Effects of streptozotocin-induced diabetes in domestic pigs with focus on the amino acid metabolism

Laboratory Animals

Volumn 43, Issue 3, 2009, Pages 249-254

  Jensen Waern, Marianne ^a   Andersson, M ^a   Kruse, R ^a   Nilsson, B ^b   Larsson, R ^b   Korsgren, O ^b   Essen Gustavsson B ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

Alanine; Branched chain amino acids; Hyperglycaemia; Muscle; Swine

Indexed keywords

AMINO ACID; C PEPTIDE; CARBOHYDRATE; GLUCOSE; STREPTOZOCIN; TAURINE;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DOMESTIC PIG; GLUCOSE BLOOD LEVEL; HYPERGLYCEMIA; HYPOGLYCEMIA; NONHUMAN; PANCREAS ISLET BETA CELL; STREPTOZOCIN DIABETES;

ALANINE; AMINO ACIDS; AMINO ACIDS, BRANCHED-CHAIN; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; C-PEPTIDE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; HYPERGLYCEMIA; INSULIN; MUSCLE, SKELETAL; SWINE; TAURINE;

ANIMALIA; SUIDAE; SUS SCROFA DOMESTICA;

EID: 67650561640     PISSN: 00236772     EISSN: None     Source Type: Journal    
DOI: 10.1258/la.2008.008069     Document Type: Article

References (33)

1. Buschard K, Thon R. Diabetic animal models. In: Hau J, Van Hoosier GL Jr, eds. Handbook of Laboratory Animal Science. Vol.II: Animal Models. MA, USA: CRC Press, 2003:153-182
2. Larsen MO, Rolin B. Use of the Göttingen minipig as a model of type 1 diabetes research, with special focus on type 1 diabetes research. ILAR J 2004;45:303-313
3. Gabel H, Bitter-Suermann H, Henriksson C, Save-Soderbergh J, Lundholm K, Brynger H. Streptozotocin diabetes in juvenile pigs. Evaluation of an experimental model. Horm Metab Res 1985;17:275-280
4. Lohr M, Lubbersmeyer J, Otremba B, Klapdor R, Grossner D, Kloppel G. Increase in B-cells in the pancreatic remnant after partial pancreatectomy in pigs. An immunocytochemical and functional study. Virchows Arch B Cell Pathol Incl Mol Pathol 1989;56:277-286
5. Marshall M, Sprandel U, Zöllner N. Streptozotocin diabetes in a miniature pig. Res Exp Med 1975;165:61-65
6. Taylor R, Agius L. The biochemistry of diabetes. Biochem J 1988;250:625-640
7. Rodríguez T, Alvarez B, Busquets S, Carbó N, López-Soriano FJ, Argilés JM. The increased skeletal muscle protein turnover of the streptozotocin diabetic rat is associated with high concentrations of branched-chain amino acids. Biochem Mol Med 1997;61:87-94 (Pubitemid 27291414)
8. Ross BD, Hems R, Krebs HA. The rate of gluconeogenesis from various precursors in the perfused rat liver. Biochem J 1967;102:942-951
9. Felig P, Pozefsky T, Marliss E, Cahill GF Jr. Alanine: key role in gluconeogenesis. Science 1970;167:1003-1004
10. Felig P, Wahren J, Sherwin R, Palaiologos G. Amino acid and protein metabolism in diabetes mellitus. Arch Int Med 1977;137:507-513 (Pubitemid 9009827)
11. Abu-Lebdeh HS, Barazzoni R, Meek SE, Bigelow ML, Persson XM, Nair KS. Effects of insulin deprivation and treatment on homocysteine metabolism in people with type 1 diabetes. J Clin Endocrinol Metab 2006;91:3344-3348 (Pubitemid 44402102)
12. Argilés JP, Costelli P, Carbo N, López-Soriano FJ. Branched-chain amino acid catabolism and cancer cachexia (review). Oncol Rep 1996;3:687-690 (Pubitemid 26201956)
13. Franconi F, Bennardini F, Mattana A, et al. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am J Clin Nutr 1995;61:1115-1119
14. De Luca G, Calpona PR, Caponetti A, et al. Taurine and osmoregulation: platelet taurine content, uptake, and release in type 2 diabetic patients. Metabolism 2001;50:60-64 (Pubitemid 32058550)
15. Tas S, Sarandol E, Ayvalik SZ, Serdar Z, Dirican M. Vanadyl sulfate, taurine, and combined vanadyl sulfate and taurine treatments in diabetic rats: effects on the oxidative and antioxidative systems. Arch Med Res 2007;38:276-283 (Pubitemid 46366080)
16. Wallgren P, Vallgårda J. SPF pigs - presentation, definition and specification of regulations. Swed Vet J 1993;45:733-735
17. Rodrigues H, Kunavongkrit A. Chronical venous catheterization for frequent blood sampling in unrestrained pigs. Acta Vet Scand 1983;24:318-320
18. Pfeifer R, Karol R, Korpi J, Burgoyne R, McCourt D. Practical application of HPLC to amino acid analysis. Am Lab 1983;15:77-84
19. Jonasson R, Essén-Gustavsson B, Jensen-Waern M. Blood concentrations of amino acids, glucose and lactate during experimental swine dysentery. Res Vet Sci 2007;82:323-331 (Pubitemid 46554811)
20. Brooke MH, Kaiser K. Muscle fibre types: how many and what kind? Arch Neurol 1970;23:369-379
21. Nair KS, Halliday D, Garrow JS. Increased energy expenditure in poorly controlled type 1 (insulin-dependent) diabetic patients. Diabetologia 1984;27:13-16 (Pubitemid 14096661)
22. Hara H, Lin YJ, Zhu X, et al. Safe induction of diabetes by high-dose streptozotocin in pigs. Pancreas 2008;36:31-38
23. Wahren J, Felig P, Cerasi E, Luft R. Splanchnic and peripheral glucose and amino acid metabolism in diabetes mellitus. J Clin Invest 1972;51:1870-1878
24. Flynn NE, Knabe DA, Mallick BK, Wu G. Postnatal changes of plasma amino acids in suckling pigs. J Anim Sci 2000;78:2369-2375
25. Blackshear PJ, Alberti KGMM. Sequential amino acid measurements during experimental diabetic ketoacidosis. Am J Physiol 1975;228:205-211
26. Wimhurst JM, Manchester KL. A comparison of the effects of diabetes induced with either alloxan or streptozotocin and of starvation on the activities in rat liver of the key enzymes of gluconeogenesis. Biochem J 1970;120:95-103
27. Kim SJ, Ramesh C, Gupta H, Lee W. Taurine-diabetes interaction: from involvement to protection. J Biol Regul Homeostat Agents 2007;21:63-77
28. Rudas B. Streptozotocin. Arzneimittel-Forschung 1972;22:830-861
29. Kröncke KD, Fehsel K, Sommer A, Rodriguez ML, Kolb-Bachofen V. Nitric oxide generation during cellular metabolization of the diabetogenic N-methyl-N-nitroso-urea streptozotozin contributes to islet cell DNA damage. Biol Chem Hoppe-Seyler 1995;376:179-185
30. Essén-Gustavsson B. Activity and inactivity related muscle adaption in the animal kingdom. In: Saltin B, ed. Biochemistry of Exercise, International Series on Sport Sciences, Vol.16. Champagne, IL: Human Kinetic Publishers, 1984:435-444
31. Essén-Gustavsson B, Borges O. Histochemical and metabolic characteristics of human skeletal muscle in relation to age. Acta Physiol Scand 1986;126:107-114 (Pubitemid 16061110)
32. Kiessling KH, Kiessling A. Fibre composition and enzyme activities in five different muscles from the Svalbard reindeer. Comp Biochem Physiol A Comp Physiol 1984;77:75-78
33. Essén B, Fohlin L, Thorén C, Saltin B. Skeletal muscle fibre types and sizes in anorexia nervosa patients. Clin Physiol 1981;4:395-403 (Pubitemid 12226110)