Hepatocyte growth factor activator is a serum activator of single-chain precursor macrophage-stimulating protein

FEBS Journal

Volumn 276, Issue 13, 2009, Pages 3481-3490

  Kawaguchi, Makiko ^a   Orikawa, Hiroshi ^a   Baba, Takashi ^a   Fukushima, Tsuyoshi ^a   Kataoka, Hiroaki ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

Activation; Hepatocyte growth factor activator; Macrophage stimulating protein; Recepteur d'origine nantais (RON); Serum

Indexed keywords

BLOOD CLOTTING FACTOR 11A; HEPATOCYTE GROWTH FACTOR ACTIVATOR; IMMUNOGLOBULIN G ANTIBODY; MACROPHAGE ACTIVATING FACTOR; PROTEINASE; SCATTER FACTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD SAMPLING; CELL INFILTRATION; CONTROLLED STUDY; IN VITRO STUDY; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKIN INJURY; WILD TYPE;

ANIMALS; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; ENZYME ACTIVATION; HEPATOCYTE GROWTH FACTOR; HUMANS; KALLIKREINS; MACROPHAGES, PERITONEAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; PROTEIN PRECURSORS; PROTO-ONCOGENE PROTEINS; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; SERUM;

MUS;

EID: 67650472211     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07070.x     Document Type: Article

References (32)

1. Skeel A, Yoshimura T, Showalter SD, Tanaka S, Appella E Leonard EJ (1991) Macrophage stimulating protein: purification, partial amino acid sequence, and cellular activity. J Exp Med 173, 1227 1234.
2. Yoshimura T, Yuhki N, Wang MH, Skeel A Leonard EJ (1993) Cloning, sequencing, and expression of human macrophage stimulating protein (MSP, MST1) confirms MSP as a member of the family of kringle proteins and locates the MSP gene on chromosome 3. J Biol Chem 268, 15461 15468.
3. Shimamoto A, Kimura T, Matsumoto K Nakamura T (1993) Hepatocyte growth factor-like protein is identical to macrophage stimulating protein. FEBS Lett 333, 61 66.
4. Wang MH, Ronsin C, Gesnel MC, Coupey L, Skeel A, Leonard EJ Breathnach R (1994) Identification of the ron gene product as the receptor for the human macrophage stimulating protein. Science 266, 117 119. (Pubitemid 24345331)
5. Wang MH, Zhou YQ Chen YQ (2002) Macrophage-stimulating protein and RON receptor tyrosine kinase: potential regulators of macrophage inflammatory activities. Scand J Immunol 56, 545 553.
6. Bezerra JA, Witte DP, Aronow BJ Degen SJ (1993) Hepatocyte-specific expression of the mouse hepatocyte growth factor-like protein. Hepatology 18, 394 399. (Pubitemid 23225112)
7. Wang MH, Yoshimura T, Skeel A Leonard EJ (1994) Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade. J Biol Chem 269, 3436 3440. (Pubitemid 24237662)
8. Wang MH, Skeel A Leonard EJ (1996) Proteolytic cleavage and activation of pro-macrophage-stimulating protein by resident peritoneal macrophage membrane proteases. J Clin Invest 97, 720 727. (Pubitemid 26057091)
9. Bhatt AS, Welm A, Farady CJ, Vásquez M, Wilson K Craik CS (2007) Coordinate expression and functional profiling identify an extracellular proteolytic signaling pathway. Proc Natl Acad Sci USA 104, 5771 5776. (Pubitemid 47175609)
10. Wang MH, Gonias SL, Skeel A, Wolf BB, Yoshimura T Leonard EJ (1994) Proteolytic activation of single-chain precursor macrophage-stimulating protein by nerve growth factor-gamma and epidermal growth factor-binding protein, members of the kallikrein family. J Biol Chem 269, 13806 13810. (Pubitemid 24191124)
11. Benvenuti S Comoglio PM (2007) The MET receptor tyrosine kinase in invasion and metastasis. J Cell Physiol 213, 316 325. (Pubitemid 47509708)
12. Kataoka H, Miyata S, Uchinokura S Itoh H (2003) Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factor. Cancer Metastasis Rev 22, 223 236. (Pubitemid 36561059)
13. Miyazawa K, Shimomura T, Kitamura A, Kondo J, Morimoto Y Kitamura N (1993) Molecular cloning and sequence analysis of the cDNA for a human serine protease responsible for activation of hepatocyte growth factor. Structural similarity of the protease precursor to blood coagulation factor XII. J Biol Chem 268, 10024 10028.
14. Hayashi T, Nishioka J, Nakagawa N, Kamada H, Gabazza EC, Kobayashi T, Hattori A Suzuki K (2007) Proteinb C inhibitor directly and potently inhibits activated hepatocyte growth factor activator. J Thromb Haemost 5, 1477 1485. (Pubitemid 46965378)
15. Miyazawa K, Shimomura T Kitamura N (1996) Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator. J Biol Chem 271, 3615 3618. (Pubitemid 26065675)
16. Shimomura T, Kondo J, Ochiai M, Naka D, Miyazawa K, Morimoto Y Kitamura N (1993) Activation of the zymogen of hepatocyte growth factor activator by thrombin. J Biol Chem 268, 22927 22932.
17. Mukai S, Fukushima T, Naka D, Tanaka H, Osada Y Kataoka H (2008) Activation of hepatocyte growth factor activator zymogen (pro-HGFA) by human kallikrein 1-related peptidases. FEBS J 275, 1003 1017. (Pubitemid 351230213)
18. Itoh H, Naganuma S, Takeda N, Miyata S, Uchinokura S, Fukushima T, Uchiyama S, Tanaka H, Nagaike K, Shimomura T et al. (2004) Regeneration of injured intestinal mucosa is impaired in hepatocyte growth factor activator-deficient mice. Gastroenterology 127, 1423 1435. (Pubitemid 39457769)
19. Kataoka H, Shimomura T, Kawaguchi T, Hamasuna R, Itoh H, Kitamura N, Miyazawa K Koono M (2000) Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment. J Biol Chem 275, 40453 40462. (Pubitemid 32064680)
20. Okino T, Egami H, Ohmachi H, Takai E, Tamori Y, Nakagawa A, Nakano S, Sakamoto O, Suda T Ogawa M (1991) Immunohistochemical analysis of distribution of RON receptor tyrosine kinase in human digestive organs. Dig Dis Sci 46, 424 429.
21. Wang MH, Lee W, Luo YL, Weis MT Yao HP (2007) Altered expression of the RON receptor tyrosine kinase in various epithelial cancers and its contribution to tumorigenic phenotypes in thyroid cancer cells. J Pathol 213, 402 411. (Pubitemid 350206512)
22. Correll PH, Iwama A, Tondat S, Mayrhofer G, Suda T Bernstein A (1997) Deregulated inflammatory response in mice lacking the STK/RON receptor tyrosine kinase. Genes Funct 1, 69 83.
23. Muraoka RS, Sun WY, Colbert MC, Waltz SE, Witte DP, Degen JL Friezner Degen SJ (1999) The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse. J Clin Invest 103, 1277 1285. (Pubitemid 29218298)
24. Morrison AC, Wilson CB, Ray M Correll PH (2004) Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide. J Immunol 172, 1825 1832. (Pubitemid 38116831)
25. Danilkovitch-Miagkova A Leonard EJ (2001) Anti-apoptotic action of macrophage stimulating protein (MSP). Apoptosis 6, 183 190. (Pubitemid 32423727)
26. Cantaluppi V, Biancone L, Romanazzi GM, Figliolini F, Beltramo S, Galimi F, Camboni MG, Deriu E, Conaldi P, Bottelli A et al. (2008) Macrophage stimulating protein may promote tubular regeneration after acute injury. J Am Soc Nephrol 19, 1904 1918.
27. O'Toole JM, Rabenau KE, Burns K, Lu D, Mangalampalli V, Balderes P, Covino N, Bassi R, Prewett M, Gottfredsen KJ et al. (2006) Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member. Cancer Res 66, 9162 9170. (Pubitemid 44521136)
28. Welm AL, Sneddon JB, Taylor C, Nuyten DS, van de Vijver MJ, Hasegawa BH Bishop JM (2007) The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans. Proc Natl Acad Sci USA 104, 7570 7575. (Pubitemid 47185947)
29. Lee SL, Dickson RB Lin CY (2000) Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease. J Biol Chem 275, 36720 36725. (Pubitemid 32002078)
30. Suzuki K (2008) The multi-functional serpin, protein C inhibitor: beyond thrombosis and hemostasis. J Thromb Haemost 6, 2017 2026.
31. Kataoka H, Hamasuna R, Itoh H, Kitamura N Koono M (2000) Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma. Cancer Res 60, 6148 6159. (Pubitemid 30839648)
32. Suzuki Y, Funakoshi H, Machide M, Matsumoto K Nakamura T (2008) Regulation of cell migration and cytokine production by HGF-like protein (HLP)/macrophage stimulating protein (MSP) in primary microglia. Biomed Res 29, 77 84. (Pubitemid 351753466)