Kinetic, structural, and EPR studies reveal that aldehyde oxidoreductase from Desulfovibrio gigas does not need a sulfido ligand for catalysis and give evidence for a direct Mo-C interaction in a biological system

Journal of the American Chemical Society

Volumn 131, Issue 23, 2009, Pages 7990-7998

  Santos Silva, Teresa ^a   Ferroni, Felix ^b   Thapper, Anders ^a,c   Marangon, Jacopo ^a   González, Pablo J ^a   Rizzi, Alberto C ^b   Moura, Isabel ^a   Moura, José J G ^a   Romão, Maria J ^a   Brondino, Carlos D ^b  

^a UNIVERSIDADE NOVA DE LISBOA   (Portugal)

^b UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; BIOLOGICAL SYSTEMS; CATALYSIS; CRYSTAL ATOMIC STRUCTURE; CYANIDES; ETHYLENE; ETHYLENE GLYCOL; GLYCEROL; KINETICS; LIGANDS; MOLYBDENUM COMPOUNDS; POLYOLS; SINGLE CRYSTALS;

ALCOHOL MOIETIES; COORDINATION SPHERE; DIRECT INTERACTIONS; PYRAMIDAL COORDINATION; SQUARE-PYRAMIDAL GEOMETRY; STEADY-STATE KINETICS; STRUCTURAL EVIDENCE; XANTHINE OXIDASE;

ENZYME INHIBITION;

ALCOHOL; ALDEHYDE DEHYDROGENASE; ARSENIC TRIOXIDE; CARBOXYLIC ACID; CYANIDE; DITHIONITE; ETHYLENE GLYCOL; GLYCEROL; MOLYBDENUM; SULFIDE; WATER; CARBON; ENZYME INHIBITOR; LIGAND;

ARTICLE; ATOM; CHEMICAL BOND; CHEMICAL INTERACTION; CHEMICAL STRUCTURE; CRYSTAL; DESULFOVIBRIO GIGAS; ELECTRON SPIN RESONANCE; ENZYME ACTIVE SITE; ENZYME MECHANISM; GEOMETRY; OXIDATION; REACTION ANALYSIS; STEADY STATE; X RAY CRYSTALLOGRAPHY; CATALYSIS; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; PROTEIN CONFORMATION;

ALDEHYDE OXIDOREDUCTASES; CARBON; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYANIDES; DESULFOVIBRIO GIGAS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME INHIBITORS; ETHYLENE GLYCOL; GLYCEROL; LIGANDS; MOLYBDENUM; PROTEIN CONFORMATION;

EID: 67650531126     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja809448r     Document Type: Article

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