Lack of genetic association between the angiotensin-converting enzyme gene insertion/deletion polymorphism and longevity in a Han Chinese population

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 10, Issue 2, 2009, Pages 115-118

  Yang, Jian Kang ^a   Gong, Yuan Ying ^b   Xie, Liang ^b,c   Lian, Shi Gang ^d   Yang, Juan ^d   Xu, Liang You ^e   Gao, Shou Jun ^e   Zhang, Ya Ping ^a,b  

^a YUNNAN UNIVERSITY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^d People's Hospital of Dujiang Weirs City   (China)

^e Dujiangyan Longevity Research Centre   (China)

Author keywords

Angiotensin converting enzyme; Han Chinese population; Longevity; Polymorphism

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; CHINESE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HUMAN; LIFESPAN; LONGEVITY; MALE; POPULATION GENETICS; SEX DIFFERENCE;

AGED, 80 AND OVER; ASIAN CONTINENTAL ANCESTRY GROUP; CHINA; FEMALE; GENE DELETION; GENE FREQUENCY; HUMANS; LONGEVITY; MALE; MIDDLE AGED; MUTAGENESIS, INSERTIONAL; PEPTIDYL-DIPEPTIDASE A; POLYMORPHISM, GENETIC;

EID: 67650498885     PISSN: 14703203     EISSN: None     Source Type: Journal    
DOI: 10.1177/1470320309104873     Document Type: Article

References (22)

1. Terry DF, Evans JC, Pencina MJ et al. Characteristics of Framingham offspring participants with long-lived parents. Arch Intern Med 2007;167:438-44.
2. Herskind AM, McGue M., Holm NV, Sorensen TI, Harvald B., Vaupel JW The heritability of human longevity: A population-based study of 2872 Danish twin pairs born 1870-1900. Hum Genet 1996;97:319-23.
3. vB Hjelmborg J., Iachine I., Skytthe A. et al. Genetic influence on human lifespan and longevity. Hum Genet 2006;119:312-21.
4. Christensen K., Johnson TE, Vaupel JW The quest for genetic determinants of human longevity: Challenges and insights. Nat Rev Genet 2006;7:436-48.
5. Castellon R., Hamdi HK Demystifying the ACE polymorphism: From genetics to biology. Curr Pharm Des 2007;13:1191-8.
6. Panza F., D'Introno A., Capurso C. et al. Lipoproteins, vascular-related genetic factors, and human longevity. Rejuvenation Res 2007;10:441-58.
7. Schächter F., Faure-Delanef L., Guénot F. et al. Genetic associations with human longevity at the APOE and ACE loci. Nat Genet 1994;6:29-32.
8. Blanché H., Cabanne L., Sahbatou M., Thomas G. A study of French centenarians: Are ACE and APOE associated with longevity? C R Acad Sci III 2001;324:129-35.
9. Nacmias B., Bagnoli S., Tedde A. et al. Angiotensin converting enzyme insertion/deletion polymorphism in sporadic and familial Alzheimer's disease and longevity. Arch Gerontol Geriatr 2007;45:201-06.
10. Choi YH, Kim JH, Kim DK et al. Distributions of ACE and APOE polymorphisms and their relations with dementia status in Korean centenarians. J Gerontol A Biol Sci Med Sci 2003;58:227-31.
11. Seripa D., Franceschi M., Matera MG et al. Sex differences in the association of apolipoprotein E and angiotensin-converting enzyme gene polymorphisms with healthy aging and longevity: A population-based study from Southern Italy. J Gerontol A Biol Sci Med Sci 2006;61:918-23.
12. Rahmutula D., Nakayama T., Izumi Y. et al. Angiotensin-converting enzyme gene and longevity in the Xin Jiang Uighur autonomous region of China: an association study. J Gerontol A Biol Sci Med Sci 2002;57:M57-60.
13. Wufuer M., Fang MW, Cheng ZH, Qiu CC Polymorphism of angiotensin coverting enzyme gene and natural longevity in the Xinjiang Uygur people: An association study. Natl Med J China 2004;84:1603-06. (in Chinese)
14. Forero DA, Pinzón J., Arboleda GH et al. Analysis of common polymorphisms in angiotensin-converting enzyme and apolipoprotein E genes and human longevity in Colombia. Arch Med Res 2006;37:890-4.
15. Lindpaintner K., Pfeffer MA, Kreutz R. et al. A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med 1995;332:706-11.
16. Bladbjerg EM, Andersen-Ranberg K., de Maat MP et al. Longevity is independent of common variations in genes associated with cardiovascular risk. Thromb Haemost 1999;82:1100-05.
17. Panza F., Solfrizzi V., D'Introno A. et al. Angiotensin I converting enzyme (ACE) gene polymorphism in centenarians: Different allele frequencies between the North and South of Europe. Exp Gerontol 2003;38:1015-20.
18. Galinsky D., Tysoe C., Brayne CE et al. Analysis of the apo E/apo C-I, angiotensin converting enzyme and methylenetetrahydrofolate reductase genes as candidates affecting human longevity. Atherosclerosis 1997;129:177-83.
19. Hessner MJ, Dinauer DM, Kwiatkowski R., Neri B., Raife TJ Age-dependent prevalence of vascular disease-associated polymorphisms among 2689 volunteer blood donors. Clin Chem 2001;47:1879-84.
20. Yan CL, Zhan JB, Feng WB Gene polymorphisms of angiotensin II type 1 receptor and angiotensin-converting enzyme in two ethnic groups living in Zhejiang Province, China. J Renin Angiotensin Aldosterone Syst 2005;6:132-7.
21. Daimon M., Oizumi T., Saitoh T. et al. The D allele of the angiotension-converting enzyme insertion/deletion (I/D) polymorphism is a risk factor for type 2 diabetes in a population-based Japanese sample. Endocr J 2003;50:393-8.
22. Da Cruz IB, Oliveira G., Taufer M. et al. Angiotensin I-converting enzyme gene polymorphism in two ethnic groups living in Brazil's southern region: Association with age. J Gerontol A Biol Sci Med Sci 2003;58:851-6.