Upstream high-dose tirofiban does not reduce myocardial infarct size in patients undergoing primary percutaneous coronary intervention: A magnetic resonance imaging pilot study

Clinical Cardiology

Volumn 32, Issue 6, 2009, Pages 321-326

  Young, Bin Song ^a   Hahn, Joo Yong ^a   Gwon, Hyeon Cheol ^a   Jun, Hyung Kim ^a   Sang, Yeub Lee ^a   Yeon, Hyeon Choe ^a   Choi, Seung Hyuk ^a   Choi, Jin Ho ^a   Sang, Hoon Lee ^a  

^a Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ABCIXIMAB; ACETYLSALICYLIC ACID; CLOPIDOGREL; GADOLINIUM PENTETATE; HEPARIN; RETEPLASE; TIROFIBAN;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTRAST ENHANCEMENT; CONTROL GROUP; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG MEGADOSE; ECHOCARDIOGRAPHY; FEMALE; FIBRINOLYTIC THERAPY; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; MAINTENANCE THERAPY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCUTANEOUS CORONARY INTERVENTION; PILOT STUDY; RANDOMIZED CONTROLLED TRIAL; ST SEGMENT ELEVATION; THERAPY DELAY;

AGED; ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY; CONTRAST MEDIA; CORONARY ANGIOGRAPHY; CORONARY CIRCULATION; ECHOCARDIOGRAPHY; FEMALE; GADOLINIUM DTPA; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIUM; PILOT PROJECTS; PLATELET AGGREGATION INHIBITORS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; STENTS; STROKE VOLUME; TIME FACTORS; TREATMENT OUTCOME; TYROSINE; VENTRICULAR FUNCTION, LEFT;

EID: 67650463008     PISSN: 01609289     EISSN: None     Source Type: Journal    
DOI: 10.1002/clc.20551     Document Type: Article

References (21)

1. Gunasekara AP, Walters DL, Aroney CN. Comparison of abciximab with "high-dose" tirofiban in patients undergoing percutaneous coronary intervention. Int J Cardiol. 2006;109:16-20.
2. van 't Hof AW, Ernst N, de Boer MJ, et al. Facilitation of primary coronary angioplasty by early start of a glycoprotein IIb/IIIa inhibitor: results of the ongoing tirofiban in myocardial infarction evaluation (On-TIME) trial. Eur Heart J. 2004;25:837-846. (Pubitemid 38679942)
3. Ernst NM, Suryapranata H, Miedema K, et al. Achieved platelet aggregation inhibition after different antiplatelet regimens during percutaneous coronary intervention for ST-segment elevation myocardial infarction. J Am Coll Cardiol. 2004;44:1187-1193. (Pubitemid 39208872)
4. Valgimigli M, Percoco G, Barbieri D, et al. The additive value of tirofiban administered with the high-dose bolus in the prevention of ischemic complications during high-risk coronary angioplasty: the ADVANCE Trial. J Am Coll Cardiol. 2004;44:14-19. (Pubitemid 38968448)
5. Montalescot G, Borentain M, Payot L, Collet JP, Thomas D. Early vs late administration of glycoprotein IIb/IIIa inhibitors in primary percutaneous coronary intervention of acute ST-segment elevation myocardial infarction: a meta-analysis. JAMA. 2004;292:362-366. (Pubitemid 38944261)
6. Thiele H, Kappl MJ, Conradi S, Niebauer J, Hambrecht R, Schuler G. Reproducibility of chronic and acute infarct size measurement by delayed enhancement-magnetic resonance imaging. J Am Coll Cardiol. 2006;47:1641-1645.
7. Gersh BJ, Anderson JL. Thrombolysis and myocardial salvage. Results of clinical trials and the animal paradigm-paradoxic or predictable? Circulation. 1993;88:296-306. (Pubitemid 23195459)
8. Claeys MJ, Bosmans J, Veenstra L, Jorens P, De Raedt H, Vrints CJ. Determinants and prognostic implications of persistent STsegment elevation after primary angioplasty for acute myocardial infarction: importance of microvascular reperfusion injury on clinical outcome. Circulation. 1999;99:1972-1977. (Pubitemid 29183893)
9. van 't Hof AW, Liem A, Suryapranata H, Hoorntje JC, de Boer MJ, Zijlstra F. Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Zwolle Myocardial Infarction Study Group. Circulation. 1998;97:2302-2306.
10. Hahn JY, Gwon HC, Choe YH, et al. Effects of balloon-based distal protection during primary percutaneous coronary intervention on early and late infarct size and left ventricular remodeling: a pilot study using serial contrast-enhanced magnetic resonance imaging. Am Heart J. 2007;153:665 e661-668. (Pubitemid 46440693)
11. Choe YH, Choo KS, Jeon ES, Gwon HC, Choi JH, Park JE. Comparison of MDCT and MRI in the detection and sizing of acute and chronic myocardial infarcts. Eur J Radiol. 2008;66:292-299. (Pubitemid 351626400)
12. Kim RJ, Wu E, Rafael A, et al. The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl JMed. 2000;343:1445-1453. (Pubitemid 30832880)
13. Martin ET, Fuisz AR, Pohost GM. Imaging cardiac structure and pump function. Cardiol Clin. 1998;16:135-160. (Pubitemid 28249197)
14. Orn S, Manhenke C, Anand IS, et al. Effect of left ventricular scar size, location, and transmurality on left ventricular remodeling with healed myocardial infarction. Am J Cardiol. 2007;99:1109-1114. (Pubitemid 46560460)
15. Batchelor WB, Tolleson TR, Huang Y, et al. Randomized comparison of platelet inhibition with abciximab, tirofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes: the COMPARE trial. Comparison of measurements of platelet aggregation with aggrastat, reopro, and eptifibatide. Circulation. 2002;106:1470-1476.
16. Ellis SG, Tendera M, de Belder MA, et al. Facilitated PCI in patients with ST-elevation myocardial infarction. N Engl J Med. 2008;358():2205-2217. (Pubitemid 351724450)
17. Stone GW, Cox D, Garcia E, et al. Normal flow (TIMI-3) before mechanical reperfusion therapy is an independent determinant of survival in acute myocardial infarction: analysis from the primary angioplasty in myocardial infarction trials. Circulation. 2001;104:636-641. (Pubitemid 32738515)
18. Kim RJ, Fieno DS, Parrish TB, et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation. 1999;100:1992-2002. (Pubitemid 29529292)
19. Beek AM, Kuhl HP, Bondarenko O, et al. Delayed contrast-enhanced magnetic resonance imaging for the prediction of regional functional improvement after acute myocardial infarction. J Am Coll Cardiol. 2003;42:895-901. (Pubitemid 37059750)
20. Mahrholdt H, Wagner A, Holly TA, et al. Reproducibility of chronic infarct size measurement by contrast-enhanced magnetic resonance imaging. Circulation. 2002;106:2322-2327. (Pubitemid 35244732)
21. Steen H, Lehrke S, Wiegand UK, et al. Very early cardiac magnetic resonance imaging for quantification ofmyocardial tissue perfusion in patients receiving tirofiban before percutaneous coronary intervention for ST-elevation myocardial infarction. Am Heart J. 2005;149(564):e561-e567. (Pubitemid 40585422)