Myrrh and trematodoses in Egypt: An overview of safety, efficacy and effectiveness profiles

Parasitology International

Volumn 58, Issue 3, 2009, Pages 210-214

  Abdul Ghani, Rashad A ^a   Loutfy, Naguiba ^b   Hassan, Azza ^b  

^a SANA A UNIVERSITY   (Yemen)

^b High Institute of Public Health Egypt   (Egypt)

Author keywords

Mirazid; Molluscicidal; Myrrh; Trematodicidal

Indexed keywords

FASCIOLICIDE; HERBACEOUS AGENT; MIRAZID; MOLLUSCACIDE; MYRRH; UNCLASSIFIED DRUG;

DICROCOELIASIS; DRUG ACTIVITY; DRUG EFFICACY; DRUG SAFETY; EGYPT; EVIDENCE BASED PRACTICE; FASCIOLIASIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCHISTOSOMIASIS; TREMATODE; TREMATODIASIS;

ANIMALS; ANTIPARASITIC AGENTS; CLINICAL TRIALS AS TOPIC; COMMIPHORA; EGYPT; FASCIOLA; HUMANS; MICE; PHYTOTHERAPY; PLANT EXTRACTS; SCHISTOSOMA MANSONI; SNAILS; TREATMENT OUTCOME; TREMATODE INFECTIONS;

COMMIPHORA; TREMATODA;

EID: 67650455889     PISSN: 13835769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parint.2009.04.006     Document Type: Review

References (34)

1. Lardos A. The botanical materia medica of the latrosophikon-a collection of prescriptions from a monastery in Cyprus. J Ethnopharmacol 104 (2006) 387-406
2. Greene D.A. Gold, frankincense, myrrh and, medicine. N C Med J 54 (1993) 620-622
3. Hanus L.O., Rezanka T., Dembitsky V.M., and Moussaieff A. Myrrh-Commiphora chemistry. Biomed Pap Med Univ Palacký Olomouc, Czech Repub 149 (2005) 3-27
4. Dekebo A., Dagne E., and Sterner O. Furanosesquiterpenes from Commiphorasphaerocarpa and related adulterants of true myrrh. Fitoterapia 73 (2002) 48-55
5. Michie C.A., and Cooper E. Frankincense and myrrh as remedies in children. J R Soc Med 84 (1991) 602-605
6. Nomicos E.Y.H. Myrrh: medical marvel or myth of the Magi?. Holist Nurs Pract 21 (2007) 308-323
7. Ford R.A., Api M.A., and Letizia C.S. Monographs on fragrance raw materials. Food Chem Toxicol 30 (1992) 1S-138S
8. Massoud A., Salama O., and Bennet J. Therapeutic efficacy of a new schistosomicidal drug, derived from myrrh, in active intestinal schistosomiasis complicated with hepatosplenomegaly. Parasitol Int 47 (1998) 125
9. Massoud A., El Sisi S., Salama O., and Massoud A. Preliminary study of therapeutic efficacy of a new fasciolicidal drug derived from Commiphora molmol (myrrh). Am J Trop Med Hyg 65 (2001) 96-99
10. Massoud A.M., El Ebiary F.H., and Abd El Salam N.F. Effect of myrrh extract on the liver of normal and bilharzially infected mice. An ultrastructural study. J Egypt Soc Parasitol 34 (2004) 1-21
11. Omar A., Elmesallamy G.E., and Eassa S. Comparative study of the hepatotoxic, genotoxic and carcinogenic effects of praziquantel distocide and the natural myrrh extract Mirazid on adult male albino rats. J Egypt Soc Parasitol 35 (2005) 313-329
12. Badria F., Abou Mohamed G., El-Mowafy A., Massoud A., and Salama O. Mirazid: a new schistosomicidal drug. Pharmaceut Biol 93 (2001) 127-131
13. Hassan M., El-Motaiem M., Afify H., Abaza B., El-Shafei M., and Massoud A.M. In vitro effect of Mirazid on Schistosoma mansoni worms. J Egypt Soc Parasitol 33 (2003) 999-1008
14. Fenwick A., Savioli L., Engels D., Robert B.N., and Todd M.H. Drugs for the control of parasitic diseases: current status and development in schistosomiasis. Trends Parasitol 19 (2003) 509-515
15. Hamed M.A., and Hetta M.H. Efficacy of Citrus reticulata and Mirazid in treatment of Schistosoma mansoni. Mem Inst Oswaldo Cruz 100 (2005) 771-778
16. Massoud A.M., El Ebiary F.H., Abou-Gamra M.M., Mohamed G.F., and Shaker S.M. Evaluation of schistosomicidal activity of myrrh extract: parasitological and histological study. J Egypt Soc Parasitol 34 (2004) 1051-1076
17. Botros S., William S., Ebeid F., Cioli D., Katz N., Day T.A., et al. Lack of evidence for an antischistosomal activity of myrrh in experimental animals. Am J Trop Med Hyg 71 (2004) 206-210
18. Sheir Z., Nasr A.A., Massoud A., Salama O., Badra G.A., El-Shennawy H., et al. A safe, effective, herbal antischistosomal therapy derived from myrrh. Am J Trop Med Hyg 65 (2001) 700-704
19. Abo-Madyan A.A., Morsy T.A., and Motawea S.M. Efficacy of myrrh in the treatment of schistosomiasis (haematobium and mansoni) in Ezbet El-Bakly, Tamyia Center, El-Fayoum Governorate, Egypt. J Egypt Soc Parasitol 34 (2004) 423-446
20. Soliman O.E., El-Arman M., Abdul-Samie E.R., El-Nemr H.I., and Massoud A. Evaluation of myrrh (Mirazid) therapy in fascioliasis and intestinal schistosomiasis in children: immunological and parasitological study. J Egypt Soc Parasitol 34 (2004) 941-966
21. Barakat R., Elmorshedy H., and Fenwick A. Efficacy of myrrh in the treatment of human Schistosomiasis mansoni. Am J Trop Med Hyg 73 (2005) 365-367
22. El Baz M.A.., Morsy T.A., El Bandary M.M., and Motawea S.M. Clinical and parasitological studies on the efficacy of Mirazid in treatment of schistosomiasis haematobium in Tatoon, Etsa Center, El Fayoum Governorate. J Egypt Soc Parasitol 33 (2003) 761-776
23. Botros S.., Sayed H., El-Dusoki H., Sabry H., Rabie I., El-Ghannam M., et al. Efficacy of mirazid in comparison with praziquantel in Egyptian Schistosoma mansoni-infected school children and households. Am J Trop Med Hyg 72 (2005) 119-123
24. ®. Res J Parasitol 3 (2008) 40-49
25. Hegab M.H., and Hassan R.M. Role of circulating Fasciola antigens and IgG4 isotype in assessment of cure from fascioliasis. J Egypt Soc Parasitol 33 (2003) 561-570
26. Abo-Madyan A.A., Morsy T.A., Motawea S.M., and Morsy A.T. Clinical trial of Mirazid in treatment of human fascioliasis, Ezbet El-Bakly (Tamyia Center) Al-Fayoum Governorate. J Egypt Soc Parasitol 34 (2004) 807-818
27. Fathy F.M., Salama O., and Massoud A.M. Effect of Mirazid (Commiphora molmol) on experimental heterophyidiasis. J Egypt Soc Parasitol 35 (2005) 1037-1050
28. Massoud A.M., El-Shazly A.M., and Morsy T.A. Mirazid (Commiphora molmol) in treatment of human heterophyiasis. J Egypt Soc Parasitol 37 (2007) 395-410
29. Haridy F.M., Morsy T.A., Ibrahim B.B., and Abdel-Aziz A. A preliminary study on dicrocoeliasis in Egypt, with a general review. J Egypt Soc Parasitol 33 (2003) 85-96
30. Massoud A., Morsy T.A., and Haridy F.M. Treatment of Egyptian dicrocoeliasis in man and animals with Mirazid. J Egypt Soc Parasitol 33 (2003) 437-442
31. Al-Mathal E.M., and Fouad M.A. Myrrh (Commiphora molmol) in treatment of human and sheep dicrocoeliasis dendriticum in Saudi Arabia. J Egypt Soc Parasitol 34 2 (2004) 713-720
32. Allam A.F., el-Sayad M.H., and Khalil S.S. Laboratory assessment of the molluscicidal activity of Commiphora molmol (Myrrh) on Biomphalaria alexandrina, Bulinus truncatus and Lymnaea cailliaudi. J Egypt Soc Parasitol 31 (2001) 683-690
33. Massoud A.M., and Habib F.S. The effects of myrrh (Commiphora molmol) on the infected snails of Schistosoma sp. and their egg masses: effect on shedding of cercariae and on snail fecundity. J Egypt Soc Parasitol 33 (2003) 585-596
34. Massoud A.M., Metwally D.M., Khalifa K.E., and Habib F.S. Compatibility of Biomphalaria alexandrina snails to infection with Schistosoma mansoni after exposure to sublethal concentrations of Myrrh. J Egypt Soc Parasitol 34 (2004) 995-1008