Calcium-activated chloride currents prolongs the duration of contractions in pregnant rat myometrial tissue

Reproductive Sciences

Volumn 16, Issue 8, 2009, Pages 734-739

  Young, Roger C ^a   Bemis, Adam ^b  

^a UNIVERSITY OF VERMONT   (United States)

^b BIO RAD LABORATORIES   (United States)

Author keywords

Chloride channels; Chlorotoxin; ICl(Ca); Myometrium; Nifedipine

Indexed keywords

9 ANTHROIC ACID; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CHLORIDE; CHLORIDE CHANNEL BLOCKING AGENT; CHLOROTOXIN; NIFEDIPINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CALCIUM ACTIVATED CHLORIDE CURRENT; CHLORIDE CURRENT; CONTROLLED STUDY; DRUG MECHANISM; ELECTRODE; FEMALE; LOW DRUG DOSE; MUSCLE FORCE; MYOMETRIUM; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE; UTERINE ATONY; UTERUS CONTRACTILITY; UTERUS RELAXATION;

ANIMALS; ANTHRACENES; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS, L-TYPE; CHLORIDE CHANNELS; CHLORIDES; FEMALE; MEMBRANE POTENTIALS; MUSCLE STRENGTH; MYOMETRIUM; NIFEDIPINE; PREGNANCY; RATS; SCORPION VENOMS; TIME FACTORS; UTERINE CONTRACTION;

EID: 67650422186     PISSN: 19337191     EISSN: 19337205     Source Type: Journal    
DOI: 10.1177/1933719109334965     Document Type: Article

References (19)

1. Shmygol A., Blanks AM, Bru-Mercier G., Gullam JE, Thornton S. Control of uterine Ca2+ by membrane voltage: toward understanding the excitation- contraction coupling in human myometrium. Ann N Y Acad Sci. 2007 ; 1101: 97-109. (Pubitemid 47092718)
2. Okabe K., Inoue Y., Kawarabayashi T., Kajiya H., Okamoto F., Soeda H. Physiological significance of hyperpolarization-activated inward currents (Ih) in smooth muscle cells from the circular layers of pregnant rat myometrium. Pflugers Arch. 1999 ; 439 (1-2). 76-85. (Pubitemid 30055510)
3. Pressman EK, Tucker JA Jr, Anderson NC Jr, Young RC Morphologic and electrophysiologic characterization of isolated pregnant human myometrial cells. Am J Obstet Gynecol. 1988 ; 159 (5). 1273-1279. (Pubitemid 19002472)
4. Young RC Myocytes, myometrium, and uterine contractions. Ann N Y Acad Sci. 2007 ; 1101: 72-84. (Pubitemid 47092724)
5. Kuriyama H., Suzuki H. Changes in electrical properties of rat myometrium during gestation and following hormonal treatments. J Physiol. 1976 ; 260 (2). 315-333.
6. Mollard P., Mironneau J., Amedee T., Mironneau C. Electrophysiological characterization of single pregnant rat myometrial cells in short-term primary culture. Am J Physiol. 1986 ; 250 (1 pt 1). C47 - C54.
7. Coleman HA, Parkington HC Induction of prolonged excitability in myometrium of pregnant guinea-pigs by prostaglandin F2 alpha. J Physiol. 1988 ; 399: 33-47. (Pubitemid 18103664)
8. Wilde DW, Marshall JM Effects of tetraethylammonium and 4-aminopyridine on the plateau potential of circular myometrium from the pregnant rat. Biol Reprod. 1988 ; 38 (4). 836-845. (Pubitemid 18201093)
9. Parkington HC, Coleman HA Ionic mechanisms underlying action potentials in myometrium. Clin Exp Pharmacol Physiol. 1988 ; 15 (9). 657-665. (Pubitemid 18228164)
10. Kaya T., Guvenal T., Karadas B., Cetin A., Soydan AS Effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid, anthracene-9-carboxylate, and zaprinast on endothelin-1-induced contractions of pregnant rat myometrium. Eur J Obstet Gynecol Reprod Biol. 2002 ; 105 (2). 114-119.
11. Yarar Y., Cetin A., Kaya T. Chloride channel blockers 5-nitro-2-(3-phenylpropylamino) benzoic acid and anthracene-9-carboxylic acid inhibit contractions of pregnant rat myometrium in vitro. J Soc Gynecol Investig. 2001 ; 8 (4). 206-209. (Pubitemid 32768696)
12. Jones K., Shmygol A., Kupittayanant S., Wray S. Electrophysiological characterization and functional importance of calcium-activated chloride channel in rat uterine myocytes. Pflugers Arch. 2004 ; 448 (1). 36-43. (Pubitemid 38657203)
13. Pacaud P., Loirand G., Gregoire G., Mironneau C., Mironneau J. Calcium-dependence of the calcium-activated chloride current in smooth muscle cells of rat portal vein. Pflugers Arch. 1992 ; 421 (2-3). 125-130.
14. Piper AS, Greenwood IA Anomalous effect of anthracene-9-carboxylic acid on calcium-activated chloride currents in rabbit pulmonary artery smooth muscle cells. Br J Pharmacol. 2003 ; 138 (1). 31-38. (Pubitemid 36194200)
15. Hogg RC, Wang Q., Large WA Effects of Cl channel blockers on Ca-activated chloride and potassium currents in smooth muscle cells from rabbit portal vein. Br J Pharmacol. 1994 ; 111 (4). 1333-1341. (Pubitemid 24148810)
16. Dalton S., Gerzanich V., Chen M., Dong Y., Shuba Y., Simard JM Chlorotoxin-sensitive Ca2+-activated Clchannel in type R2 reactive astrocytes from adult rat brain. Glia. 2003 ; 42 (4). 325-339. (Pubitemid 36702273)
17. Lamont RF, Khan KS, Beattie B., et al. The quality of nifedipine studies used to assess tocolytic efficacy: a systematic review. J Perinat Med. 2005 ; 33 (4). 287-295. (Pubitemid 41205861)
18. Longo M., Jain V., Vedernikov YP, Hankins GD, Garfield RE, Saade GR Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour. Mol Hum Reprod. 2003 ; 9 (3). 159-164. (Pubitemid 36503456)
19. Ruttner Z., Ivanics T., Slaaf DW, Reneman RS, Toth A., Ligeti L. In vivo monitoring of intracellular free calcium changes during uterine activation by prostaglandin f(2alpha) and oxytocin. J Soc Gynecol Investig. 2002 ; 9 (5). 294-298. (Pubitemid 35292298)