Ethanol inhibits L1 cell adhesion molecule tyrosine phosphorylation and dephosphorylation and activation of pp60src

Journal of Neurochemistry

Volumn 110, Issue 3, 2009, Pages 779-790

  Yeaney, Natalie K ^b   He, Min ^c   Tang, Ningfeng ^c   Malouf, Alfred T ^d   O'Riordan, Mary Ann ^e   Lemmon, Vance ^f   Bearer, Cynthia F ^a,c  

^a University of Maryland Hospital for Children   (United States)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^e NineSigma Inc   (United States)

^f UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Ethanol; Fetal alcohol syndrome; L1 cell adhesion molecule; Pp60 src; Tyrosine dephosphorylation; Tyrosine phosphorylation

Indexed keywords

ALCOHOL; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE CELL ADHESION MOLECULE L1; PROTEIN KINASE P60; TYROSINE;

ANIMAL TISSUE; ARTICLE; CEREBELLUM; CHICK EMBRYO; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; ENZYME INHIBITION; FETAL ALCOHOL SYNDROME; GRANULE CELL; GROWTH CONE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; SPINAL GANGLION;

ANIMALS; CELLS, CULTURED; CHICK EMBRYO; ETHANOL; MICE; NEURAL CELL ADHESION MOLECULE L1; ONCOGENE PROTEIN PP60(V-SRC); PHOSPHORYLATION; PROTEIN INTERACTION MAPPING; RATS; SIGNAL TRANSDUCTION; TYROSINE;

EID: 67650484201     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06143.x     Document Type: Article

References (47)

1. Alvestad R. M., Grosshans D. R., Coultrap S. J., Nakazawa T., Yamamoto T. Browning M. D. (2003) Tyrosine dephosphorylation and ethanol inhibition of N-Methyl-D-aspartate receptor function. J. Biol. Chem. 278, 11020 11025. (Pubitemid 36792651)
2. Bearer C. F. (2001) Mechanisms of brain injury: L1 cell adhesion molecule as a target for ethanol-induced prenatal brain injury. Semin. Pediatr. Neurol. 8, 100 107. (Pubitemid 32619723)
3. Bearer C. F., Swick A. R., O'Riordan M. A. Cheng G. (1999) Ethanol inhibits L1-mediated neurite outgrowth in postnatal rat cerebellar granule cells. J. Biol. Chem. 274, 13264 13270.
4. Bradley D. M., Paiva M., Tonjes L. A. Heaton M. B. (1995) In vitro comparison of the effects of ethanol and acetaldehyde on dorsal root ganglion neurons. Alcohol. Clin. Exp. Res. 19, 1345 1350.
5. Burden-Gulley S. M., Payne H. R. Lemmon V. (1995) Growth cones are actively influenced by substrate-bound adhesion molecules. J. Neurosci. 15, 4370 4381.
6. Charness M., Safran R. Perides G. (1994) Ethanol inhibits neural cell-cell adhesion. J. Biol. Chem. 269, 9304 9309. (Pubitemid 24209259)
7. Cheng L. Lemmon V. (2004) Pathological missense mutations of neural cell adhesion molecule L1 affect neurite outgrowth and branching on an L1 substrate. Mol. Cell. Neurosci. 27, 522 530. (Pubitemid 39540005)
8. Cheng L., Itoh K. Lemmon V. (2005) L1-mediated branching is regulated by two ezrin-radixin-moesin (ERM)-binding sites, the RSLE region and a novel juxtamembrane ERM-binding region. J. Neurosci. 25, 395 403. (Pubitemid 40105609)
9. Cohen N. R., Taylor J. S. H., Scott L. B., Guillery R. W., Soriano P. Furley A. J. W. (1997) Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1. Curr. Biol. 8, 26 33.
10. Craig A. M., Wyborski R. J. Banker G. (1995) Preferential addition of newly synthesized membrane protein at axonal growth cones. Nature 375, 592 594.
11. Dai Q., Zhang J. Pruett S. B. (2005) Ethanol alters cellular activation and CD14 partitioning in lipid rafts. Biochem. Biophys. Res. Commun. 332, 37 42. (Pubitemid 40719454)
12. Davis J. Q. Bennett V. (1994) Ankyrin binding activity shared by the neurofascin/L1/NrCAM family of nervous system cell adhesion molecules. J. Biol. Chem. 269, 27163 27166. (Pubitemid 24346527)
13. Deitrich R. A. Harris R. A. (1996) How much alcohol should I use in my experiments? Alcohol. Clin. Exp. Res. 20, 1 2. (Pubitemid 26074640)
14. Dolganiuc A., Bakis G., Kodys K., Mandrekar P. Szabo G. (2006) Acute ethanol treatment modulates Toll-like receptor-4 association with lipid rafts. Alcohol. Clin. Exp. Res. 30, 76 85. (Pubitemid 43341399)
15. Drazba J. Lemmon V. (1990) The role of cell adhesion molecules in neurite outgrowth on Muller cells. Dev. Biol. 138, 82 93.
16. Encinas M., Crowder R. J., Milbrandt J. Johnson E. M. Jr. (2004) Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival. J. Biol. Chem. 279, 18262 18269. (Pubitemid 38623240)
17. Ferrani-Kile K., Randall P. K. Leslie S. W. (2003) Acute ethanol affects phosphorylation state of the NMDA receptor complex: implication of tyrosine phosphatases and protein kinase A. Brain Res. Mol. Brain Res. 115, 78 86. (Pubitemid 36725038)
18. Fransen E., D'Hooge R., Van Camp G. et al. (1998) L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns. Hum. Mol. Genet. 7, 999 1009. (Pubitemid 28256593)
19. Garver T. D., Ren Q., Tuvia S. Bennett V. (1997) Tyrosine phosphorylation at a site highly conserved in the L1 family of cell adhesion molecules abolishes ankyrin binding and increases lateral mobility of neurofascin. J. Cell Biol. 137, 703 714. (Pubitemid 27200671)
20. Gil O. D., Sakurai T., Bradley A. E., Fink M. Y., Cassella M. R., Kuo J. A. Felsenfeld D. P. (2003) Ankyrin binding mediates L1CAM interactions with static components of the cytoskeleton and inhibits retrograde movement of L1CAM on the cell surface. J. Cell Biol. 162, 719 730. (Pubitemid 37022948)
21. Hallak H., Seiler A. E., Green J. S., Henderson A., Ross B. N. Rubin R. (2001) Inhibition of insulin-like growth factor-I signaling by ethanol in neuronal cells. Alcohol. Clin. Exp. Res. 25, 1058 1064. (Pubitemid 32656124)
22. Hamburger V. Hamilton H. L. (1951) A series of normal stages in the development of the chick embryo. J. Morphol. 88, 49 92.
23. Ignelzi M., Miller D., Soriano P. Maness P. (1994) Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1. Neuron 12, 873 884. (Pubitemid 24126247)
24. Kamiguchi H. Lemmon V. (1998) A neuronal form of the cell adhesion molecule L1 contains a tyrosine-based signal required for sorting to the axonal growth cone. J. Neurosci. 18, 3749 3756. (Pubitemid 28225682)
25. Kamiguchi H. Lemmon V. (2000) Recycling of the cell adhesion molecule L1 in axonal growth cones. J. Neurosci. 20, 3676 3686. (Pubitemid 30266230)
26. Kamiguchi H., Long K. E., Pendergast M., Schaefer A. W., Rapoport I., Kirchhausen T. Lemmon V. (1998) The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. J. Neurosci. 18, 5311 5321. (Pubitemid 28311948)
27. Lagenaur C. Lemmon V. (1987) An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension. Proc. Natl Acad. Sci. USA 84, 7753 7757.
28. Miura M., Kobayashi M., Asou H. Uyemura K. (1991) Molecular cloning of cDNA encoding the rat neural cell adhesion molecule L1. Two L1 isoforms in the cytoplasmic region are produced by differential splicing. FEBS Lett. 289, 91 95.
29. Moos M., Tacke R., Schere H., Teplow D., Fruh K. Schachner M. (1988) Neural adhesion molecule L1 as a member of the immunoglobulin superfamily with binding domains similar to fibronectin. Nature 334, 701 703. (Pubitemid 18197567)
30. Nakai Y. Kamiguchi H. (2002) Migration of nerve growth cones requires detergent-resistant membranes in a spatially defined and substrate-dependent manner. J. Cell Biol. 159, 1097 1108. (Pubitemid 36055763)
31. Nishio H. Suzuki K. (2002) Ethanol-induced Cas tyrosine phosphorylation and Fyn kinase activation in rat brain. Alcohol. Clin. Exp. Res. 26 (Suppl. 8 38S 43S. (Pubitemid 34913184)
32. Nishio H., Otsuka M., Kinoshita S., Tokuoka T., Nakajima M., Noda Y., Fukuyama Y. Suzuki K. (2002) Phosphorylation of c-Cbl protooncogene product following ethanol administration in rat cerebellum: possible involvement of Fyn kinase. Brain Res. 950, 203 209. (Pubitemid 35253931)
33. Roebuck T. M., Mattson S. N. Riley E. P. (1998) A review of the neuroanatomical findings in children with fetal alcohol syndrome. Alcohol. Clin. Exp. Res. 22, 339 344.
34. Schaefer A. W., Kamiguchi H., Wong E. V., Beach C. M., Landreth G. Lemmon V. (1999) Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization. J. Biol. Chem. 274, 37965 37967.
35. Schaefer A. W., Kamei Y., Kamiguchi H., Wong E. V., Rapoport I., Kirchhausen T., Beach C. M., Landreth G., Lemmon S. K. Lemmon V. (2002) L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1. J. Cell Biol. 157, 1223 1232. (Pubitemid 34847792)
36. Schmid R. S., Pruitt W. M. Maness P. F. (2000) A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis. J. Neurosci. 20, 4177 4188. (Pubitemid 30365688)
37. Sebastian B. M. Nagy L. E. (2005) Decreased insulin-dependent glucose transport by chronic ethanol feeding is associated with dysregulation of the Cbl/TC10 pathway in rat adipocytes. Am. J. Physiol. Endocrinol. Metab. 289, E1077 E1084.
38. Seiler A. E., Henderson A. Rubin R. (2000) Ethanol inhibits insulin receptor tyrosine kinase. Alcohol. Clin. Exp. Res. 24, 1869 1872. (Pubitemid 32001859)
39. Stratton K., Howe C. Battaglia F. (1996) Fetal Alcohol Syndrome: Diagnosis, Epidemiology, Prevention, and Treatment. National Academy Press, Washington, DC.
40. Suvarna N., Borgland S. L., Wang J., Phamluong K., Auberson Y. P., Bonci A. Ron D. (2005) Ethanol alters trafficking and functional N-methyl-D-aspartate receptor NR2 subunit ration via H-Ras. J. Biol. Chem. 36, 31450 31459. (Pubitemid 41291887)
41. Takeda Y., Asou H., Murakami Y., Miura M., Kobayashi M. Uyemura K. (1996) A nonneuronal isoform of cell adhesion molecule L1: tissue-specific expression and functional analysis. J. Neurochem. 66, 2338 2349. (Pubitemid 26159068)
42. Tang N., He M., O'Riordan M. A., Farkas C., Buck K., Lemmon L. Bearer C. F. (2006) Ethanol inhibits L1 cell adhesion molecule activation of mitogen-activated protein kinases. J. Neurochem. 96, 1480 1490.
43. Trowbridge I., Collawn J. Hopkins C. (1993) Signal-dependent membrane protein trafficking in the endocytic pathway. Annu. Rev. Cell Biol. 9, 129 161.
44. Watanabe H., Ymazaki M., Miyazaki H., Arikawa C., Itoh K., Sasaki T., Maehama T., Frohman M. A. Kanaho Y. (2004) Phospholipase D2 functions as a downstream signaling molecule of MAP kinase pathway in L1-stimulated neurite outgrowth of cerebellar granule neurons. J. Neurochem. 89, 142 151. (Pubitemid 38420683)
45. Wisco D., Anderson E. D., Chang M. C., Norden C., Boiko T., Folsch H. Winckler B. (2003) Uncovering multiple axonal targeting pathways in hippocampal neurons. J. Cell Biol. 162, 1317 1328. (Pubitemid 37210887)
46. Yaka R., Phamluong K. Ron D. (2003) Scaffolding of Fyn kinase to the NMDA receptor determines brain region sensitivity to ethanol. J. Neurosci. 23, 3623 3632. (Pubitemid 36958470)
47. Yip P. M., Zhao X., Montgomery A. M. Siu C. H. (1998) The Arg-Gly-Asp motif in the cell adhesion molecule L1 promotes neurite outgrowth via interaction with the. Mol. Cell. Biol. 9, 277 290.