메뉴 건너뛰기




Volumn 37, Issue 5, 2009, Pages 1823-1824

Thrombin-activatable fibrinolysis inhibitor-a inhibitors: Drugs for sepsis or drugs for disseminated intravascular coagulation?

Author keywords

Disseminated intravascular coagulation; Sepsis; TAFIa; Thrombin

Indexed keywords

ANTIFIBRINOLYTIC AGENT; ANTITHROMBIN; D DIMER; FIBRIN; FIBRINOGEN; PLASMIN; PLASMINOGEN ACTIVATOR INHIBITOR; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR; THROMBIN ACTIVATABLE FIBRINOLYSIS INHIBITOR A INHIBITOR; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

EID: 67650470173     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181a09708     Document Type: Editorial
Times cited : (1)

References (28)
  • 1
    • 67650470216 scopus 로고    scopus 로고
    • EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats
    • Muto Y, Suzuki K, Iida H, et al: EF6265, a novel inhibitor of activated thrombin-activatable fibrinolysis inhibitor, protects against sepsis-induced organ dysfunction in rats. Crit Care Med 2009; 37:1744-1749
    • (2009) Crit Care Med , vol.37 , pp. 1744-1749
    • Muto, Y.1    Suzuki, K.2    Iida, H.3
  • 2
    • 0029044322 scopus 로고
    • Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor
    • Bajzar L, Manuel R, Nesheim ME: Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor. J Biol Chem 1995; 270:14477-14484
    • (1995) J Biol Chem , vol.270 , pp. 14477-14484
    • Bajzar, L.1    Manuel, R.2    Nesheim, M.E.3
  • 3
    • 0032538557 scopus 로고    scopus 로고
    • A study of the mechanism of inhibition of fibrino-lysis by activated thrombin-activable fibri-nolysis inhibitor
    • Wang W, Boffa MB, Bajzar L, et al: A study of the mechanism of inhibition of fibrino-lysis by activated thrombin-activable fibri-nolysis inhibitor. J Biol Chem 1998; 273: 27176-27181
    • (1998) J Biol Chem , vol.273 , pp. 27176-27181
    • Wang, W.1    Boffa, M.B.2    Bajzar, L.3
  • 4
    • 1842728323 scopus 로고    scopus 로고
    • Activated thrombin-activatable fibrinolysis inhibitor reduces the ability of high molecular weight fibrin degradation products to protect plasmin from antiplasmin
    • Schneider M, Brufatto N, Neill E, et al: Activated thrombin-activatable fibrinolysis inhibitor reduces the ability of high molecular weight fibrin degradation products to protect plasmin from antiplasmin. J Biol Chem 2004; 279:13340-13345
    • (2004) J Biol Chem , vol.279 , pp. 13340-13345
    • Schneider, M.1    Brufatto, N.2    Neill, E.3
  • 5
    • 0017254377 scopus 로고
    • Globular hyaline microthrombi - Their nature and morphogenesis
    • Bleyl U, Rossner JA: Globular hyaline microthrombi - Their nature and morphogenesis. Virchows Arch A Pathol Anat Histol 1976; 370: 113-128
    • (1976) Virchows Arch A Pathol Anat Histol , vol.370 , pp. 113-128
    • Bleyl, U.1    Rossner, J.A.2
  • 6
    • 0035160476 scopus 로고    scopus 로고
    • Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation
    • Taylor FB Jr, Toh CH, Hoots WK, et al: Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost 2001; 86:1327-1330
    • (2001) Thromb Haemost , vol.86 , pp. 1327-1330
    • Taylor Jr, F.B.1    Toh, C.H.2    Hoots, W.K.3
  • 7
    • 0042925576 scopus 로고    scopus 로고
    • Comparison of diagnostic criteria for disseminated intravascular coagulation (DIC): Diagnostic criteria of the International Society of Thrombosis and Hemostasis and of the Japanese Ministry of Health and Welfare for overt DIC
    • Wada H, Gabazza EC, Asakura H, et al: Comparison of diagnostic criteria for disseminated intravascular coagulation (DIC): Diagnostic criteria of the International Society of Thrombosis and Hemostasis and of the Japanese Ministry of Health and Welfare for overt DIC. Am J Hematol 2003; 74:17-22
    • (2003) Am J Hematol , vol.74 , pp. 17-22
    • Wada, H.1    Gabazza, E.C.2    Asakura, H.3
  • 8
    • 19944434119 scopus 로고    scopus 로고
    • Evaluation of new Japanese diagnostic criteria for disseminated intravascular coagulation in critically ill patients
    • Gando S, Wada H, Asakura H, et al: Evaluation of new Japanese diagnostic criteria for disseminated intravascular coagulation in critically ill patients. Clin Appl Thromb Hemost 2005; 11:71-76
    • (2005) Clin Appl Thromb Hemost , vol.11 , pp. 71-76
    • Gando, S.1    Wada, H.2    Asakura, H.3
  • 9
    • 1842547895 scopus 로고    scopus 로고
    • Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation
    • Dhainaut JF, Yan SB, Joyce DE, et al: Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation. J Thromb Haemost 2004; 2:1924-1933
    • (2004) J Thromb Haemost , vol.2 , pp. 1924-1933
    • Dhainaut, J.F.1    Yan, S.B.2    Joyce, D.E.3
  • 10
    • 10644283860 scopus 로고    scopus 로고
    • Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravas-cular coagulation
    • Bakhtiari K, Meijers JC, de Jonge E, et al: Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravas-cular coagulation. Crit Care Med 2004; 32: 2416-2421
    • (2004) Crit Care Med , vol.32 , pp. 2416-2421
    • Bakhtiari, K.1    Meijers, J.C.2    de Jonge, E.3
  • 11
    • 25144505780 scopus 로고    scopus 로고
    • Modified score for disseminated intravascular coagulation in the critically ill
    • Sivula M, Tallgren M, Pettila V: Modified score for disseminated intravascular coagulation in the critically ill. Intensive Care Med 2005; 31:1209-1214
    • (2005) Intensive Care Med , vol.31 , pp. 1209-1214
    • Sivula, M.1    Tallgren, M.2    Pettila, V.3
  • 12
    • 1842788553 scopus 로고    scopus 로고
    • Use of soluble fibrin antigen instead of D-dimer as fibrin-related marker may enhance the prognostic power of the ISTH overt DIC score
    • Dempfle CE, Wurst M, Smolinski M, et al: Use of soluble fibrin antigen instead of D-dimer as fibrin-related marker may enhance the prognostic power of the ISTH overt DIC score. Thromb Haemost 2004; 91:812-818
    • (2004) Thromb Haemost , vol.91 , pp. 812-818
    • Dempfle, C.E.1    Wurst, M.2    Smolinski, M.3
  • 13
    • 31344446122 scopus 로고    scopus 로고
    • New disseminated intravascular coagulation score: A useful tool to predict mortality in comparison with Acute Physiology and Chronic Health Evaluation II and Logistic Organ Dysfunction scores
    • quiz 328
    • Angstwurm MW, Dempfle CE, Spannagl M: New disseminated intravascular coagulation score: A useful tool to predict mortality in comparison with Acute Physiology and Chronic Health Evaluation II and Logistic Organ Dysfunction scores. Crit Care Med 2006; 34:314 -320; quiz 328
    • (2006) Crit Care Med , vol.34 , pp. 314-320
    • Angstwurm, M.W.1    Dempfle, C.E.2    Spannagl, M.3
  • 14
    • 0035341175 scopus 로고    scopus 로고
    • Protein C replacement in severe meningococcemia: Rationale and clinical experience
    • Alberio L, Lammle B, Esmon CT: Protein C replacement in severe meningococcemia: Rationale and clinical experience. Clin Infect Dis 2001; 32:1338-1346
    • (2001) Clin Infect Dis , vol.32 , pp. 1338-1346
    • Alberio, L.1    Lammle, B.2    Esmon, C.T.3
  • 15
    • 0037271391 scopus 로고    scopus 로고
    • Acute infectious purpura fulminans: A 15-year retrospective review of 28 consecutive cases
    • Childers BJ, Cobanov B: Acute infectious purpura fulminans: A 15-year retrospective review of 28 consecutive cases. Am Surg 2003; 69:86-90
    • (2003) Am Surg , vol.69 , pp. 86-90
    • Childers, B.J.1    Cobanov, B.2
  • 16
    • 0030044808 scopus 로고    scopus 로고
    • Purpura fulminans in severe congenital protein C deficiency: Monitoring of treatment with protein C concentrate
    • Muller FM, Ehrenthal W, Hafner G, et al: Purpura fulminans in severe congenital protein C deficiency: Monitoring of treatment with protein C concentrate. Eur J Pediatr 1996; 155:20-25
    • (1996) Eur J Pediatr , vol.155 , pp. 20-25
    • Muller, F.M.1    Ehrenthal, W.2    Hafner, G.3
  • 17
    • 0035479232 scopus 로고    scopus 로고
    • Activity and antigen levels of thrombin-activatable fibrinolysis inhibitor in plasma of patients with disseminated intravascular coagulation
    • Watanabe R, Wada H, Watanabe Y, et al: Activity and antigen levels of thrombin-activatable fibrinolysis inhibitor in plasma of patients with disseminated intravascular coagulation. Thromb Res 2001; 104:1-6
    • (2001) Thromb Res , vol.104 , pp. 1-6
    • Watanabe, R.1    Wada, H.2    Watanabe, Y.3
  • 18
    • 0034985020 scopus 로고    scopus 로고
    • An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation
    • Asakura H, Ontachi Y, Mizutani T, et al: An enhanced fibrinolysis prevents the development of multiple organ failure in disseminated intravascular coagulation in spite of much activation of blood coagulation. Crit Care Med 2001; 29:1164-1168
    • (2001) Crit Care Med , vol.29 , pp. 1164-1168
    • Asakura, H.1    Ontachi, Y.2    Mizutani, T.3
  • 19
    • 23044459987 scopus 로고    scopus 로고
    • 4G/5G promoter polymorphism in the plasmino-gen-activator-inhibitor-1 gene in children with systemic meningococcaemia
    • Geishofer G, Binder A, Muller M, et al: 4G/5G promoter polymorphism in the plasmino-gen-activator-inhibitor-1 gene in children with systemic meningococcaemia. Eur J Pediatr 2005; 164:486-490
    • (2005) Eur J Pediatr , vol.164 , pp. 486-490
    • Geishofer, G.1    Binder, A.2    Muller, M.3
  • 20
    • 34548839906 scopus 로고    scopus 로고
    • 4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia
    • Binder A, Endler G, Muller M, et al: 4G4G genotype of the plasminogen activator inhibitor-1 promoter polymorphism associates with disseminated intravascular coagulation in children with systemic meningococcemia. J Thromb Haemost 2007; 5:2049-2054
    • (2007) J Thromb Haemost , vol.5 , pp. 2049-2054
    • Binder, A.1    Endler, G.2    Muller, M.3
  • 21
    • 0029415115 scopus 로고
    • Endotoxininduced intravascular coagulation in rabbits: Effect of tissue plasminogen activator vs urokinase of PAI generation, fibrin deposits and mortality
    • Paloma MJ, Paramo JA, Rocha E: Endotoxininduced intravascular coagulation in rabbits: Effect of tissue plasminogen activator vs urokinase of PAI generation, fibrin deposits and mortality. Thromb Haemost 1995; 74: 1578-1582
    • (1995) Thromb Haemost , vol.74 , pp. 1578-1582
    • Paloma, M.J.1    Paramo, J.A.2    Rocha, E.3
  • 22
    • 0033916564 scopus 로고    scopus 로고
    • Prevention of renal fibrin deposition in endotox-in-induced DIC through inhibition of PAI-1
    • Montes R, Declerck PJ, Calvo A, et al: Prevention of renal fibrin deposition in endotox-in-induced DIC through inhibition of PAI-1. Thromb Haemost 2000; 84:65-70
    • (2000) Thromb Haemost , vol.84 , pp. 65-70
    • Montes, R.1    Declerck, P.J.2    Calvo, A.3
  • 23
    • 0035904368 scopus 로고    scopus 로고
    • Caring for the critically ill patient. High-dose anti-thrombin III in severe sepsis: A randomized controlled trial
    • Warren BL, Eid A, Singer P, et al: Caring for the critically ill patient. High-dose anti-thrombin III in severe sepsis: A randomized controlled trial. JAMA 2001; 286:1869-1878
    • (2001) JAMA , vol.286 , pp. 1869-1878
    • Warren, B.L.1    Eid, A.2    Singer, P.3
  • 24
    • 33644859949 scopus 로고    scopus 로고
    • Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation
    • Kienast J, Juers M, Wiedermann CJ, et al: Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost 2006; 4:90-97
    • (2006) J Thromb Haemost , vol.4 , pp. 90-97
    • Kienast, J.1    Juers, M.2    Wiedermann, C.J.3
  • 25
    • 0037222911 scopus 로고    scopus 로고
    • High plasma fibrinogen level is associated with poor clinical outcome in DIC patients
    • Wada H, Mori Y, Okabayashi K, et al: High plasma fibrinogen level is associated with poor clinical outcome in DIC patients. Am J Hematol 2003; 72:1-7
    • (2003) Am J Hematol , vol.72 , pp. 1-7
    • Wada, H.1    Mori, Y.2    Okabayashi, K.3
  • 26
    • 0022545605 scopus 로고
    • Determination of soluble fibrin in plasma by a rapid and quantitative spectrophotometric assay
    • Wiman B, Ranby M: Determination of soluble fibrin in plasma by a rapid and quantitative spectrophotometric assay. Thromb Haemost 1986; 55:189-193
    • (1986) Thromb Haemost , vol.55 , pp. 189-193
    • Wiman, B.1    Ranby, M.2
  • 27
    • 0025356978 scopus 로고
    • Comparison of methods for detecting soluble fibrin in plasma. An in vitro study
    • Halvorsen S, Skjonsberg OH, Ruyter R, et al: Comparison of methods for detecting soluble fibrin in plasma. An in vitro study. Thromb Res 1990; 57:489-497
    • (1990) Thromb Res , vol.57 , pp. 489-497
    • Halvorsen, S.1    Skjonsberg, O.H.2    Ruyter, R.3
  • 28
    • 0027933704 scopus 로고
    • Soluble fibrin: A predictor for the development and outcome of multiple organ failure
    • Bredbacka S, Blomback M, Wiman B: Soluble fibrin: A predictor for the development and outcome of multiple organ failure. Am J Hematol 1994; 46:289-294
    • (1994) Am J Hematol , vol.46 , pp. 289-294
    • Bredbacka, S.1    Blomback, M.2    Wiman, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.