400
-
-
Zagzag, D.1
Hooper, A.2
Friedlander, D.R.3
-
72
-
-
2342436921
-
Anti-angiogenic chemotherapy in central nervous system tumors
-
Kieran M.W. Anti-angiogenic chemotherapy in central nervous system tumors. Cancer Treat Res 117 (2004) 337-349
-
(2004)
Cancer Treat Res
, vol.117
, pp. 337-349
-
-
Kieran, M.W.1
-
73
-
-
0032907687
-
Vascular endothelial growth factor (VEGF) and its receptors
-
Neufeld G., Cohen T., Gengrinovitch S., et al. Vascular endothelial growth factor (VEGF) and its receptors. FASEB J 13 (1999) 9-22
-
(1999)
FASEB J
, vol.13
, pp. 9-22
-
-
Neufeld, G.1
Cohen, T.2
Gengrinovitch, S.3
-
74
-
-
0141721621
-
Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders
-
Autiero M., Luttun A., Tjwa M., et al. Placental growth factor and its receptor, vascular endothelial growth factor receptor-1: novel targets for stimulation of ischemic tissue revascularization and inhibition of angiogenic and inflammatory disorders. J Thromb Haemost 1 (2003) 1356-1370
-
(2003)
J Thromb Haemost
, vol.1
, pp. 1356-1370
-
-
Autiero, M.1
Luttun, A.2
Tjwa, M.3
-
75
-
-
0037703184
-
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1
-
Autiero M., Waltenberger J., Communi D., et al. Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1. Nat Med 9 (2003) 936-943
-
(2003)
Nat Med
, vol.9
, pp. 936-943
-
-
Autiero, M.1
Waltenberger, J.2
Communi, D.3
-
76
-
-
14644440555
-
Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
-
Hicklin D.J., and Ellis L.M. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol 23 (2005) 1011-1027
-
(2005)
J Clin Oncol
, vol.23
, pp. 1011-1027
-
-
Hicklin, D.J.1
Ellis, L.M.2
-
77
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2 (2002) 795-803
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 795-803
-
-
Ferrara, N.1
-
78
-
-
0037699954
-
The biology of VEGF and its receptors
-
Ferrara N., Gerber H.P., and LeCouter J. The biology of VEGF and its receptors. Nat Med 9 (2003) 669-676
-
(2003)
Nat Med
, vol.9
, pp. 669-676
-
-
Ferrara, N.1
Gerber, H.P.2
LeCouter, J.3
-
79
-
-
0037182861
-
VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism
-
Gerber H.P., Malik A.K., Solar G.P., et al. VEGF regulates haematopoietic stem cell survival by an internal autocrine loop mechanism. Nature 417 (2002) 954-958
-
(2002)
Nature
, vol.417
, pp. 954-958
-
-
Gerber, H.P.1
Malik, A.K.2
Solar, G.P.3
-
80
-
-
0036344496
-
Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment
-
Hattori K., Heissig B., Wu Y., et al. Placental growth factor reconstitutes hematopoiesis by recruiting VEGFR1(+) stem cells from bone-marrow microenvironment. Nat Med 8 (2002) 841-849
-
(2002)
Nat Med
, vol.8
, pp. 841-849
-
-
Hattori, K.1
Heissig, B.2
Wu, Y.3
-
81
-
-
0036344495
-
Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1
-
Luttun A., Tjwa M., Moons L., et al. Revascularization of ischemic tissues by PlGF treatment, and inhibition of tumor angiogenesis, arthritis and atherosclerosis by anti-Flt1. Nat Med 8 (2002) 831-840
-
(2002)
Nat Med
, vol.8
, pp. 831-840
-
-
Luttun, A.1
Tjwa, M.2
Moons, L.3
-
82
-
-
0036782035
-
MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis
-
Hiratsuka S., Nakamura K., Iwai S., et al. MMP9 induction by vascular endothelial growth factor receptor-1 is involved in lung-specific metastasis. Cancer Cell 2 (2002) 289-300
-
(2002)
Cancer Cell
, vol.2
, pp. 289-300
-
-
Hiratsuka, S.1
Nakamura, K.2
Iwai, S.3
-
83
-
-
0037423321
-
Angiogenesis-independent endothelial protection of liver: role of VEGFR-1
-
LeCouter J., Moritz D.R., Li B., et al. Angiogenesis-independent endothelial protection of liver: role of VEGFR-1. Science 299 (2003) 890-893
-
(2003)
Science
, vol.299
, pp. 890-893
-
-
LeCouter, J.1
Moritz, D.R.2
Li, B.3
-
84
-
-
0037362890
-
HIF hydroxylation and the mammalian oxygen-sensing pathway
-
Safran M., and Kaelin Jr. W.G. HIF hydroxylation and the mammalian oxygen-sensing pathway. J Clin Invest 111 (2003) 779-783
-
(2003)
J Clin Invest
, vol.111
, pp. 779-783
-
-
Safran, M.1
Kaelin Jr., W.G.2
-
85
-
-
17844396959
-
Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1
-
Loeffler S., Fayard B., Weis J., et al. Interleukin-6 induces transcriptional activation of vascular endothelial growth factor (VEGF) in astrocytes in vivo and regulates VEGF promoter activity in glioblastoma cells via direct interaction between STAT3 and Sp1. Int J Cancer 115 (2005) 202-213
-
(2005)
Int J Cancer
, vol.115
, pp. 202-213
-
-
Loeffler, S.1
Fayard, B.2
Weis, J.3
-
86
-
-
0344578062
-
Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis
-
Valter M.M., Hugel A., Huang H.J., et al. Expression of the Ets-1 transcription factor in human astrocytomas is associated with Fms-like tyrosine kinase-1 (Flt-1)/vascular endothelial growth factor receptor-1 synthesis and neoangiogenesis. Cancer Res 59 (1999) 5608-5614
-
(1999)
Cancer Res
, vol.59
, pp. 5608-5614
-
-
Valter, M.M.1
Hugel, A.2
Huang, H.J.3
-
87
-
-
22844451172
-
Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression
-
Sahin A., Velten M., Pietsch T., et al. Inactivation of Ets 1 transcription factor by a specific decoy strategy reduces rat C6 glioma cell proliferation and mmp-9 expression. Int J Mol Med 15 (2005) 771-776
-
(2005)
Int J Mol Med
, vol.15
, pp. 771-776
-
-
Sahin, A.1
Velten, M.2
Pietsch, T.3
-
88
-
-
0030046481
-
Interleukin 6 induces the expression of vascular endothelial growth factor
-
Cohen T., Nahari D., Cerem L.W., et al. Interleukin 6 induces the expression of vascular endothelial growth factor. J Biol Chem 271 (1996) 736-741
-
(1996)
J Biol Chem
, vol.271
, pp. 736-741
-
-
Cohen, T.1
Nahari, D.2
Cerem, L.W.3
-
89
-
-
0026673043
-
Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C
-
Finkenzeller G., Marme D., Weich H.A., et al. Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C. Cancer Res 52 (1992) 4821-4823
-
(1992)
Cancer Res
, vol.52
, pp. 4821-4823
-
-
Finkenzeller, G.1
Marme, D.2
Weich, H.A.3
-
90
-
-
0344837389
-
Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
-
Guo P., Hu B., Gu W., et al. Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am J Pathol 162 (2003) 1083-1093
-
(2003)
Am J Pathol
, vol.162
, pp. 1083-1093
-
-
Guo, P.1
Hu, B.2
Gu, W.3
-
91
-
-
0028221238
-
Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells
-
Pertovaara L., Kaipainen A., Mustonen T., et al. Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. J Biol Chem 269 (1994) 6271-6274
-
(1994)
J Biol Chem
, vol.269
, pp. 6271-6274
-
-
Pertovaara, L.1
Kaipainen, A.2
Mustonen, T.3
-
92
-
-
0028941001
-
Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF
-
Tsai J.C., Goldman C.K., and Gillespie G.Y. Vascular endothelial growth factor in human glioma cell lines: induced secretion by EGF, PDGF-BB, and bFGF. J Neurosurg 82 (1995) 864-873
-
(1995)
J Neurosurg
, vol.82
, pp. 864-873
-
-
Tsai, J.C.1
Goldman, C.K.2
Gillespie, G.Y.3
-
93
-
-
0033119572
-
Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase
-
Wang D., Huang H.J., Kazlauskas A., et al. Induction of vascular endothelial growth factor expression in endothelial cells by platelet-derived growth factor through the activation of phosphatidylinositol 3-kinase. Cancer Res 59 (1999) 1464-1472
-
(1999)
Cancer Res
, vol.59
, pp. 1464-1472
-
-
Wang, D.1
Huang, H.J.2
Kazlauskas, A.3
-
94
-
-
0036842215
-
Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy
-
Dvorak H.F. Vascular permeability factor/vascular endothelial growth factor: a critical cytokine in tumor angiogenesis and a potential target for diagnosis and therapy. J Clin Oncol 20 (2002) 4368-4380
-
(2002)
J Clin Oncol
, vol.20
, pp. 4368-4380
-
-
Dvorak, H.F.1
-
95
-
-
0027534287
-
Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms
-
Berkman R.A., Merrill M.J., Reinhold W.C., et al. Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms. J Clin Invest 91 (1993) 153-159
-
(1993)
J Clin Invest
, vol.91
, pp. 153-159
-
-
Berkman, R.A.1
Merrill, M.J.2
Reinhold, W.C.3
-
96
-
-
0036780251
-
Clinical translation of angiogenesis inhibitors
-
Kerbel R., and Folkman J. Clinical translation of angiogenesis inhibitors. Nat Rev Cancer 2 (2002) 727-739
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 727-739
-
-
Kerbel, R.1
Folkman, J.2
-
97
-
-
0028822834
-
Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis
-
Rak J., Mitsuhashi Y., Bayko L., et al. Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis. Cancer Res 55 (1995) 4575-4580
-
(1995)
Cancer Res
, vol.55
, pp. 4575-4580
-
-
Rak, J.1
Mitsuhashi, Y.2
Bayko, L.3
-
98
-
-
0034668187
-
Signaling angiogenesis via p42/p44 MAP kinase and hypoxia
-
Berra E., Milanini J., Richard D.E., et al. Signaling angiogenesis via p42/p44 MAP kinase and hypoxia. Biochem Pharmacol 60 (2000) 1171-1178
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1171-1178
-
-
Berra, E.1
Milanini, J.2
Richard, D.E.3
-
99
-
-
0029785838
-
Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene
-
Gnarra J.R., Zhou S., Merrill M.J., et al. Post-transcriptional regulation of vascular endothelial growth factor mRNA by the product of the VHL tumor suppressor gene. Proc Natl Acad Sci USA 93 (1996) 10589-10594
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 10589-10594
-
-
Gnarra, J.R.1
Zhou, S.2
Merrill, M.J.3
-
100
-
-
0038507194
-
Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas
-
Na X., Wu G., Ryan C.K., et al. Overproduction of vascular endothelial growth factor related to von Hippel-Lindau tumor suppressor gene mutations and hypoxia-inducible factor-1 alpha expression in renal cell carcinomas. J Urol 170 (2003) 588-592
-
(2003)
J Urol
, vol.170
, pp. 588-592
-
-
Na, X.1
Wu, G.2
Ryan, C.K.3
-
101
-
-
0037228960
-
PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter
-
Pore N., Liu S., Haas-Kogan D.A., et al. PTEN mutation and epidermal growth factor receptor activation regulate vascular endothelial growth factor (VEGF) mRNA expression in human glioblastoma cells by transactivating the proximal VEGF promoter. Cancer Res 63 (2003) 236-241
-
(2003)
Cancer Res
, vol.63
, pp. 236-241
-
-
Pore, N.1
Liu, S.2
Haas-Kogan, D.A.3
-
103
-
-
0033573895
-
VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases
-
Doanes A.M., Hegland D.D., Sethi R., et al. VEGF stimulates MAPK through a pathway that is unique for receptor tyrosine kinases. Biochem Biophys Res Commun 255 (1999) 545-548
-
(1999)
Biochem Biophys Res Commun
, vol.255
, pp. 545-548
-
-
Doanes, A.M.1
Hegland, D.D.2
Sethi, R.3
-
104
-
-
0034979273
-
Role of vascular endothelial growth factor in regulation of physiological angiogenesis
-
Ferrara N. Role of vascular endothelial growth factor in regulation of physiological angiogenesis. Am J Physiol Cell Physiol 280 (2001) C1358-C1366
-
(2001)
Am J Physiol Cell Physiol
, vol.280
-
-
Ferrara, N.1
-
105
-
-
0031825437
-
Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells
-
Esser S., Lampugnani M.G., Corada M., et al. Vascular endothelial growth factor induces VE-cadherin tyrosine phosphorylation in endothelial cells. J Cell Sci 111 (1998) 1853-1865
-
(1998)
J Cell Sci
, vol.111
, pp. 1853-1865
-
-
Esser, S.1
Lampugnani, M.G.2
Corada, M.3
-
106
-
-
2642607848
-
Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins
-
Kevil C.G., Payne D.K., Mire E., et al. Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins. J Biol Chem 273 (1998) 15099-15103
-
(1998)
J Biol Chem
, vol.273
, pp. 15099-15103
-
-
Kevil, C.G.1
Payne, D.K.2
Mire, E.3
-
107
-
-
0034754014
-
VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways
-
Lal B.K., Varma S., Pappas P.J., et al. VEGF increases permeability of the endothelial cell monolayer by activation of PKB/akt, endothelial nitric-oxide synthase, and MAP kinase pathways. Microvasc Res 62 (2001) 252-262
-
(2001)
Microvasc Res
, vol.62
, pp. 252-262
-
-
Lal, B.K.1
Varma, S.2
Pappas, P.J.3
-
108
-
-
0028968307
-
Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells
-
Mandriota S.J., Seghezzi G., Vassalli J.D., et al. Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells. J Biol Chem 270 (1995) 9709-9716
-
(1995)
J Biol Chem
, vol.270
, pp. 9709-9716
-
-
Mandriota, S.J.1
Seghezzi, G.2
Vassalli, J.D.3
-
109
-
-
0026321129
-
Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells
-
Pepper M.S., Ferrara N., Orci L., et al. Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 181 (1991) 902-906
-
(1991)
Biochem Biophys Res Commun
, vol.181
, pp. 902-906
-
-
Pepper, M.S.1
Ferrara, N.2
Orci, L.3
-
110
-
-
0032540943
-
The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells
-
Tang H., Kerins D.M., Hao Q., et al. The urokinase-type plasminogen activator receptor mediates tyrosine phosphorylation of focal adhesion proteins and activation of mitogen-activated protein kinase in cultured endothelial cells. J Biol Chem 273 (1998) 18268-18272
-
(1998)
J Biol Chem
, vol.273
, pp. 18268-18272
-
-
Tang, H.1
Kerins, D.M.2
Hao, Q.3
-
111
-
-
0031459892
-
Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins
-
Senger D.R., Claffey K.P., Benes J.E., et al. Angiogenesis promoted by vascular endothelial growth factor: regulation through alpha1beta1 and alpha2beta1 integrins. Proc Natl Acad Sci USA 94 (1997) 13612-13617
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 13612-13617
-
-
Senger, D.R.1
Claffey, K.P.2
Benes, J.E.3
-
112
-
-
0029999603
-
Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin
-
Senger D.R., Ledbetter S.R., Claffey K.P., et al. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 149 (1996) 293-305
-
(1996)
Am J Pathol
, vol.149
, pp. 293-305
-
-
Senger, D.R.1
Ledbetter, S.R.2
Claffey, K.P.3
-
113
-
-
0034076189
-
Mechanisms of angiogenesis and arteriogenesis
-
Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 6 (2000) 389-395
-
(2000)
Nat Med
, vol.6
, pp. 389-395
-
-
Carmeliet, P.1
-
114
-
-
0032557564
-
Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
-
Gerber H.P., Dixit V., and Ferrara N. Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells. J Biol Chem 273 (1998) 13313-13316
-
(1998)
J Biol Chem
, vol.273
, pp. 13313-13316
-
-
Gerber, H.P.1
Dixit, V.2
Ferrara, N.3
-
115
-
-
0032515047
-
Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
-
Gerber H.P., McMurtrey A., Kowalski J., et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3′-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem 273 (1998) 30336-30343
-
(1998)
J Biol Chem
, vol.273
, pp. 30336-30343
-
-
Gerber, H.P.1
McMurtrey, A.2
Kowalski, J.3
-
116
-
-
0030999445
-
Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells
-
Watanabe Y., Lee S.W., Detmar M., et al. Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) delays and induces escape from senescence in human dermal microvascular endothelial cells. Oncogene 14 (1997) 2025-2032
-
(1997)
Oncogene
, vol.14
, pp. 2025-2032
-
-
Watanabe, Y.1
Lee, S.W.2
Detmar, M.3
-
117
-
-
0031583917
-
Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase
-
Wheeler-Jones C., Abu-Ghazaleh R., Cospedal R., et al. Vascular endothelial growth factor stimulates prostacyclin production and activation of cytosolic phospholipase A2 in endothelial cells via p42/p44 mitogen-activated protein kinase. FEBS Lett 420 (1997) 28-32
-
(1997)
FEBS Lett
, vol.420
, pp. 28-32
-
-
Wheeler-Jones, C.1
Abu-Ghazaleh, R.2
Cospedal, R.3
-
118
-
-
0033558798
-
VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
-
Gupta K., Kshirsagar S., Li W., et al. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp Cell Res 247 (1999) 495-504
-
(1999)
Exp Cell Res
, vol.247
, pp. 495-504
-
-
Gupta, K.1
Kshirsagar, S.2
Li, W.3
-
119
-
-
0033965483
-
Akt takes center stage in angiogenesis signaling
-
Dimmeler S., and Zeiher A.M. Akt takes center stage in angiogenesis signaling. Circ Res 86 (2000) 4-5
-
(2000)
Circ Res
, vol.86
, pp. 4-5
-
-
Dimmeler, S.1
Zeiher, A.M.2
-
120
-
-
0034652392
-
Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells
-
Jiang B.H., Zheng J.Z., Aoki M., et al. Phosphatidylinositol 3-kinase signaling mediates angiogenesis and expression of vascular endothelial growth factor in endothelial cells. Proc Natl Acad Sci USA 97 (2000) 1749-1753
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 1749-1753
-
-
Jiang, B.H.1
Zheng, J.Z.2
Aoki, M.3
-
121
-
-
0033522927
-
Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner
-
Fujio Y., and Walsh K. Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner. J Biol Chem 274 (1999) 16349-16354
-
(1999)
J Biol Chem
, vol.274
, pp. 16349-16354
-
-
Fujio, Y.1
Walsh, K.2
-
122
-
-
0033517244
-
Akt is more than just a Bad kinase
-
Khwaja A. Akt is more than just a Bad kinase. Nature 401 (1999) 33-34
-
(1999)
Nature
, vol.401
, pp. 33-34
-
-
Khwaja, A.1
-
123
-
-
0034724736
-
Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt
-
Morales-Ruiz M., Fulton D., Sowa G., et al. Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ Res 86 (2000) 892-896
-
(2000)
Circ Res
, vol.86
, pp. 892-896
-
-
Morales-Ruiz, M.1
Fulton, D.2
Sowa, G.3
-
124
-
-
0030869787
-
Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
-
Mazure N.M., Chen E.Y., Laderoute K.R., et al. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood 90 (1997) 3322-3331
-
(1997)
Blood
, vol.90
, pp. 3322-3331
-
-
Mazure, N.M.1
Chen, E.Y.2
Laderoute, K.R.3
-
125
-
-
0033542476
-
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
-
Dimmeler S., Fleming I., Fisslthaler B., et al. Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation. Nature 399 (1999) 601-605
-
(1999)
Nature
, vol.399
, pp. 601-605
-
-
Dimmeler, S.1
Fleming, I.2
Fisslthaler, B.3
-
126
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
Fulton D., Gratton J.P., McCabe T.J., et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399 (1999) 597-601
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
Gratton, J.P.2
McCabe, T.J.3
-
127
-
-
0343851651
-
Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells
-
Dulak J., Jozkowicz A., Dembinska-Kiec A., et al. Nitric oxide induces the synthesis of vascular endothelial growth factor by rat vascular smooth muscle cells. Arterioscler Thromb Vasc Biol 20 (2000) 659-666
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 659-666
-
-
Dulak, J.1
Jozkowicz, A.2
Dembinska-Kiec, A.3
-
128
-
-
0030918007
-
Nitric oxide promotes proliferation and plasminogen activator production by coronary venular endothelium through endogenous bFGF
-
Ziche M., Parenti A., Ledda F., et al. Nitric oxide promotes proliferation and plasminogen activator production by coronary venular endothelium through endogenous bFGF. Circ Res 80 (1997) 845-852
-
(1997)
Circ Res
, vol.80
, pp. 845-852
-
-
Ziche, M.1
Parenti, A.2
Ledda, F.3
-
129
-
-
0034698284
-
Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration
-
Dimmeler S., Dernbach E., and Zeiher A.M. Phosphorylation of the endothelial nitric oxide synthase at ser-1177 is required for VEGF-induced endothelial cell migration. FEBS Lett 477 (2000) 258-262
-
(2000)
FEBS Lett
, vol.477
, pp. 258-262
-
-
Dimmeler, S.1
Dernbach, E.2
Zeiher, A.M.3
-
131
-
-
0028143547
-
Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P
-
Ziche M., Morbidelli L., Masini E., et al. Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J Clin Invest 94 (1994) 2036-2044
-
(1994)
J Clin Invest
, vol.94
, pp. 2036-2044
-
-
Ziche, M.1
Morbidelli, L.2
Masini, E.3
-
132
-
-
0031737425
-
Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis
-
Stratmann A., Risau W., and Plate K.H. Cell type-specific expression of angiopoietin-1 and angiopoietin-2 suggests a role in glioblastoma angiogenesis. Am J Pathol 153 (1998) 1459-1466
-
(1998)
Am J Pathol
, vol.153
, pp. 1459-1466
-
-
Stratmann, A.1
Risau, W.2
Plate, K.H.3
-
133
-
-
1542319875
-
Targeting the Tie2/Tek receptor in astrocytomas
-
Zadeh G., Qian B., Okhowat A., et al. Targeting the Tie2/Tek receptor in astrocytomas. Am J Pathol 164 (2004) 467-476
-
(2004)
Am J Pathol
, vol.164
, pp. 467-476
-
-
Zadeh, G.1
Qian, B.2
Okhowat, A.3
-
134
-
-
15144358851
-
Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
-
Maisonpierre P.C., Suri C., Jones P.F., et al. Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis. Science 277 (1997) 55-60
-
(1997)
Science
, vol.277
, pp. 55-60
-
-
Maisonpierre, P.C.1
Suri, C.2
Jones, P.F.3
-
135
-
-
0006677050
-
Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-Kinase/Akt signal transduction pathway
-
Kim I., Kim H.G., So J.N., et al. Angiopoietin-1 regulates endothelial cell survival through the phosphatidylinositol 3′-Kinase/Akt signal transduction pathway. Circ Res 86 (2000) 24-29
-
(2000)
Circ Res
, vol.86
, pp. 24-29
-
-
Kim, I.1
Kim, H.G.2
So, J.N.3
-
136
-
-
0036018747
-
Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells
-
Harfouche R., Hassessian H.M., Guo Y., et al. Mechanisms which mediate the antiapoptotic effects of angiopoietin-1 on endothelial cells. Microvasc Res 64 (2002) 135-147
-
(2002)
Microvasc Res
, vol.64
, pp. 135-147
-
-
Harfouche, R.1
Hassessian, H.M.2
Guo, Y.3
-
137
-
-
0034737422
-
Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway
-
Papapetropoulos A., Fulton D., Mahboubi K., et al. Angiopoietin-1 inhibits endothelial cell apoptosis via the Akt/survivin pathway. J Biol Chem 275 (2000) 9102-9105
-
(2000)
J Biol Chem
, vol.275
, pp. 9102-9105
-
-
Papapetropoulos, A.1
Fulton, D.2
Mahboubi, K.3
-
138
-
-
0342657703
-
Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion
-
Kim I., Kim H.G., Moon S.O., et al. Angiopoietin-1 induces endothelial cell sprouting through the activation of focal adhesion kinase and plasmin secretion. Circ Res 86 (2000) 952-959
-
(2000)
Circ Res
, vol.86
, pp. 952-959
-
-
Kim, I.1
Kim, H.G.2
Moon, S.O.3
-
139
-
-
0037143737
-
Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo
-
Lobov I.B., Brooks P.C., and Lang R.A. Angiopoietin-2 displays VEGF-dependent modulation of capillary structure and endothelial cell survival in vivo. Proc Natl Acad Sci USA 99 (2002) 11205-11210
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 11205-11210
-
-
Lobov, I.B.1
Brooks, P.C.2
Lang, R.A.3
-
140
-
-
0032941495
-
Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis
-
Schmidt N.O., Westphal M., Hagel C., et al. Levels of vascular endothelial growth factor, hepatocyte growth factor/scatter factor and basic fibroblast growth factor in human gliomas and their relation to angiogenesis. Int J Cancer 84 (1999) 10-18
-
(1999)
Int J Cancer
, vol.84
, pp. 10-18
-
-
Schmidt, N.O.1
Westphal, M.2
Hagel, C.3
-
141
-
-
0025201337
-
Immunohistochemical localization of basic fibroblast growth factor in astrocytomas
-
Zagzag D., Miller D.C., Sato Y., et al. Immunohistochemical localization of basic fibroblast growth factor in astrocytomas. Cancer Res 50 (1990) 7393-7398
-
(1990)
Cancer Res
, vol.50
, pp. 7393-7398
-
-
Zagzag, D.1
Miller, D.C.2
Sato, Y.3
-
142
-
-
0038724937
-
Role of Raf in vascular protection from distinct apoptotic stimuli
-
Alavi A., Hood J.D., Frausto R., et al. Role of Raf in vascular protection from distinct apoptotic stimuli. Science 301 (2003) 94-96
-
(2003)
Science
, vol.301
, pp. 94-96
-
-
Alavi, A.1
Hood, J.D.2
Frausto, R.3
-
143
-
-
0037023780
-
Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis
-
Pardo O.E., Arcaro A., Salerno G., et al. Fibroblast growth factor-2 induces translational regulation of Bcl-XL and Bcl-2 via a MEK-dependent pathway: correlation with resistance to etoposide-induced apoptosis. J Biol Chem 277 (2002) 12040-12046
-
(2002)
J Biol Chem
, vol.277
, pp. 12040-12046
-
-
Pardo, O.E.1
Arcaro, A.2
Salerno, G.3
-
144
-
-
18344363186
-
Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma
-
Yoshiji H., Kuriyama S., Yoshii J., et al. Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma. Hepatology 35 (2002) 834-842
-
(2002)
Hepatology
, vol.35
, pp. 834-842
-
-
Yoshiji, H.1
Kuriyama, S.2
Yoshii, J.3
-
145
-
-
0030848490
-
Vascular endothelial growth factor-induced in vitro angiogenesis and plasminogen activator expression are dependent on endogenous basic fibroblast growth factor
-
Mandriota S.J., and Pepper M.S. Vascular endothelial growth factor-induced in vitro angiogenesis and plasminogen activator expression are dependent on endogenous basic fibroblast growth factor. J Cell Sci 110 (1997) 2293-2302
-
(1997)
J Cell Sci
, vol.110
, pp. 2293-2302
-
-
Mandriota, S.J.1
Pepper, M.S.2
-
146
-
-
0017370183
-
Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis
-
Ausprunk D.H., and Folkman J. Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc Res 14 (1977) 53-65
-
(1977)
Microvasc Res
, vol.14
, pp. 53-65
-
-
Ausprunk, D.H.1
Folkman, J.2
-
147
-
-
0024077722
-
Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis
-
Sato Y., and Rifkin D.B. Autocrine activities of basic fibroblast growth factor: regulation of endothelial cell movement, plasminogen activator synthesis, and DNA synthesis. J Cell Biol 107 (1988) 1199-1205
-
(1988)
J Cell Biol
, vol.107
, pp. 1199-1205
-
-
Sato, Y.1
Rifkin, D.B.2
-
148
-
-
0030756325
-
Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
-
Lindahl P., Johansson B.R., Leveen P., et al. Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277 (1997) 242-245
-
(1997)
Science
, vol.277
, pp. 242-245
-
-
Lindahl, P.1
Johansson, B.R.2
Leveen, P.3
-
149
-
-
0038476608
-
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors
-
Bergers G., Song S., Meyer-Morse N., et al. Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors. J Clin Invest 111 (2003) 1287-1295
-
(2003)
J Clin Invest
, vol.111
, pp. 1287-1295
-
-
Bergers, G.1
Song, S.2
Meyer-Morse, N.3
-
150
-
-
22744445537
-
Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors
-
Sun J., Wang D.A., Jain R.K., et al. Inhibiting angiogenesis and tumorigenesis by a synthetic molecule that blocks binding of both VEGF and PDGF to their receptors. Oncogene 24 (2005) 4701-4709
-
(2005)
Oncogene
, vol.24
, pp. 4701-4709
-
-
Sun, J.1
Wang, D.A.2
Jain, R.K.3
-
151
-
-
0035347301
-
Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival
-
Reinmuth N., Liu W., Jung Y.D., et al. Induction of VEGF in perivascular cells defines a potential paracrine mechanism for endothelial cell survival. FASEB J 15 (2001) 1239-1241
-
(2001)
FASEB J
, vol.15
, pp. 1239-1241
-
-
Reinmuth, N.1
Liu, W.2
Jung, Y.D.3
-
152
-
-
0034467330
-
Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs
-
Dunn I.F., Heese O., and Black P.M. Growth factors in glioma angiogenesis: FGFs, PDGF, EGF, and TGFs. J Neurooncol 50 (2000) 121-137
-
(2000)
J Neurooncol
, vol.50
, pp. 121-137
-
-
Dunn, I.F.1
Heese, O.2
Black, P.M.3
-
153
-
-
0025803828
-
Expression of angiogenic growth factor genes in primary human astrocytomas may contribute to their growth and progression
-
Maxwell M., Naber S.P., Wolfe H.J., et al. Expression of angiogenic growth factor genes in primary human astrocytomas may contribute to their growth and progression. Cancer Res 51 (1991) 1345-1351
-
(1991)
Cancer Res
, vol.51
, pp. 1345-1351
-
-
Maxwell, M.1
Naber, S.P.2
Wolfe, H.J.3
-
154
-
-
0027412319
-
Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology
-
Goldman C.K., Kim J., Wong W.L., et al. Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: a model of glioblastoma multiforme pathophysiology. Mol Biol Cell 4 (1993) 121-133
-
(1993)
Mol Biol Cell
, vol.4
, pp. 121-133
-
-
Goldman, C.K.1
Kim, J.2
Wong, W.L.3
-
155
-
-
0033051030
-
Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras
-
Feldkamp M.M., Lau N., Rak J., et al. Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras. Int J Cancer 81 (1999) 118-124
-
(1999)
Int J Cancer
, vol.81
, pp. 118-124
-
-
Feldkamp, M.M.1
Lau, N.2
Rak, J.3
-
156
-
-
16644367311
-
IkappaBalphaM suppresses angiogenesis and tumorigenesis promoted by a constitutively active mutant EGFR in human glioma cells
-
Wu J.L., Abe T., Inoue R., et al. IkappaBalphaM suppresses angiogenesis and tumorigenesis promoted by a constitutively active mutant EGFR in human glioma cells. Neurol Res 26 (2004) 785-791
-
(2004)
Neurol Res
, vol.26
, pp. 785-791
-
-
Wu, J.L.1
Abe, T.2
Inoue, R.3
-
157
-
-
0029114319
-
Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma
-
Yamada N., Kato M., Yamashita H., et al. Enhanced expression of transforming growth factor-beta and its type-I and type-II receptors in human glioblastoma. Int J Cancer 62 (1995) 386-392
-
(1995)
Int J Cancer
, vol.62
, pp. 386-392
-
-
Yamada, N.1
Kato, M.2
Yamashita, H.3
-
158
-
-
45849110280
-
Transforming growth factor-beta (TGF-beta) and brain tumours
-
Luwor R.B., Kaye A.H., and Zhu H.J. Transforming growth factor-beta (TGF-beta) and brain tumours. J Clin Neurosci 15 (2008) 845-855
-
(2008)
J Clin Neurosci
, vol.15
, pp. 845-855
-
-
Luwor, R.B.1
Kaye, A.H.2
Zhu, H.J.3
-
159
-
-
0022515570
-
Transforming growth factor-beta inhibits endothelial cell proliferation
-
Frater-Schroder M., Muller G., Birchmeier W., et al. Transforming growth factor-beta inhibits endothelial cell proliferation. Biochem Biophys Res Commun 137 (1986) 295-302
-
(1986)
Biochem Biophys Res Commun
, vol.137
, pp. 295-302
-
-
Frater-Schroder, M.1
Muller, G.2
Birchmeier, W.3
-
160
-
-
0029883757
-
Transforming growth factor beta1 induces angiogenesis in vivo with a threshold pattern
-
Fajardo L.F., Prionas S.D., Kwan H.H., et al. Transforming growth factor beta1 induces angiogenesis in vivo with a threshold pattern. Lab Invest 74 (1996) 600-608
-
(1996)
Lab Invest
, vol.74
, pp. 600-608
-
-
Fajardo, L.F.1
Prionas, S.D.2
Kwan, H.H.3
-
161
-
-
0029871064
-
Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro
-
Koochekpour S., Merzak A., and Pilkington G.J. Vascular endothelial growth factor production is stimulated by gangliosides and TGF-beta isoforms in human glioma cells in vitro. Cancer Lett 102 (1996) 209-215
-
(1996)
Cancer Lett
, vol.102
, pp. 209-215
-
-
Koochekpour, S.1
Merzak, A.2
Pilkington, G.J.3
-
162
-
-
4444341835
-
SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility
-
Hjelmeland M.D., Hjelmeland A.B., Sathornsumetee S., et al. SB-431542, a small molecule transforming growth factor-beta-receptor antagonist, inhibits human glioma cell line proliferation and motility. Mol Cancer Ther 3 (2004) 737-745
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 737-745
-
-
Hjelmeland, M.D.1
Hjelmeland, A.B.2
Sathornsumetee, S.3
-
163
-
-
0035865158
-
Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape
-
Platten M., Wick W., and Weller M. Malignant glioma biology: role for TGF-beta in growth, motility, angiogenesis, and immune escape. Microsc Res Tech 52 (2001) 401-410
-
(2001)
Microsc Res Tech
, vol.52
, pp. 401-410
-
-
Platten, M.1
Wick, W.2
Weller, M.3
-
164
-
-
0034673243
-
Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V)beta(3) integrin expression
-
Platten M., Wick W., Wild-Bode C., et al. Transforming growth factors beta(1) (TGF-beta(1)) and TGF-beta(2) promote glioma cell migration via Up-regulation of alpha(V)beta(3) integrin expression. Biochem Biophys Res Commun 268 (2000) 607-611
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 607-611
-
-
Platten, M.1
Wick, W.2
Wild-Bode, C.3
-
165
-
-
85047681729
-
Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas
-
Kunkel P., Muller S., Schirmacher P., et al. Expression and localization of scatter factor/hepatocyte growth factor in human astrocytomas. Neuro Oncol 3 (2001) 82-88
-
(2001)
Neuro Oncol
, vol.3
, pp. 82-88
-
-
Kunkel, P.1
Muller, S.2
Schirmacher, P.3
-
166
-
-
0036365052
-
In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis
-
Abounader R., Lal B., Luddy C., et al. In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis. FASEB J 16 (2002) 108-110
-
(2002)
FASEB J
, vol.16
, pp. 108-110
-
-
Abounader, R.1
Lal, B.2
Luddy, C.3
-
167
-
-
0141925943
-
Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4
-
Brockmann M.A., Papadimitriou A., Brandt M., et al. Inhibition of intracerebral glioblastoma growth by local treatment with the scatter factor/hepatocyte growth factor-antagonist NK4. Clin Cancer Res 9 (2003) 4578-4585
-
(2003)
Clin Cancer Res
, vol.9
, pp. 4578-4585
-
-
Brockmann, M.A.1
Papadimitriou, A.2
Brandt, M.3
-
168
-
-
0026806805
-
Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system
-
Van Meir E., Ceska M., Effenberger F., et al. Interleukin-8 is produced in neoplastic and infectious diseases of the human central nervous system. Cancer Res 52 (1992) 4297-4305
-
(1992)
Cancer Res
, vol.52
, pp. 4297-4305
-
-
Van Meir, E.1
Ceska, M.2
Effenberger, F.3
-
169
-
-
0025027767
-
Human glioblastoma cells release interleukin 6 in vivo and in vitro
-
Van Meir E., Sawamura Y., Diserens A.C., et al. Human glioblastoma cells release interleukin 6 in vivo and in vitro. Cancer Res 50 (1990) 6683-6688
-
(1990)
Cancer Res
, vol.50
, pp. 6683-6688
-
-
Van Meir, E.1
Sawamura, Y.2
Diserens, A.C.3
-
170
-
-
17844397949
-
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis
-
Brat D.J., Bellail A.C., and Van Meir E.G. The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. Neuro Oncol 7 (2005) 122-133
-
(2005)
Neuro Oncol
, vol.7
, pp. 122-133
-
-
Brat, D.J.1
Bellail, A.C.2
Van Meir, E.G.3
-
171
-
-
0034872239
-
Interleukin-6 overexpression as a marker of malignancy in human gliomas
-
Rolhion C., Penault-Llorca F., Kemeny J.L., et al. Interleukin-6 overexpression as a marker of malignancy in human gliomas. J Neurosurg 94 (2001) 97-101
-
(2001)
J Neurosurg
, vol.94
, pp. 97-101
-
-
Rolhion, C.1
Penault-Llorca, F.2
Kemeny, J.L.3
-
172
-
-
0027404936
-
Interleukin-8 stimulates angiogenesis in rats
-
Hu D.E., Hori Y., and Fan T.P. Interleukin-8 stimulates angiogenesis in rats. Inflammation 17 (1993) 135-143
-
(1993)
Inflammation
, vol.17
, pp. 135-143
-
-
Hu, D.E.1
Hori, Y.2
Fan, T.P.3
-
173
-
-
0027097806
-
Interleukin-8 as a macrophage-derived mediator of angiogenesis
-
Koch A.E., Polverini P.J., Kunkel S.L., et al. Interleukin-8 as a macrophage-derived mediator of angiogenesis. Science 258 (1992) 1798-1801
-
(1992)
Science
, vol.258
, pp. 1798-1801
-
-
Koch, A.E.1
Polverini, P.J.2
Kunkel, S.L.3
-
174
-
-
0030856117
-
Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis
-
Desbaillets I., Diserens A.C., Tribolet N., et al. Upregulation of interleukin 8 by oxygen-deprived cells in glioblastoma suggests a role in leukocyte activation, chemotaxis, and angiogenesis. J Exp Med 186 (1997) 1201-1212
-
(1997)
J Exp Med
, vol.186
, pp. 1201-1212
-
-
Desbaillets, I.1
Diserens, A.C.2
Tribolet, N.3
-
175
-
-
0029417263
-
Dual pathways of tubular morphogenesis of vascular endothelial cells by human glioma cells: vascular endothelial growth factor/basic fibroblast growth factor and interleukin-8
-
Wakabayashi Y., Shono T., Isono M., et al. Dual pathways of tubular morphogenesis of vascular endothelial cells by human glioma cells: vascular endothelial growth factor/basic fibroblast growth factor and interleukin-8. Jpn J Cancer Res 86 (1995) 1189-1197
-
(1995)
Jpn J Cancer Res
, vol.86
, pp. 1189-1197
-
-
Wakabayashi, Y.1
Shono, T.2
Isono, M.3
-
176
-
-
0033580218
-
Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma
-
Desbaillets I., Diserens A.C., de Tribolet N., et al. Regulation of interleukin-8 expression by reduced oxygen pressure in human glioblastoma. Oncogene 18 (1999) 1447-1456
-
(1999)
Oncogene
, vol.18
, pp. 1447-1456
-
-
Desbaillets, I.1
Diserens, A.C.2
de Tribolet, N.3
-
177
-
-
0030789842
-
Distribution of endogenous tumour necrosis factor alpha in gliomas
-
Maruno M., Kovach J.S., Kelly P.J., et al. Distribution of endogenous tumour necrosis factor alpha in gliomas. J Clin Pathol 50 (1997) 559-562
-
(1997)
J Clin Pathol
, vol.50
, pp. 559-562
-
-
Maruno, M.1
Kovach, J.S.2
Kelly, P.J.3
-
178
-
-
0029155901
-
Detection of tumor necrosis factor-alpha protein and messenger RNA in human glial brain tumors: comparison of immunohistochemistry with in situ hybridization using molecular probes
-
Roessler K., Suchanek G., Breitschopf H., et al. Detection of tumor necrosis factor-alpha protein and messenger RNA in human glial brain tumors: comparison of immunohistochemistry with in situ hybridization using molecular probes. J Neurosurg 83 (1995) 291-297
-
(1995)
J Neurosurg
, vol.83
, pp. 291-297
-
-
Roessler, K.1
Suchanek, G.2
Breitschopf, H.3
-
179
-
-
0005636230
-
Effects of retinoic acid and tumor necrosis factor alpha on GL-15 glioblastoma cells
-
Chambaut-Guerin A.M., Costa S.L., Lefrancois T., et al. Effects of retinoic acid and tumor necrosis factor alpha on GL-15 glioblastoma cells. Neuroreport 11 (2000) 389-393
-
(2000)
Neuroreport
, vol.11
, pp. 389-393
-
-
Chambaut-Guerin, A.M.1
Costa, S.L.2
Lefrancois, T.3
-
180
-
-
0027732688
-
Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration
-
Slowik M.R., De Luca L.G., Fiers W., et al. Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration. Am J Pathol 143 (1993) 1724-1730
-
(1993)
Am J Pathol
, vol.143
, pp. 1724-1730
-
-
Slowik, M.R.1
De Luca, L.G.2
Fiers, W.3
-
181
-
-
0029953517
-
Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1
-
Ryuto M., Ono M., Izumi H., et al. Induction of vascular endothelial growth factor by tumor necrosis factor alpha in human glioma cells. Possible roles of SP-1. J Biol Chem 271 (1996) 28220-28228
-
(1996)
J Biol Chem
, vol.271
, pp. 28220-28228
-
-
Ryuto, M.1
Ono, M.2
Izumi, H.3
-
182
-
-
0031009807
-
Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis
-
Yoshida S., Ono M., Shono T., et al. Involvement of interleukin-8, vascular endothelial growth factor, and basic fibroblast growth factor in tumor necrosis factor alpha-dependent angiogenesis. Mol Cell Biol 17 (1997) 4015-4023
-
(1997)
Mol Cell Biol
, vol.17
, pp. 4015-4023
-
-
Yoshida, S.1
Ono, M.2
Shono, T.3
-
183
-
-
0032568608
-
CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth
-
Babic A.M., Kireeva M.L., Kolesnikova T.V., et al. CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth. Proc Natl Acad Sci USA 95 (1998) 6355-6360
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6355-6360
-
-
Babic, A.M.1
Kireeva, M.L.2
Kolesnikova, T.V.3
-
184
-
-
0032817965
-
Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo
-
Shimo T., Nakanishi T., Nishida T., et al. Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo. J Biochem 126 (1999) 137-145
-
(1999)
J Biochem
, vol.126
, pp. 137-145
-
-
Shimo, T.1
Nakanishi, T.2
Nishida, T.3
-
185
-
-
2242453283
-
Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells
-
Leu S.J., Lam S.C., and Lau L.F. Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells. J Biol Chem 277 (2002) 46248-46255
-
(2002)
J Biol Chem
, vol.277
, pp. 46248-46255
-
-
Leu, S.J.1
Lam, S.C.2
Lau, L.F.3
-
186
-
-
1642350329
-
Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas
-
Xie D., Yin D., Wang H.J., et al. Levels of expression of CYR61 and CTGF are prognostic for tumor progression and survival of individuals with gliomas. Clin Cancer Res 10 (2004) 2072-2081
-
(2004)
Clin Cancer Res
, vol.10
, pp. 2072-2081
-
-
Xie, D.1
Yin, D.2
Wang, H.J.3
-
187
-
-
0033108116
-
Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas
-
Hirano H., Lopes M.B., Laws Jr. E.R., et al. Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas. Neuro Oncol 1 (1999) 109-119
-
(1999)
Neuro Oncol
, vol.1
, pp. 109-119
-
-
Hirano, H.1
Lopes, M.B.2
Laws Jr., E.R.3
-
189
-
-
17844367105
-
Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery
-
discussion 390
-
Bello L., Francolini M., Marthyn P., et al. Alpha(v)beta3 and alpha(v)beta5 integrin expression in glioma periphery. Neurosurgery 49 (2001) 380-389 discussion 390
-
(2001)
Neurosurgery
, vol.49
, pp. 380-389
-
-
Bello, L.1
Francolini, M.2
Marthyn, P.3
-
190
-
-
35348866157
-
Integrins: molecular determinants of glioma invasion
-
D'Abaco G.M., and Kaye A.H. Integrins: molecular determinants of glioma invasion. J Clin Neurosci 14 (2007) 1041-1048
-
(2007)
J Clin Neurosci
, vol.14
, pp. 1041-1048
-
-
D'Abaco, G.M.1
Kaye, A.H.2
-
191
-
-
0033038483
-
Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas
-
Forsyth P.A., Wong H., Laing T.D., et al. Gelatinase-A (MMP-2), gelatinase-B (MMP-9) and membrane type matrix metalloproteinase-1 (MT1-MMP) are involved in different aspects of the pathophysiology of malignant gliomas. Br J Cancer 79 (1999) 1828-1835
-
(1999)
Br J Cancer
, vol.79
, pp. 1828-1835
-
-
Forsyth, P.A.1
Wong, H.2
Laing, T.D.3
-
192
-
-
0030030963
-
Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas
-
Rao J.S., Yamamoto M., Mohaman S., et al. Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas. Clin Exp Metastasis 14 (1996) 12-18
-
(1996)
Clin Exp Metastasis
, vol.14
, pp. 12-18
-
-
Rao, J.S.1
Yamamoto, M.2
Mohaman, S.3
-
193
-
-
0036207326
-
Proteases and the biology of glioma invasion
-
Binder D.K., and Berger M.S. Proteases and the biology of glioma invasion. J Neurooncol 56 (2002) 149-158
-
(2002)
J Neurooncol
, vol.56
, pp. 149-158
-
-
Binder, D.K.1
Berger, M.S.2
-
194
-
-
0031870786
-
Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro
-
Lamoreaux W.J., Fitzgerald M.E., Reiner A., et al. Vascular endothelial growth factor increases release of gelatinase A and decreases release of tissue inhibitor of metalloproteinases by microvascular endothelial cells in vitro. Microvasc Res 55 (1998) 29-42
-
(1998)
Microvasc Res
, vol.55
, pp. 29-42
-
-
Lamoreaux, W.J.1
Fitzgerald, M.E.2
Reiner, A.3
-
195
-
-
0034765067
-
Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta
-
Wick W., Platten M., and Weller M. Glioma cell invasion: regulation of metalloproteinase activity by TGF-beta. J Neurooncol 53 (2001) 177-185
-
(2001)
J Neurooncol
, vol.53
, pp. 177-185
-
-
Wick, W.1
Platten, M.2
Weller, M.3
-
196
-
-
0034650486
-
Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis
-
Yu Q., and Stamenkovic I. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. Genes Dev 14 (2000) 163-176
-
(2000)
Genes Dev
, vol.14
, pp. 163-176
-
-
Yu, Q.1
Stamenkovic, I.2
-
197
-
-
0031019745
-
Isolation of putative progenitor endothelial cells for angiogenesis
-
Asahara T., Murohara T., Sullivan A., et al. Isolation of putative progenitor endothelial cells for angiogenesis. Science 275 (1997) 964-967
-
(1997)
Science
, vol.275
, pp. 964-967
-
-
Asahara, T.1
Murohara, T.2
Sullivan, A.3
-
198
-
-
0032945433
-
Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization
-
Takahashi T., Kalka C., Masuda H., et al. Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularization. Nat Med 5 (1999) 434-438
-
(1999)
Nat Med
, vol.5
, pp. 434-438
-
-
Takahashi, T.1
Kalka, C.2
Masuda, H.3
-
199
-
-
18444389451
-
Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand
-
Heissig B., Hattori K., Dias S., et al. Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand. Cell 109 (2002) 625-637
-
(2002)
Cell
, vol.109
, pp. 625-637
-
-
Heissig, B.1
Hattori, K.2
Dias, S.3
-
200
-
-
0142195911
-
Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors
-
Ruzinova M.B., Schoer R.A., Gerald W., et al. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell 4 (2003) 277-289
-
(2003)
Cancer Cell
, vol.4
, pp. 277-289
-
-
Ruzinova, M.B.1
Schoer, R.A.2
Gerald, W.3
-
201
-
-
0038644403
-
Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells
-
De Palma M., Venneri M.A., Roca C., et al. Targeting exogenous genes to tumor angiogenesis by transplantation of genetically modified hematopoietic stem cells. Nat Med 9 (2003) 789-795
-
(2003)
Nat Med
, vol.9
, pp. 789-795
-
-
De Palma, M.1
Venneri, M.A.2
Roca, C.3
-
202
-
-
20144386931
-
Contribution of bone marrow-derived endothelial cells to human tumor vasculature
-
Peters B.A., Diaz L.A., Polyak K., et al. Contribution of bone marrow-derived endothelial cells to human tumor vasculature. Nat Med 11 (2005) 261-262
-
(2005)
Nat Med
, vol.11
, pp. 261-262
-
-
Peters, B.A.1
Diaz, L.A.2
Polyak, K.3
-
203
-
-
0034666258
-
Progress in antiangiogenic gene therapy of cancer
-
Feldman A.L., and Libutti S.K. Progress in antiangiogenic gene therapy of cancer. Cancer 89 (2000) 1181-1194
-
(2000)
Cancer
, vol.89
, pp. 1181-1194
-
-
Feldman, A.L.1
Libutti, S.K.2
-
204
-
-
0036105592
-
Production of matrix metalloproteinase-9 in early stage B-CLL: suppression by interferons
-
Bauvois B., Dumont J., Mathiot C., et al. Production of matrix metalloproteinase-9 in early stage B-CLL: suppression by interferons. Leukemia 16 (2002) 791-798
-
(2002)
Leukemia
, vol.16
, pp. 791-798
-
-
Bauvois, B.1
Dumont, J.2
Mathiot, C.3
-
205
-
-
0036554710
-
Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis
-
Izawa J.I., Sweeney P., Perrotte P., et al. Inhibition of tumorigenicity and metastasis of human bladder cancer growing in athymic mice by interferon-beta gene therapy results partially from various antiangiogenic effects including endothelial cell apoptosis. Clin Cancer Res 8 (2002) 1258-1270
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1258-1270
-
-
Izawa, J.I.1
Sweeney, P.2
Perrotte, P.3
-
206
-
-
0035043493
-
Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha
-
Ozawa S., Shinohara H., Kanayama H.O., et al. Suppression of angiogenesis and therapy of human colon cancer liver metastasis by systemic administration of interferon-alpha. Neoplasia 3 (2001) 154-164
-
(2001)
Neoplasia
, vol.3
, pp. 154-164
-
-
Ozawa, S.1
Shinohara, H.2
Kanayama, H.O.3
-
207
-
-
0032719528
-
Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule
-
Slaton J.W., Perrotte P., Inoue K., et al. Interferon-alpha-mediated down-regulation of angiogenesis-related genes and therapy of bladder cancer are dependent on optimization of biological dose and schedule. Clin Cancer Res 5 (1999) 2726-2734
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2726-2734
-
-
Slaton, J.W.1
Perrotte, P.2
Inoue, K.3
-
208
-
-
0036482917
-
Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: Report of 2 cases
-
Marler JJ, Rubin JB, Trede NS, et al. Successful antiangiogenic therapy of giant cell angioblastoma with interferon alfa 2b: report of 2 cases. Pediatrics 2002;109:E37.
-
(2002)
Pediatrics
, vol.109
-
-
Marler, J.J.1
Rubin, J.B.2
Trede, N.S.3
-
209
-
-
0035134688
-
Interferon in oncological practice. review of interferon biology, clinical applications, and toxicities
-
Jonasch E., and Haluska F.G. Interferon in oncological practice. review of interferon biology, clinical applications, and toxicities. Oncologist 6 (2001) 34-55
-
(2001)
Oncologist
, vol.6
, pp. 34-55
-
-
Jonasch, E.1
Haluska, F.G.2
-
210
-
-
0032555937
-
Inhibition of angiogenesis by interleukin 4
-
Volpert O.V., Fong T., Koch A.E., et al. Inhibition of angiogenesis by interleukin 4. J Exp Med 188 (1998) 1039-1046
-
(1998)
J Exp Med
, vol.188
, pp. 1039-1046
-
-
Volpert, O.V.1
Fong, T.2
Koch, A.E.3
-
211
-
-
0034652459
-
Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12
-
Duda D.G., Sunamura M., Lozonschi L., et al. Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12. Cancer Res 60 (2000) 1111-1116
-
(2000)
Cancer Res
, vol.60
, pp. 1111-1116
-
-
Duda, D.G.1
Sunamura, M.2
Lozonschi, L.3
-
212
-
-
0035915810
-
Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer
-
Oshikawa K., Rakhmilevich A.L., Shi F., et al. Interleukin 12 gene transfer into skin distant from the tumor site elicits antimetastatic effects equivalent to local gene transfer. Hum Gene Ther 12 (2001) 149-160
-
(2001)
Hum Gene Ther
, vol.12
, pp. 149-160
-
-
Oshikawa, K.1
Rakhmilevich, A.L.2
Shi, F.3
-
213
-
-
0032787604
-
Regulation of tumor growth and metastasis by interleukin-10: the melanoma experience
-
Huang S., Ullrich S.E., and Bar-Eli M. Regulation of tumor growth and metastasis by interleukin-10: the melanoma experience. J Interferon Cytokine Res 19 (1999) 697-703
-
(1999)
J Interferon Cytokine Res
, vol.19
, pp. 697-703
-
-
Huang, S.1
Ullrich, S.E.2
Bar-Eli, M.3
-
214
-
-
0030717692
-
Tissue inhibitors of metalloproteinases: structure, regulation and biological functions
-
Gomez D.E., Alonso D.F., Yoshiji H., et al. Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 74 (1997) 111-122
-
(1997)
Eur J Cell Biol
, vol.74
, pp. 111-122
-
-
Gomez, D.E.1
Alonso, D.F.2
Yoshiji, H.3
-
215
-
-
0032816628
-
Inhibition of endothelial cell migration by gene transfer of tissue inhibitor of metalloproteinases-1
-
Fernandez H.A., Kallenbach K., Seghezzi G., et al. Inhibition of endothelial cell migration by gene transfer of tissue inhibitor of metalloproteinases-1. J Surg Res 82 (1999) 156-162
-
(1999)
J Surg Res
, vol.82
, pp. 156-162
-
-
Fernandez, H.A.1
Kallenbach, K.2
Seghezzi, G.3
-
216
-
-
0027383944
-
Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation
-
Murphy A.N., Unsworth E.J., and Stetler-Stevenson W.G. Tissue inhibitor of metalloproteinases-2 inhibits bFGF-induced human microvascular endothelial cell proliferation. J Cell Physiol 157 (1993) 351-358
-
(1993)
J Cell Physiol
, vol.157
, pp. 351-358
-
-
Murphy, A.N.1
Unsworth, E.J.2
Stetler-Stevenson, W.G.3
-
217
-
-
0036839094
-
Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model
-
Spurbeck W.W., Ng C.Y., Strom T.S., et al. Enforced expression of tissue inhibitor of matrix metalloproteinase-3 affects functional capillary morphogenesis and inhibits tumor growth in a murine tumor model. Blood 100 (2002) 3361-3368
-
(2002)
Blood
, vol.100
, pp. 3361-3368
-
-
Spurbeck, W.W.1
Ng, C.Y.2
Strom, T.S.3
-
218
-
-
0036831302
-
The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells
-
Hajitou A., Grignet C., Devy L., et al. The antitumoral effect of endostatin and angiostatin is associated with a down-regulation of vascular endothelial growth factor expression in tumor cells. FASEB J 16 (2002) 1802-1804
-
(2002)
FASEB J
, vol.16
, pp. 1802-1804
-
-
Hajitou, A.1
Grignet, C.2
Devy, L.3
-
219
-
-
0037372436
-
Angiostatin selectively inhibits signaling by hepatocyte growth factor in endothelial and smooth muscle cells
-
Wajih N., and Sane D.C. Angiostatin selectively inhibits signaling by hepatocyte growth factor in endothelial and smooth muscle cells. Blood 101 (2003) 1857-1863
-
(2003)
Blood
, vol.101
, pp. 1857-1863
-
-
Wajih, N.1
Sane, D.C.2
-
220
-
-
17444390815
-
Multiple forms of angiostatin induce apoptosis in endothelial cells
-
Lucas R., Holmgren L., Garcia I., et al. Multiple forms of angiostatin induce apoptosis in endothelial cells. Blood 92 (1998) 4730-4741
-
(1998)
Blood
, vol.92
, pp. 4730-4741
-
-
Lucas, R.1
Holmgren, L.2
Garcia, I.3
-
221
-
-
0035810936
-
Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin
-
Moser T.L., Kenan D.J., Ashley T.A., et al. Endothelial cell surface F1-F0 ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci USA 98 (2001) 6656-6661
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6656-6661
-
-
Moser, T.L.1
Kenan, D.J.2
Ashley, T.A.3
-
222
-
-
0033014037
-
Angiostatin binds ATP synthase on the surface of human endothelial cells
-
Moser T.L., Stack M.S., Asplin I., et al. Angiostatin binds ATP synthase on the surface of human endothelial cells. Proc Natl Acad Sci USA 96 (1999) 2811-2816
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2811-2816
-
-
Moser, T.L.1
Stack, M.S.2
Asplin, I.3
-
223
-
-
0037008721
-
Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1
-
Kim Y.M., Hwang S., Kim Y.M., et al. Endostatin blocks vascular endothelial growth factor-mediated signaling via direct interaction with KDR/Flk-1. J Biol Chem 277 (2002) 27872-27879
-
(2002)
J Biol Chem
, vol.277
, pp. 27872-27879
-
-
Kim, Y.M.1
Hwang, S.2
Kim, Y.M.3
-
224
-
-
0036584733
-
Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin
-
Urbich C., Reissner A., Chavakis E., et al. Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin. FASEB J 16 (2002) 706-708
-
(2002)
FASEB J
, vol.16
, pp. 706-708
-
-
Urbich, C.1
Reissner, A.2
Chavakis, E.3
-
225
-
-
0035970051
-
Interaction of endostatin with integrins implicated in angiogenesis
-
Rehn M., Veikkola T., Kukk-Valdre E., et al. Interaction of endostatin with integrins implicated in angiogenesis. Proc Natl Acad Sci USA 98 (2001) 1024-1029
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 1024-1029
-
-
Rehn, M.1
Veikkola, T.2
Kukk-Valdre, E.3
-
226
-
-
0032536859
-
Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution
-
Hohenester E., Sasaki T., Olsen B.R., et al. Crystal structure of the angiogenesis inhibitor endostatin at 1.5 A resolution. EMBO J 17 (1998) 1656-1664
-
(1998)
EMBO J
, vol.17
, pp. 1656-1664
-
-
Hohenester, E.1
Sasaki, T.2
Olsen, B.R.3
-
227
-
-
0034307327
-
Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase
-
Kim Y.M., Jang J.W., Lee O.H., et al. Endostatin inhibits endothelial and tumor cellular invasion by blocking the activation and catalytic activity of matrix metalloproteinase. Cancer Res 60 (2000) 5410-5413
-
(2000)
Cancer Res
, vol.60
, pp. 5410-5413
-
-
Kim, Y.M.1
Jang, J.W.2
Lee, O.H.3
-
228
-
-
0033597130
-
Endostatin induces endothelial cell apoptosis
-
Dhanabal M., Ramchandran R., Waterman M.J., et al. Endostatin induces endothelial cell apoptosis. J Biol Chem 274 (1999) 11721-11726
-
(1999)
J Biol Chem
, vol.274
, pp. 11721-11726
-
-
Dhanabal, M.1
Ramchandran, R.2
Waterman, M.J.3
-
229
-
-
33947732977
-
Angiogenesis: an organizing principle for drug discovery?
-
Folkman J. Angiogenesis: an organizing principle for drug discovery?. Nat Rev Drug Discov 6 (2007) 273-286
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 273-286
-
-
Folkman, J.1
-
230
-
-
36049037819
-
Bevacizumab plus irinotecan in recurrent glioblastoma multiforme
-
Vredenburgh J.J., Desjardins A., Herndon II J.E., et al. Bevacizumab plus irinotecan in recurrent glioblastoma multiforme. J Clin Oncol 25 (2007) 4722-4729
-
(2007)
J Clin Oncol
, vol.25
, pp. 4722-4729
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon II, J.E.3
-
231
-
-
33646675851
-
MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy
-
Pope W.B., Lai A., Nghiemphu P., et al. MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy. Neurology 66 (2006) 1258-1260
-
(2006)
Neurology
, vol.66
, pp. 1258-1260
-
-
Pope, W.B.1
Lai, A.2
Nghiemphu, P.3
-
232
-
-
67650769211
-
Bevacizumab plus irinotecan therapy in relapsed, heavily pre-treated malignant glioma: A case series
-
Friedland D.M., Ali S.A., Ahmad A., et al. Bevacizumab plus irinotecan therapy in relapsed, heavily pre-treated malignant glioma: A case series. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 12500
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 12500
-
-
Friedland, D.M.1
Ali, S.A.2
Ahmad, A.3
-
233
-
-
0033897173
-
A phase II study of temozolomide vs. Procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung W.K., Albright R.E., Olson J., et al. A phase II study of temozolomide vs. Procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 83 (2000) 588-593
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.K.1
Albright, R.E.2
Olson, J.3
-
234
-
-
33744513575
-
®), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature
-
®), a dual-action inhibitor that targets RAF/MEK/ERK pathway in tumor cells and tyrosine kinases VEGFR/PDGFR in tumor vasculature. Methods Enzymol 407 (2005) 597-612
-
(2005)
Methods Enzymol
, vol.407
, pp. 597-612
-
-
Adnane, L.1
Trail, P.A.2
Taylor, I.3
-
235
-
-
36849058341
-
A phase I trial of sorafenib (BAY 43-9006) for patients with recurrent or progressive malignant glioma (NABTT 0401)
-
Nabors L.B., Rosenfeld M., Chamberlain M., et al. A phase I trial of sorafenib (BAY 43-9006) for patients with recurrent or progressive malignant glioma (NABTT 0401). J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2058
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2058
-
-
Nabors, L.B.1
Rosenfeld, M.2
Chamberlain, M.3
-
236
-
-
33846149645
-
AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients
-
Batchelor T.T., Sorensen A.G., di Tomaso E., et al. AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients. Cancer Cell 11 (2007) 83-95
-
(2007)
Cancer Cell
, vol.11
, pp. 83-95
-
-
Batchelor, T.T.1
Sorensen, A.G.2
di Tomaso, E.3
-
237
-
-
36549065256
-
A phase II trial of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma
-
Batchelor T., Sorensen A.G., Ancukiewicz M., et al. A phase II trial of AZD2171 (cediranib), an oral pan-VEGF receptor tyrosine kinase inhibitor, in patients with recurrent glioblastoma. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2001
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2001
-
-
Batchelor, T.1
Sorensen, A.G.2
Ancukiewicz, M.3
-
238
-
-
0033947625
-
New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis
-
Bold G., Altmann K.H., Frei J., et al. New anilinophthalazines as potent and orally well absorbed inhibitors of the VEGF receptor tyrosine kinases useful as antagonists of tumor-driven angiogenesis. J Med Chem 43 (2000) 2310-2323
-
(2000)
J Med Chem
, vol.43
, pp. 2310-2323
-
-
Bold, G.1
Altmann, K.H.2
Frei, J.3
-
239
-
-
0034655182
-
PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration
-
Wood J.M., Bold G., Buchdunger E., et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res 60 (2000) 2178-2189
-
(2000)
Cancer Res
, vol.60
, pp. 2178-2189
-
-
Wood, J.M.1
Bold, G.2
Buchdunger, E.3
-
240
-
-
36849013254
-
Phase I trial of imatinib mesylate, hydroxyurea and vatalanib for patients with recurrent glioblastoma multiforme (GBM)
-
Sathornsumetee S., Rich J.N., Vredenburgh J.J., et al. Phase I trial of imatinib mesylate, hydroxyurea and vatalanib for patients with recurrent glioblastoma multiforme (GBM). J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2027
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2027
-
-
Sathornsumetee, S.1
Rich, J.N.2
Vredenburgh, J.J.3
-
241
-
-
3142774878
-
AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity
-
Traxler P., Allegrini P.R., Brandt R., et al. AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity. Cancer Res 64 (2004) 4931-4941
-
(2004)
Cancer Res
, vol.64
, pp. 4931-4941
-
-
Traxler, P.1
Allegrini, P.R.2
Brandt, R.3
-
242
-
-
28044436878
-
A phase I study of AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases, in recurrent GBM patients
-
Reardon D., Cloughesy T., Conrad C., et al. A phase I study of AEE788, a novel multitargeted inhibitor of ErbB and VEGF receptor family tyrosine kinases, in recurrent GBM patients. J Clin Oncol (Meeting Abstracts) 23 16 Suppl. (2005) 3063
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.16 SUPPL
, pp. 3063
-
-
Reardon, D.1
Cloughesy, T.2
Conrad, C.3
-
243
-
-
33847359256
-
Targeting malignant glioma survival signalling to improve clinical outcomes
-
Wong M.L., Kaye A.H., and Hovens C.M. Targeting malignant glioma survival signalling to improve clinical outcomes. J Clin Neurosci 14 (2007) 301-308
-
(2007)
J Clin Neurosci
, vol.14
, pp. 301-308
-
-
Wong, M.L.1
Kaye, A.H.2
Hovens, C.M.3
-
244
-
-
21044431575
-
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
-
Chang S.M., Wen P., Cloughesy T., et al. Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. Invest New Drugs 23 (2005) 357-361
-
(2005)
Invest New Drugs
, vol.23
, pp. 357-361
-
-
Chang, S.M.1
Wen, P.2
Cloughesy, T.3
-
245
-
-
23944453425
-
Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study
-
Galanis E., Buckner J.C., Maurer M.J., et al. Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. J Clin Oncol 23 (2005) 5294-5304
-
(2005)
J Clin Oncol
, vol.23
, pp. 5294-5304
-
-
Galanis, E.1
Buckner, J.C.2
Maurer, M.J.3
-
246
-
-
33847402740
-
A pilot study to assess the tolerability and efficacy of RAD-001 (everolimus) with gefitinib in patients with recurrent glioblastoma multiforme (GBM)
-
Nguyen TD, Lassman AB, Lis E, et al. A pilot study to assess the tolerability and efficacy of RAD-001 (everolimus) with gefitinib in patients with recurrent glioblastoma multiforme (GBM). J Clin Oncol (Meeting Abstracts), 2006;24:1507.
-
(2006)
J Clin Oncol (Meeting Abstracts)
, vol.24
, pp. 1507
-
-
Nguyen, T.D.1
Lassman, A.B.2
Lis, E.3
-
248
-
-
67650781740
-
A phase I trial using the proteasome inhibitor bortezomib and concurrent temazolomide and radiotherapy for high grade gliomas
-
Dicker A., Werner-Wasik M., Machtay M., et al. A phase I trial using the proteasome inhibitor bortezomib and concurrent temazolomide and radiotherapy for high grade gliomas. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2061
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2061
-
-
Dicker, A.1
Werner-Wasik, M.2
Machtay, M.3
-
249
-
-
23844521568
-
The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts
-
Graff J.R., McNulty A.M., Hanna K.R., et al. The protein kinase Cbeta-selective inhibitor, Enzastaurin (LY317615.HCl), suppresses signaling through the AKT pathway, induces apoptosis, and suppresses growth of human colon cancer and glioblastoma xenografts. Cancer Res 65 (2005) 7462-7469
-
(2005)
Cancer Res
, vol.65
, pp. 7462-7469
-
-
Graff, J.R.1
McNulty, A.M.2
Hanna, K.R.3
-
250
-
-
0036137647
-
Antiangiogenic effects of a protein kinase Cbeta-selective small molecule
-
Teicher B.A., Alvarez E., Menon K., et al. Antiangiogenic effects of a protein kinase Cbeta-selective small molecule. Cancer Chemother Pharmacol 49 (2002) 69-77
-
(2002)
Cancer Chemother Pharmacol
, vol.49
, pp. 69-77
-
-
Teicher, B.A.1
Alvarez, E.2
Menon, K.3
-
251
-
-
33646555670
-
Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas
-
Fine H.A., Kim L., Royce C., et al. Results from phase II trial of enzastaurin (LY317615) in patients with recurrent high grade gliomas. J Clin Oncol (Meeting Abstracts) 23 16 Suppl. (2005) 1504
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.16 SUPPL
, pp. 1504
-
-
Fine, H.A.1
Kim, L.2
Royce, C.3
-
252
-
-
34848883049
-
Phase I/II study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme (GBM) or gliosarcoma
-
Butowski N.A., Lamborn K., Chang S., et al. Phase I/II study of enzastaurin plus temozolomide during and following radiation therapy in patients with newly diagnosed glioblastoma multiforme (GBM) or gliosarcoma. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 12511
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 12511
-
-
Butowski, N.A.1
Lamborn, K.2
Chang, S.3
-
253
-
-
0035195019
-
Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications
-
Gupta D., Treon S.P., Shima Y., et al. Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: therapeutic applications. Leukemia 15 (2001) 1950-1961
-
(2001)
Leukemia
, vol.15
, pp. 1950-1961
-
-
Gupta, D.1
Treon, S.P.2
Shima, Y.3
-
254
-
-
33646260913
-
Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells
-
Tamilarasan K.P., Kolluru G.K., Rajaram M., et al. Thalidomide attenuates nitric oxide mediated angiogenesis by blocking migration of endothelial cells. BMC Cell Biol 7 (2006) 17
-
(2006)
BMC Cell Biol
, vol.7
, pp. 17
-
-
Tamilarasan, K.P.1
Kolluru, G.K.2
Rajaram, M.3
-
255
-
-
0033954292
-
Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas
-
Fine H.A., Figg W.D., Jaeckle K., et al. Phase II trial of the antiangiogenic agent thalidomide in patients with recurrent high-grade gliomas. J Clin Oncol 18 (2000) 708-715
-
(2000)
J Clin Oncol
, vol.18
, pp. 708-715
-
-
Fine, H.A.1
Figg, W.D.2
Jaeckle, K.3
-
256
-
-
0037811745
-
Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas
-
Fine H.A., Wen P.Y., Maher E.A., et al. Phase II trial of thalidomide and carmustine for patients with recurrent high-grade gliomas. J Clin Oncol 21 (2003) 2299-2304
-
(2003)
J Clin Oncol
, vol.21
, pp. 2299-2304
-
-
Fine, H.A.1
Wen, P.Y.2
Maher, E.A.3
-
257
-
-
67650771897
-
Phase II trial of thalidomide in combination with irinotecan in adults with recurrent glioblastoma multiforme
-
Puduvalli V.K., Giglio P., Groves M.D., et al. Phase II trial of thalidomide in combination with irinotecan in adults with recurrent glioblastoma multiforme. J Clin Oncol (Meeting Abstracts) 23 16 Suppl. (2005) 1524
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.16 SUPPL
, pp. 1524
-
-
Puduvalli, V.K.1
Giglio, P.2
Groves, M.D.3
-
258
-
-
13444256401
-
Efficacy of lenalidomide in myelodysplastic syndromes
-
List A., Kurtin S., Roe D.J., et al. Efficacy of lenalidomide in myelodysplastic syndromes. N Engl J Med 352 (2005) 549-557
-
(2005)
N Engl J Med
, vol.352
, pp. 549-557
-
-
List, A.1
Kurtin, S.2
Roe, D.J.3
-
259
-
-
37249075870
-
A Phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors
-
Fine H.A., Kim L., Albert P.S., et al. A Phase I trial of lenalidomide in patients with recurrent primary central nervous system tumors. Clin Cancer Res 13 (2007) 7101-7106
-
(2007)
Clin Cancer Res
, vol.13
, pp. 7101-7106
-
-
Fine, H.A.1
Kim, L.2
Albert, P.S.3
-
260
-
-
0036792055
-
Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance
-
Ma L., del Soldato P., and Wallace J.L. Divergent effects of new cyclooxygenase inhibitors on gastric ulcer healing: Shifting the angiogenic balance. Proc Natl Acad Sci USA 99 (2002) 13243-13247
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13243-13247
-
-
Ma, L.1
del Soldato, P.2
Wallace, J.L.3
-
261
-
-
34249308965
-
Phase I/II trial of twice-daily temozolomide and celecoxib for treatment of relapsed malignant glioma: Final data
-
Pannullo S.C., Burton J., Serventi J., et al. Phase I/II trial of twice-daily temozolomide and celecoxib for treatment of relapsed malignant glioma: Final data. J Clin Oncol (Meeting Abstracts) 24 18 Suppl. (2006) 1519
-
(2006)
J Clin Oncol (Meeting Abstracts)
, vol.24
, Issue.18 SUPPL
, pp. 1519
-
-
Pannullo, S.C.1
Burton, J.2
Serventi, J.3
-
262
-
-
0025343857
-
Growth inhibitory effects of interferon-beta but not interferon-alpha on human glioma cells: correlation of receptor binding, 2′, 5′-oligoadenylate synthetase and protein kinase activity
-
Rosenblum M.G., Yung W.K., Kelleher P.J., et al. Growth inhibitory effects of interferon-beta but not interferon-alpha on human glioma cells: correlation of receptor binding, 2′, 5′-oligoadenylate synthetase and protein kinase activity. J Interferon Res 10 (1990) 141-151
-
(1990)
J Interferon Res
, vol.10
, pp. 141-151
-
-
Rosenblum, M.G.1
Yung, W.K.2
Kelleher, P.J.3
-
263
-
-
0023200679
-
Antitumor effect of recombinant murine interferon-beta against mouse malignant glioma
-
Kuroki M., Tanaka R., Suzuki Y., et al. Antitumor effect of recombinant murine interferon-beta against mouse malignant glioma. J Interferon Res 7 (1987) 301-311
-
(1987)
J Interferon Res
, vol.7
, pp. 301-311
-
-
Kuroki, M.1
Tanaka, R.2
Suzuki, Y.3
-
264
-
-
0033902039
-
Efficient inhibition of in vivo human malignant glioma growth and angiogenesis by interferon-beta treatment at early stage of tumor development
-
Hong Y.K., Chung D.S., Joe Y.A., et al. Efficient inhibition of in vivo human malignant glioma growth and angiogenesis by interferon-beta treatment at early stage of tumor development. Clin Cancer Res 6 (2000) 3354-3360
-
(2000)
Clin Cancer Res
, vol.6
, pp. 3354-3360
-
-
Hong, Y.K.1
Chung, D.S.2
Joe, Y.A.3
-
265
-
-
0029075603
-
Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas
-
Singh R.K., Gutman M., Bucana C.D., et al. Interferons alpha and beta down-regulate the expression of basic fibroblast growth factor in human carcinomas. Proc Natl Acad Sci USA 92 (1995) 4562-4566
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4562-4566
-
-
Singh, R.K.1
Gutman, M.2
Bucana, C.D.3
-
266
-
-
40849090265
-
A phase II study of temozolomide plus pegylated interferon alfa-2b for recurrent anaplastic glioma and glioblastoma multiforme
-
Groves M.D., Puduvalli V., Gilbert M.R., et al. A phase II study of temozolomide plus pegylated interferon alfa-2b for recurrent anaplastic glioma and glioblastoma multiforme. J Clin Oncol (Meeting Abstracts) 23 16 Suppl. (2005) 1519
-
(2005)
J Clin Oncol (Meeting Abstracts)
, vol.23
, Issue.16 SUPPL
, pp. 1519
-
-
Groves, M.D.1
Puduvalli, V.2
Gilbert, M.R.3
-
267
-
-
67649359584
-
Phase I analysis of systemic interferon alpha utilized with gliadel in adults with recurrent glioblastoma multiforme (GBM)
-
Lawson D.H., Phuphanich S., McKenzie E., et al. Phase I analysis of systemic interferon alpha utilized with gliadel in adults with recurrent glioblastoma multiforme (GBM). J Clin Oncol (Meeting Abstracts) 24 18 Suppl. (2006) 11508
-
(2006)
J Clin Oncol (Meeting Abstracts)
, vol.24
, Issue.18 SUPPL
, pp. 11508
-
-
Lawson, D.H.1
Phuphanich, S.2
McKenzie, E.3
-
268
-
-
34247895532
-
Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro
-
Loges S., Butzal M., Otten J., et al. Cilengitide inhibits proliferation and differentiation of human endothelial progenitor cells in vitro. Biochem Biophys Res Commun 357 (2007) 1016-1020
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 1016-1020
-
-
Loges, S.1
Butzal, M.2
Otten, J.3
-
269
-
-
33845628019
-
Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice
-
discussion 1312
-
Yamada S., Bu X.Y., Khankaldyyan V., et al. Effect of the angiogenesis inhibitor Cilengitide (EMD 121974) on glioblastoma growth in nude mice. Neurosurgery 59 (2006) 1304-1312 discussion 1312
-
(2006)
Neurosurgery
, vol.59
, pp. 1304-1312
-
-
Yamada, S.1
Bu, X.Y.2
Khankaldyyan, V.3
-
270
-
-
52949091008
-
Phase IIa trial of cilengitide (EMD121974) single-agent therapy in patients (pts) with recurrent glioblastoma (GBM): EMD 121974-009
-
Reardon D., Fink K., Nabors B., et al. Phase IIa trial of cilengitide (EMD121974) single-agent therapy in patients (pts) with recurrent glioblastoma (GBM): EMD 121974-009. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2002
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2002
-
-
Reardon, D.1
Fink, K.2
Nabors, B.3
-
271
-
-
56749119313
-
Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM)
-
Stupp R., Goldbrunner R., Neyns B., et al. Phase I/IIa trial of cilengitide (EMD121974) and temozolomide with concomitant radiotherapy, followed by temozolomide and cilengitide maintenance therapy in patients (pts) with newly diagnosed glioblastoma (GBM). J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2000
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2000
-
-
Stupp, R.1
Goldbrunner, R.2
Neyns, B.3
-
272
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R., Mason W.P., van den Bent M.J., et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352 (2005) 987-996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
-
273
-
-
0033864065
-
Prinomastat, a hydroxamate-based matrix metalloproteinase inhibitor. A novel pharmacological approach for tissue remodelling-related diseases
-
Scatena R. Prinomastat, a hydroxamate-based matrix metalloproteinase inhibitor. A novel pharmacological approach for tissue remodelling-related diseases. Expert Opin Investig Drugs 9 (2000) 2159-2165
-
(2000)
Expert Opin Investig Drugs
, vol.9
, pp. 2159-2165
-
-
Scatena, R.1
-
274
-
-
4243269889
-
Randomized phase II study of temozolomide (TMZ) with and without the matrix metalloprotease (MMP) inhibitor prinomastat in patients (pts) with glioblastoma multiforme (GBM) following best surgery and radiation therapy
-
abstr 100
-
Levin V., Phuphanich S., Glantz M., et al. Randomized phase II study of temozolomide (TMZ) with and without the matrix metalloprotease (MMP) inhibitor prinomastat in patients (pts) with glioblastoma multiforme (GBM) following best surgery and radiation therapy. Proc Am Soc Clin Oncol 21 (2002) abstr 100
-
(2002)
Proc Am Soc Clin Oncol
, vol.21
-
-
Levin, V.1
Phuphanich, S.2
Glantz, M.3
-
275
-
-
0037320432
-
2-Methoxyestradiol, a promising anticancer agent
-
Lakhani N.J., Sarkar M.A., Venitz J., et al. 2-Methoxyestradiol, a promising anticancer agent. Pharmacotherapy 23 (2003) 165-172
-
(2003)
Pharmacotherapy
, vol.23
, pp. 165-172
-
-
Lakhani, N.J.1
Sarkar, M.A.2
Venitz, J.3
-
276
-
-
39149097386
-
Phase II open-label, safety, pharmacokinetic and efficacy study of 2-methoxyestradiol nanocrystal colloidal dispersion administered orally to patients with recurrent glioblastoma multiforme
-
Kirkpatrick J., Desjardins A., Quinn J., et al. Phase II open-label, safety, pharmacokinetic and efficacy study of 2-methoxyestradiol nanocrystal colloidal dispersion administered orally to patients with recurrent glioblastoma multiforme. J Clin Oncol (Meeting Abstracts) 25 18 Suppl. (2007) 2065
-
(2007)
J Clin Oncol (Meeting Abstracts)
, vol.25
, Issue.18 SUPPL
, pp. 2065
-
-
Kirkpatrick, J.1
Desjardins, A.2
Quinn, J.3
-
277
-
-
14544305077
-
Combination of antiangiogenic therapy with other anticancer therapies: Results, challenges, and open questions
-
Gasparini G., Longo R., Fanelli M., et al. Combination of antiangiogenic therapy with other anticancer therapies: Results, challenges, and open questions. J Clin Oncol 23 (2005) 1295-1311
-
(2005)
J Clin Oncol
, vol.23
, pp. 1295-1311
-
-
Gasparini, G.1
Longo, R.2
Fanelli, M.3
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