FANCJ helicase uniquely sense oxidative base damage in either strand of duplex DNA and is stimulated by replication protein A. to unwind the damaged DNA substrate in a strand-specific manner

Journal of Biological Chemistry

Volumn 284, Issue 27, 2009, Pages 18458-18470

  Suhasini, Avvaru N ^a   Sommers, Joshua A ^a   Mason, Aaron C ^b   Voloshin, Oleg N ^c   Camerini Otero, R Daniel ^c   Wold, Marc S ^b   Brosh Jr , Robert M ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8-OXOGUANINE; BIOCHEMICAL STUDIES; BREAST CANCER; CELLULAR PROCESS; COMPLEMENTATION; DNA HELICASES; DNA METABOLISM; DNA MOLECULES; DNA SUBSTRATES; DUPLEX DNA; FANCONI ANEMIAS; FUNCTIONAL INTERACTION; HELICASE; HELICASE ACTIVITIES; HELICASE SUBSTRATES; HIGH AFFINITY; MECHANISTIC STUDIES; OXIDATIVE BASE DAMAGE; RECQ HELICASES; REPLICATION PROTEIN A; REPLICATION PROTEINS; SINGLE-STRANDED DNA; SINGLE-STRANDED DNA-BINDING PROTEINS; TUMORIGENESIS;

BIOCHEMISTRY; DNA; ESCHERICHIA COLI; ETHYLENE GLYCOL; METABOLISM; NUCLEIC ACIDS; SUBSTRATES;

GENES;

8 HYDROXYGUANINE; DOUBLE STRANDED DNA; FANCJ HELICASE; GLYCOL; HELICASE; RECQ HELICASE; REPLICATION FACTOR A; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA DENATURATION; DNA METABOLISM; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; BREAST NEOPLASMS; DNA; DNA ADDUCTS; DNA DAMAGE; DNA HELICASES; ENZYME ACTIVATION; FANCONI ANEMIA; FANCONI ANEMIA COMPLEMENTATION GROUP PROTEINS; FEMALE; GUANINE; HUMANS; OXIDATIVE STRESS; REPLICATION PROTEIN A; SUBSTRATE SPECIFICITY; THYMINE;

ESCHERICHIA COLI;

EID: 67650563908     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.012229     Document Type: Article

References (48)

1. Levitus, M., Joenje, H., and de Winter, J. P. (2006) Cell Oncol. 28, 3-29
2. Taniguchi, T., and D'Andrea, A. D. (2006) Blood 107, 4223-4233
3. Wang, W. (2007) Nat. Rev. Genet. 8, 735-748
4. Levitus, M., Waisfisz, Q., Godthelp, B. C., de Vries, Y., Hussain, S., Wiegant, W. W., Elghalbzouri-Maghrani, E., Steltenpool, J., Rooimans, M. A., Pals, G., Arwert, F., Mathew, C. G., Zdzienicka, M. Z., Hiom, K., De Winter, J. P., and Joenje, H. (2005) Nat. Genet. 37, 934-935
5. Levran, O., Attwooll, C., Henry, R. T., Milton, K. L., Neveling, K., Rio, P., Batish, S. D., Kalb, R., Velleuer, E., Barral, S., Ott, J., Petrini, J., Schindler, D., Hanenberg, H., and Auerbach, A. D. (2005) Nat. Genet. 37, 931-933
6. Litman, R., Peng, M., Jin, Z., Zhang, F., Zhang, J., Powell, S., Andreassen, P. R., and Cantor, S. B. (2005) Cancer Cell 8, 255-265
7. Cantor, S. B., Bell, D. W., Ganesan, S., Kass, E. M., Drapkin, R., Grossman, S., Wahrer, D. C., Sgroi, D. C., Lane, W. S., Haber, D. A., and Livingston, D. M. (2001) Cell 105, 149-160
8. De Nicolo, A., Tancredi, M., Lombardi, G., Flemma, C. C., Barbuti, S., Di Cristofano, C., Sobhian, B., Bevilacqua, G., Drapkin, R., and Caligo, M. A. (2008) Clin. Cancer Res. 14, 4672-4680
9. Seal, S., Thompson, D., Renwick, A., Elliott, A., Kelly, P., Barfoot, R., Chagtai, T., Jayatilake, H., Ahmed, M., Spanova, K., North, B., McGuffog, L., Evans, D. G., Eccles, D., Easton, D. F., Stratton, M. R., and Rahman, N. (2006) Nat. Genet. 38, 1239-1241
10. Cantor, S., Drapkin, R., Zhang, F., Lin, Y., Han, J., Pamidi, S., and Livingston, D. M. (2004) Proc. Natl. Acad. Sci. U.S.A. 101, 2357-2362
11. Gupta, R., Sharma, S., Sommers, J. A., Jin, Z., Cantor, S. B., and Brosh, R. M., Jr. (2005) J. Biol. Chem. 280, 25450-25460
12. Peng, M., Litman, R., Jin, Z., Fong, G., and Cantor, S. B. (2006) Oncogene 25, 2245-2253
13. Bridge, W. L., Vandenberg, C. J., Franklin, R. J., and Hiom, K. (2005) Nat. Genet. 37, 953-957
14. Greenberg, R. A., Sobhian, B., Pathania, S., Cantor, S. B., Nakatani, Y., and Livingston, D. M. (2006) Genes Dev. 20, 34-46
15. Thompson, L. H., Hinz, J. M., Yamada, N. A., and Jones, N. J. (2005) Environ. Mol. Mutagen. 45, 128-142
16. Howlett, N. G., Taniguchi, T., Durkin, S. G., D'Andrea, A. D., and Glover, T. W. (2005) Hum. Mol. Genet. 14, 693-701
17. Wang, L. C., Stone, S., Hoatlin, M. E., and Gautier, J. (2008) DNA Repair 7, 1973-1981
18. Kumaraswamy, E., and Shiekhattar, R. (2007) Mol. Cell. Biol. 27, 6733-6741
19. Wu, Y., Shin-ya, K., and Brosh, R. M., Jr. (2008) Mol. Cell. Biol. 28, 4116-4128
20. Du, W., Adam, Z., Rani, R., Zhang, X., and Pang, Q. (2008) Antioxid. Redox. Signal. 10, 1909-1921
21. Wold, M. S. (1997) Annu. Rev. Biochem. 66, 61-92
22. Gupta, R., Sharma, S., Sommers, J. A., Kenny, M. K., Cantor, S. B., and Brosh, R. M., Jr. (2007) Blood 110, 2390-2398
23. Sharma, S., Sommers, J. A., Choudhary, S., Faulkner, J. K., Cui, S., Andreoli, L., Muzzolini, L., Vindigni, A., and Brosh, R. M., Jr. (2005) J. Biol. Chem. 280, 28072-28084
24. Sharma, S., Otterlei, M., Sommers, J. A., Driscoll, H. C., Dianov, G. L., Kao, H. I., Bambara, R. A., and Brosh, R. M., Jr. (2004) Mol. Biol. Cell 15, 734-750
25. Voloshin, O. N., and Camerini-Otero, R. D. (2007) J. Biol. Chem. 282, 18437-18447
26. Haring, S. J., Mason, A. C., Binz, S. K., and Wold, M. S. (2008) J. Biol. Chem. 283, 19095-19111
27. Lao, Y., Gomes, X. V., Ren, Y., Taylor, J. S., and Wold, M. S. (2000) Biochemistry 39, 850-859
28. Brosh, R. M., Jr., Waheed, J., and Sommers, J. A. (2002) J. Biol. Chem. 277, 23236-23245
29. Cadman, C. J., Matson, S. W., and McGlynn, P. (2006) J. Mol. Biol. 362, 18-25
30. Kaplan, D. L., and O'Donnell, M. (2002) Mol. Cell 10, 647-657
31. Gupta, R., Sharma, S., Doherty, K. M., Sommers, J. A., Cantor, S. B., and Brosh, R. M., Jr. (2006) Nucleic Acids Res. 34, 6673-6683
32. Voloshin, O. N., Vanevski, F., Khil, P. P., and Camerini-Otero, R. D. (2003) J. Biol. Chem. 278, 28284-28293
33. Rudolf, J., Makrantoni, V., Ingledew, W. J., Stark, M. J., and White, M. F. (2006) Mol. Cell 23, 801-808
34. Patel, S. S., and Picha, K. M. (2000) Annu. Rev. Biochem. 69, 651-697
35. Sharma, S., Doherty, K. M., and Brosh, R. M., Jr. (2006) Biochem. J. 398, 319-337
36. Sharma, S., and Brosh, R. M., Jr. (2008) Cell Cycle 7, 989-1000
37. Matson, S. W., Bean, D. W., and George, J. W. (1994) BioEssays 16, 13-22
38. Kim, C., Paulus, B. F., and Wold, M. S. (1994) Biochemistry 33, 14197-14206
39. Cui, S., Klima, R., Ochem, A., Arosio, D., Falaschi, A., and Vindigni, A. (2003) J. Biol. Chem. 278, 1424-1432
40. Kung, H. C., and Bolton, P. H. (1997) J. Biol. Chem. 272, 9227-9236
41. Wallace, S. S. (2002) Free Radic. Biol. Med. 33, 1-14
42. Brosh, R. M., Jr., and Matson, S. W. (1995) J. Bacteriol. 177, 5612-5621
43. Cui, S., Arosio, D., Doherty, K. M., Brosh, R. M., Jr., Falaschi, A., and Vindigni, A. (2004) Nucleic Acids Res. 32, 2158-2170
44. Brosh, R. M., Jr., Orren, D. K., Nehlin, J. O., Ravn, P. H., Kenny, M. K., Machwe, A., and Bohr, V. A. (1999) J. Biol. Chem. 274, 18341-18350
45. Brosh, R. M., Jr., Li, J. L., Kenny, M. K., Karow, J. K., Cooper, M. P., Kureekattil, R. P., Hickson, I. D., and Bohr, V. A. (2000) J. Biol. Chem. 275, 23500-23508
46. Patrick, S. M., and Turchi, J. J. (1999) J. Biol. Chem. 274, 14972-14978
47. Hazra, T. K., Das, A., Das, S., Choudhury, S., Kow, Y. W., and Roy, R. (2007) DNA Repair. 6, 470-480
48. Tornaletti, S., Maeda, L. S., Lloyd, D. R., Reines, D., and Hanawalt, P. C. (2001) J. Biol. Chem. 276, 45367-45371