Development of an Antibody Hapten-Chip System for Detecting the Residues of Multiple Antibiotic Drugs

Journal of Forensic Sciences

Volumn 54, Issue 4, 2009, Pages 953-960

  Chen, Ailiang ^a,b   Wang, Guoqing ^b,c   Cao, Qin ^d   Wang, Yan ^b,c   Zhang, Zhaohui ^e   Sun, Yimin ^a,b   Wang, Hui ^b,c   Xu, Chaoyi ^e   Zhou, Qi ^e   Han, Pei ^b,c   Liu, Miao ^b,c   Yang, Yang ^b,c   Xing, Wanli ^a,b,c   Mitchelson, Keith R ^a,b,c   Cheng, Jing ^a,b,c  

^a TSINGHUA UNIVERSITY   (China)

^b NATIONAL ENGINEERING RESEARCH CENTER FOR BEIJING BIOCHIP TECHNOLOGY   (China)

^c CapitalBio Corporation   (China)

^d Neijiang Entry Exit Inspection and Quarantine Bureau   (China)

^e Beijing Entry Exit Inspection and Quarantine Bureau   (China)

Author keywords

antibiotics; chip; Forensic sciences; immunoassay; residue; sample extraction

Indexed keywords

ANTIBIOTIC AGENT; DIHYDROSTREPTOMYCIN; ENROFLOXACIN; SULFADIMIDINE; SULFAFURAZOLE; SULFAMETHOXAZOLE; SULFAMONOMETHOXINE; SULFAQUINOXALINE;

ACCURACY; ANIMAL TISSUE; ARTICLE; BIOCHIP; CONTROLLED STUDY; CROSS REACTION; DRUG CONJUGATION; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG ISOLATION; EXTRACTION; IMMUNOASSAY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIBODIES, MONOCLONAL; CHICKENS; CHROMATOGRAPHY, LIQUID; DRUG RESIDUES; HAPTENS; IMMUNOASSAY; LIVER; MASS SPECTROMETRY; MEAT PRODUCTS; MUSCLE, SKELETAL; SWINE; TISSUE ARRAY ANALYSIS;

EID: 67650689618     PISSN: 00221198     EISSN: 15564029     Source Type: Journal    
DOI: 10.1111/j.1556-4029.2009.01049.x     Document Type: Article

References (13)

1. Strasser A, Dietrich R, Usleber E, Märtlbauer E. Immunochemical rapid test for multiresidue analysis of antimicrobial drugs in milk using monoclonal antibodies and hapten-glucose oxidase conjugates. Anal Chim Acta 2003 495 : 11 9.
2. Gupta PK, Mital BK, Gupta RS. Antibiotic sensitivity pattern of various Lactobacillus acidophilus strains. Indian J Exp Biol 1995 33 : 620 1.
3. Stolker AA, Brinkman UA. Analytical strategies for residue analysis of veterinary drugs and growth-promoting agents in food-producing animals - a review. J Chromatogr A 2005 1067 : 15 53. (Pubitemid 40363389)
4. Ekins RP, Chu FW. Multianalyte microspot immunoassay - microanalytical "compact disk" of the future. Clin Chem 1991 37 : 1955 67.
5. Balachandra K, Laisupasin P, Dhepakson P, Warachit J, Jantraraksri U, Issaragrisil S, et al. Preliminary clinical evaluation of a protein chip for tumor marker serodiagnosis of various cancers. Asian Pac J Allergy Immunol 2003 21 : 171 8.
6. Urbanowska T, Mangialaio S, Hartmann C, Legay F. Development of protein microarray technology to monitor biomarkers of rheumatoid arthritis disease. Cell Biol Toxicol 2003 19 : 189 202. (Pubitemid 36975598)
7. Robinson WH, DiGennaro C, Hueber W, Haab BB, Kamachi M, Dean EJ, et al. Autoantigen microarrays for multiplex characterization of autoantibody responses. Nat Med 2002 8 : 295 301. (Pubitemid 34250109)
8. Mezzasoma L, Bacarese-Hamilton T, Di Cristina M, Rossi R, Bistoni F, Crisanti A. Antigen microarrays for serodiagnosis of infectious diseases. Clin Chem 2002 48 : 121 30.
9. Du H, Cheng J. Protein chips for high-throughput doping screening in athletes. Expert Rev Proteomics 2006 3 : 111 4.
10. Du H, Wu M, Yang W, Yuan G, Sun Y, Lu Y, et al. Development of miniaturized competitive immunoassays on a protein chip as a screening tool for drugs. Clin Chem 2005 51 : 368 75.
11. Du H, Lu Y, Yang W, Wu M, Wang J, Zhao S, et al. Preparation of steroid antibodies and parallel detection of multianabolic steroid abuse with conjugated hapten microarray. Anal Chem 2004 76 : 6166 71.
12. Knecht BG, Strasser A, Dietrich R, Martlbauer E, Niessner R, Weller MG. Automated microarray system for the simultaneous detection of antibiotics in milk. Anal Chem 2004 76 : 646 54.
13. Zuo P, Ye B. Small molecule microarrays for drug residue detection in foodstuffs. J Agric Food Chem 2006 54 : 6978 83.