-
1
-
-
33748467172
-
Xenotransplantation and ABO incompatible transplantation: The similarities they share
-
DOI 10.1016/j.transci.2006.05.007, PII S1473050206000905
-
Galili U. Xenotransplantation and ABO incompatible transplantation: the similarities they share. Transfus Apher Sci 2006;35:45-58 (Pubitemid 44354321)
-
(2006)
Transfusion and Apheresis Science
, vol.35
, Issue.1
, pp. 45-58
-
-
Galili, U.1
-
2
-
-
30544448119
-
Characteristics of protein-carbohydrate interactions as a basis for developing novel carbohydrate-based antirejection therapies
-
DOI 10.1111/j.1440-1711.2005.01373.x
-
Holgersson J, Gustafsson A, Breimer ME. Characteristics of protein-carbohydrate interactions as a basis for developing novel carbohydrate-based antirejection therapies. Immunol Cell Biol 2005;83:694-708 (Pubitemid 43083102)
-
(2005)
Immunology and Cell Biology
, vol.83
, Issue.6
, pp. 694-708
-
-
Holgersson, J.1
Gustafsson, A.2
Breimer, M.E.3
-
3
-
-
22944449007
-
Blood brothers: Carbohydrates in xenotransplantation and cancer immunotherapy
-
DOI 10.1111/j.1440-1711.2005.01367.x
-
Ramsland P. Blood brothers: carbohydrates in xenotransplantation and cancer immunotherapy. Immunol Cell Biol 2005;83:315-317 (Pubitemid 41044608)
-
(2005)
Immunology and Cell Biology
, vol.83
, Issue.4
, pp. 315-317
-
-
Ramsland, P.A.1
-
5
-
-
38949166885
-
Recent advances in pig-to-human organ and cell transplantation
-
DOI 10.1517/14712598.8.1.1
-
Cooper DK, Ezzelarab M, Hara H, Ayares D. Recent advances in pig-to-human organ and cell transplantation. Expert Opin Biol Ther 2008;8:1-4 (Pubitemid 351233718)
-
(2008)
Expert Opinion on Biological Therapy
, vol.8
, Issue.1
, pp. 1-4
-
-
Cooper, D.K.C.1
Ezzeiarab, M.2
Hara, H.3
Ayares, D.4
-
6
-
-
0027135892
-
Identification of alpha-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: Relevance to discordant xenografting in man
-
Cooper DK, Good AH, Koren E, et al. Identification of α-galactosyl and other carbohydrate epitopes that are bound by human anti-pig antibodies: relevance to discordant xenografting in man. Transpl Immunol 1993;1:198-205 (Pubitemid 2020157)
-
(1993)
Transplant Immunology
, vol.1
, Issue.3
, pp. 198-205
-
-
Cooper, D.K.C.1
Good, A.H.2
Koren, E.3
Oriol, R.4
Malcolm, A.J.5
Ippolito, R.M.6
Neethling, F.A.7
Ye, Y.8
Romano, E.9
Zuhdi, N.10
-
7
-
-
0028171348
-
Galα(1,3)Gal, the major xenoantigen(s) recognised in pigs by human natural antibodies
-
Sandrin MS, McKenzie IF. Galα(1,3)Gal, the major xenoantigen(s) recognised in pigs by human natural antibodies. Immunol Rev 1994;141:169-190
-
(1994)
Immunol Rev
, vol.141
, pp. 169-190
-
-
Sandrin, M.S.1
McKenzie, I.F.2
-
8
-
-
10344232655
-
ABO histo-blood group system-incompatible allografting
-
DOI 10.1016/j.intimp.2004.09.020, PII S1567576904003054, New Trends in Immunosuppression
-
Nydegger U, Mohacsi P, Koestner S, et al. ABO histo-blood group system-incompatible allografting. Int Immunopharmacol 2005;5:147-153 (Pubitemid 39626699)
-
(2005)
International Immunopharmacology
, vol.5
, Issue.1
, pp. 147-153
-
-
Nydegger, U.1
Mohacsi, P.2
Koestner, S.3
Kappeler, A.4
Schaffner, T.5
Carrel, T.6
-
9
-
-
0023004703
-
Destructive and protective effects of antibody on transplants in humans: Practical and theoretical considerations
-
Baldwin WM 3rd, Paul LC, Claas FH, Daha MR. Destructive and protective effects of antibody on transplants in humans: practical and theoretical considerations. Prog Clin Biol Res 1986;224:41-67
-
(1986)
Prog Clin Biol Res
, vol.224
, pp. 41-67
-
-
Baldwin III, W.M.1
Paul, L.C.2
Claas, F.H.3
Daha, M.R.4
-
10
-
-
0017079403
-
The effects of antibodies on human renal allografts
-
Porter KA. The effects of antibodies on human renal allografts. Transplant Proc 1976;8:189-197
-
(1976)
Transplant Proc
, vol.8
, pp. 189-197
-
-
Porter, K.A.1
-
11
-
-
33846590924
-
Reactivity of human natural antibodies to endothelial cells from Galα(1,3)Gal-deficient pigs
-
Baumann BC, Stussi G, Huggel K, et al. Reactivity of human natural antibodies to endothelial cells from Galα(1,3)Gal-deficient pigs. Transplantation 2007;83:193-201
-
(2007)
Transplantation
, vol.83
, pp. 193-201
-
-
Baumann, B.C.1
Stussi, G.2
Huggel, K.3
-
12
-
-
0022260876
-
Human natural anti-α-galactosyl IgG. II. The specific recognition of α(1-3)-linked galactose residues
-
Galili U, Macher BA, Buehler J, Shohet SB. Human natural anti-α-galactosyl IgG. II. The specific recognition of α(1-3)-linked galactose residues. J Exp Med 1985;162:573-582
-
(1985)
J Exp Med
, vol.162
, pp. 573-582
-
-
Galili, U.1
Macher, B.A.2
Buehler, J.3
Shohet, S.B.4
-
13
-
-
0026623093
-
Identification of carbohydrate structures that bind human antiporcine antibodies: Implications for discordant xenografting in humans
-
Good AH, Cooper DK, Malcolm AJ, et al. Identification of carbohydrate structures that bind human antiporcine antibodies: implications for discordant xenografting in humans. Transplant Proc 1992;24:559-562
-
(1992)
Transplant Proc
, vol.24
, pp. 559-562
-
-
Good, A.H.1
Cooper, D.K.2
Malcolm, A.J.3
-
14
-
-
0027517325
-
Anti-pig IgM antibodies in human serum react predominantly with Gal(α1- 3)Gal epitopes
-
DOI 10.1073/pnas.90.23.11391
-
Sandrin MS, Vaughan HA, Dabkowski PL, Mckenzie IF. Anti-pig IgM antibodies in human serum react predominantly with Gal(α 1-3)Gal epitopes. Proc Natl Acad Sci USA 1993;90:11391-11395 (Pubitemid 23354435)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.23
, pp. 11391-11395
-
-
Sandrin, M.S.1
Vaughan, H.A.2
Dabkowski, P.L.3
McKenzie, I.F.C.4
-
15
-
-
0036009120
-
Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs
-
DOI 10.1038/nbt0302-251
-
Dai Y, Vaught TD, Boone J, et al. Targeted disruption of the α1,3-galactosyltransferase gene in cloned pigs. Nat Biotechnol 2002;20:251-255 (Pubitemid 34205417)
-
(2002)
Nature Biotechnology
, vol.20
, Issue.3
, pp. 251-255
-
-
Dai, Y.1
Vaught, T.D.2
Boone, J.3
Chen, S.-H.4
Phelps, C.J.5
Ball, S.6
Monahan, J.A.7
Jobst, P.M.8
McCreath, K.J.9
Lamborn, A.E.10
Cowell-Lucero, J.L.11
Wells, K.D.12
Colman, A.13
Polejaeva, I.A.14
Ayares, D.L.15
-
16
-
-
0037039771
-
Production of α-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning
-
DOI 10.1126/science.1068228
-
Lai L, Kolber-Simonds D, Park KW, et al. Production of α-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 2002;295:1089-1092 (Pubitemid 34132242)
-
(2002)
Science
, vol.295
, Issue.5557
, pp. 1089-1092
-
-
Lai, L.1
Kolber-Simonds, D.2
Park, K.-W.3
Cheong, H.-T.4
Greenstein, J.L.5
Im, G.-S.6
Samuel, M.7
Bonk, A.8
Rieke, A.9
Day, B.N.10
Murphy, C.N.11
Carter, D.B.12
Hawley, R.J.13
Prather, R.S.14
-
17
-
-
0347367029
-
Production of α1,3-galactosyltransferase-deficient pigs
-
Phelps CJ, Koike C, Vaught TD, et al. Production of α1,3- galactosyltransferase-deficient pigs. Science 2003;299:411-414
-
(2003)
Science
, vol.299
, pp. 411-414
-
-
Phelps, C.J.1
Koike, C.2
Vaught, T.D.3
-
18
-
-
34547454753
-
Production of homozygous α-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer
-
DOI 10.1111/j.1399-3089.2007.00417.x
-
Nottle MB, Beebe LF, Harrison SJ, et al. Production of homozygous α-1,3-galactosyltransferase knockout pigs by breeding and somatic cell nuclear transfer. Xenotransplantation 2007;14:339-344 (Pubitemid 47174364)
-
(2007)
Xenotransplantation
, vol.14
, Issue.4
, pp. 339-344
-
-
Nottle, M.B.1
Beebe, L.F.S.2
Harrison, S.J.3
McIlfatrick, S.M.4
Ashman, R.J.5
O'Connell, P.J.6
Salvaris, E.J.7
Fisicaro, N.8
Pommey, S.9
Cowan, P.J.10
D'Apice, A.J.F.11
-
19
-
-
32044445822
-
The molecular basis for Galα(1,3)Gal expression in animals with a deletion of the α1,3galactosyltransferase gene
-
The iGb3S enzyme was cloned from mouse thymus and iGb3S mRNA expression was shown in certain mouse and pig tissues, which suggests that Galα(1,3)Gal epitopes are synthesized by iGb3S in GGTA1 knockout mice and possibly by pig iGb3S
-
Milland J, Christiansen D, Lazarus BD, et al. The molecular basis for Galα(1,3)Gal expression in animals with a deletion of the α1,3galactosyltransferase gene. J Immunol 2006;176:2448-54 • The iGb3S enzyme was cloned from mouse thymus and iGb3S mRNA expression was shown in certain mouse and pig tissues, which suggests that Galα(1,3)Gal epitopes are synthesized by iGb3S in GGTA1 knockout mice and possibly by pig iGb3S.
-
(2006)
J Immunol
, vol.176
, pp. 2448-2454
-
-
Milland, J.1
Christiansen, D.2
Lazarus, B.D.3
-
20
-
-
0037468446
-
Pig cells that lack the gene for α1-3 galactosyltransferase express low levels of the gal antigen
-
DOI 10.1097/01.TP.0000053615.98201.77
-
Sharma A, Naziruddin B, Cui C, et al. Pig cells that lack the gene for α1-3 galactosyltransferase express low levels of the gal antigen. Transplantation 2003;75:430-6 • This study shows that reduced levels of Galα(1,3)Gal may remain in certain pig cells lacking α1,3GT. (Pubitemid 36241133)
-
(2003)
Transplantation
, vol.75
, Issue.4
, pp. 430-436
-
-
Sharma, A.1
Naziruddin, B.2
Cui, C.3
Martin, M.J.4
Xu, H.5
Wan, H.6
Lei, Y.7
Harrison, C.8
Yin, J.9
Okabe, J.10
Mathews, C.11
Stark, A.12
Adams, C.S.13
Houtz, J.14
Wiseman, B.S.15
Byrne, G.W.16
Logan, J.S.17
-
21
-
-
30544443374
-
α1,3-galactosyltransferase knockout pigs are available for xenotransplantation: Are glycosyltransferases still relevant?
-
Milland J, Christiansen D, Sandrin MS. α1,3-galactosyltransferase knockout pigs are available for xenotransplantation: are glycosyltransferases still relevant? Immunol Cell Biol 2005;83:687-693
-
(2005)
Immunol Cell Biol
, vol.83
, pp. 687-693
-
-
Milland, J.1
Christiansen, D.2
Sandrin, M.S.3
-
22
-
-
0344331265
-
Isolation of a cDNA encoding a murine UDPgalactose:β-D-galactosyl-1, 4-N-acetyl-D-glucosaminide α-1,3-galactosyltransferase: Expression cloning by gene transfer
-
Larsen RD, Rajan VP, Ruff MM, et al. Isolation of a cDNA encoding a murine UDPgalactose:β-D-galactosyl- 1, 4-N-acetyl-D-glucosaminide α-1, 3-galactosyltransferase: expression cloning by gene transfer. Proc Natl Acad Sci USA 1989;86:8227-8231 (Pubitemid 19286032)
-
(1989)
Proceedings of the National Academy of Sciences of the United States of America
, vol.86
, Issue.21
, pp. 8227-8231
-
-
Larsen, R.D.1
Rajan, V.P.2
Ruff, M.M.3
Kukowska-Latallo, J.4
Cummings, R.D.5
Lowe, J.B.6
-
23
-
-
0036971387
-
Histidine 271 has a functional role in pig α-1, 3galactosyltransferase enzyme activity
-
DOI 10.1093/glycob/cwf092
-
Lazarus BD, Milland J, Ramsland PA, et al. Histidine 271 has a functional role in pig α-1,3galactosyltransferase enzyme activity. Glycobiology 2002;12:793-802 (Pubitemid 36150166)
-
(2002)
Glycobiology
, vol.12
, Issue.12
, pp. 793-802
-
-
Lazarus, B.D.1
Milland, J.2
Ramsland, P.A.3
Mouhtouris, E.4
Sandrin, M.S.5
-
24
-
-
0024297335
-
Man, apes, and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells
-
Galili U, Shohet SB, Kobrin E, et al. Man, apes, and Old World monkeys differ from other mammals in the expression of α-galactosyl epitopes on nucleated cells. J Biol Chem 1988;263:17755-17762
-
(1988)
J Biol Chem
, vol.263
, pp. 17755-17762
-
-
Galili, U.1
Shohet, S.B.2
Kobrin, E.3
-
25
-
-
0025264624
-
Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:β-D-Gal(1,4)-D-GlcNAc α(1,3)- galactosyltransferase cDNA
-
Larsen RD, Rivera-Marrero CA, Ernst LK, et al. Frameshift and nonsense mutations in a human genomic sequence homologous to a murine UDP-Gal:β-D-Gal(1,4)-D-GlcNAc α(1,3)-galactosyltransferase cDNA. J Biol Chem 1990;265:7055-7061
-
(1990)
J Biol Chem
, vol.265
, pp. 7055-7061
-
-
Larsen, R.D.1
Rivera-Marrero, C.A.2
Ernst, L.K.3
-
26
-
-
0034682757
-
3 synthase, that directs the synthesis of isoglobo-glycosphingolipids
-
DOI 10.1074/jbc.M002629200
-
Keusch JJ, Manzella SM, Nyame KA, et al. Expression cloning of a new member of the ABO blood group glycosyltransferases, iGb3 synthase, that directs the synthesis of isoglobo-glycosphingolipids. J Biol Chem 2000;275:25308-25314 (Pubitemid 30687027)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.33
, pp. 25308-25314
-
-
Keusch, J.J.1
Manzella, S.M.2
Nyame, K.A.3
Cummings, R.D.4
Baenziger, J.U.5
-
27
-
-
0038394491
-
Characterization of the rat α(1,3) galactosyltransferase: Evidence for two independent genes encoding glycosyltransferases that synthesize Galα(1,3)Gal by two separate glycosylation pathways
-
Taylor SG, Mckenzie IF, Sandrin MS. Characterization of the rat α(1,3) galactosyltransferase: evidence for two independent genes encoding glycosyltransferases that synthesize Galα(1,3)Gal by two separate glycosylation pathways. Glycobiology 2003;13:327-337
-
(2003)
Glycobiology
, vol.13
, pp. 327-337
-
-
Taylor, S.G.1
Mckenzie, I.F.2
Sandrin, M.S.3
-
28
-
-
49649085309
-
The anti-non-gal xenoantibody response to xenoantigens on gal knockout pig cells is encoded by a restricted number of germline progenitors
-
Kiernan K, Harnden I, Gunthart M, et al. The anti-non-gal xenoantibody response to xenoantigens on gal knockout pig cells is encoded by a restricted number of germline progenitors. Am J Transplant 2008;8:1829-1839
-
(2008)
Am J Transplant
, vol.8
, pp. 1829-1839
-
-
Kiernan, K.1
Harnden, I.2
Gunthart, M.3
-
29
-
-
38449098268
-
Studies on glycolipid antigens in small intestine and pancreas from α1,3-galactosyltransferase knockout miniature swine
-
DOI 10.1097/01.tp.0000287599.46165.15, PII 0000789020071127000018
-
Diswall M, Angstrom J, Schuurman HJ, et al. Studies on glycolipid antigens in small intestine and pancreas from α1,3-galactosyltransferase knockout miniature swine. Transplantation 2007;84:1348-1356 (Pubitemid 351339324)
-
(2007)
Transplantation
, vol.84
, Issue.10
, pp. 1348-1356
-
-
Diswall, M.1
Angstrom, J.2
Schuurman, H.-J.3
Dor, F.J.M.F.4
Rydberg, L.5
Breimer, M.E.6
-
31
-
-
48349111099
-
Humans lack iGb3 due to the absence of functional iGb3-synthase: Implications for NKT cell development and transplantation
-
Published online 15 July 2008, doi:10.1371/journal.pbio.0060172 •• This work has established that the gene encoding iGb3S is non-functional in humans. Futhermore, the findings reveal that iGb3 or poly-α-Gal glycosphingolipids produced by iGb3S are possible important xenoantigens, which are recognized by antibodies and natural killer T cells
-
Christiansen D, Milland J, Mouhtouris E, et al. Humans lack iGb3 due to the absence of functional iGb3-synthase: implications for NKT cell development and transplantation. PLoS Biol 2008;6:e172. Published online 15 July 2008, doi:10.1371/journal.pbio.0060172 •• This work has established that the gene encoding iGb3S is non-functional in humans. Futhermore, the findings reveal that iGb3 or poly-α-Gal glycosphingolipids produced by iGb3S are possible important xenoantigens, which are recognized by antibodies and natural killer T cells.
-
(2008)
PLoS Biol
, vol.6
-
-
Christiansen, D.1
Milland, J.2
Mouhtouris, E.3
-
33
-
-
34248153179
-
Crystal Structure of the Marasmius Oreades Mushroom Lectin in Complex with a Xenotransplantation Epitope
-
DOI 10.1016/j.jmb.2007.03.016, PII S0022283607003294
-
Grahn E, Askarieh G, Holmner A, et al. Crystal structure of the Marasmius oreades mushroom lectin in complex with a xenotransplantation epitope. J Mol Biol 2007;369:710-21 • A crystal structure of a mushroom lectin (MOA) with high affinity and specificity for Galα(1,3)Galβ(1,4)GlcNAc was determined in complex with the trisaccharide. The structural basis for recognition of the major xenoantigen is revealed and MOA is suggested to be useful in combination with I-B4 and antibodies in screening tissues for xenoantigens. (Pubitemid 46709914)
-
(2007)
Journal of Molecular Biology
, vol.369
, Issue.3
, pp. 710-721
-
-
Grahn, E.1
Askarieh, G.2
Holmner, A.3
Tateno, H.4
Winter, H.C.5
Goldstein, I.J.6
Krengel, U.7
-
34
-
-
33745086500
-
Carbohydrate recognition by Clostridium difficile toxin a
-
DOI 10.1038/nsmb1084, PII N1084
-
Greco A, Ho JG, Lin SJ, et al. Carbohydrate recognition by Clostridium difficile toxin A. Nat Struct Mol Biol 2006;13:460-461 (Pubitemid 43881588)
-
(2006)
Nature Structural and Molecular Biology
, vol.13
, Issue.5
, pp. 460-461
-
-
Greco, A.1
Ho, J.G.S.2
Lin, S.-J.3
Palcic, M.M.4
Rupnik, M.5
Ng, K.K.-S.6
-
35
-
-
1842450281
-
Structure and functional analysis of the fungal galectin CGL2
-
DOI 10.1016/j.str.2004.03.002, PII S0969212604000826
-
Walser PJ, Haebel PW, Kunzler M, et al. Structure and functional analysis of the fungal galectin CGL2. Structure 2004;12:689-702 (Pubitemid 38447171)
-
(2004)
Structure
, vol.12
, Issue.4
, pp. 689-702
-
-
Walser, P.J.1
Haebel, P.W.2
Kunzler, M.3
Sargent, D.4
Kues, U.5
Aebi, M.6
Ban, N.7
-
36
-
-
0029854589
-
Molecular mimicry in the recognition of glycosphingolipids by Galα3Galβ4GlcNAcβ-binding Clostridium difficile toxin A, human natural anti α-galactosyl IgG and the monoclonal antibody Gal-13: Characterization of a binding-active human glycosphingolipid, non-identical with the animal receptor
-
DOI 10.1093/glycob/6.6.599
-
Teneberg S, Lonnroth I, Torres Lopez JF, et al. Molecular mimicry in the recognition of glycosphingolipids by Galα3Galβ4GlcNAcβ-binding Clostridium difficile toxin A, human natural anti α-galactosyl IgG and the monoclonal antibody Gal-13: characterization of a binding-active human glycosphingolipid, non-identical with the animal receptor. Glycobiology 1996;6:599-609 (Pubitemid 26386373)
-
(1996)
Glycobiology
, vol.6
, Issue.6
, pp. 599-609
-
-
Teneberg, S.1
Lonnroth, I.2
Torres Lopez, J.F.3
Galili, U.4
Halvarsson, M.O.5
Angstrom, J.6
Karlsson, K.-A.7
-
37
-
-
2442452790
-
4 isolectin to αgalactosyl carbohydrate antigens in the surface phase
-
DOI 10.1111/j.1399-3089.2004.00108.x
-
Kirkeby S, Winter HC, Goldstein IJ. Comparison of the binding properties of the mushroom Marasmius oreades lectin and Griffonia simplicifolia I-B4 isolectin to αgalactosyl carbohydrate antigens in the surface phase. Xenotransplantation 2004;11:254-261 (Pubitemid 38623062)
-
(2004)
Xenotransplantation
, vol.11
, Issue.3
, pp. 254-261
-
-
Kirkeby, S.1
Winter, H.C.2
Goldstein, I.J.3
-
38
-
-
53149111089
-
Structural basis of the preferential binding for globo-series glycosphingolipids displayed by Pseudomonas aeruginosa lectin I
-
The crystal structure of the complex between Galα(1,3)Galβ(1, 4)Glc and a lectin reveals a possible mechanism for binding to iGb3 or poly-α-Gal glycosphingolipids produced by iGb3S
-
Blanchard B, Nurisso A, Hollville E, et al. Structural basis of the preferential binding for globo-series glycosphingolipids displayed by Pseudomonas aeruginosa lectin I. J Mol Biol 2008;383:837-53 • The crystal structure of the complex between Galα(1,3)Galβ(1,4)Glc and a lectin reveals a possible mechanism for binding to iGb3 or poly-α-Gal glycosphingolipids produced by iGb3S.
-
(2008)
J Mol Biol
, vol.383
, pp. 837-853
-
-
Blanchard, B.1
Nurisso, A.2
Hollville, E.3
-
39
-
-
33750375245
-
Structural studies on peanut lectin complexed with disaccharides involving different linkages: Further insights into the structure and interactions of the lectin
-
DOI 10.1107/S0907444906035712
-
Natchiar SK, Srinivas O, Mitra N, et al. Structural studies on peanut lectin complexed with disaccharides involving different linkages: further insights into the structure and interactions of the lectin. Acta Crystallogr D Biol Crystallogr 2006;62:1413-1421 (Pubitemid 44630222)
-
(2006)
Acta Crystallographica Section D: Biological Crystallography
, vol.62
, Issue.11
, pp. 1413-1421
-
-
Natchiar, S.K.1
Srinivas, O.2
Mitra, N.3
Surolia, A.4
Jayaraman, N.5
Vijayan, M.6
-
40
-
-
0037155263
-
4. X-ray crystal structure of the complex and molecular dynamics characterization of the binding site
-
DOI 10.1074/jbc.M109919200
-
Tempel W, Tschampel S, Woods RJ. The xenograft antigen bound to Griffonia simplicifolia lectin 1-B4. X-ray crystal structure of the complex and molecular dynamics characterization of the binding site. J Biol Chem 2002;277:6615-21 •• The first crystal structure of a protein (I-B4 lectin) in complex with Galα(1,3) Gal, which provided the first glimpse of a potential end-on insertion mechanism for natural antibody recognition of the major carbohydrate xenoantigen. (Pubitemid 34968462)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.8
, pp. 6615-6621
-
-
Tempel, W.1
Tschampel, S.2
Woods, R.J.3
-
41
-
-
0037155279
-
4 and molecular basis for metal binding and monosaccharide specificity
-
DOI 10.1074/jbc.M109867200
-
Lescar J, Loris R, Mitchell E, et al. Isolectins I-A and I-B of Griffonia (Bandeiraea) simplicifolia. Crystal structure of metal-free GS I-B4 and molecular basis for metal binding and monosaccharide specificity. J Biol Chem 2002;277:6608-6614 (Pubitemid 34968461)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.8
, pp. 6608-6614
-
-
Lescar, J.1
Loris, R.2
Mitchell, E.3
Gautier, C.4
Chazalet, V.5
Cox, V.6
Wyns, L.7
Perez, S.8
Breton, C.9
Imberty, A.10
-
42
-
-
36849057748
-
Carbohydrate residues downstream of the terminal Galα(1,3)Gal epitope modulate the specificity of xenoreactive antibodies
-
A demonstration that selective antibody binding of iGb3S produced glycosphingolipids was due to antibody discrimination between GlcNAc or Glc at the third position of Galα(1,3) Gal-containing carbohydrate chains. Structural models of antibodies and carbohydrate docking studies were used to predict the mechanism of binding and selective recognition of the two major Galα(1,3)Gal xenoantigens
-
Milland J, Yuriev E, Xing PX, et al. Carbohydrate residues downstream of the terminal Galα(1,3)Gal epitope modulate the specificity of xenoreactive antibodies. Immunol Cell Biol 2007;85:623-32 •• A demonstration that selective antibody binding of iGb3S produced glycosphingolipids was due to antibody discrimination between GlcNAc or Glc at the third position of Galα(1,3) Gal-containing carbohydrate chains. Structural models of antibodies and carbohydrate docking studies were used to predict the mechanism of binding and selective recognition of the two major Galα(1,3)Gal xenoantigens.
-
(2007)
Immunol Cell Biol
, vol.85
, pp. 623-632
-
-
Milland, J.1
Yuriev, E.2
Xing, P.X.3
-
43
-
-
0036665048
-
Lectin interactions with α-galactosylated xenoantigens
-
DOI 10.1034/j.1399-3089.2002.01078.x
-
Kirkeby S, Moe D. Lectin interactions with α-galactosylated xenoantigens. Xenotransplantation 2002;9:260-7 44. Imberty A, Mikros E, Koca J, et al. Computer simulation of histo-blood group oligosaccharides: energy maps of all constituting disaccharides and potential energy surfaces of 14 ABH and Lewis carbohydrate antigens. Glycoconj J 1995;12:331-349 (Pubitemid 36358950)
-
(2002)
Xenotransplantation
, vol.9
, Issue.4
, pp. 260-267
-
-
Kirkeby, S.1
Moe, D.2
-
44
-
-
0001324436
-
Use of a general purpose force-field (MM2) for the conformational analysis of the disaccharide α-D-galactopyranosyl-(1-3)- β-D-galactopyranose
-
Strotz CA, Cerezo AS. Use of a general purpose force-field (MM2) for the conformational analysis of the disaccharide α-D-galactopyranosyl-(1-3)- β-D-galactopyranose. J Carb Chem 1994;13:235-247
-
(1994)
J Carb Chem
, vol.13
, pp. 235-247
-
-
Strotz, C.A.1
Cerezo, A.S.2
-
45
-
-
0036019909
-
Solution structure of two xenoantigens: αGal-LacNAc and αGal-Lewis X
-
Corzana F, Bettler E, Herve DU, et al. Solution structure of two xenoantigens: αGal-LacNAc and αGal-Lewis X. Glycobiology 2002;12:241-250 (Pubitemid 34760069)
-
(2002)
Glycobiology
, vol.12
, Issue.4
, pp. 241-250
-
-
Corzana, F.1
Bettler, E.2
Du Penhoat, C.H.3
Tyrtysh, T.V.4
Bovin, N.V.5
Imberty, A.6
-
46
-
-
0033013096
-
Conformational analysis of an α-galactosyl trisaccharide epitope involved in hyperacute rejection upon xenotransplantation
-
DOI 10.1016/S0008-6215(98)00321-8, PII S0008621598003218
-
Li J, Ksebati MB, Zhang W, et al. Conformational analysis of an α-galactosyl trisaccharide epitope involved in hyperacute rejection upon xenotransplantation. Carbohydr Res 1999;315:76-88 (Pubitemid 29241835)
-
(1999)
Carbohydrate Research
, vol.315
, Issue.1-2
, pp. 76-88
-
-
Li, J.1
Ksebati, M.B.2
Zhang, W.3
Guo, Z.4
Wang, J.5
Yu, L.6
Fang, J.7
Wang, P.G.8
-
47
-
-
0033555274
-
3
-
DOI 10.1046/j.1432-1327.1999.00036.x
-
Otter A, Lemieux RU, Ball RG, et al. Crystal state and solution conformation of the B blood group trisaccharide α-L-Fucp-(1→2)- [α-D-Galp]-(1→3)]-β-D-Galp-OCH3. Eur J Biochem 1999;259:295-303 (Pubitemid 29030849)
-
(1999)
European Journal of Biochemistry
, vol.259
, Issue.1-2
, pp. 295-303
-
-
Otter, A.1
Lemieux, R.U.2
Ball, R.G.3
Venot, A.P.4
Hindsgaul, O.5
Bundle, D.R.6
-
48
-
-
0025708892
-
Molecular structure of 3-O- (3,6-anhydro-α-D-galactopyranosyl)- β-D-galactopyranose (neocarrabiose) in the solid state and in solution: An investigation by X-ray crystallography, n.m.r. spectroscopy, and molecular mechanics calculations
-
Lamba D, Segre AL, Glover S, et al. Molecular structure of 3-O- (3,6-anhydro-α-D-galactopyranosyl)- β-D-galactopyranose (neocarrabiose) in the solid state and in solution: an investigation by X-ray crystallography, n.m.r. spectroscopy, and molecular mechanics calculations. Carbohydr Res 1990;208:215-230
-
(1990)
Carbohydr Res
, vol.208
, pp. 215-230
-
-
Lamba, D.1
Segre, A.L.2
Glover, S.3
-
49
-
-
22944433255
-
Three-dimensional structures of carbohydrate determinants of Lewis system antigens: Implications for effective antibody targeting of cancer
-
DOI 10.1111/j.1440-1711.2005.01374.x
-
Yuriev E, Farrugia W, Scott AM, Ramsland PA. Three-dimensional structures of carbohydrate determinants of Lewis system antigens: implications for effective antibody targeting of cancer. Immunol Cell Biol 2005;83:709-717 (Pubitemid 43083103)
-
(2005)
Immunology and Cell Biology
, vol.83
, Issue.6
, pp. 709-717
-
-
Yuriev, E.1
Farrugia, W.2
Scott, A.M.3
Ramsland, P.A.4
-
50
-
-
1542572965
-
Evidence for structurally conserved recognition of the major carbohydrate xenoantigen by natural antibodies
-
Ramsland PA, Farrugia W, Yuriev E, et al. Evidence for structurally conserved recognition of the major carbohydrate xenoantigen by natural antibodies. Cell Mol Biol (Noisy-le-grand) 2003;49:307-317
-
(2003)
Cell Mol Biol (Noisy-le-grand)
, vol.49
, pp. 307-317
-
-
Ramsland, P.A.1
Farrugia, W.2
Yuriev, E.3
-
51
-
-
33745728310
-
Shapes of antibody binding sites: Qualitative and quantitative analyses based on a geomorphic classification scheme
-
Lee M, Lloyd P, Zhang X, et al. Shapes of antibody binding sites: qualitative and quantitative analyses based on a geomorphic classification scheme. J Org Chem 2006;71:5082-5092
-
(2006)
J Org Chem
, vol.71
, pp. 5082-5092
-
-
Lee, M.1
Lloyd, P.2
Zhang, X.3
-
52
-
-
3042561937
-
Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens
-
DOI 10.1016/j.jmb.2004.05.037, PII S0022283604006072
-
Ramsland PA, Farrugia W, Bradford TM, et al. Structural convergence of antibody binding of carbohydrate determinants in Lewis Y tumor antigens. J Mol Biol 2004;340:809-818 (Pubitemid 38829640)
-
(2004)
Journal of Molecular Biology
, vol.340
, Issue.4
, pp. 809-818
-
-
Ramsland, P.A.1
Farrugia, W.2
Bradford, T.M.3
Hogarth, P.M.4
Scott, A.M.5
-
53
-
-
12444291017
-
Antibody domain exchange is an immunological solution to carbohydrate cluster recognition
-
Calarese DA, Scanlan CN, Zwick MB, et al. Antibody domain exchange is an immunological solution to carbohydrate cluster recognition. Science 2003;300:2065-71
-
(2003)
Science
, vol.300
, pp. 2065-2071
-
-
Calarese, D.A.1
Scanlan, C.N.2
Zwick, M.B.3
-
54
-
-
0026319774
-
Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody fab fragment
-
Cygler M, Rose DR, Bundle DR. Recognition of a cell-surface oligosaccharide of pathogenic Salmonella by an antibody Fab fragment. Science 1991;253:442-445 (Pubitemid 21917173)
-
(1991)
Science
, vol.253
, Issue.5018
, pp. 442-445
-
-
Cygler, M.1
Rose, D.R.2
Bundle, D.R.3
-
55
-
-
48249119924
-
Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody
-
Vulliez-Le Normand B, Saul FA, Phalipon A, et al. Structures of synthetic O-antigen fragments from serotype 2a Shigella flexneri in complex with a protective monoclonal antibody. Proc Natl Acad Sci USA 2008;105:9976-9981
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9976-9981
-
-
Vulliez-Le Normand, B.1
Saul, F.A.2
Phalipon, A.3
-
56
-
-
0032572977
-
A murine model of antibody-mediated hyperacute rejection by galactose-α(1,3) galactose antibodies in Gal o/o mice
-
McKenzie IF, Li YQ, Patton K, et al. A murine model of antibody-mediated hyperacute rejection by galactose-α(1,3) galactose antibodies in Gal o/o mice. Transplantation 1998;66:754-763
-
(1998)
Transplantation
, vol.66
, pp. 754-763
-
-
McKenzie, I.F.1
Li, Y.Q.2
Patton, K.3
-
57
-
-
17844409063
-
Characteristics of immunoglobulin gene usage of the xenoantibody binding to gal-α(1,3)gal target antigens in the gal knockout mouse
-
Nozawa S, Xing PX, Wu GD, et al. Characteristics of immunoglobulin gene usage of the xenoantibody binding to gal-α(1,3)gal target antigens in the gal knockout mouse. Transplantation 2001;72:147-155
-
(2001)
Transplantation
, vol.72
, pp. 147-155
-
-
Nozawa, S.1
Xing, P.X.2
Wu, G.D.3
-
58
-
-
46049119803
-
Antibody-ligand docking: Insights into peptide-carbohydrate mimicry
-
Yuriev E, Sandrin MS, Ramsland PA. Antibody-ligand docking: insights into peptide-carbohydrate mimicry. Mol Simulation 2008;34:461-468
-
(2008)
Mol Simulation
, vol.34
, pp. 461-468
-
-
Yuriev, E.1
Sandrin, M.S.2
Ramsland, P.A.3
-
60
-
-
62849111658
-
Complement activation and coagulation in xenotransplantation
-
Cowan PJ, d'Apice AJ. Complement activation and coagulation in xenotransplantation. Immunol Cell Biol 2009;87:203-208
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 203-208
-
-
Cowan, P.J.1
D'Apice, A.J.2
-
61
-
-
34447621251
-
Gal knockout pigs: Any more carbohydrates?
-
Sandrin MS. Gal knockout pigs: any more carbohydrates? Transplantation 2007;84:8-9
-
(2007)
Transplantation
, vol.84
, pp. 8-9
-
-
Sandrin, M.S.1
-
62
-
-
0142059844
-
Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid
-
DOI 10.1073/pnas.2131556100
-
Tangvoranuntakul P, Gagneux P, Diaz S, et al. Human uptake and incorporation of an immunogenic nonhuman dietary sialic acid. Proc Natl Acad Sci USA 2003;100:12045-50 •• A demonstration that small amounts of Neu5Gc (a non-human sialic acid) could be incorporated into human cells, but cannot be synthesized unlike all other mammals including our closest relative, the chimpanzee. Comparison of human and chimpanzee sera revealed that most humans have natural antibodies to Neu5Gc. Furthermore, humans were shown to have significantly higher levels of Galα(1,3)Gal antibodies than chimpanzees. (Pubitemid 37271512)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.21
, pp. 12045-12050
-
-
Tangvoranuntakul, P.1
Gagneux, P.2
Diaz, S.3
Bardor, M.4
Varki, N.5
Varki, A.6
Muchmore, E.7
-
63
-
-
0029665037
-
Thomsen-Friedenreich and PK antigens in pig-to-human xenotransplantation
-
Cairns T, Lee J, Goldberg LC, et al. Thomsen-Friedenreich and PK antigens in pig-to-human xenotransplantation. Transplant Proc 1996;28:795-796
-
(1996)
Transplant Proc
, vol.28
, pp. 795-796
-
-
Cairns, T.1
Lee, J.2
Goldberg, L.C.3
-
64
-
-
0033847675
-
4Cer, with terminal Gal(β1-4)Gal, a xenoepitope recognized by human natural antibodies
-
Bouhours D, Liaigre J, Naulet J, et al. A novel pentaglycosylceramide in ostrich liver, IV4-β-Gal-nLc4Cer, with terminal Gal(β1-4)Gal, a xenoepitope recognized by human natural antibodies. Glycobiology 2000;10:857-864 (Pubitemid 30673920)
-
(2000)
Glycobiology
, vol.10
, Issue.9
, pp. 857-864
-
-
Bouhours, D.1
Liaigre, J.2
Naulet, J.3
Bovin, N.V.4
Bouhours, J.-F.5
-
65
-
-
0034111710
-
The target antigens of naturally occurring human anti-β-galactose IgG are cryptic on porcine aortic endothelial cells
-
DOI 10.1034/j.1399-3089.2000.00041.x
-
Lucq J, Tixier D, Guinault AM, et al. The target antigens of naturally occurring human anti-β-galactose IgG are cryptic on porcine aortic endothelial cells. Xenotransplantation 2000;7:3-13 (Pubitemid 30253152)
-
(2000)
Xenotransplantation
, vol.7
, Issue.1
, pp. 3-13
-
-
Lucq, J.1
Tixier, D.2
Guinault, A.M.3
Greffard, A.4
Loisance, D.5
Pilatte, Y.6
-
66
-
-
33747627375
-
Recognition of a carbohydrate xenoepitope by human NKRP1A (CD161)
-
DOI 10.1111/j.1399-3089.2006.00332.x
-
Christiansen D, Mouhtouris E, Milland J, et al. Recognition of a carbohydrate xenoepitope by human NKRP1A (CD161). Xenotransplantation 2006;13:440-446 (Pubitemid 44265713)
-
(2006)
Xenotransplantation
, vol.13
, Issue.5
, pp. 440-446
-
-
Christiansen, D.1
Mouhtouris, E.2
Milland, J.3
Zingoni, A.4
Santoni, A.5
Sandrin, M.S.6
-
67
-
-
34247565506
-
Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins
-
DOI 10.1038/nature05816, PII NATURE05816
-
Varki A. Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins. Nature 2007;446:1023-1029 (Pubitemid 46676064)
-
(2007)
Nature
, vol.446
, Issue.7139
, pp. 1023-1029
-
-
Varki, A.1
-
68
-
-
0036872920
-
Anti-N-glycolylneuraminic acid antibodies identified in healthy human serum
-
DOI 10.1034/j.1399-3089.2002.02138.x
-
Zhu A, Hurst R. Anti-N-glycolylneuraminic acid antibodies identified in healthy human serum. Xenotransplantation 2002;9:376-381 (Pubitemid 36358933)
-
(2002)
Xenotransplantation
, vol.9
, Issue.6
, pp. 376-381
-
-
Zhu, A.1
Hurst, R.2
-
69
-
-
2442538314
-
Are N-glycolylneuraminic acid (Hanganutziu-Deicher) antigens important in pig-to-human xenotransplantation?
-
Miwa Y, Kobayashi T, Nagasaka T, et al. Are N-glycolylneuraminic acid (Hanganutziu-Deicher) antigens important in pig-to-human xenotransplantation? Xenotransplantation 2004;11:247-253
-
(2004)
Xenotransplantation
, vol.11
, pp. 247-253
-
-
Miwa, Y.1
Kobayashi, T.2
Nagasaka, T.3
-
70
-
-
53049100695
-
Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: Potential implications for disease
-
Padler-Karavani V, Yu H, Cao H, et al. Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease. Glycobiology 2008;18:818-830
-
(2008)
Glycobiology
, vol.18
, pp. 818-830
-
-
Padler-Karavani, V.1
Yu, H.2
Cao, H.3
-
71
-
-
0017665490
-
Antigen of "serum sickness" type of heterophile antibodies in human sera: Indentification as gangliosides with N-glycolylneuraminic acid
-
Higashi H, Naiki M, Matuo S, Okouchi K. Antigen of "serum sickness" type of heterophile antibodies in human sera: indentification as gangliosides with N-glycolylneuraminic acid. Biochem Biophys Res Commun 1977;79:388-395
-
(1977)
Biochem Biophys Res Commun
, vol.79
, pp. 388-395
-
-
Higashi, H.1
Naiki, M.2
Matuo, S.3
Okouchi, K.4
-
72
-
-
0032578387
-
A mutation in human CMP-sialic acid hydroxylase occurred after the Homo- Pan divergence
-
DOI 10.1073/pnas.95.20.11751
-
Chou HH, Takematsu H, Diaz S, et al. A mutation in human CMP-sialic acid hydroxylase occurred after the Homo-Pan divergence. Proc Natl Acad Sci USA 1998;95:11751-11756 • The genetic basis for the lack of a synthetic pathway for generation of Neu5Gc from Neu5Ac in humans was determined, which is one of only a few major genetic differences between humans and chimpanzees. (Pubitemid 28460486)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.20
, pp. 11751-11756
-
-
Chou, H.-H.1
Takematsu, H.2
Diaz, S.3
Iber, J.4
Nickerson, E.5
Wrights, K.L.6
Muchmore, E.A.7
Nelsons, D.L.8
Warren, S.T.9
Varki, A.10
-
73
-
-
57349192094
-
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
-
Byres E, Paton AW, Paton JC, et al. Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin. Nature 2008;456:648-652
-
(2008)
Nature
, vol.456
, pp. 648-652
-
-
Byres, E.1
Paton, A.W.2
Paton, J.C.3
|