Boosted expression of the SARS-CoV nucleocapsid protein in tobacco and its immunogenicity in mice

Vaccine

Volumn 27, Issue 36, 2009, Pages 5001-5007

  Zheng, Nuoyan ^a,b   Xia, Ran ^a   Yang, Cuiping ^b   Yin, Bojiao ^a,b   Li, Yin ^b   Duan, Chengguo ^a   Liang, Liming ^b   Guo, Huishan ^a   Xie, Qi ^a  

^a INSTITUTE OF GENETICS AND DEVELOPMENTAL BIOLOGY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

Cytokines regulation; Humoral response; Nucleocapsid protein; Plant based vaccine; SARS CoV

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 4; NUCLEOCAPSID PROTEIN; PLANT EXTRACT; PROTEIN P19;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNOGENICITY; MOUSE; NICOTIANA BENTHAMIANA; NONHUMAN; NUCLEOTIDE SEQUENCE; PLANT LEAF; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SARS CORONAVIRUS; TOBACCO; TOMATO;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; FEMALE; FREUND'S ADJUVANT; GENE SILENCING; HUMANS; IMMUNOGLOBULIN G; INJECTIONS, INTRAPERITONEAL; INTERFERON-GAMMA; INTERLEUKIN-10; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; NUCLEOCAPSID PROTEINS; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS; SARS VIRUS; SPLEEN; TOBACCO; TOMBUSVIRUS; VACCINES, SUBUNIT;

EID: 67650422005     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.073     Document Type: Article

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