Influence of heat treatment on spray-dried mixtures of Amioca® starch and Carbopol® 974P used as carriers for nasal drug delivery

International Journal of Pharmaceutics

Volumn 378, Issue 1-2, 2009, Pages 45-50

  Coucke, D ^a   Pringels, E ^a   Foreman, P ^b   Adriaensens, P ^c   Carleer, R ^c   Remon, J P ^a   Vervaet, C ^a  

^a GHENT UNIVERSITY   (Belgium)

^b NATIONAL STARCH AND CHEMICAL COMPANY   (United States)

^c HASSELT UNIVERSITY   (Belgium)

Author keywords

Amioca Carbopol 974P powder formulation; Heat treatment; Insulin; Nasal delivery; NMR spectroscopy

Indexed keywords

AMIOCA; CARBOMER; CARBOPOL 974P; METOPROLOL TARTRATE; NEUTRAL INSULIN; SALCATONIN; SOMATREM; STARCH; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; HEAT TREATMENT; MEAN RESIDENCE TIME; MUCOADHESION; MUCOCILIARY CLEARANCE; NONHUMAN; PRIORITY JOURNAL; RABBIT; VISCOELASTICITY; WATER ABSORPTION;

ACRYLATES; ADHESIVENESS; ADMINISTRATION, INTRANASAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CROSS-LINKING REAGENTS; DRUG CARRIERS; ELASTICITY; HOT TEMPERATURE; METOPROLOL; PEPTIDES; POWDERS; RABBITS; STARCH; VISCOSITY; ZEA MAYS;

EID: 67650635119     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2009.05.041     Document Type: Article

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