Sin3 is involved in cell size control at Start in Saccharomyces cerevisiae

FEBS Journal

Volumn 276, Issue 14, 2009, Pages 3810-3824

  Stephan, Octavian ^a   Koch, Christian ^a  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

G1 cyclins; Histone deacetylase; Rpd3; Swi4; Swi6

Indexed keywords

CLN1 PROTEIN; CLN2 PROTEIN; CYCLINE; HISTONE DEACETYLASE; MUTANT PROTEIN; PCL1 PROTEIN; RPD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SBF; TRANSCRIPTION FACTOR SIN3A; UNCLASSIFIED DRUG; CLN3 PROTEIN, S CEREVISIAE; DNA BINDING PROTEIN; REPRESSOR PROTEIN; RPD3 PROTEIN, S CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEIN; SIN3 PROTEIN, S CEREVISIAE; SWI4 PROTEIN, S CEREVISIAE; SWI6 PROTEIN, S CEREVISIAE;

ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL SIZE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DAUGHTER CELL; FUNGAL STRAIN; GENE INACTIVATION; GENE INTERACTION; GENE LOCATION; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; WILD TYPE; CYTOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PROMOTER REGION; PROTEIN BINDING;

SACCHAROMYCES CEREVISIAE;

CYCLINS; DNA-BINDING PROTEINS; G1 PHASE; GENE EXPRESSION REGULATION, FUNGAL; HISTONE DEACETYLASES; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; REPRESSOR PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 67650690637     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07095.x     Document Type: Article

References (61)

1. Cross FR (1995) Starting the cell cycle: what's the point? Curr Opin Cell Biol 7, 790 797.
2. Nash R, Tokiwa G, Anand S, Erickson K Futcher AB (1988) The WHI1+ gene of Saccharomyces cerevisiae tethers cell division to cell size and is a cyclin homolog. EMBO J 7, 4335 4346.
3. Tyers M, Tokiwa G Futcher B (1993) Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins. EMBO J 12, 1955 1968.
4. Bahler J (2005) Cell-cycle control of gene expression in budding and fission yeast. Annu Rev Genet 39, 69 94. (Pubitemid 43011108)
5. Bloom J Cross FR (2007) Multiple levels of cyclin specificity in cell-cycle control. Nat Rev Mol Cell Biol 8, 149 160. (Pubitemid 46432532)
6. Mendenhall MD Hodge AE (1998) Regulation of Cdc28 cyclin-dependent protein kinase activity during the cell cycle of the yeast Saccharomyces cerevisiae. Microbiol Mol Biol Rev 62, 1191 1243. (Pubitemid 28558297)
7. Andrews BJ Herskowitz I (1989) The yeast SWI4 protein contains a motif present in developmental regulators and is part of a complex involved in cell-cycle-dependent transcription. Nature 342, 830 833. (Pubitemid 20023822)
8. Breeden L Nasmyth K (1987) Similarity between cell-cycle genes of budding yeast and fission yeast and the Notch gene of Drosophila. Nature 329, 651 654. (Pubitemid 17140120)
9. Koch C, Moll T, Neuberg M, Ahorn H Nasmyth K (1993) A role for the transcription factors Mbp1 and Swi4 in progression from G1 to S phase. Science 261, 1551 1557.
10. Iyer VR, Horak CE, Scafe CS, Botstein D, Snyder M Brown PO (2001) Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF. Nature 409, 533 538. (Pubitemid 32144361)
11. Lowndes NF Johnston LH (1992) Parallel pathways of cell cycle-regulated gene expression. Trends Genet 8, 79 81.
12. Pizzagalli A, Valsasnini P, Plevani P Lucchini G (1988) DNA polymerase I gene of Saccharomyces cerevisiae: nucleotide sequence, mapping of a temperature-sensitive mutation, and protein homology with other DNA polymerases. Proc Natl Acad Sci USA 85, 3772 3776.
13. Nasmyth K Dirick L (1991) The role of SWI4 and SWI6 in the activity of G1 cyclins in yeast. Cell 66, 995 1013. (Pubitemid 121001732)
14. Ogas J, Andrews BJ Herskowitz I (1991) Transcriptional activation of CLN1, CLN2, and a putative new G1 cyclin (HCS26) by SWI4, a positive regulator of G1-specific transcription. Cell 66, 1015 1026. (Pubitemid 121001733)
15. Dirick L, Bohm T Nasmyth K (1995) Roles and regulation of Cln-Cdc28 kinases at the start of the cell cycle of Saccharomyces cerevisiae. EMBO J 14, 4803 4813.
16. Stern M, Jensen R Herskowitz I (1984) Five SWI genes are required for expression of the HO gene in yeast. J Mol Biol 178, 853 868. (Pubitemid 16223334)
17. Amon A, Tyers M, Futcher B Nasmyth K (1993) Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1cyclins. Cell 74, 993 1007.
18. Harrington LA Andrews BJ (1996) Binding to the yeast SwI4,6-dependent cell cycle box, CACGAAA, is cell cycle regulated in vivo. Nucleic Acids Res 24, 558 565. (Pubitemid 26085828)
19. Koch C, Schleiffer A, Ammerer G Nasmyth K (1996) Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. Genes Dev 10, 129 141.
20. Costanzo M, Nishikawa JL, Tang X, Millman JS, Schub O, Breitkreuz K, Dewar D, Rupes I, Andrews B Tyers M (2004) CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast. Cell 117, 899 913. (Pubitemid 38798856)
21. de Bruin RA, McDonald WH, Kalashnikova TI, Yates J III. Wittenberg C (2004) Cln3 activates G1-specific transcription via phosphorylation of the SBF bound repressor Whi5. Cell 117, 887 898. (Pubitemid 38798855)
22. Cooper K (2006) Rb, whi it's not just for metazoans anymore. Oncogene 25, 5228 5232. (Pubitemid 44299081)
23. Polymenis M Schmidt EV (1997) Coupling of cell division to cell growth by translational control of the G1 cyclin CLN3 in yeast. Genes Dev 11, 2522 2531. (Pubitemid 27438833)
24. Cosma MP, Panizza S Nasmyth K (2001) Cdk1 triggers association of RNA polymerase to cell cycle promoters only after recruitment of the mediator by SBF. Mol Cell 7, 1213 1220. (Pubitemid 32607355)
25. Cosma MP, Tanaka T Nasmyth K (1999) Ordered recruitment of transcription and chromatin remodeling factors to a cell cycle- and developmentally regulated promoter. Cell 97, 299 311. (Pubitemid 29214587)
26. Wijnen H Futcher B (1999) Genetic analysis of the shared role of CLN3 and BCK2 at the G(1)-S transition in Saccharomyces cerevisiae. Genetics 153, 1131 1143. (Pubitemid 29522130)
27. Manukyan A, Zhang J, Thippeswamy U, Yang J, Zavala N, Mudannayake MP, Asmussen M, Schneider C Schneider BL (2008) Ccr4 alters cell size in yeast by modulating the timing of CLN1 and CLN2 expression. Genetics 179, 345 357.
28. Mai B Breeden L (2000) CLN1 and its repression by Xbp1 are important for efficient sporulation in budding yeast. Mol Cell Biol 20, 478 487. (Pubitemid 30023089)
29. Ashe M, de Bruin RA, Kalashnikova T, McDonald WH, Yates JR III. Wittenberg C (2008) The SBF- and MBF-associated protein Msa1 is required for proper timing of G1-specific transcription in Saccharomyces cerevisiae. J Biol Chem 283, 6040 6049.
30. de Bruin RA, Kalashnikova TI, Chahwan C, McDonald WH, Wohlschlegel J, Yates J III., Russell P Wittenberg C (2006) Constraining G1-specific transcription to late G1 phase: the MBF-associated corepressor Nrm1 acts via negative feedback. Mol Cell 23, 483 496. (Pubitemid 44205489)
31. Costanzo M, Schub O Andrews B (2003) G1 transcription factors are differentially regulated in Saccharomyces cerevisiae by the Swi6-binding protein Stb1. Mol Cell Biol 23, 5064 5077. (Pubitemid 36793350)
32. Ho Y, Costanzo M, Moore L, Kobayashi R Andrews BJ (1999) Regulation of transcription at the Saccharomyces cerevisiae start transition by Stb1, a Swi6-binding protein. Mol Cell Biol 19, 5267 5278. (Pubitemid 29339886)
33. de Bruin RA, Kalashnikova TI Wittenberg C (2008) Stb1 collaborates with other regulators to modulate the G1-specific transcriptional circuit. Mol Cell Biol 28, 6919 6928.
34. Kasten MM Stillman DJ (1997) Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins. Mol Gen Genet 256, 376 386.
35. Carrozza MJ, Florens L, Swanson SK, Shia WJ, Anderson S, Yates J, Washburn MP Workman JL (2005) Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex. Biochim Biophys Acta 1731, 77 87. (Pubitemid 41712766)
36. Carrozza MJ, Li B, Florens L, Suganuma T, Swanson SK, Lee KK, Shia WJ, Anderson S, Yates J, Washburn MP et al. (2005) Histone H3 methylation by Set2 directs deacetylation of coding regions by Rpd3S to suppress spurious intragenic transcription. Cell 123, 581 592. (Pubitemid 41608462)
37. Kadosh D Struhl K (1998) Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo. Mol Cell Biol 18, 5121 5127. (Pubitemid 28388095)
38. Kasten MM, Dorland S Stillman DJ (1997) A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators. Mol Cell Biol 17, 4852 4858. (Pubitemid 27318160)
39. Robert F, Pokholok DK, Hannett NM, Rinaldi NJ, Chandy M, Rolfe A, Workman JL, Gifford DK Young RA (2004) Global position and recruitment of HATs and HDACs in the yeast genome. Mol Cell 16, 199 209. (Pubitemid 39388835)
40. Kadosh D Struhl K (1997) Repression by Ume6 involves recruitment of a complex containing Sin3 corepressor and Rpd3 histone deacetylase to target promoters. Cell 89, 365 371.
41. Kadosh D Struhl K (1998) Histone deacetylase activity of Rpd3 is important for transcriptional repression in vivo. Genes Dev 12, 797 805. (Pubitemid 28150881)
42. Kurdistani SK, Robyr D, Tavazoie S Grunstein M (2002) Genome-wide binding map of the histone deacetylase Rpd3 in yeast. Nat Genet 31, 248 254. (Pubitemid 34887589)
43. Rundlett SE, Carmen AA, Suka N, Turner BM Grunstein M (1998) Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3. Nature 392, 831 835. (Pubitemid 28225326)
44. Robyr D, Suka Y, Xenarios I, Kurdistani SK, Wang A, Suka N Grunstein M (2002) Microarray deacetylation maps determine genome-wide functions for yeast histone deacetylases. Cell 109, 437 446. (Pubitemid 34564471)
45. Jorgensen P, Nishikawa JL, Breitkreutz BJ Tyers M (2002) Systematic identification of pathways that couple cell growth and division in yeast. Science 297, 395 400. (Pubitemid 34790768)
46. Nasmyth K, Stillman D Kipling D (1987) Both positive and negative regulators of HO transcription are required for mother-cell-specific mating-type switching in yeast. Cell 48, 579 587.
47. Sternberg PW, Stern MJ, Clark I Herskowitz I (1987) Activation of the yeast HO gene by release from multiple negative controls. Cell 48, 567 577.
48. Silverstein RA Ekwall K (2005) Sin3: a flexible regulator of global gene expression and genome stability. Curr Genet 47, 1 17. (Pubitemid 40069110)
49. Washburn BK Esposito RE (2001) Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast. Mol Cell Biol 21, 2057 2069. (Pubitemid 32479628)
50. Veis J, Klug H, Koranda M Ammerer G (2007) Activation of the G2/M-specific gene CLB2 requires multiple cell cycle signals. Mol Cell Biol 27, 8364 8373. (Pubitemid 350234247)
51. Mitra D, Parnell EJ, Landon JW, Yu Y Stillman DJ (2006) SWI/SNF binding to the HO promoter requires histone acetylation and stimulates TATA-binding protein recruitment. Mol Cell Biol 26, 4095 4110. (Pubitemid 43788013)
52. Elkhaimi M, Kaadige MR, Kamath D, Jackson JC, Biliran H Jr. Lopes JM (2000) Combinatorial regulation of phospholipid biosynthetic gene expression by the UME6, SIN3 and RPD3 genes. Nucleic Acids Res 28, 3160 3167. (Pubitemid 30624107)
53. Asp P, Acosta-Alvear D, Tsikitis M, van Oevelen C Dynlacht BD (2009) E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation. Genes Dev 23, 37 53.
54. Ficarro SB, McCleland ML, Stukenberg PT, Burke DJ, Ross MM, Shabanowitz J, Hunt DF White FM (2002) Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol 20, 301 305. (Pubitemid 34205425)
55. Skotheim JM, Di Talia S, Siggia ED Cross FR (2008) Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature 454, 291 296. (Pubitemid 352009994)
56. Bean JM, Siggia ED Cross FR (2006) Coherence and timing of cell cycle start examined at single-cell resolution. Mol Cell 21, 3 14. (Pubitemid 43017844)
57. Aparicio JG, Viggiani CJ, Gibson DG Aparicio OM (2004) The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae. Mol Cell Biol 24, 4769 4780. (Pubitemid 38668043)
58. Winzeler EA, Shoemaker DD, Astromoff A, Liang H, Anderson K, Andre B, Bangham R, Benito R, Boeke JD, Bussey H et al. (1999) Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis. Science 285, 901 906. (Pubitemid 29381993)
59. Knop M, Siegers K, Pereira G, Zachariae W, Winsor B, Nasmyth K Schiebel E (1999) Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines. Yeast 15, 963 972.
60. Strahl-Bolsinger S, Hecht A, Luo K Grunstein M (1997) SIR2 and SIR4 interactions differ in core and extended telomeric heterochromatin in yeast. Genes Dev 11, 83 93. (Pubitemid 27043826)
61. Koch C, Wollmann P, Dahl M Lottspeich F (1999) A role for Ctr9p and Paf1p in the regulation G1 cyclin expression in yeast. Nucleic Acids Res 27, 2126 2134. (Pubitemid 29219241)