Acute toxicity evaluation of in situ gel-forming controlled drug delivery system based on biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) copolymer

Biomedical Materials

Volumn 4, Issue 2, 2009, Pages

  Fang, Fang ^a   Gong, Chang Yang ^a,b   Dong, Peng Wei ^a   Fu, Shao Zhi ^a   Gu, Ying Chun ^a,b   Guo, Gang ^a   Zhao, Xia ^a   Wei, Yu Quan ^a   Qian, Zhi Yong ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CONTROLLED DRUG DELIVERY; COPOLYMERIZATION; DIMETHYL SULFOXIDE; ETHYLENE; ETHYLENE GLYCOL; FOURIER TRANSFORM INFRARED SPECTROSCOPY; GELATION; POLYETHYLENE OXIDES; TOXICITY;

ACUTE TOXICITY; ACUTE TOXICITY TEST; BALB/C MICE; BODY WEIGHT; CAPROLACTONE; CONTROLLED DRUG DELIVERY SYSTEMS; FTIR; HISTOPATHOLOGICAL EXAMINATIONS; IN-SITU; IN-SITU-GELLING; OBSERVATION PERIOD; TOXICITY TEST; TRIBLOCK COPOLYMERS;

POLYETHYLENE GLYCOLS;

COPOLYMER; DIMETHYL SULFOXIDE; MACROGOL; POLYCAPROLACTONE; POLYCAPROLACTONE POLY(ETHYLENE GLYCOL) POLYCAPROLACTONE COPOLYMER; UNCLASSIFIED DRUG; BIOMATERIAL; MACROGOL DERIVATIVE; POLY(EPSILON CAPROLACTONE) POLY(OXYETHYLENE) POLY(EPSILON CAPROLACTONE); POLY(EPSILON-CAPROLACTONE)-POLY(OXYETHYLENE)-POLY(EPSILON-CAPROLACTONE); POLYESTER; POLYMER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; EVALUATION; FEMALE; GEL; HEART; HISTOPATHOLOGY; INFRARED SPECTROSCOPY; INTESTINE; KIDNEY; LIVER; LUNG; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SPLEEN; STOMACH; SYNTHESIS; TOXICITY TESTING; ANIMAL; BAGG ALBINO MOUSE; BIODEGRADABLE IMPLANT; BODY WEIGHT; CHEMISTRY; GAS CHROMATOGRAPHY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TISSUE DISTRIBUTION;

MUS;

ABSORBABLE IMPLANTS; ANIMALS; BIOCOMPATIBLE MATERIALS; BODY WEIGHT; CHROMATOGRAPHY, GAS; DIMETHYL SULFOXIDE; DRUG DELIVERY SYSTEMS; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED BALB C; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMERS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TISSUE DISTRIBUTION;

EID: 67650649670     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/4/2/025002     Document Type: Article

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