Intracortical excitability in patients with relapsing-remitting and secondary progressive multiple sclerosis

Journal of Neurology

Volumn 256, Issue 6, 2009, Pages 933-938

  Conte, A ^a,b   Lenzi, D ^a   Frasca, V ^a   Gilio, F ^c   Giacomelli, E ^a   Gabriele, M ^a   Marini Bettolo, C ^a   Iacovelli, E ^a   Pantano, P ^a   Pozzilli, C ^a   Inghilleri, M ^a,d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b IRCCS NEUROMED   (Italy)

^c SANDRO PERTINI HOSPITAL   (Italy)

^d SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

Intracortical excitability; Multiple sclerosis; Paired pulse transcranial magnetic stimulation

Indexed keywords

ADULT; ARTICLE; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; DISEASE COURSE; DISEASE SEVERITY; EVOKED MUSCLE RESPONSE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MOTOR CORTEX; MOTOR NERVE CONDUCTION; MULTIPLE SCLEROSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; RECURRENT DISEASE; REMISSION; TRANSCRANIAL MAGNETIC STIMULATION;

ADULT; ANALYSIS OF VARIANCE; ELECTROMYOGRAPHY; EVOKED POTENTIALS, MOTOR; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MOTOR CORTEX; MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NEURAL CONDUCTION; NEURAL INHIBITION; SEVERITY OF ILLNESS INDEX; TIME FACTORS; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 67650466999     PISSN: 03405354     EISSN: 14321459     Source Type: Journal    
DOI: 10.1007/s00415-009-5047-0     Document Type: Article

References (33)

1. A Berardelli M Inghilleri G Cruccu M Fornarelli N Accornero M Manfredi 1988 Stimulation of motor tract in multiple sclerosis J Neurol Neurosurg Psychiatry 51 677 683 (Pubitemid 18153763)
2. SJ Boniface 2001 Plasticity after acute ischaemic stroke studied by transcranial magnetic stimulation J Neurol Neurosurg Psychiatry 71 713 715 (Pubitemid 33121908)
3. M Calabrese M Atzori V Bernardi 2007 Cortical atrophy is relevant in multiple sclerosis at clinical onset J Neurol 254 1212 1220 (Pubitemid 350112349)
4. O Ciccarelli PA Brex AJ Thompson DH Miller 2002 Disability and lesion load in MS: a reassessment with MS functional composite score and 3D fast FLAIR J Neurol 249 18 24 (Pubitemid 34119019)
5. MD Caramia MG Palmieri MT Desiato 2004 Brain excitability changes in the relapsing and remitting phases of multiple sclerosis: a study with transcranial magnetic stimulation Clin Neurophysiol 15 956 965 (Pubitemid 38293495)
6. J Classen A Schnitzler F Binkofski 1997 The motor syndrome associated with exaggerated inhibition within the primary motor cortex of patients with hemiparetic stroke Brain 120 605 619 (Pubitemid 27174096)
7. A Curra N Modugno M Inghilleri M Manfredi M Hallett A Berardelli 2002 Transcranial magnetic stimulation techniques in clinical investigation Neurology 59 1851 1859 (Pubitemid 36076554)
8. J Dehmeshki DT Chard SM Leary 2003 The normal appearing grey matter in primary progressive multiple sclerosis: a magnetisation transfer imaging study J Neurol 250 67 74 (Pubitemid 36206687)
9. D Facchetti R Mai A Micheli 1997 Motor evoked potentials and disability in secondary progressive multiple sclerosis Can J Neurol Sci 24 332 337 (Pubitemid 28064761)
10. B Fierro G Salemi F Brighina 2002 A transcranial magnetic stimulation study evaluating methylprednisolone treatment in multiple sclerosis Acta Neurol Scand 105 152 157 (Pubitemid 34258954)
11. P Fuhr L Kappos 2001 Evoked potentials for evaluation of multiple sclerosis Clin Neurophysiol 112 2185 2189 (Pubitemid 33153140)
12. GJ Geurts F Barkhof 2008 Grey matter pathology in multiple sclerosis Lancet Neurol 7 841 851
13. J Grimaud M Lai J Thorpe 1996 Quantification of MRI lesion load in multiple sclerosis: a comparison of three computer-assisted techniques Magn Reson Imaging 14 495 505 (Pubitemid 26274841)
14. J Hobart N Kalkers F Barkhof B Uitdehaag C Polman A Thompson 2004 Outcome measures for multiple sclerosis clinical trials: relative measurement precision of the expanded disability status scale and multiple sclerosis functional composite Mult Scler 10 41 46 (Pubitemid 38100525)
15. AM Humm A Truffert MR Magistris KM Rösler 2002 Central motor conduction in acute relapsing-remitting versus chronic progressive multiple sclerosis J Neurol 249 I/101 I/102
16. AM Humm MR Magistris A Truffert CW Hess KM Rösler 2003 Central motor conduction differs between acute relapsing-remitting and chronic progressive multiple sclerosis Clin Neurophysiol 114 2196 2203 (Pubitemid 37298069)
17. AM Humm WJ Z'Graggen R Bühler MR Magistris KM Rösler 2006 Quantification of central motor conduction deficits in multiple sclerosis patients before and after treatment of acute exacerbation by methylprednisolone J Neurol Neurosurg Psychiatry 77 345 350 (Pubitemid 43295156)
18. RH Kandler JA Jarratt GA Davies-Jones 1991 The role of magnetic stimulation as a quantifier of motor disability in patients with multiple sclerosis J Neurol Sci 106 31 34
19. Z Khaleeli M Cercignani B Audoin 2007 Localized grey matter damage in early primary progressive multiple sclerosis contributes to disability Neuroimage 37 253 261 (Pubitemid 47068988)
20. D Kidd PD Thompson BL Day 1998 Central motor conduction time in progressive multiple sclerosis. Correlations with MRI and disease activity Brain 121 1109 1116 (Pubitemid 28256984)
21. T Kujirai MD Caramia JC Rothwell 1993 Corticocortical inhibition in human motor cortex J Physiol 471 501 519 (Pubitemid 23345592)
22. JF Kurtzke 1983 Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS) Neurology 33 1444 1452 (Pubitemid 14237132)
23. J Liepert D Mingers C Heesen T Baumer C Weiller 2005 Motor cortex excitability and fatigue in multiple sclerosis: a transcranial magnetic stimulation study Mult Scler 11 316 321 (Pubitemid 40775189)
24. FD Lublin SC Reingold 1996 Defining the clinical course of multiple sclerosis: results of an international survey. National Multiple Sclerosis Society (USA) Advisory Committee on clinical trials of new agents in multiple sclerosis Neurology 46 907 911
25. C Mainero M Inghilleri P Pantano 2004 Enhanced brain motor activity in patients with MS after a single dose of 3,4-diaminopyridine Neurology 62 2044 2050 (Pubitemid 38738219)
26. M Masek M Vaneckova J Krasensky 2008 Secondary-progressive form of multiple sclerosis: MRI changes versus clinical status Neuro Endocrinol Lett 29 461 466
27. C Oreja-Guevara A Charil D Caputo 2006 Magnetization transfer magnetic resonance imaging and clinical changes in patients with relapsing-remitting multiple sclerosis Arch Neurol 63 736 740
28. M Rovaris E Judica A Gallo 2006 Grey matter damage predicts the evolution of primary progressive multiple sclerosis at 5 years Brain 129 2628 2634 (Pubitemid 44522096)
29. K Schmierer K Irlbacher P Grosse S Röricht BU Meyer 2002 Correlates of disability in multiple sclerosis detected by transcranial magnetic stimulation Neurology 59 1218 1224 (Pubitemid 35192392)
30. GL Sheean NMF Murray JC Rothwell DH Miller AJ Thompson 1997 An electrophysiological study of the mechanism of fatigue in multiple sclerosis Brain 120 299 315 (Pubitemid 27107663)
31. Talairach J, Tournoux P (1988) Coplanar stereotaxic atlas of the human brain. Thieme, Stuttgart
32. CA Tassinari M Cincotta G Zaccara R Michelacci 2003 Transcranial magnetic stimulation and epilepsy Clin Neurophysiol 114 777 798 (Pubitemid 36556090)
33. H Vrenken PJ Pouwels JJ Geurts 2006 Altered diffusion tensor in multiple sclerosis normal-appearing brain tissue: cortical diffusion changes seem related to clinical deterioration J Magn Reson Imaging 23 628 636