The ALS/PDC syndrome of guam and the cycad hypothesis

Neurology

Volumn 72, Issue 5, 2009, Pages 473-

  Borenstein, Amy R ^a   Mortimer, James A ^a   Schellenberg, Gerard D ^a   Galasko, Douglas ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID; PLANT EXTRACT;

AMYOTROPHIC LATERAL SCLEROSIS; CAUSAL ATTRIBUTION; ENVIRONMENTAL EXPOSURE; EXCITOTOXICITY; FLOUR; GUAM; HUMAN; LETTER; MORBIDITY; NONHUMAN; PARKINSON DISEASE; PREVALENCE; PRIORITY JOURNAL; RETINITIS; CHEMISTRY; CYCAS; DANGEROUS GOODS; DEMENTIA; EPIDEMIOLOGY; FEMALE; INCIDENCE; MALE; NOTE; PARKINSONISM; SEX RATIO; STATISTICAL ANALYSIS; SYNDROME;

AMYOTROPHIC LATERAL SCLEROSIS; CAUSALITY; CYCAS; DATA INTERPRETATION, STATISTICAL; DEMENTIA; EPIDEMIOLOGIC RESEARCH DESIGN; EPIDEMIOLOGIC STUDIES; FEMALE; FLOUR; GUAM; HAZARDOUS SUBSTANCES; HUMANS; INCIDENCE; MALE; PARKINSONIAN DISORDERS; PLANT EXTRACTS; SEX DISTRIBUTION; SYNDROME;

MLCS; MLOWN;

EID: 67650446016     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/01.wnl.0000344257.59693.cf     Document Type: Letter

References (5)

1. JC Steele PL McGeer The ALS/PDC syndrome of Guam and the cycad hypothesis Neurology 70 2008 1984 1990
2. CC Plato RM Garruto D Galasko Amyotrophic lateral sclerosis and Parkinsonism-dementia complex of Guam: changing incidence rates during the past 60 years Am J Epidemiol 157 2003 149 157
3. D Galasko D Salmon A Gamst Prevalence of dementia in Chamorros on Guam: relationship to age, gender, education and APOE Neurology 68 2007 1772 1781
4. AR Borenstein E Mortimer E Schofield Cycad exposure and risk of dementia, MCI and PDC in the Chamorro population of Guam Neurology 68 2007 1764 1771
5. J Wilson CA Shaw Commentary on: Return of the cycad hypothesis: does the amyotrophic lateral sclerosis/parkinsonism dementia complex (ALS/PDC) of Guam have new implications for global health? Neuropathol Appl Neurobiol 32 2006 341 343