FMR1 premutation in females diagnosed with multiple sclerosis

Journal of Neurology, Neurosurgery and Psychiatry

Volumn 80, Issue 7, 2009, Pages 812-814

  Zhang, L ^a   Coffey, S ^b   Lua, L L ^a   Greco, C M ^a   Schafer, J A ^c   Brunberg, J ^a   Borodyanskaya, M ^b   Agius, M A ^a   Apperson, M ^a   Leehey, M ^d   Tartaglia, N ^b   Tassone, F ^b   Hagerman, P J ^a   Hagerman, R J ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Mercy Medical Group   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA1A INTERFERON; FRAGILE X MENTAL RETARDATION PROTEIN; GLATIRAMER; IMMUNOGLOBULIN G; METHYLPREDNISOLONE; PREDNISONE; STEROID;

ADULT; AMNESIA; ARM WEAKNESS; ATAXIA; BLADDER EMPTYING; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; COGNITIVE DEFECT; CONTRACTURE; DIFFUSION WEIGHTED IMAGING; DISEASE SEVERITY; DRUG DOSE REDUCTION; DRUG PULSE THERAPY; DYSARTHRIA; FATIGUE; FEMALE; FRAGILE X SYNDROME; GAIT DISORDER; GENE MUTATION; HUMAN; HYPERREFLEXIA; IMMUNOGLOBULIN BLOOD LEVEL; LEG DISEASE; LETTER; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PARESTHESIA; PERIPHERAL NEUROPATHY; PRIORITY JOURNAL; RANGE OF MOTION; SENSORY DYSFUNCTION; STEROID THERAPY; TREMOR; URINE INCONTINENCE; WEAKNESS;

BRAIN; COGNITION; FEMALE; FRAGILE X MENTAL RETARDATION PROTEIN; HETEROZYGOTE; HUMANS; MAGNETIC RESONANCE IMAGING; MIDDLE AGED; MULTIPLE SCLEROSIS; MUTATION; TREMOR; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 67650504640     PISSN: 00223050     EISSN: 1468330X     Source Type: Journal    
DOI: 10.1136/jnnp.2008.160960     Document Type: Letter

References (5)

1. Berry-Kravis E, Abrams L, Coffey SM, et al. Fragile X-associated tremor/ataxia syndrome: clinical features, genetics, and testing guidelines. Mov Disord 2007;22:2018-30.
2. Greco CM, Tassone F, Arocena DG, et al. Clinical and neuropathological findings in a woman with the FMR1 premutation and multiple sclerosis. Arch Neurol 2008;65:1114-16.
3. Poser CM, Brinar VV. Diagnostic criteria for multiple sclerosis. Clin Neurol Neurosurg 2001;103:1-11.
4. Adams JS, Adams PE, Nguyen D, et al. Volumetric brain changes in females with fragile X-associated tremor/ataxia syndrome (FXTAS). Neurology 2007;69:851-9.
5. Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol Sci 2001;22:117-39.