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Volumn 66, Issue 7, 2009, Pages 756-763

N-acetylcysteine, a glutamate modulator, in the treatment of trichotillomania: A double-blind, placebo-controlled study

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; PLACEBO;

EID: 67650483697     PISSN: 0003990X     EISSN: 15383636     Source Type: Journal    
DOI: 10.1001/archgenpsychiatry.2009.60     Document Type: Article
Times cited : (341)

References (57)
  • 1
    • 0004235298 scopus 로고    scopus 로고
    • American Psychiatric Association, 4th Edition, Text Revision. Washington, DC: American Psychiatric Association;
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision. Washington, DC: American Psychiatric Association; 2000.
    • (2000) Diagnostic and Statistical Manual of Mental Disorders
  • 3
    • 33845997420 scopus 로고    scopus 로고
    • Trichotillomania Learning Center Scientific Advisory Board. The Trichotillomania Impact Project (TIP): Exploring phenomenology, functional impairment, and treatment utilization
    • Woods DW, Flessner CA, Franklin ME, Keuthen NJ, Goodwin RD, Stein DJ, Walther MR; Trichotillomania Learning Center Scientific Advisory Board. The Trichotillomania Impact Project (TIP): exploring phenomenology, functional impairment, and treatment utilization. J Clin Psychiatry. 2006;67(12):1877-1888.
    • (2006) J Clin Psychiatry , vol.67 , Issue.12 , pp. 1877-1888
    • Woods, D.W.1    Flessner, C.A.2    Franklin, M.E.3    Keuthen, N.J.4    Goodwin, R.D.5    Stein, D.J.6    Walther, M.R.7
  • 4
    • 0026088242 scopus 로고
    • Estimated lifetime prevalence of trichotillomania in college students
    • Christenson GA, Pyle RL, Mitchell JE. Estimated lifetime prevalence of trichotillomania in college students. J Clin Psychiatry. 1991;52(10):415-417.
    • (1991) J Clin Psychiatry , vol.52 , Issue.10 , pp. 415-417
    • Christenson, G.A.1    Pyle, R.L.2    Mitchell, J.E.3
  • 5
    • 67650390517 scopus 로고    scopus 로고
    • Odlaug BL, Grant JE. Prevalence of impulse control disorders in a college sample. In: New Research Program and Abstracts, 161st Annual Meeting of the American Psychiatric Association; May 3-8, 2008; Washington, DC. Abstract NR2-069.
    • Odlaug BL, Grant JE. Prevalence of impulse control disorders in a college sample. In: New Research Program and Abstracts, 161st Annual Meeting of the American Psychiatric Association; May 3-8, 2008; Washington, DC. Abstract NR2-069.
  • 6
    • 27744531192 scopus 로고    scopus 로고
    • Impulse control disorders in adult psychiatric inpatients
    • Grant JE, Levine L, Kim D, Potenza MN. Impulse control disorders in adult psychiatric inpatients. Am J Psychiatry. 2005;162(11):2184-2188.
    • (2005) Am J Psychiatry , vol.162 , Issue.11 , pp. 2184-2188
    • Grant, J.E.1    Levine, L.2    Kim, D.3    Potenza, M.N.4
  • 7
    • 10444265229 scopus 로고    scopus 로고
    • Impulsive disorders in Japanese adult patients with obsessive-compulsive disorder
    • Matsunaga H, Kiriike N, Matsui T, Oya K, Okino K, Stein DJ. Impulsive disorders in Japanese adult patients with obsessive-compulsive disorder. Compr Psychiatry. 2005;46(1):43-49.
    • (2005) Compr Psychiatry , vol.46 , Issue.1 , pp. 43-49
    • Matsunaga, H.1    Kiriike, N.2    Matsui, T.3    Oya, K.4    Okino, K.5    Stein, D.J.6
  • 8
    • 0001420562 scopus 로고
    • Alopicie par grattage (trichomanie ou trichotillomanie).
    • Hallopeau M. Alopicie par grattage (trichomanie ou trichotillomanie). Ann Dermatol Venereol. 1889;10:440-441.
    • (1889) Ann Dermatol Venereol , vol.10 , pp. 440-441
    • Hallopeau, M.1
  • 11
    • 0027191107 scopus 로고
    • Long-term treatment of trichotillomania (hair pulling)
    • Swedo SE, Lenane MC, Leonard HL. Long-term treatment of trichotillomania (hair pulling). N Engl J Med. 1993;329(2):141-142.
    • (1993) N Engl J Med , vol.329 , Issue.2 , pp. 141-142
    • Swedo, S.E.1    Lenane, M.C.2    Leonard, H.L.3
  • 15
    • 33646135776 scopus 로고    scopus 로고
    • Compulsive aspects of impulse-control disorders
    • Grant JE, Potenza MN. Compulsive aspects of impulse-control disorders. Psychiatr Clin North Am. 2006;29(2):539-551.
    • (2006) Psychiatr Clin North Am , vol.29 , Issue.2 , pp. 539-551
    • Grant, J.E.1    Potenza, M.N.2
  • 16
    • 0027090083 scopus 로고
    • Trichotillomania: An obsessive compulsive spectrum disorder?
    • Swedo SE, Leonard HL. Trichotillomania: an obsessive compulsive spectrum disorder? Psychiatr Clin North Am. 1992;15(4):777-790.
    • (1992) Psychiatr Clin North Am , vol.15 , Issue.4 , pp. 777-790
    • Swedo, S.E.1    Leonard, H.L.2
  • 17
    • 0028953375 scopus 로고
    • Trichotillomania and obsessive-compulsive disorder
    • discussion, 35
    • Stein DJ, Simeon D, Cohen LJ, Hollander E. Trichotillomania and obsessive-compulsive disorder. J Clin Psychiatry. 1995;56(suppl 4):28-34; discussion, 35.
    • (1995) J Clin Psychiatry , vol.56 , Issue.SUPPL. 4 , pp. 28-34
    • Stein, D.J.1    Simeon, D.2    Cohen, L.J.3    Hollander, E.4
  • 19
    • 34247170051 scopus 로고    scopus 로고
    • N-acetyl cysteine treatment of grooming disorders
    • Odlaug BL, Grant JE. N-acetyl cysteine treatment of grooming disorders. J Clin Psychopharmacol. 2007;27(2):227-229.
    • (2007) J Clin Psychopharmacol , vol.27 , Issue.2 , pp. 227-229
    • Odlaug, B.L.1    Grant, J.E.2
  • 20
    • 33846861283 scopus 로고    scopus 로고
    • Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania
    • Coric V, Kelmendi B, Pittenger C, Wasylink S, Bloch MH, Green J. Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with trichotillomania. J Clin Psychiatry. 2007;68(1):170-171.
    • (2007) J Clin Psychiatry , vol.68 , Issue.1 , pp. 170-171
    • Coric, V.1    Kelmendi, B.2    Pittenger, C.3    Wasylink, S.4    Bloch, M.H.5    Green, J.6
  • 21
    • 0037693859 scopus 로고    scopus 로고
    • Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior
    • McFarland K, Lapish CC, Kalivas PW. Prefrontal glutamate release into the core of the nucleus accumbens mediates cocaine-induced reinstatement of drug-seeking behavior. J Neurosci. 2003;23(8):3531-3537.
    • (2003) J Neurosci , vol.23 , Issue.8 , pp. 3531-3537
    • McFarland, K.1    Lapish, C.C.2    Kalivas, P.W.3
  • 24
    • 14644405541 scopus 로고    scopus 로고
    • Unmanageable motivation in addiction: A pathology in prefrontal-accumbens glutamate transmission
    • Kalivas PW, Volkow N, Seamans J. Unmanageable motivation in addiction: a pathology in prefrontal-accumbens glutamate transmission. Neuron. 2005;45(5):647-650.
    • (2005) Neuron , vol.45 , Issue.5 , pp. 647-650
    • Kalivas, P.W.1    Volkow, N.2    Seamans, J.3
  • 25
    • 17644374100 scopus 로고    scopus 로고
    • The neural basis of addiction: A pathology of motivation and choice
    • Kalivas PW, Volkow ND. The neural basis of addiction: a pathology of motivation and choice. Am J Psychiatry. 2005;162(8):1403-1413.
    • (2005) Am J Psychiatry , vol.162 , Issue.8 , pp. 1403-1413
    • Kalivas, P.W.1    Volkow, N.D.2
  • 27
    • 0028360019 scopus 로고
    • The assessment of trichotillomania
    • Rothbaum BO, Ninan PT. The assessment of trichotillomania. Behav Res Ther. 1994;32(6):651-662.
    • (1994) Behav Res Ther , vol.32 , Issue.6 , pp. 651-662
    • Rothbaum, B.O.1    Ninan, P.T.2
  • 28
    • 0002087481 scopus 로고    scopus 로고
    • Trichotillomania: Descriptive characteristics and phenomenology
    • Stein DJ, Christianson GA, Hollander E, eds, Washington, DC: American Psychiatric Press;
    • Christenson GA, Mansueto CS. Trichotillomania: descriptive characteristics and phenomenology. In: Stein DJ, Christianson GA, Hollander E, eds. Trichotillomania. Washington, DC: American Psychiatric Press; 1999:1-41.
    • (1999) Trichotillomania , pp. 1-41
    • Christenson, G.A.1    Mansueto, C.S.2
  • 29
    • 34548150512 scopus 로고    scopus 로고
    • N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: A pilot study
    • Grant JE, Kim SW, Odlaug BL. N-acetyl cysteine, a glutamate-modulating agent, in the treatment of pathological gambling: a pilot study. Biol Psychiatry. 2007;62(6):652-657.
    • (2007) Biol Psychiatry , vol.62 , Issue.6 , pp. 652-657
    • Grant, J.E.1    Kim, S.W.2    Odlaug, B.L.3
  • 31
    • 0034595823 scopus 로고    scopus 로고
    • Oral N-acetyl-cysteome increases the production of anti HIV chemokines in peripheral blood mononuclear cells
    • Cavallini L, Alexandre A. Oral N-acetyl-cysteome increases the production of anti HIV chemokines in peripheral blood mononuclear cells. Life Sci. 2000;67(2):147-154.
    • (2000) Life Sci , vol.67 , Issue.2 , pp. 147-154
    • Cavallini, L.1    Alexandre, A.2
  • 32
    • 67650390518 scopus 로고    scopus 로고
    • First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-Patient Edition SCID-I/P, Version 2.0, New York: Biometrics Research Department, New York State Psychiatric Institute; 1995
    • First MB, Spitzer RL, Gibbon M, Williams JBW. Structured Clinical Interview for DSM-IV-Patient Edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, New York State Psychiatric Institute; 1995.
  • 35
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol. 1959;32(1):50-55.
    • (1959) Br J Med Psychol , vol.32 , Issue.1 , pp. 50-55
    • Hamilton, M.1
  • 38
    • 0002302592 scopus 로고
    • Clinical validation of the Quality of Life Inventory: A measure of life satisfaction for use in treatment planning and outcome assessment
    • Frisch MB, Cornell J, Villaneuva M. Clinical validation of the Quality of Life Inventory: a measure of life satisfaction for use in treatment planning and outcome assessment. Psychol Assess. 1993;4(1):92-101.
    • (1993) Psychol Assess , vol.4 , Issue.1 , pp. 92-101
    • Frisch, M.B.1    Cornell, J.2    Villaneuva, M.3
  • 40
    • 34249317588 scopus 로고    scopus 로고
    • Trichotillomania Learning Center Scientific Advisory Board. Factor analysis of the Massachusetts General Hospital Hairpulling Scale
    • Keuthen NJ, Flessner CA, Woods DW, Franklin ME, Stein DJ, Cashin SE; Trichotillomania Learning Center Scientific Advisory Board. Factor analysis of the Massachusetts General Hospital Hairpulling Scale. J Psychosom Res. 2007;62(6):707-709.
    • (2007) J Psychosom Res , vol.62 , Issue.6 , pp. 707-709
    • Keuthen, N.J.1    Flessner, C.A.2    Woods, D.W.3    Franklin, M.E.4    Stein, D.J.5    Cashin, S.E.6
  • 41
    • 0005698493 scopus 로고    scopus 로고
    • Trichotillomania and obsessive-compulsive disorder
    • Stein DJ, Christianson GA, Hollander E, eds, Washington, DC: American Psychiatric Press;
    • Stanley MA, Cohen LJ. Trichotillomania and obsessive-compulsive disorder. In: Stein DJ, Christianson GA, Hollander E, eds. Trichotillomania. Washington, DC: American Psychiatric Press; 1999:225-261.
    • (1999) Trichotillomania , pp. 225-261
    • Stanley, M.A.1    Cohen, L.J.2
  • 44
    • 0003412410 scopus 로고
    • Rockville, MD: National Institute of Mental Health;, Publication (ADM) 76-338
    • Guy W. ECDEU Assessment Manual for Psychopharmacology. Rockville, MD: National Institute of Mental Health; 1976. Publication (ADM) 76-338.
    • (1976) ECDEU Assessment Manual for Psychopharmacology
    • Guy, W.1
  • 45
    • 0026081811 scopus 로고
    • Clinical significance: A statistical approach to defining meaningful change in psychotherapy research
    • Jacobson NS, Truax P. Clinical significance: a statistical approach to defining meaningful change in psychotherapy research. J Consult Clin Psychol. 1991;59(1):12-19.
    • (1991) J Consult Clin Psychol , vol.59 , Issue.1 , pp. 12-19
    • Jacobson, N.S.1    Truax, P.2
  • 46
    • 33747182508 scopus 로고    scopus 로고
    • Single modality versus dual modality treatment for trichotillomania: Sertraline, behavioral therapy, or both?
    • Dougherty DD, Loh R, Jenike MA, Keuthen NJ. Single modality versus dual modality treatment for trichotillomania: sertraline, behavioral therapy, or both? J Clin Psychiatry. 2006;67(7):1086-1092.
    • (2006) J Clin Psychiatry , vol.67 , Issue.7 , pp. 1086-1092
    • Dougherty, D.D.1    Loh, R.2    Jenike, M.A.3    Keuthen, N.J.4
  • 48
    • 0037629080 scopus 로고    scopus 로고
    • Treatment of trichotillomania with behavioral therapy or fluoxetine: A randomized, waiting-list controlled study
    • van Minnen A, Hoogduin KA, Keijsers GP, Hellenbrand I, Hendriks GJ. Treatment of trichotillomania with behavioral therapy or fluoxetine: a randomized, waiting-list controlled study. Arch Gen Psychiatry. 2003;60(5):517-522.
    • (2003) Arch Gen Psychiatry , vol.60 , Issue.5 , pp. 517-522
    • van Minnen, A.1    Hoogduin, K.A.2    Keijsers, G.P.3    Hellenbrand, I.4    Hendriks, G.J.5
  • 49
    • 33644999721 scopus 로고    scopus 로고
    • A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania
    • Woods DW, Wetterneck CT, Flessner CA. A controlled evaluation of acceptance and commitment therapy plus habit reversal for trichotillomania. Behav Res Ther. 2006;44(5):639-656.
    • (2006) Behav Res Ther , vol.44 , Issue.5 , pp. 639-656
    • Woods, D.W.1    Wetterneck, C.T.2    Flessner, C.A.3
  • 51
    • 0028169881 scopus 로고
    • N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro
    • Mayer M, Noble M. N-acetyl-L-cysteine is a pluripotent protector against cell death and enhancer of trophic factor-mediated cell survival in vitro. Proc Natl Acad Sci U S A. 1994;91(16):7496-7500.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , Issue.16 , pp. 7496-7500
    • Mayer, M.1    Noble, M.2
  • 52
    • 1642462339 scopus 로고    scopus 로고
    • Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of n-acetyl- cysteine after nerve injury
    • Hart AM, Terenghi G, Kellerth JO, Wiberg M. Sensory neuroprotection, mitochondrial preservation, and therapeutic potential of n-acetyl- cysteine after nerve injury. Neuroscience. 2004;125(1):91-101.
    • (2004) Neuroscience , vol.125 , Issue.1 , pp. 91-101
    • Hart, A.M.1    Terenghi, G.2    Kellerth, J.O.3    Wiberg, M.4
  • 53
    • 0030707678 scopus 로고    scopus 로고
    • Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants
    • Han D, Sen CK, Roy S, Kobayashi MS, Tritschler HJ, Packer L. Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants. Am J Physiol. 1997;273(5, pt 2):R1771-R1778.
    • (1997) Am J Physiol , vol.273 , Issue.5 and PART 2
    • Han, D.1    Sen, C.K.2    Roy, S.3    Kobayashi, M.S.4    Tritschler, H.J.5    Packer, L.6
  • 55
    • 40149097728 scopus 로고    scopus 로고
    • Styles of pulling in trichotillomania: Exploring differences in symptom severity, phenomenology, and functional impact
    • Flessner CA, Conelea CA, Woods DW, Franklin ME, Keuthen NJ, Cashin SE. Styles of pulling in trichotillomania: exploring differences in symptom severity, phenomenology, and functional impact. Behav Res Ther. 2008;46(3):345-357.
    • (2008) Behav Res Ther , vol.46 , Issue.3 , pp. 345-357
    • Flessner, C.A.1    Conelea, C.A.2    Woods, D.W.3    Franklin, M.E.4    Keuthen, N.J.5    Cashin, S.E.6
  • 56
    • 48249115593 scopus 로고    scopus 로고
    • Acceptance-enhanced behavior therapy (AEBT) for trichotillomania and chronic skin picking: Exploring the effects of component sequencing
    • Flessner CA, Busch AM, Heideman PW, Woods DW. Acceptance-enhanced behavior therapy (AEBT) for trichotillomania and chronic skin picking: exploring the effects of component sequencing. Behav Modif. 2008;32(5):579-594.
    • (2008) Behav Modif , vol.32 , Issue.5 , pp. 579-594
    • Flessner, C.A.1    Busch, A.M.2    Heideman, P.W.3    Woods, D.W.4
  • 57
    • 33750354500 scopus 로고    scopus 로고
    • Group treatment for trichotillomania: Behavior therapy versus supportive therapy
    • Diefenbach GJ, Tolin DF, Hannan S, Maltby N, Crocetto J. Group treatment for trichotillomania: behavior therapy versus supportive therapy. Behav Ther. 2006;37(4):353-363.
    • (2006) Behav Ther , vol.37 , Issue.4 , pp. 353-363
    • Diefenbach, G.J.1    Tolin, D.F.2    Hannan, S.3    Maltby, N.4    Crocetto, J.5


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