The relationship between the IC50, toxic threshold, and the magnitude of stimulatory response in biphasic (hormetic) dose-responses

Regulatory Toxicology and Pharmacology

Volumn 54, Issue 3, 2009, Pages 229-233

  Nascarella, Marc A ^a,b   Calabrese, Edward J ^b  

^a GRADIENT   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Cancer; Chemotherapy; Delta X; Dose response; Hormesis; IC50; Toxic potency; Yeast

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DRUG EXPOSURE; HIGH THROUGHPUT SCREENING; HORMESIS; IC 50; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; TOXICITY TESTING;

ANTINEOPLASTIC AGENTS; DATA INTERPRETATION, STATISTICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; INHIBITORY CONCENTRATION 50; MODELS, BIOLOGICAL; SACCHAROMYCES CEREVISIAE;

EID: 67650450835     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2009.04.005     Document Type: Article

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