Successful topical treatment of sorafenib-induced hand-foot skin reaction in a child with hepatocellular carcinoma

Pediatric Dermatology

Volumn 26, Issue 3, 2009, Pages 349-350

  HÜtten, Matthias ^a   Lassay, Lisa ^a   Sachs, Bernhardt ^a   Deutz, Peter ^a   Mertens, Roland ^a   Baron, Jens Malte ^b   Merk, Hans Friedrich ^b   Ott, Hagen ^a,b  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b FEDERAL INSTITUTE FOR DRUGS AND MEDICAL DEVICES   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DEXPANTHENOL; FUSIDIC ACID; PREDNICARBATE; SORAFENIB;

ADOLESCENT; ARTICLE; CANCER CHEMOTHERAPY; CANCER RELAPSE; CANCER SURGERY; CASE REPORT; CHEILITIS; CHILDHOOD CANCER; DRUG TOLERABILITY; HAND FOOT SYNDROME; HUMAN; INFLAMMATION; LIVER CELL CARCINOMA; MALE; PARONYCHIA; PRIORITY JOURNAL; SKIN BIOPSY; TREATMENT RESPONSE;

ADOLESCENT; ANTINEOPLASTIC AGENTS; BENZENESULFONATES; CARCINOMA, HEPATOCELLULAR; FOOT DERMATOSES; HAND DERMATOSES; HUMANS; LIVER NEOPLASMS; MALE; PROTEIN KINASE INHIBITORS; PYRIDINES;

EID: 67650457929     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2009.00933.x     Document Type: Article

References (8)

1. Llovet JM, Ricci S, Mazzaferro V et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med 2008 359 : 378 390.
2. Yang CH, Lin WC, Chuang CK et al. Hand-foot skin reaction in patients treated with sorafenib: a clinicopathological study of cutaneous manifestations due to multitargeted kinase inhibitor therapy. Br J Dermatol 2008 158 : 592 596.
3. Lacouture ME, Reilly LM, Gerami P et al. Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib. Ann Oncol 2008 19 : 1955 1961.
4. Autier J, Escudier B, Wechsler J et al. Prospective study of the cutaneous adverse effects of sorafenib, a novel multikinase inhibitor. Arch Dermatol 2008 144 : 886 892. (Pubitemid 352039741)
5. Hong DS, Reddy SB, Prieto VG et al. Multiple squamous cell carcinomas of the skin after therapy with sorafenib combined with tipifarnib. Arch Dermatol 2008 144 : 779 782. (Pubitemid 351846880)
6. Richetta AG, Maiani E, Carboni V et al. Sorafenib: atypical cutaneous side effects. Eur J Dermatol 2007 17 : 549 550. (Pubitemid 350207179)
7. Lacouture ME, Wu S, Robert C et al. Evolving strategies for the management of hand-foot skin reaction associated with the multitargeted kinase inhibitors sorafenib and sunitinib. Oncologist 2008 13 : 1001 1011.
8. Chu D, Lacouture ME, Fillos T et al. Risk of hand-foot skin reaction with sorafenib: a systematic review and meta-analysis. Acta Oncol 2008 47 : 176 186.